Butylamine supplier | CasNO.109-73-9

Name
Butylamine
EINECS 203-699-2
CAS No. 109-73-9
Article Data339
CAS DataBase
Density 0.744 g/cm³
Solubility MISCIBLE
Melting Point -49 °C(lit.)
Formula C₄H₁₁N
Boiling Point 77.3 °C at 760 mmHg
Molecular Weight 73.138
Flash Point 30°F
Transport Information
Appearance colourless to yellow liquid
Safety 3-16-26-29-36/37/39-45
Risk Codes 11-20/21/22-35
Molecular Structure
Hazard Symbols F,C
Synonyms 1-Butanamine;1-Amino-butaan;1-Aminobutan;1-Aminobutane;1-Butanamine;CCRIS 4756;FEMA No. 3130;
PSA 26.02000
LogP 1.44550

Synthetic route

: 2565-54-0
(E)-2-((butylimino)methyl)phenol

: 108-91-8
cyclohexylamine

A: 19028-72-9
N-(2-hydroxybenzylidene)cyclohexylamine

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
In [D3]acetonitrile at 25℃; Equilibrium constant; Molecular sieve;	A 100% B n/a

...Expand

: C13H18N2O

: 108-91-8
cyclohexylamine

A: C15H20N2O

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
In [D3]acetonitrile at 25℃; Equilibrium constant; Molecular sieve;	A 100% B n/a

...Expand

: C12H18N2O2S

: 108-91-8
cyclohexylamine

A: C14H20N2O2S

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
In [D3]acetonitrile at 25℃; Equilibrium constant; Molecular sieve;	A 100% B n/a

...Expand

: 109-74-0
propyl cyanide

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With sodium tetrahydroborate In water; dimethyl sulfoxide at 60℃; for 4.5h; High pressure; Green chemistry;	99.9%
With sodium tetrahydroborate; nickel; sodium hydroxide In methanol; water at 30 - 60℃;	93%
With [DBUH(+)][C4H9COO(-)]; water; potassium formate at 70℃; for 3h; Ionic liquid;	82%

: 627-05-4
1-nitrobutane

12percent nickel/Al-SBA-15 fiber: 12percent nickel/Al-SBA-15 fiber

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With hydrogen In ethanol at 109.84℃; under 18751.9 Torr; for 7.5h; Autoclave; Green chemistry; chemoselective reaction;	99%

: 71-36-3
butan-1-ol

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With ammonia; hydrogen at 200℃; under 3750.38 Torr; Reagent/catalyst; Temperature; Pressure;	97.7%
With ammonia; nickel at 200℃;
With ammonia at 350 - 400℃; als Katalysatoren, eignen sich Cr2O3,NiO und SiO2 auf Al2O3;

: 123-72-8
butyraldehyde

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With ammonia; hydrogen In methanol at 30℃; for 15h; Autoclave;	96%
With ammonium hydroxide; Ni6AlO(z); hydrogen at 80℃; under 2250.23 Torr; for 3h; Autoclave;	83%
With (S)-1-phenyl-ethylamine; pyridoxal 5'-phosphate; pQR1108 In aq. phosphate buffer; dimethyl sulfoxide at 30℃; for 18h; pH=8; Enzymatic reaction;	42%

: 627-05-4
1-nitrobutane

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
Stage #1: 1-nitrobutane In water; acetonitrile at 20℃; for 0.0833333h; Stage #2: With sodium tetrahydroborate In water; acetonitrile at 20℃; for 0.333333h;	95%
Stage #1: 1-nitrobutane In water at 20℃; for 0.0166667h; Stage #2: With sodium tetrahydroborate In water at 50℃; for 0.166667h;	93%
With triethylamine In water at 80℃; for 6h; Inert atmosphere; Green chemistry; chemoselective reaction;	91%

: 1792-17-2
N,N'-di-n-butylurea

: 18522-92-4
sodium p-toluenesulfonamide

A: 64-77-7
N-[(butylamino)carbonyl]-4-methyl-benzenesulfonamide

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
at 150℃; for 8h; Product distribution; other time;;	A 94.5% B n/a
at 150℃; for 5h;	A 94.5% B n/a

...Expand

: 71-36-3
butan-1-ol

A: 109-74-0
propyl cyanide

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With ammonia; zinc(II) oxide at 420℃;	A 92.2% B n/a
With ammonia; zinc(II) oxide at 340℃; Product distribution; 1:4 molar ratio n-butyl alcohol/NH3, other temperature (300-420 deg C), other catalyst (oxidized form of SMS-4 Zn-Cr-O);;	A 86.7% B 6%

butyraldehyde oxime: 110-69-0
butyraldehyde oxime

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With sodium tetrahydroborate; nickel; sodium hydroxide In methanol; water at 20 - 30℃;	90%
With nickel at 80 - 105℃; Hydrogenation;
With lithium aluminium tetrahydride; diethyl ether
With ethanol; aluminium amalgam
With sodium n-propoxide In propan-1-ol at 69.84℃; for 2h; Reagent/catalyst;	98 %Chromat.

: 109-65-9
1-bromo-butane

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With 5-methyl-1,3,4-thiadiazol-2-amine; triethylamine In ethanol; water at 25℃; for 1h;	89%
With copper(ll) sulfate pentahydrate; ammonium hydroxide In PEG1000-DIL; methyl cyclohexane at 75℃; for 10h;	85%
With 2-methoxy-ethanol; sodium tetraamidoalanate In benzene at 50℃; for 6h; Product distribution; further educt/reagent ratios, temperatures, reaction times;	57%

: 59255-58-2
tert-butyl butylcarbamate

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With water at 100℃; for 13h;	87%

: 2403-22-7
N-Benzyl-N-butylamine

A: 100-52-7
benzaldehyde

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With dipotassium peroxodisulfate; tris(2,2'-bipyridyl)ruthenium dichloride In water; acetonitrile at 20℃; for 12h; Irradiation;	A 87% B n/a

: 1907-65-9
N-butyl-4-toluenesulfonamide

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With cesium fluoride supported on Celite at 120℃; for 2.5h; chemoselective reaction;	86%

: 1119-46-6
5-chloro-valeric acid

A: 110-89-4
piperidine

B: 675-20-7
piperidin-2-one

C: 110-58-7
1-pentanamine

D: 109-73-9
N-butylamine

Conditions

Conditions	Yield
Stage #1: 5-chloro-valeric acid With cyclopentyl methyl ether; ammonia at 200℃; under 4500.45 Torr; Sealed tube; Green chemistry; Stage #2: With cyclopentyl methyl ether; ammonia; hydrogen at 200℃; under 42004.2 Torr; for 6.5h; Cooling with ice; Green chemistry;	A 85% B 9% C 2% D 2%

...Expand

: 109-69-3
n-Butyl chloride

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With copper(ll) sulfate pentahydrate; ammonium hydroxide In PEG1000-DIL; methyl cyclohexane at 75℃; for 10h;	84%
With dibutyl ether; ammonia; water at 175℃;
With ammonia; water at 170℃;
With ammonia; water; dibutylamine at 175℃;
With tributyl-amine; ammonia; water at 175℃;

: 107-92-6
butyric acid

A: 541-35-5
butanamide

B: 10264-16-1
N-butyl-butyramide

C: 111-92-2
dibutylamine

D: 109-73-9
N-butylamine

Conditions

Conditions	Yield
Stage #1: butyric acid With cyclopentyl methyl ether; ammonia at 200℃; under 4500.45 Torr; Sealed tube; Green chemistry; Stage #2: With cyclopentyl methyl ether; ammonia; hydrogen at 200℃; under 42004.2 Torr; for 6.5h; Cooling with ice; Green chemistry;	A 6% B n/a C 5% D 80%

...Expand

: 52518-95-3
CuCl2(C4H9NH2)2

: bis(carbomethoxy)palladium bipyridine

: 14871-92-2
dichloro(2,2'-bipyridine)palladium(II)

B: 39583-95-4
CuCl(bipyridine)

C: 2594-21-0
methyl N-butylcarbamate

D: 3858-78-4
n-butylamine hydrochloride

E: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With nitrogen In tetrahydrofuran byproducts: CuCl; Pd-compd. in THF and CuCl2(BuNH2)2 in a Cu/Pd molar ratio of 4:1 are loaded sep. in the 2 branches of an inverted-Y glass reactor. Reactor is closed under N2, contents are mixed and stirred for 1 h.; IR, GC-MS and GLC anal. of liq. phase shows presence of BuNH2COOCH3. Filtn. of solid residue (anaerobic conditions), sepn. of PdCl2(bipy) from CuCl by addn. of MeOH soln. contg. bipy, IR, elem. anal. Removal of MeOH(vac.) gives CuCl(bipy). Elem. anal.;	A n/a B n/a C 79% D n/a E n/a

Yield

With nitrogen In tetrahydrofuran byproducts: CuCl; Pd-compd. in THF and CuCl2(BuNH2)2 in a Cu/Pd molar ratio of 4:1 are loaded sep. in the 2 branches of an inverted-Y glass reactor. Reactor is closed under N2, contents are mixed and stirred for 1 h.; IR, GC-MS and GLC anal. of liq. phase shows presence of BuNH2COOCH3. Filtn. of solid residue (anaerobic conditions), sepn. of PdCl2(bipy) from CuCl by addn. of MeOH soln. contg. bipy, IR, elem. anal. Removal of MeOH(vac.) gives CuCl(bipy). Elem. anal.;

A n/a
B n/a
C 79%
D n/a
E n/a

...Expand

: 81539-78-8
C28H38N4O5

A: 43113-25-3
2,2'-diphthalimido-diethyl ether

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
at 250℃;	A 62% B 75%

: 24473-71-0
{(n-C4H9NH2)2BH2}{SC2H5}

A: 1087352-20-2
tert-butylamine borane complex

B: 2080-01-5
N,N',N''-tri-n-butylborazine

C: 2387-02-2
HB(NH-n-C4H9)2

D: 109-73-9
N-butylamine

E: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In not given byproducts: H2; thermal decomposition between 40 and 50°C;;	A 33% B 15% C 15% D n/a E 75%
In not given

...Expand

: 125908-37-4
1-butyl-6-tolyl-2,5-dithiobiurea

A: 14731-25-0
2-(4'-methylphenylamino)-Δ2-1,3,4-thiadiazoline-5-thione

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With sodium hydroxide In water Heating;	A 74% B n/a

: 2834-31-3
1-butyl-6-phenyl-2,5-dithiobiurea

A: 109-73-9
N-butylamine

B: 10253-83-5
5-phenylamino-3H-[1,3,4]thiadiazole-2-thione

Conditions

Conditions	Yield
With sodium hydroxide In water Heating;	A n/a B 73%

: 872-50-4
1-methyl-pyrrolidin-2-one

: 1336-21-6
ammonium hydroxide

: 109-74-0
propyl cyanide

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
In methanol	73%

...Expand

: 55756-14-4
butyl-N,N-diformylamine

: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With hydrogenchloride In water for 2h; Heating;	72%

: 125908-43-2
1-butyl-6-(4'-ethoxyphenyl)-2,5-dithiobiurea

A: 68161-60-4
2-(4'-ethoxyphenylamino)-Δ2-1,3,4-thiadiazoline-5-thione

B: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With sodium hydroxide In water Heating;	A 72% B n/a

: 110-63-4
Butane-1,4-diol

A: 123-75-1
pyrrolidine

B: 767-10-2
1-butylpyrrolidine

C: 93264-47-2
4-(pyrrolidin-1-yl)butan-1-ol

D: 41726-75-4
1,4-di-(1-pyrrolidinyl)butane

E: 109-73-9
N-butylamine

Conditions

Conditions	Yield
With ammonia; hydrogen; iron RFC at 260℃; Product distribution; Mechanism; other temp. (280, 300, 310 deg C);	A 71% B 12% C n/a D n/a E 9%

...Expand

: 85-44-9
phthalic anhydride

: 109-73-9
N-butylamine

: 1515-72-6
N-butylphthalimide

Conditions

Conditions	Yield
for 0.0333333h; microwave irradiation;	100%
In decaethylene glycol at 120℃; for 6h;	98%
In water at 90 - 180℃; for 0.8h; Inert atmosphere;	96.2%

: 4548-45-2
2-chloro-5-nitropyridine

: 109-73-9
N-butylamine

: 26820-54-2
N-(5-nitropyridin-2-yl)butylamine

Conditions

Conditions	Yield
In dimethyl sulfoxide at 25℃;	100%
With ethanol
In methanol for 2h; Heating;
In dimethyl sulfoxide at 25℃; Kinetics;
In acetonitrile at 25℃; Kinetics; Further Variations:; amine concentration;

: 81-86-7
4-bromo-1,8-naphthalenedicarboxylic anhydride

: 109-73-9
N-butylamine

: 92874-17-4
4-bromo-N-butylnaphthalimide

Conditions

Conditions	Yield
In ethanol at 78℃; for 4h;	100%
In ethanol for 26h; Reflux;	100%
for 3h; Reflux;	94.5%

: 100-28-7
4-Nitrophenyl isocyanate

: 109-73-9
N-butylamine

: 21260-50-4
N-butyl-N'-(4'-nitrophenyl)urea

Conditions

Conditions	Yield
In 1,4-dioxane at 20℃; for 1h;	100%
In 1,4-dioxane at 20 - 40℃; for 3h;	100%
In 1,4-dioxane	96%

: 70-34-8
2,4-Dinitrofluorobenzene

: 109-73-9
N-butylamine

: 13059-86-4
2,4-dinitro-N-butylaniline

Conditions

Conditions	Yield
With 2-hydroxypyridin In benzene at 25℃; Rate constant; other catalysts, other solvents, var. conc. of catalysts;	100%
With 1-(1-butyl)-3-methylimidazolium tetrafluoroborate In acetonitrile at 25℃; Kinetics; Further Variations:; Reagents; Solvents;	100%
at 25℃; for 2h;	56%

: 100-52-7
benzaldehyde

: 109-73-9
N-butylamine

: 1077-18-5
N-benzylidenebutan-1-amine

Conditions

Conditions	Yield
With aluminum oxide for 5h; Milling;	100%
at 20℃; for 2h;	100%
With HC(CMeN(2,6-Et2C6H3)2)Al(μ-S)2AlHC(CMeN(2,6-Et2C6H3))2 In chloroform-d1 at 20℃; for 2h; Inert atmosphere;	99%

: 103-71-9
phenyl isocyanate

: 109-73-9
N-butylamine

: 3083-88-3
N-butyl-N'-phenylurea

Conditions

Conditions	Yield
Stage #1: phenyl isocyanate; N-butylamine In dichloromethane at 60℃; Stage #2: With isatoic anhydride-N-(CH2)3-C8F17 In dichloromethane at 60℃; for 2.5h;	100%
at 20℃;	98%
In hexane at 25℃; Cooling with ice;	98%

: 116-81-4
1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid

: 109-73-9
N-butylamine

: 101139-67-7
1-amino-4-(butylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate; copper(II) sulfate; iron(II) sulfate In water at 70 - 90℃; for 4h;	100%
With copper(I) sulfate; water; sodium carbonate; copper(II) sulfate at 80 - 90℃;

: 109-73-9
N-butylamine

: 598-21-0
2-Bromoacetyl bromide

: 67056-04-6
2-bromo-N-butylacetamide

Conditions

Conditions	Yield
With potassium carbonate In dichloromethane; water at 0 - 20℃; for 6.5h;	100%
In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;	96%
With potassium carbonate In dichloromethane; water at 0 - 20℃; for 12.5h;	95%

: 109-73-9
N-butylamine

: 140-88-5
ethyl acrylate

: 10494-81-2
ethyl N-(n-butyl)-b-aminopropionate

Conditions

Conditions	Yield
In ethanol at 20℃; for 2h; Michael addition;	100%
With poly(ethylene glycol) 2000; ruthenium trichloride at 50℃; for 8h; aza-Michael addition;	96%
Stage #1: N-butylamine With cerous nitrate for 4h; Reflux; Stage #2: ethyl acrylate for 8h; Time;	93.8%

: 109-73-9
N-butylamine

: 610-14-0
2-nitrobenzyl chloride

: 79903-04-1
N-butyl-2-nitrobenzamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0℃; for 1h;	100%
With sodium hydroxide

: 109-73-9
N-butylamine

: 762-04-9
phosphonic acid diethyl ester

: 20465-03-6
diethyl N-butylphosphoramidate

Conditions

Conditions	Yield
With potassium carbonate; potassium hydrogencarbonate; tetrabutylammomium bromide In tetrachloromethane; dichloromethane at 15 - 20℃; for 2h;	100%
With copper(ll) bromide In ethyl acetate at 25℃; for 3h;	92%
Stage #1: phosphonic acid diethyl ester With pyridine In acetonitrile Stage #2: N-butylamine With iodine In acetonitrile for 0.0833333h;	85%
In tetrachloromethane; xylene

: 5470-18-8
2-Chloro-3-nitropyridine

: 109-73-9
N-butylamine

: 26820-68-8
N-(3-nitropyridin-2-yl)butylamine

Conditions

Conditions	Yield
In dimethyl sulfoxide at 25℃;	100%
In methanol for 2h; Heating;
With potassium carbonate
In dimethyl sulfoxide at 25℃; Kinetics;
In acetonitrile at 25℃; Kinetics; Further Variations:; amine concentration;

: 459-57-4
4-fluorobenzaldehyde

: 109-73-9
N-butylamine

: (E)-N-(4-fluorobenzylidene)butan-1-amine

Conditions

Conditions	Yield
In benzene at 80℃; for 2h;	100%
In neat (no solvent) at 60℃; for 0.0666667h; Microwave irradiation;	98%
In diethyl ether Ambient temperature;	87%

: 64-19-7
acetic acid

: 109-73-9
N-butylamine

: 1119-49-9
N-butylacetamide

Conditions

Conditions	Yield
zirconium(IV) oxide at 200℃; Product distribution; the liquid- and vapor-phase amidation were investigated with different heterogeneous catalysts;	100%
zirconium(IV) oxide at 200℃;	100%
With (1-methyl-3-(3-sulfopropyl)-1H-imidazol-3-ium)3[PW12O403-] In neat (no solvent) at 100℃; for 0.0833333h; Green chemistry;	93%

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 109-73-9
N-butylamine

: 3717-82-6
N2-n-butyl-N1,N1-dimethylformamidine

Conditions

Conditions	Yield
at 60℃;	100%

: 141-78-6
ethyl acetate

: 109-73-9
N-butylamine

: 1119-49-9
N-butylacetamide

Conditions

Conditions	Yield
zirconium(IV) oxide at 200℃;	100%
With tin(IV) oxide at 200℃; further conditions: liquid phase, reflux;	79%
With aluminum oxide; monoaluminum phosphate at 77℃;	75%
With potassium tert-butylate at 95℃; for 0.05h; microwave irradiation;	70%

: 105-54-4
butanoic acid ethyl ester

: 109-73-9
N-butylamine

: 10264-16-1
N-butyl-butyramide

Conditions

Conditions	Yield
at 40℃; for 1h; lipase SP 382 (from Candida sp.);	100%
Stage #1: N-butylamine With TurboGrignard In tetrahydrofuran at 20℃; for 0.1h; Microreactor; Stage #2: butanoic acid ethyl ester In tetrahydrofuran at 20℃; for 0.233333h; Bodroux reaction; Microreactor;	82%

: 89-60-1
1-chloro-4-methyl-2-nitro-benzene

: 109-73-9
N-butylamine

: 216591-86-5
N-butyl-4-methyl-2-nitroaniline

Conditions

Conditions	Yield
at 92℃; for 96h; Inert atmosphere;	100%
for 3.5h; Heating;

: 4504-12-5
ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxaldehyde

: 109-73-9
N-butylamine

: 146848-35-3
N,N'-dibutyl-N''-phenylmethanetricarboxamide

Conditions

Conditions	Yield
In acetone at 25℃;	100%
Irradiation; silica glass;	80%
In acetone at 20℃; for 0.25h; Irradiation;	37%

: 67-56-1
methanol

: 109-73-9
N-butylamine

: 927-62-8
N,N-dimethylbutylamine

Conditions

Conditions	Yield
chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium (II) at 100℃;	100%
With Diethyl phosphonate Rate constant; Ambient temperature;
at 150℃; under 7500.75 Torr;

: 116-16-5
1,1,1,3,3,3-hexachloro-propan-2-one

: 109-73-9
N-butylamine

A: 67-66-3
chloroform

B: 31464-96-7
trichloro-acetic acid butylamide

Conditions

Conditions	Yield
In hexane	A n/a B 100%

...Expand

: 32837-88-0
4-hydroxy-4-methylhex-2-ynenitrile

: 109-73-9
N-butylamine

: 134965-70-1
4-[(E)-Butylimino]-5-ethyl-5-methyl-4,5-dihydro-furan-2-ylamine

Conditions

Conditions	Yield
In dichloromethane at 40℃; for 24h;	100%

: 605-65-2
5-(dimethylamino)naphth-1-ylsulfonyl chloride

: 109-73-9
N-butylamine

: 55032-39-8
(N,N-dimethylamino)-naphthalene-N-butyl-1-sulfonamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; for 3.5h; Inert atmosphere;	100%
	90%
With triethylamine In dichloromethane at 0 - 20℃; for 3h; Inert atmosphere;	88%

: 7468-67-9
o-formylbenzonitrile

: 109-73-9
N-butylamine

: 93680-02-5
3-(butylamino)isoindolin-1-one

Conditions

Conditions	Yield
at 20℃; for 6h;	100%
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile at 20℃; Electrolysis;	85%

Butylamine Specification

The Butylamine is an organic compound with the formula C₄H₁₁N. The IUPAC name of this chemical is butan-1-amine. With the CAS registry number 109-73-9, it is also named as 1-Amino-butaan. The product's categories are Pharmaceutical Intermediates; Anilines, Aromatic Amines and Nitro Compounds; Alkylamines; Monofunctional & alpha,omega-Bifunctional Alkanes; Monofunctional Alkanes. Besides, it is colourless to yellow liquid, which should be stored in a cool and well-ventilated place. It is used as an ingredient in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifiers. It is also a precursor for the manufacture of N,N'-dibutylthiourea, a rubber vulcanization accelerator, and n-butylbenzenesulfonamide, a plasticizer of nylon.

Physical properties about Butylamine are: (1)ACD/LogP: 0.93; (2)ACD/LogD (pH 5.5): -2.17; (3)ACD/LogD (pH 7.4): -1.95; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 1; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Polar Surface Area: 3.24 Å²; (12)Index of Refraction: 1.405; (13)Molar Refractivity: 24.11 cm³; (14)Molar Volume: 98.2 cm³; (15)Polarizability: 9.56×10^-24cm³; (16)Surface Tension: 25.3 dyne/cm; (17)Density: 0.744 g/cm³; (18)Flash Point: °C; (19)Enthalpy of Vaporization: 31.81 kJ/mol; (20)Boiling Point: 77.3 °C at 760 mmHg; (21)Vapour Pressure: 97.3 mmHg at 25°C.

Preparation of Butylamine: Butylamine can be prepared by butanol vapor and ammonia . This reaction will need catalyst alumina and molybdenum oxide.

Uses of Butylamine: it can be used to produce N,N'-dibutyl-acetamidine and 2,4,6-trimethyl-[1,3,5]triazine by heating. It will need reagent Ln(CF₃SO₃)₃ with reaction time of 18 hours. The yield is about 4.7%.

When you are using Butylamine, please be cautious about it as the following:
The Butylamine is highly flammable and harmful by inhalation, in contact with skin and if swallowed. Please keep away from sources of ignition - No smoking. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical can cause severe burns. When you are using it, wear suitable gloves and eye/face protection and do not empty into drains. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: NCCCC
(2)InChI: InChI=1/C4H11N/c1-2-3-4-5/h2-5H2,1H3
(3)InChIKey: HQABUPZFAYXKJW-UHFFFAOYAE
(4)Std. InChI: InChI=1S/C4H11N/c1-2-3-4-5/h2-5H2,1H3
(5)Std. InChIKey: HQABUPZFAYXKJW-UHFFFAOYSA-N

The toxicity data of Butylamine is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	430mg/kg (430mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 40(11), Pg. 21, 1975.
guinea pig	LD50	skin	500uL/kg (0.5mL/kg)		Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944.
mammal (species unspecified)	LD50	unreported	590mg/kg (590mg/kg)		Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mouse	LC50	inhalation	800mg/m³/2H (800mg/m³)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 28, 1982.
mouse	LD50	intraperitoneal	629mg/kg (629mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 82, 1946.
mouse	LD50	intravenous	198mg/kg (198mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 82, 1946.
mouse	LD50	oral	430mg/kg (430mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 40(11), Pg. 21, 1975.
rabbit	LD50	skin	850uL/kg (0.85mL/kg)		Union Carbide Data Sheet. Vol. 7/19/1965,
rat	LCLo	inhalation	4000ppm/4H (4000ppm)		Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 343, 1949.
rat	LD50	oral	366mg/kg (366mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Toxicology and Applied Pharmacology. Vol. 63, Pg. 150, 1982.
rat	LDLo	parenteral	600mg/kg (600mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 20, Pg. 435, 1923.

Product Name

Butylamine

Synthetic route

Butylamine Specification

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