Cyclopropylamine supplier | CasNO.765-30-0

Name
Cyclopropylamine
EINECS 212-142-2
CAS No. 765-30-0
Article Data40
CAS DataBase
Density 0.938 g/cm³
Solubility Miscible with water, ethanol,ether and chloroform.
Melting Point -50 °C
Formula C₃H₇N
Boiling Point 49.3 °C at 760 mmHg
Molecular Weight 57.0953
Flash Point -14 °F
Transport Information UN 2733 3/PG 2
Appearance Clear and colourless, volatile liquid
Safety 16-26-36/37/39-45-33-7/9
Risk Codes 11-22-34-36/37
Molecular Structure
Hazard Symbols F, C, Xi
Synonyms Cyclopropanamine;Aminocyclopropane;
PSA 26.02000
LogP 0.80780

Synthetic route

: 13021-02-8
nitrocyclopropane

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With triethylamine In water at 80℃; for 6h; Inert atmosphere; Green chemistry; chemoselective reaction;	91%
With hydrogenchloride; iron
With methanol; nickel Hydrogenation;

: 6228-73-5
Cyclopropancarbamid

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With sodium hydroxide; sodium hypochlorite; water at 31 - 103℃; Conversion of starting material; Hofmann Rearrangement; Heating / reflux;	62%
With bromine dann man behandelt mit Kalilauge und destilliert mit Wasserdampf;
zur Bildung;

: 73330-91-3
Methyl N-cyclopropylcarbamate

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With potassium hydroxide

(E)-1-cyclopropyl-ethanone oxime: (E)-1-cyclopropyl-ethanone oxime

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With 1,2-dimethoxyethane; trifluoroacetic anhydride und anschliessend mit KOH in wss. Aethylenglykol;

: 1759-53-1
cyclopropanecarboxylic acid

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With hydrogen azide; chloroform; sulfuric acid

: cyclopropanone oxime

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With sodium bis(2-methoxyethoxy)aluminium dihydride In toluene at 140℃; for 4h;

: 27374-25-0
[(1-Ethoxycyclopropyl)oxy]trimethylsilane

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With formic acid; C24H22N4BF4(1-)Ru(2+)Cl(1-)C10H14; ammonium formate In neat (no solvent) at 40℃; for 12h; Green chemistry; chemoselective reaction;

: diphenyl cyclopropylphosphoramidate

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
Stage #1: diphenyl cyclopropylphosphoramidate With water; monoammonium para-toluenesulfonate; o-phthalic dicarboxaldehyde In acetonitrile at 90℃; for 24h; Sealed tube; Stage #2: With sodium hydroxide In water pH=8 - 9; chemoselective reaction;

: N-cyclopropyl-P,P-diphenylphosphinic amide

: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
Stage #1: N-cyclopropyl-P,P-diphenylphosphinic amide With water; monoammonium para-toluenesulfonate; o-phthalic dicarboxaldehyde In acetonitrile at 90℃; for 24h; Sealed tube; Stage #2: With sodium hydroxide In water pH=8 - 9; chemoselective reaction;

: 3187-77-7
N-benzylidenecyclopropanamine

A: 100-52-7
benzaldehyde

B: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With 20 μM Tris pH 9.0 buffer at 25℃; Rate constant;

: Nα-cyclopropyltryptophan

A: 392-12-1
Indole-3-pyruvic acid

B: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
With sodium dithionite; tryptophan lyase (NosL) Y90A; S-Adenosyl-L-methionine In aq. phosphate buffer pH=7.5; Reagent/catalyst; Inert atmosphere; Enzymatic reaction;

: 13324-66-8
N-benzylcyclopropanamine

A: 100-52-7
benzaldehyde

B: 765-30-0
Cyclopropylamine

C: 100-46-9
benzylamine

Conditions

Conditions	Yield
With mitochondrial monoamine oxidase In water Mechanism; Product distribution; experiments with 14C- and 3H-labelled compounds; comparison of enzyme and electrochemical amine oxidation mechanism (two electron transfers via a radical cation intermediate);

...Expand

: 75-19-4
cyclopropane

A: 765-30-0
Cyclopropylamine

B H2, NH3, N2, N2H4: H2, NH3, N2, N2H4

Conditions

Conditions	Yield
With hydrogen azide at -72℃; Product distribution; Mechanism; Irradiation; other hydrocarbons; var. temp. and concentration of hydrogen azide;

: 60-29-7
diethyl ether

: 10026-13-8, 874483-75-7
phosphorus pentachloride

: 51761-72-9
cyclopropyl methyl ketone oxime

A: 74-89-5
methylamine

B: 765-30-0
Cyclopropylamine

Conditions

Conditions	Yield
Kochen des Reaktionsprodukts mit wss. KOH;

...Expand

: 6228-73-5
Cyclopropancarbamid

: 7726-95-6
bromine

KOH-solution: KOH-solution

: 765-30-0
Cyclopropylamine

...Expand

: 105-36-2
ethyl bromoacetate

: 765-30-0
Cyclopropylamine

: 71922-62-8
[(cyclopropyl)amino]acetic acid ethyl ester

Conditions

Conditions	Yield
In ethanol for 1h;	100%
With triethylamine In diethyl ether at 20℃;	100%
In ethanol at 0 - 20℃; for 18h;	99%

: 105-56-6
ethyl 2-cyanoacetate

: 765-30-0
Cyclopropylamine

: 15029-37-5
2-cyano-N-cyclopropylacetamide

Conditions

Conditions	Yield
at 45℃; for 1.5h;	100%
at 38℃; for 2.33333h;	91%
In ethanol at 20℃;	82%

: 79-04-9
chloroacetyl chloride

: 765-30-0
Cyclopropylamine

: 19047-31-5
2-chloro-N-cyclopropylacetamide

Conditions

Conditions	Yield
With potassium carbonate In dichloromethane at 20℃; for 2.16667h; Inert atmosphere; Reflux;	100%
In dichloromethane at 0℃; for 2h;	99%
In diethyl ether at 0℃;	97%

: 922-67-8
propynoic acid methyl ester

: 765-30-0
Cyclopropylamine

: 72396-25-9
3-(Cyclopropylamino)acrylsaeure-methylester

Conditions

Conditions	Yield
In 1,4-dioxane at 150℃; for 0.0166667h; Flow reactor; Inert atmosphere;	100%
In acetonitrile 1.) 1 h, 5 - 10 deg C, 2.) 5 h, room temperature.;	92%

: 24424-99-5
di-tert-butyl dicarbonate

: 765-30-0
Cyclopropylamine

: 132844-48-5
1,1-dimethylethyl cyclopropylcarbamate

Conditions

Conditions	Yield
In dichloromethane at 0 - 20℃; for 1h; Inert atmosphere;	100%
In dichloromethane at 25℃; for 2h;	99%
In dichloromethane at 0 - 20℃; for 18h;	99%

: 609-67-6
2-Iodobenzoyl chloride

: 765-30-0
Cyclopropylamine

: 88229-19-0
N-Cyclopropyl-2-iodo-benzamide

Conditions

Conditions	Yield
In benzene for 18h;	100%
Stage #1: 2-Iodobenzoyl chloride; Cyclopropylamine In tetrahydrofuran for 0.166667h; Inert atmosphere; Stage #2: With triethylamine In tetrahydrofuran at 20℃; for 16h; Inert atmosphere;

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 765-30-0
Cyclopropylamine

: 131775-91-2
<(Cyclopropylamino)methylene>propanedioic acid diethyl ester

Conditions

Conditions	Yield
In methanol at 0℃; for 0.25h;	100%
at 20℃; for 0.683333h; Cooling with ice;	100%
	98.1%
In ethanol at 320℃; for 0.5h;	98%
In acetonitrile at 20 - 80℃;

: 765-30-0
Cyclopropylamine

: 109-94-4
formic acid ethyl ester

: 58644-54-5
N-cyclopropylformamide

Conditions

Conditions	Yield
for 4h; Heating;	100%
at 50℃; for 5h;	84%
With sodium carbonate In ethanol for 20h; Ambient temperature;	59%

: 100-52-7
benzaldehyde

: 765-30-0
Cyclopropylamine

: 3187-77-7
N-benzylidenecyclopropanamine

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane at 20℃; for 18h;	100%
With magnesium sulfate In dichloromethane at 20℃; for 18h; Inert atmosphere;	100%
at 20℃; for 2h; neat (no solvent);	93%

: 765-30-0
Cyclopropylamine

: 210163-00-1
3-(6-chloro-9H-purin-9-yl)-1-N-[(N-tert-butyloxycarbonyl-O-carbobenzyloxy)amino]propane

: 210163-02-3
3-(6-cyclopropylamino-9H-purin-9-yl)-1-N-(N-tert-butyloxycarbonylhydroxamino)propane

Conditions

Conditions	Yield
In tetrahydrofuran for 24h; Ambient temperature;	100%

: 108-94-1
cyclohexanone

: 765-30-0
Cyclopropylamine

: 824-82-8
N-cyclopropylcyclohexylamine

Conditions

Conditions	Yield
Stage #1: cyclohexanone; Cyclopropylamine In ethanol at 20℃; for 18h; Stage #2: With hydrogen; palladium on activated charcoal at 20℃; under 2585.81 Torr; for 10h;	100%
With platinum(IV) oxide; hydrogen In ethanol at 20℃; under 760.051 Torr;	66%
With palladium on activated charcoal; hydrogen 1.) EtOH, 2.) EtOH; Yield given. Multistep reaction;

: 87-42-3
6-chloropurine

: 765-30-0
Cyclopropylamine

: 117761-02-1
6-(cyclopropylamino)-9H-purine

Conditions

Conditions	Yield
In ethanol for 6h; Heating;	100%
In isopropyl alcohol at 120℃; for 2h;	90%
In methanol	81.4%
In ethanol Heating;
In ethanol for 16h; Heating;

: 765-30-0
Cyclopropylamine

: 66441-23-4, 71283-80-2
fenoxaprop-p-ethyl

A: (6-Chloro-benzooxazol-2-yl)-cyclopropyl-amine

B: 71301-98-9
(R)-2-(4-hydroxyphenoxy)propionic acid ethyl ester

Conditions

Conditions	Yield
at 20℃;	A 100% B n/a

...Expand

: 98760-08-8, 98818-34-9, 98818-35-0, 103127-56-6, 98737-29-2
(1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester

: 765-30-0
Cyclopropylamine

: 695215-98-6
(1S,2R)-(1-benzyl-3-cyclopropylamino-2-hydroxypropyl)carbamic acid tert-butyl ester

Conditions

Conditions	Yield
In isopropyl alcohol at 50℃; for 16h;	100%
In isopropyl alcohol at 50℃; for 7h;	99%
In acetonitrile at 80℃; for 10h;	91.4%

: 765-30-0
Cyclopropylamine

: 1489-69-6
Cyclopropanecarboxaldehyde

: Cyclopropyl-[1-cyclopropyl-meth-(E)-ylidene]-amine

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane Heating;	100%

: 51317-66-9
4-(4-isothiocyanato-phenyl)morpholine

: 765-30-0
Cyclopropylamine

: 903671-54-5
N-cyclopropyl-N'-[4-(4-morpholinyl)phenyl]thiourea

Conditions

Conditions	Yield
In ethyl acetate at 20℃; for 5.16667h;	100%

: 765-30-0
Cyclopropylamine

: 516479-35-9
(Z)-ethyl 3-ethoxy-2-(2,3,4,5,6-pentafluorobenzoyl)acrylate

: ethyl 2-(pentafluorobenzoyl)-3-cyclopropylaminoacrylate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 1.5h;	100%

: 960371-45-3
4-(hydroxymethyl)-4-(pyrimidin-2-yl)cyclohexanone

: 765-30-0
Cyclopropylamine

: 960371-46-4
(4-(cyclopropylamino)-1-(pyrimidin-2-yl)cyclohexyl)methanol

Conditions

Conditions	Yield
Stage #1: 4-(hydroxymethyl)-4-(pyrimidin-2-yl)cyclohexanone; Cyclopropylamine With sodium tris(acetoxy)borohydride; acetic acid In acetonitrile at 0 - 25℃; for 20h; Stage #2: With sodium hydroxide; water In acetonitrile pH=~ 12;	100%

: 960371-48-6
C12H14N2O3

: 765-30-0
Cyclopropylamine

: 960371-49-7
C15H21N3O2

Conditions

Conditions	Yield
Stage #1: C12H14N2O3; Cyclopropylamine With sodium tris(acetoxy)borohydride; acetic acid In acetonitrile at 0 - 25℃; for 3h; Stage #2: With sodium hydroxide; water In acetonitrile	100%

: 4755-77-5
Ethyl oxalyl chloride

: 765-30-0
Cyclopropylamine

: 722486-66-0
2-(cyclopropylamino)-2-oxoacetic acid ethyl ester

Conditions

Conditions	Yield
With triethylamine In diethyl ether at 0 - 20℃; for 1h;	100%
Stage #1: Ethyl oxalyl chloride With pyridine In dichloromethane at 0℃; for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: Cyclopropylamine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere; Schlenk technique;	93%
With triethylamine In tetrahydrofuran at 0℃; for 0.166667h;	78%

: 872-85-5
pyridine-4-carbaldehyde

: 765-30-0
Cyclopropylamine

: 165806-97-3
pyridine-4-carboxaldehyde cyclopropylimine

Conditions

Conditions	Yield
With magnesium sulfate	100%

: 663611-49-2
methyl 4-(2,5-dichloropyrimidin-4-yl)benzoate

: 765-30-0
Cyclopropylamine

: 4-(5-chloro-2-cyclopropylaminopyrimidin-4-yl)benzoic acid methyl ester

Conditions

Conditions	Yield
In ethanol at 80℃;	100%

: (Z)-4-(2-methoxybenzylidene)-2-(4-nitrophenyl)oxazol-5(4H)-one

: 765-30-0
Cyclopropylamine

: N-[cyclopropylcarbamoyl-2-(2-methoxy-phenyl)-vinyl]-4-nitro-benzamide

Conditions

Conditions	Yield
at 20℃; for 4h;	100%

: 2458-12-0
3-amino-p-toluic acid

: 2592-95-2
benzotriazol-1-ol

: 765-30-0
Cyclopropylamine

: 623155-19-1
3-amino-N-cyclopropyl-4-methylbenzamide

Conditions

Conditions	Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; DMF (N,N-dimethyl-formamide) at 54℃; for 1.83333h;	100%

...Expand

: 765-30-0
Cyclopropylamine

: 205756-65-6
4,6-dichloro-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one

: 656260-84-3
C11H10ClF3N2

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 1h;	100%

: 2458-12-0
3-amino-p-toluic acid

: 765-30-0
Cyclopropylamine

: 623155-19-1
3-amino-N-cyclopropyl-4-methylbenzamide

Conditions

Conditions	Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap In N,N-dimethyl-formamide at 0 - 20℃;	100%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃;	100%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In DMF (N,N-dimethyl-formamide) at 20℃;	72%
With dmap In water; ethyl acetate; N,N-dimethyl-formamide	72%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃;

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 765-30-0
Cyclopropylamine

: 400839-43-2
N-cyclopropyl-2-nitrobenzenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	100%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 15h; Inert atmosphere;	93%
With triethylamine In tetrahydrofuran at 0℃; for 1h;	87%

: 31872-62-5
4-methoxy-3-nitro-pyridine

: 765-30-0
Cyclopropylamine

: 380605-28-7
N-cyclopropyl-3-nitropyridin-4-amine

Conditions

Conditions	Yield
at 100℃; Sealed tube; Inert atmosphere;	100%
With N-ethyl-N,N-diisopropylamine In ethanol for 3h; Reflux;	72%
With N-ethyl-N,N-diisopropylamine In ethanol for 3h; Reflux;	72%

: 56826-69-8
5,6,7,8-Tetrahydroquinolin-8-one

: 765-30-0
Cyclopropylamine

: 878025-82-2
N-cyclopropyl-5,6,7,8-tetrahydro-8-quinolinamine

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; acetic acid In 1,1-dichloroethane at 20℃; for 17h;	100%

: 881677-89-0
3-[(4-{[(tert-butoxycarbonyl)(methyl)amino]methyl}-2-phenyl-1H-pyrrol-1-yl)sulfonyl]benzoic acid

: 765-30-0
Cyclopropylamine

: 881677-97-0
tert-butyl {[1-({3-[(cyclopropylamino)carbonyl]phenyl}sulfonyl)-5-phenyl-1H-pyrrol-3-yl]methyl}methylcarbamate

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 0.5h;	100%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 10 - 35℃; for 0.5h;	100%

Cyclopropylamine Chemical Properties

Cyclopropylamine is the chemical compound with the formula C₃H₇N.Its molar weight is 57.09.
Cyclopropylamine chemical structural formula is .
Synonyms Aminocyclopropane
CAS Registry Number 765-30-0
EINECS 212-142-2
Density 0.824
Melting point -50 ^oC
Boiling point 49-50 ^oC
Refractive index 1.419-1.422
Flash point 1 ^oC
Refractive index : n20/D 1.420(lit.)
Storage temp : Flammables area

Cyclopropylamine Safety Profile

A very dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NO_x. Hazard Symbols : F C
The Risk Statements information of Cyclopropylamine R11:Highly flammable;R22:Harmful if swallowed.;R34:Causes burns;
The Safety Statements information of Cyclopropylamine S16:Keep away from sources of ignition - No smoking.
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection;
S45:In case of accident of if you feel unwell, seek medical advice immediately (show the label where possible).

Product Name

Cyclopropylamine

Synthetic route

Cyclopropylamine Chemical Properties

Cyclopropylamine Safety Profile

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