Product Name

  • Name

    2,2-Dichloroacetyl chloride

  • EINECS 201-199-9
  • CAS No. 79-36-7
  • Article Data86
  • CAS DataBase
  • Density 1.581 g/cm3
  • Solubility may decompose in water
  • Melting Point < 25oC
  • Formula C2HCl3O
  • Boiling Point 107.5 °C at 760 mmHg
  • Molecular Weight 147.388
  • Flash Point 31.8 °C
  • Transport Information UN 1765 8/PG 2
  • Appearance colourless to light yellow fuming liquid
  • Safety 9-26-45-61
  • Risk Codes 35-50
  • Molecular Structure Molecular Structure of 79-36-7 (2,2-Dichloroacetyl chloride)
  • Hazard Symbols CorrosiveC, DangerousN
  • Synonyms Acetylchloride, dichloro- (6CI,7CI,8CI,9CI);Dichloracetyl chloride;Dichloroaceticacid chloride;Dichloroethanoyl chloride;a,a-Dichloroacetylchloride;Acetylchloride, 2,2-dichloro-;
  • PSA 17.07000
  • LogP 1.55550

Synthetic route

Trichloroethylene
79-01-6

Trichloroethylene

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With tributyl borane; oxygen at 80℃; under 2280.15 Torr; for 11h; Reagent/catalyst;90%
With oxygen; chlorine at 40 - 50℃; Irradiation.im UV-Licht;
With oxygen Irradiation.beim Behandeln des erhaltenen Gemisches aus Dichloracetylchlorid und Trichloraethylenoxyd mit wenig Dimethylamin oder anderen sekundaeren oder tertiaeren Aminen;
ethylphenylphosphinous chloride
15849-83-9, 75231-38-8, 75231-39-9

ethylphenylphosphinous chloride

trichloroacetic acid
76-03-9

trichloroacetic acid

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

ethylphenylphosphinic chloride
1499-22-5

ethylphenylphosphinic chloride

Conditions
ConditionsYield
for 1h; Ambient temperature; argon atmosphere;A 88%
B 50%
Ambient temperature;A 88%
B 50%
diethylchlorophosphine
686-69-1

diethylchlorophosphine

trichloroacetic acid
76-03-9

trichloroacetic acid

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

diethylphosphinic chloride
1112-37-4

diethylphosphinic chloride

Conditions
ConditionsYield
for 1h; Ambient temperature;A 87%
B 60%
ethyl ester of ethylphenylthiophosphinic acid
6587-98-0, 62621-04-9, 62621-07-2

ethyl ester of ethylphenylthiophosphinic acid

trichloroacetic acid
76-03-9

trichloroacetic acid

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

S-ethyl dichlorothiolacetate
41880-03-9

S-ethyl dichlorothiolacetate

C

ethylphenylphosphinic chloride
1499-22-5

ethylphenylphosphinic chloride

D

S-ethyl ethylphenylphosphinothioate
33626-88-9

S-ethyl ethylphenylphosphinothioate

Conditions
ConditionsYield
for 1h; Ambient temperature; argon atmosphere;A 64%
B 60%
C n/a
D n/a
2-chloropropionyl chloride
7623-09-8

2-chloropropionyl chloride

tropone azine
86428-01-5

tropone azine

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

3,3'-Dimethyl-[1,1']bi[cyclohepta[b]pyrrolyl]-2,2'-dione

3,3'-Dimethyl-[1,1']bi[cyclohepta[b]pyrrolyl]-2,2'-dione

C

3-Chloro-3,3'-dimethyl-3,3a-dihydro-[1,1']bi[cyclohepta[b]pyrrolyl]-2,2'-dione

3-Chloro-3,3'-dimethyl-3,3a-dihydro-[1,1']bi[cyclohepta[b]pyrrolyl]-2,2'-dione

Conditions
ConditionsYield
With triethylamine In dichloromethane at 40℃; for 21h;A 9%
B 22%
C 38%
dichloro-acetic acid
79-43-6

dichloro-acetic acid

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
Stage #1: dichloro-acetic acid With chloroform; oxygen; N,N-dimethyl-formamide at 30℃; for 3h; Irradiation;
Stage #2: at 30℃; for 2h;
7%
With thionyl chloride
With zinc(II) chloride; phosphorus trichloride
Ketene
463-51-4

Ketene

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With dichloromethane; chlorine at -50℃;
Ketene
463-51-4

Ketene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

chloroacetyl chloride
79-04-9

chloroacetyl chloride

Conditions
ConditionsYield
With chlorine in der Gasphase;
phosgene
75-44-5

phosgene

dichloro-acetic acid
79-43-6

dichloro-acetic acid

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With anionenexchanger at 130℃;
Trichloroethylene
79-01-6

Trichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

chloral
75-87-6

chloral

Conditions
ConditionsYield
With oxygen Umsetzung der bis 107grad siedenden Anteile des Reaktionsprodukts mit Metallchloriden wie SbCl5,FeCl3 oder AlCl3;
pentachloroethane
76-01-7

pentachloroethane

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With sulfuric acid at 50 - 60℃;
2,2-dichloroacetaldehyde
79-02-7

2,2-dichloroacetaldehyde

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With chlorine mit Hilfe von UV-Licht;
With acetyl-cyclohexanesulfonyl peroxide; chlorine
(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With chlorine
dichloro-acetic acid
79-43-6

dichloro-acetic acid

Benzotrichlorid
98-07-7

Benzotrichlorid

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

benzoyl chloride
98-88-4

benzoyl chloride

Conditions
ConditionsYield
With zinc(II) chloride at 120℃;
With zinc(II) chloride at 120℃;
Ketene
463-51-4

Ketene

chloroacetyl chloride
79-04-9

chloroacetyl chloride

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With chlorine at -18℃;
chloroacetyl chloride
79-04-9

chloroacetyl chloride

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

Trichloroacetyl chloride
76-02-8

Trichloroacetyl chloride

Conditions
ConditionsYield
With pyridine; chlorine at 75 - 80℃;
Trichloroacetyl chloride
76-02-8

Trichloroacetyl chloride

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With quinoline; Pd-BaSO4; sulfur at 140℃; Reagens 4: Petroleum;
1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
With air Irradiation.bei 26-taegiger UV-Bestrahlung;
With oxygen Irradiation.bei 26-taegiger UV-Bestrahlung;
1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

1,1,1,2,2,3,3,4-octachloro-butane
88982-96-1

1,1,1,2,2,3,3,4-octachloro-butane

C

oxalic acid
144-62-7

oxalic acid

Conditions
ConditionsYield
bei 26-taegigem Bestrahlung mit UV-Licht unter Durchleiten von trockener Luft oder trockenem Sauerstoff.Irradiation;
trichloroethylene epoxide
16967-79-6

trichloroethylene epoxide

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Conditions
ConditionsYield
diethylamine at 60℃; for 1h; sealed tube; Yield given;
trichloroethylene epoxide
16967-79-6

trichloroethylene epoxide

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

chloral
75-87-6

chloral

Conditions
ConditionsYield
at 130℃; for 2h; Product distribution; Kinetics; Thermodynamic data; sealed tube, var.catalysts, oth. temperature, E(activ.);A 91 % Chromat.
B 9 % Chromat.
Conditions
ConditionsYield
With hydroxide In gas at 27.9℃; under 0.4 - 4.2 Torr; Product distribution; Thermodynamic data; Rate constant; other temperatures; A, E;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

trichloroethylene epoxide
16967-79-6

trichloroethylene epoxide

trans-1,2-Dichloroethylene epoxide
16650-12-7

trans-1,2-Dichloroethylene epoxide

D

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; for 56h; Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

dichloromethyl 1,2,2-trichloroethyl ether
117702-58-6

dichloromethyl 1,2,2-trichloroethyl ether

trans-1,2-Dichloroethylene epoxide
16650-12-7

trans-1,2-Dichloroethylene epoxide

D

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; for 56h; Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

1,2,2,2-tetrachloroethyl 1,2,2-trichloroethyl ether
117702-56-4

1,2,2,2-tetrachloroethyl 1,2,2-trichloroethyl ether

trans-1,2-Dichloroethylene epoxide
16650-12-7

trans-1,2-Dichloroethylene epoxide

D

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; for 56h; Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

1,2,2-trichloroethyl dichloroacetate
117702-57-5

1,2,2-trichloroethyl dichloroacetate

trans-1,2-Dichloroethylene epoxide
16650-12-7

trans-1,2-Dichloroethylene epoxide

D

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; for 56h; Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

meso-bis(1,2,2-trichloroethyl) ether
117702-53-1

meso-bis(1,2,2-trichloroethyl) ether

trans-1,2-Dichloroethylene epoxide
16650-12-7

trans-1,2-Dichloroethylene epoxide

D

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; for 56h; Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

rac-bis(1,2,2-trichloroethyl) ether
117702-53-1, 117702-54-2

rac-bis(1,2,2-trichloroethyl) ether

trans-1,2-Dichloroethylene epoxide
16650-12-7

trans-1,2-Dichloroethylene epoxide

D

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; for 56h; Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
trans-1,2-dichloroethylene
156-60-5

trans-1,2-dichloroethylene

A

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

B

pentachloroethane
76-01-7

pentachloroethane

C

2,2-dichloroacetaldehyde
79-02-7

2,2-dichloroacetaldehyde

D

meso-1,1,2,3,4,4-hexachloro-butane
32149-32-9

meso-1,1,2,3,4,4-hexachloro-butane

E

dichloromethyl 1,2,2-trichloroethyl ether
117702-58-6

dichloromethyl 1,2,2-trichloroethyl ether

F

1,1,2,2-tetrachloroethane
79-34-5

1,1,2,2-tetrachloroethane

Conditions
ConditionsYield
With oxygen; chlorine In neat (no solvent) at 30℃; under 1050.08 Torr; Mechanism; Rate constant; Product distribution; Irradiation;
Trichloroethylene
79-01-6

Trichloroethylene

A

dichloro-acetic acid
79-43-6

dichloro-acetic acid

B

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

C

1,1,3,3,4,4,-hexachloro-1-butene
34973-39-2

1,1,3,3,4,4,-hexachloro-1-butene

Conditions
ConditionsYield
In neat (no solvent) at 130℃; Product distribution; effect of the time and the temp.;
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

diethyl 2-[(4-methoxyphenyl)amino]malonate
24043-40-1

diethyl 2-[(4-methoxyphenyl)amino]malonate

2-[(2,2-Dichloro-acetyl)-(4-methoxy-phenyl)-amino]-malonic acid diethyl ester
106817-56-5

2-[(2,2-Dichloro-acetyl)-(4-methoxy-phenyl)-amino]-malonic acid diethyl ester

Conditions
ConditionsYield
In benzene for 2h; Heating;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Isopropylphenyl(trimethylsilyl)phosphan
29574-16-1

Isopropylphenyl(trimethylsilyl)phosphan

(Dichloracetyl)isopropylphenylphosphan
104192-61-2

(Dichloracetyl)isopropylphenylphosphan

Conditions
ConditionsYield
In diethyl ether at -80℃; for 5h;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Ethylphenyl(trimethylsilyl)phosphan
59877-22-4

Ethylphenyl(trimethylsilyl)phosphan

(Dichloracetyl)ethylphenylphosphan

(Dichloracetyl)ethylphenylphosphan

Conditions
ConditionsYield
In diethyl ether at -80℃; for 5h;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Phenyl-n-propyl(trimethylsilyl)phosphan
59877-23-5

Phenyl-n-propyl(trimethylsilyl)phosphan

(Dichloracetyl)phenyl-n-propylphosphan

(Dichloracetyl)phenyl-n-propylphosphan

Conditions
ConditionsYield
In diethyl ether at -80℃; for 5h;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

methyl (2E)-3-(2-aminophenyl)propenoate
88939-75-7

methyl (2E)-3-(2-aminophenyl)propenoate

(E)-Methyl 3-propenoate
133901-63-0

(E)-Methyl 3-propenoate

Conditions
ConditionsYield
With triethylamine In diethyl ether for 0.166667h; Ambient temperature;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(2-tert-Butyl-5-methylphenoxy)magnesium bromide
53863-60-8

(2-tert-Butyl-5-methylphenoxy)magnesium bromide

2-tert-Butyl-5-methylphenyl dichloroacetate
127354-47-6

2-tert-Butyl-5-methylphenyl dichloroacetate

Conditions
ConditionsYield
In toluene for 5h; Ambient temperature; also aluminium phenolate;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(-)-8-phenylmenthol
65253-04-5

(-)-8-phenylmenthol

(1R,2S,5R)-(+)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl dichloroacetate
152481-90-8

(1R,2S,5R)-(+)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl dichloroacetate

Conditions
ConditionsYield
at 100℃;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

9-hydroxyphenalenone sodium salt
129087-30-5

9-hydroxyphenalenone sodium salt

9-dichloroacetoxyphenalenone
129087-27-0

9-dichloroacetoxyphenalenone

Conditions
ConditionsYield
In tetrahydrofuran for 24h; Ambient temperature;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

trimethylsilyldicyclohexylphosphane
104202-80-4

trimethylsilyldicyclohexylphosphane

(dichloroacetyl)dicyclohexylphosphane

(dichloroacetyl)dicyclohexylphosphane

Conditions
ConditionsYield
In diethyl ether at -25℃;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

3-(2-Hydroxy-3-methoxy-phenyl)-cyclohex-2-enone

3-(2-Hydroxy-3-methoxy-phenyl)-cyclohex-2-enone

Dichloro-acetic acid 2-methoxy-6-(3-oxo-cyclohex-1-enyl)-phenyl ester

Dichloro-acetic acid 2-methoxy-6-(3-oxo-cyclohex-1-enyl)-phenyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

2-(3-indole)-ethanol
526-55-6

2-(3-indole)-ethanol

2-(Indol-3'-yl)ethyl Dichloroacetate
141972-14-7

2-(Indol-3'-yl)ethyl Dichloroacetate

Conditions
ConditionsYield
With pyridine In dichloromethane for 18h; kept in the dark;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(2,2-Bis-phenylsulfanyl-vinyl)-((S)-1-phenyl-ethyl)-amine
157734-48-0

(2,2-Bis-phenylsulfanyl-vinyl)-((S)-1-phenyl-ethyl)-amine

2,2-dichloro-N-<(S)-1-phenylethyl>-N-<2,2-bis(phenylthio)ethenyl>acetamide

2,2-dichloro-N-<(S)-1-phenylethyl>-N-<2,2-bis(phenylthio)ethenyl>acetamide

Conditions
ConditionsYield
With N,N-diethylaniline In benzene Heating;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

ethyl 3-(N,N-diethylamino)acrylate

ethyl 3-(N,N-diethylamino)acrylate

ethyl 2-dichloroacetyl-3-diethylaminoacrylate
1171114-12-7

ethyl 2-dichloroacetyl-3-diethylaminoacrylate

Conditions
ConditionsYield
With α-picoline In toluene at 0 - 20℃; for 1.5h;100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

1-[4-(4-amino-3-(pyrrolidin-1-yl)phenyl)piperazin-1-yl](1-methyl-1H-pyrrol-2-yl)methanone

1-[4-(4-amino-3-(pyrrolidin-1-yl)phenyl)piperazin-1-yl](1-methyl-1H-pyrrol-2-yl)methanone

1-[4-(4-N-dichloroacetyl-3-(pyrrolidin-1-yl)phenyl)piperazin-1-yl](1-methyl-1H-pyrrol-2-yl)methanone

1-[4-(4-N-dichloroacetyl-3-(pyrrolidin-1-yl)phenyl)piperazin-1-yl](1-methyl-1H-pyrrol-2-yl)methanone

Conditions
ConditionsYield
With triethylamine In dichloromethane100%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(E)-cyclooctene
931-89-5

(E)-cyclooctene

9,9-Dichloro-10-oxo-trans-bicyclo<6.2.0>decane
18332-33-7, 18332-34-8, 22374-13-6

9,9-Dichloro-10-oxo-trans-bicyclo<6.2.0>decane

Conditions
ConditionsYield
With triethylamine In hexane99%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

2-(trimethylsilyl)thiazole
79265-30-8

2-(trimethylsilyl)thiazole

2-(2,2-Dichloro-1-trimethylsilanyloxy-vinyl)-thiazole
79265-33-1

2-(2,2-Dichloro-1-trimethylsilanyloxy-vinyl)-thiazole

Conditions
ConditionsYield
With triethylamine In hexane Ambient temperature;99%
With triethylamine In hexane for 4h;80%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

4-[1-Diisopropylamino-meth-(E)-ylidene]-3,4-dihydro-2H-benzo[b]thiepin-5-one
106364-99-2

4-[1-Diisopropylamino-meth-(E)-ylidene]-3,4-dihydro-2H-benzo[b]thiepin-5-one

3,3-Dichloro-4-diisopropylamino-3,4,5,6-tetrahydro-1-oxa-7-thia-dibenzo[a,c]cyclohepten-2-one
106365-11-1

3,3-Dichloro-4-diisopropylamino-3,4,5,6-tetrahydro-1-oxa-7-thia-dibenzo[a,c]cyclohepten-2-one

Conditions
ConditionsYield
With triethylamine In toluene for 0.5h; Ambient temperature;99%
tert-butyl (S)-4-hydroxy-2-methylpent-2E-enoate
866572-55-6

tert-butyl (S)-4-hydroxy-2-methylpent-2E-enoate

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(E)-(S)-4-(2,2-Dichloro-acetoxy)-2-methyl-pent-2-enoic acid tert-butyl ester
866572-63-6

(E)-(S)-4-(2,2-Dichloro-acetoxy)-2-methyl-pent-2-enoic acid tert-butyl ester

Conditions
ConditionsYield
With pyridine; dmap In tetrahydrofuran for 2h;99%
With pyridine; dmap In tetrahydrofuran at 25℃; for 2h;99%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

2,2-difluoroacetyl fluoride
2925-22-6

2,2-difluoroacetyl fluoride

Conditions
ConditionsYield
With potassium fluoride; C30H22Cl4CrN4O2 at 80℃; for 2h; Reagent/catalyst;99%
With hydrogen fluoride; fluorinated chromium III oxide at 200 - 250℃; for 0.00555556h; Product distribution / selectivity; Gas phase;53%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

trans-2,5-diallylpyrrolidine

trans-2,5-diallylpyrrolidine

1-(2,5-diallyl-1-pyrrolidino)-2,2-dichloroethan-1-one

1-(2,5-diallyl-1-pyrrolidino)-2,2-dichloroethan-1-one

Conditions
ConditionsYield
With sodium hydroxide In dichloromethane; water at -15 - -10℃; Inert atmosphere;99%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

5-tert-butyl-3-methylbenzene-1,2-diol
2213-66-3

5-tert-butyl-3-methylbenzene-1,2-diol

5-(tert-butyl)-3-methyl-1,2-phenylene bis(2,2-dichloroacetate)

5-(tert-butyl)-3-methyl-1,2-phenylene bis(2,2-dichloroacetate)

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;99%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Estrone
53-16-7

Estrone

C20H22Cl2O3

C20H22Cl2O3

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃; for 24h;99%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate
212322-56-0

ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate

ethyl 3-{[(2-dichloromethyl-1-methyl-1H-benzimidazole-5-yl)carbonyl]-(2-pyridinyl)amino}propanoate

ethyl 3-{[(2-dichloromethyl-1-methyl-1H-benzimidazole-5-yl)carbonyl]-(2-pyridinyl)amino}propanoate

Conditions
ConditionsYield
In acetonitrile at -15 - 60℃;98.8%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

aniline
62-53-3

aniline

N-phenyl-2,2-dichloroacetamide
2563-99-7

N-phenyl-2,2-dichloroacetamide

Conditions
ConditionsYield
Stage #1: aniline With sodium hydrogencarbonate at 20℃; for 7h; Sonication;
Stage #2: dichloroacethyl chloride In tetrahydrofuran at 60℃; for 8h; Microwave irradiation;
98.6%
With triethylamine In dichloromethane Cooling;86.2%
With triethylamine In dichloromethane86%
2-aminopyridine
504-29-0

2-aminopyridine

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

2,2-dichloro-N-(pyridine-2-yl)acetamide
39089-41-3

2,2-dichloro-N-(pyridine-2-yl)acetamide

Conditions
ConditionsYield
for 1h;98%
With pyridine
With benzene
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

isopropylamine
75-31-0

isopropylamine

N-Isopropyl-2,2-dichloroacetamide
39063-24-6

N-Isopropyl-2,2-dichloroacetamide

Conditions
ConditionsYield
In dichloromethane98%
With 1,2-dichloro-ethane at -20 - -10℃;
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

phenol
108-95-2

phenol

phenyl dichloroacetate
10565-20-5

phenyl dichloroacetate

Conditions
ConditionsYield
With 1,1,1,3,3-pentafluoro-2,3-dichloropropane at 60 - 80℃; for 9h;98%
With triethylamine In dichloromethane Cooling;94.2%
for 3h; Reflux; Alkaline conditions;82%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

2-isopropenylaniline
52562-19-3

2-isopropenylaniline

2,2-Dichloro-N-acetamide
133901-65-2

2,2-Dichloro-N-acetamide

Conditions
ConditionsYield
With triethylamine In diethyl ether for 0.166667h; Ambient temperature;98%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

Aluminum; 2-tert-butyl-4-methyl-phenolate
127354-53-4

Aluminum; 2-tert-butyl-4-methyl-phenolate

A

ω,ω-Dichloro-2-hydroxy-3-tert-butyl-5-methylacetophenone
127354-45-4

ω,ω-Dichloro-2-hydroxy-3-tert-butyl-5-methylacetophenone

B

2-tert-Butyl-4-methylphenyl dichloroacetate
127354-46-5

2-tert-Butyl-4-methylphenyl dichloroacetate

Conditions
ConditionsYield
In toluene for 5h; Ambient temperature;A 98%
B 2%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

5-[1-Diphenylamino-meth-(E)-ylidene]-6,7-dihydro-5H-benzo[b]thiophen-4-one
84670-66-6

5-[1-Diphenylamino-meth-(E)-ylidene]-6,7-dihydro-5H-benzo[b]thiophen-4-one

3,3-Dichloro-4-diphenylamino-3,4,5,6-tetrahydro-thieno[2,3-h]chromen-2-one
90236-80-9

3,3-Dichloro-4-diphenylamino-3,4,5,6-tetrahydro-thieno[2,3-h]chromen-2-one

Conditions
ConditionsYield
With triethylamine98%

Dichloroacetyl chloride Chemical Properties

Molecular Structure of Dichloroacetyl chloride (CAS NO.79-36-7):

IUPAC Name: 2,2-Dichloroacetyl chloride
Canonical SMILES: C(C(=O)Cl)(Cl)Cl
InChI: InChI=1S/C2HCl3O/c3-1(4)2(5)6/h1H
InChIKey: FBCCMZVIWNDFMO-UHFFFAOYSA-N
Molecular Weight: 147.38774 [g/mol]
Molecular Formula: C2HCl3O
XLogP3-AA: 2.1
H-Bond Donor: 0
H-Bond Acceptor: 1
Appearance: colourless to light yellow fuming liquid
Melting Point: < 25 °C
EINECS: 201-199-9 
Index of Refraction: 1.466
Molar Refractivity: 25.85 cm3
Molar Volume: 93.1 cm3
Surface Tension: 36.7 dyne/cm
Density: 1.581 g/cm3
Flash Point: 31.8 °C
Enthalpy of Vaporization: 34.63 kJ/mol
Boiling Point: 107.5 °C at 760 mmHg
Vapour Pressure: 27 mmHg at 25 °C
Water Solubility: MAY DECOMPOSE
Sensitive: Moisture Sensitive
Stability: Stable. Combustible. Incompatible with water, alcohols and oxidizing agents. Fumes in air.
Product Categories: Pharmaceutical Intermediates; Organics; Acid Halides; Carbonyl Compounds; Organic Building Blocks
Classification Code: Mutation data; Skin / Eye Irritant; Tumor data 

Dichloroacetyl chloride Uses

 Dichloroacetyl chloride (CAS NO.79-36-7) is used as organic synthesis and pesticides, pharmaceutical intermediates, sheep felt fulling finishing, bleaching, bleaching, preservation, sterilization, disinfection and so on.

Dichloroacetyl chloride Toxicity Data With Reference

1.    

skn-rbt 2 mg/24H SEV

    85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,571.
2.    

eye-rbt 50 µg open SEV

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
3.    

orl-rat LD50:2460 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
4.    

ihl-rat LCLo:2000 ppm/4H

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
5.    

skn-rbt LD50:650 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.

Dichloroacetyl chloride Consensus Reports

Reported in EPA TSCA Inventory.

Dichloroacetyl chloride Safety Profile

Questionable carcinogen with experimental tumorigenic data. Moderately toxic by ingestion, inhalation, and skin contact. Corrosive to the skin, eyes, and mucous membranes. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl.
Safety Information of Dichloroacetyl chloride (CAS NO.79-36-7):
Hazard Codes: C,N
Risk Statements: 35-50
R35:Causes severe burns ;
R50:Very Toxic to aquatic organisms ;
Safety Statements: 9-26-45-61
S9:Keep container in a well-ventilated place ;
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice ;
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) ;
S61:Avoid release to the environment. Refer to special instructions safety data sheet ;
RIDADR: UN 1765 8/PG 2
WGK: Germany  2
RTECS: AO6650000
F: 19-21
Hazard Note: Corrosive/Moisture Sensitive
HazardClass: 8
PackingGroup: II

Dichloroacetyl chloride Standards and Recommendations

DOT Classification:  8; Label: Corrosive

Dichloroacetyl chloride Specification

 Dichloroacetyl chloride (CAS NO.79-36-7), its Synonyms are 2,2-Dichloroacetyl chloride ; alpha,alpha-Dichloroacetyl chloride ; Chlorid kyseliny dichloroctove ; Chlorure de dichloracetyle ; Acetyl chloride, 2,2-dichloro- .

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