Dicyclohexylamine supplier

Name
Dicyclohexylamine
EINECS 202-980-7
CAS No. 101-83-7
Article Data258
CAS DataBase
Density 0.912 g/cm³
Solubility 1 g/L (20 °C) in water
Melting Point -2 °C
Formula C₁₂H₂₃N
Boiling Point 256.1 °C at 760 mmHg
Molecular Weight 181.321
Flash Point 96.1 °C
Transport Information UN 2565 8/PG 3
Appearance Colorless liquid
Safety 26-36/37/39-45-60-61
Risk Codes 22-34-50/53
Molecular Structure
Hazard Symbols C,N
Synonyms Dodecahydrodiphenylamine;N,N-Dicyclohexylamine;N-Cyclohexylcyclohexanamine;NSC 3399;Dicyclohexylamine(8CI);Aminodicyclohexane;Bis(cyclohexyl)amine;D-CHA-T;
PSA 12.03000
LogP 3.63230

Synthetic route

: 62-53-3
aniline

A: 110-82-7
cyclohexane

B: 108-91-8
cyclohexylamine

C: 101-83-7
N-cyclohexyl-cyclohexanamine

D: 110-83-8
cyclohexene

Conditions

Conditions	Yield
With ammonia; hydrogen at 180 - 200℃;	A n/a B 98.4% C 0.08% D n/a
With hydrogen at 160 - 200℃; under 150015 Torr;	A n/a B 95.9% C 0.45% D n/a

...Expand

: 62-53-3
aniline

A: 108-91-8
cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With lithium hydroxide; hydrogen; 5% ruthenium/lithium aluminate In water at 150℃; under 44718.8 Torr; for 2.08333h; Product distribution / selectivity; Neat (no solvent);	A 97.1% B 1%
With lithium hydroxide; hydrogen; 5% activated charcoal-supported ruthenium catalyst In water at 150℃; under 44718.8 Torr; for 1.21667h; Product distribution / selectivity; Neat (no solvent);	A 91.8% B 5.73%
With hydrogen; 5% ruthenium/lithium aluminate at 150℃; under 44718.8 Torr; for 1.28333 - 3h; Product distribution / selectivity; Neat (no solvent);	A 89.2% B 0.08%

: dicyclohexyl-(3-methylbut-2-enyl)amine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
Stage #1: dicyclohexyl-(3-methylbut-2-enyl)amine With 2,2'-azobis(isobutyronitrile); para-thiocresol In benzene Heating; Stage #2: With hydrogenchloride	97%
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water at 20℃; for 4h; chemoselective reaction;	95%

: 39830-56-3
N,N-dicyclohexyl-p-toluenesulfonamide

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With pyrrolidine; samarium diiodide; water In tetrahydrofuran at 20℃; Inert atmosphere;	96%
With naphthalene; tetraethylammonium bromide In N,N-dimethyl-formamide at 0℃; Inert atmosphere; Electrolysis;	96%
Stage #1: N,N-dicyclohexyl-p-toluenesulfonamide With Na/K absorbed into silica gel In tetrahydrofuran at 20℃; Inert atmosphere; Stage #2: With water In tetrahydrofuran	83%
With diammonium hydrogenphosphate In tetrahydrofuran at 20℃; Product distribution / selectivity; Cooling with ice;	80%

: 108-91-8
cyclohexylamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With {[(PCy3)(CO)RuH]4(μ-O)(μ-OH)2}; 4-tert-Butylcatechol In chlorobenzene at 130℃; for 16h; Glovebox; Schlenk technique; Sealed tube; chemoselective reaction;	95%
With tris(triphenylphosphine)ruthenium(II) chloride In tetrahydrofuran at 185℃; for 5h;	92%
With NiCuFeO(x) In 5,5-dimethyl-1,3-cyclohexadiene for 24h; Inert atmosphere; Sealed tube; Reflux;	82%

: ((E)-But-2-enyl)-dicyclohexyl-amine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
Stage #1: ((E)-But-2-enyl)-dicyclohexyl-amine With 2,2'-azobis(isobutyronitrile); para-thiocresol In benzene Heating; Stage #2: With hydrogenchloride	95%

: N,N-dicyclohexylbenzylamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With formic acid; potassium hydroxide In ethanol at 70℃; for 1h;	93%
With Pd(OH)2/C In methanol for 8h; Reflux;	62%

: 108-91-8
cyclohexylamine

: 108-93-0
cyclohexanol

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With NiCuFeO(x) In 5,5-dimethyl-1,3-cyclohexadiene for 24h; Inert atmosphere; Sealed tube; Reflux;	92%
With lithium hydroxide In neat (no solvent) at 140℃; for 48h; Inert atmosphere;	74%
With nickel at 180 - 190℃; im Ruehrautoklaven;
With thorium dioxide at 290 - 320℃;

: 108-93-0
cyclohexanol

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With urea In 1,3,5-trimethyl-benzene at 141℃; under 760.051 Torr; for 16h; Inert atmosphere;	92%
With ammonium tetrafluroborate; sodium hydrogencarbonate; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] at 140℃; for 17h;	86%
With [Cp*Ir(NH3)3]I2; ammonia In water at 140℃; for 24h; Autoclave; Inert atmosphere;	85%

: N,N-dicyclohexyltrimethylmethanesulfonamide

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; methoxybenzene In dichloromethane at 0℃; desulfonation;	92%

: 10468-40-3
cyclohexanone N-cyclohexylimine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With ytterbium(III) triflate; bis(η5-cyclopentadinyl)dihydridomolybdenum In methanol at 50℃; for 24h;	90%
With ytterbium(III) triflate; bis(η5-cyclopentadinyl)dihydridomolybdenum In methanol at 50℃; for 24h; Product distribution; other reag.; other solvent; other temp.; other reaction time; varying amount of catalyst;	90%
With lithium; nickel dichloride In tetrahydrofuran for 6h; Ambient temperature;	78%

: 162466-77-5
N-allyl-N-cyclohexylcyclohexanamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water at 20℃; for 18h; chemoselective reaction;	90%
With Pd(OH)2/C In methanol for 1h; Reflux;	69%
Stage #1: N-allyl-N-cyclohexylcyclohexanamine With 2,2'-azobis(isobutyronitrile); para-thiocresol In benzene Heating; Stage #2: With hydrogenchloride	63%
With titanium(III) chloride; lithium In tetrahydrofuran for 20h; Heating;	47%
With water; [Ru(η3:η2:η3-dodeca-2,6,10-triene-1,12-diyl)Cl2] at 90℃; for 1.2h;	99 % Chromat.

: 108-94-1
cyclohexanone

: 108-91-8
cyclohexylamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With ammonium acetate In benzene for 1.5h; Leuckart type reaction; Reflux;	85%
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 80℃; under 6080 Torr; for 5h; Mechanism; analogous reaction of other ketones;	80%
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 80℃; under 6080 Torr; for 5h; Mechanism; analogous reaction with other ketones, analogous reaction of an other amine;	80%

: 122-39-4
diphenylamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With dichloro(μ-chloro)(μ-hydrido)bis(η-p-cymene)diruthenium(II); hydrogen In 1,4-dioxane at 90℃; under 37503.8 Torr; for 40h;	82%
With nickel at 150℃; under 91938.4 - 147102 Torr; Hydrogenation.ohne Loesungsmittel;
With nickel; methyl cyclohexane at 175℃; under 147102 - 161812 Torr; Hydrogenation;

: 108-91-8
cyclohexylamine

: 108-88-3
toluene

A: 1821-36-9
N-phenyl-2-cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With Co2Rh2/C at 180℃; under 760.051 Torr; for 18h; Temperature; Autoclave; Inert atmosphere;	A 12% B 82%

...Expand

: 62-53-3
aniline

A: 108-94-1
cyclohexanone

B: 108-91-8
cyclohexylamine

C: 101-83-7
N-cyclohexyl-cyclohexanamine

D: 108-93-0
cyclohexanol

Conditions

Conditions	Yield
With hydrogen; silica gel; rhodium In water at 49.9℃; under 15151.2 Torr; Product distribution; Other catalysts, other temperatures.;	A n/a B 81.5% C 2.8% D 15.7%
With hydrogen; 5 percent Rh/MgO; magnesium oxide In water at 49.9℃; under 15001.2 Torr; Product distribution; Hydrogenation in the presence of cyclohexylamine; cyclohexanone; cyclohexanol; dicyclohexylamine; ammonia and mixture of them.;	A 0.8% B 73.2% C 6.6% D 18.8%
With hydrogen; Ru(OH)Cl3 In water at 99.9℃; under 30002.4 Torr; Kinetics; Rate constant; Product distribution; energy data; variation of temperature, pressure; also in presence of oxides; activation energy;	A 1.5% B 64.7% C 1% D 32.5%

...Expand

: 62-53-3
aniline

A: 1821-36-9
N-phenyl-2-cyclohexylamine

B: 108-91-8
cyclohexylamine

C: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
aluminum oxide; ruthenium at 170℃; for 2.5h; Product distribution; Mechanism; investigation of the hydrogenation of aniline with various hydrogenation catalysts in the presence and abscence of the fused salts;	A 0.3% B 80.4% C 7%
With hydrogen; palladium/alumina at 240℃; for 2.5h; Product distribution; Mechanism; investigation of the hydrogenation of aniline with various hydrogenation catalysts in the presence and abscence of the fused salts;	A 1.1% B 20% C 51.9%
With formic acid; palladium on activated charcoal In methanol for 70h; Ambient temperature;	A 49 % Chromat. B 20 % Chromat. C 31 % Chromat.

...Expand

: 19520-87-7
2-Dicyclohexylamino-ethylacetat

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With bis(p-methoxyphenyl)methanone; water In acetonitrile for 3h; deprotection; Irradiation;	80%

: 108-94-1
cyclohexanone

: 62-53-3
aniline

A: 108-91-8
cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
Stage #1: cyclohexanone; aniline With hydrogen at 120℃; under 15001.5 Torr; Stage #2: at 180℃; Pressure; Temperature;	A 20.2% B 78.3%
Stage #1: cyclohexanone; aniline With ammonia; hydrogen at 150℃; under 37503.8 Torr; Stage #2: at 170℃; Reagent/catalyst; Temperature; Pressure;	A 65.3% B 32.8%

...Expand

: 82259-52-7
1,1-dicyclohexylhydrazine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With titanium(III) chloride; water In ethanol pH=7; Reflux; Alkaline aq. solution; Inert atmosphere;	76%
With titanium tetrachloride; magnesium In tetrahydrofuran at 20℃; Inert atmosphere;	70%

: 100504-97-0
N,N-dicyclohexylmethanesulfonamide

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
Stage #1: N,N-dicyclohexylmethanesulfonamide With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 0.25h; Inert atmosphere; Stage #2: With oxygen In tetrahydrofuran; hexane at 20℃; for 1h; Stage #3: With water In tetrahydrofuran; hexane	75%

: 108-91-8
cyclohexylamine

: 108-93-0
cyclohexanol

A: 10468-40-3
cyclohexanone N-cyclohexylimine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With Mg-Al hydrotalcite supported copper at 180℃; for 15h;	A 74% B 26%
With C27H19ClNO3PRu; potassium tert-butylate at 110 - 150℃; for 4h; Inert atmosphere;	A 38 %Spectr. B 9 %Spectr.

...Expand

: 1195-42-2
N-cyclohexylisopropylamine

A: 108-91-8
cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With dicarbonyl(chloro)(η5-pentaphenylcyclopentadienyl)ruthenium(II); ammonia In tert-Amyl alcohol at 170℃; for 23.5h; Inert atmosphere; Schlenk technique; Autoclave;	A 74% B 7.5%

: 98-95-3
nitrobenzene

A: 108-91-8
cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With Rh/Al2O3; hydrogen In tetrahydrofuran; water at 80℃; under 15001.5 Torr; for 24h;	A 73% B 27%
With 5 wt% ruthenium/carbon; hydrogen; sodium nitrite In tetrahydrofuran at 170℃; under 62256.2 Torr; for 4h; Solvent; Autoclave;
With dodecane; 5 wt% ruthenium/carbon; hydrogen In tetrahydrofuran at 140℃; under 75007.5 Torr; for 3h; Reagent/catalyst; Autoclave;
With hydrogen; sodium chloride In isopropyl alcohol at 90℃; under 45004.5 Torr; for 0.833333h; Catalytic behavior; Reagent/catalyst;

: (E)-N,N-dicyclohexyl-3-phenyl-2-propenylamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
Stage #1: (E)-N,N-dicyclohexyl-3-phenyl-2-propenylamine With 2,2'-azobis(isobutyronitrile); para-thiocresol In benzene Heating; Stage #2: With hydrogenchloride	70%

: 98-95-3
nitrobenzene

A: 108-91-8
cyclohexylamine

B: 62-53-3
aniline

C: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With octylated silica; hydrogen; sodium 4-dodecylbenzenesulfonate; {[(CH3)(C8H17)3N](+)[RhCl4](-)} at 80℃; under 10343 Torr; for 24h;	A 25% B 6% C 69%
With propane; hydrogen at 200 - 250℃; under 60006 Torr; Supercritical conditions; Flow reactor;	A 29 %Chromat. B 9 %Chromat. C 58 %Chromat.
With dodecane; 5 % platinum on carbon; hydrogen In tetrahydrofuran at 140℃; under 75007.5 Torr; for 3h; Reagent/catalyst; Autoclave;

...Expand

: 626-62-0
1-iodocyclohexane

: 108-91-8
cyclohexylamine

: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With copper(l) iodide; tert-butylimino-tri(pyrrolidino)phosphorane; 1,1'-bi-2-naphthol In N,N-dimethyl-formamide; acetonitrile at -10℃; for 24h; Irradiation;	69%

: 10468-40-3
cyclohexanone N-cyclohexylimine

A: 108-91-8
cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With sodium tetrahydroborate; nickel boride In methanol Yield given;	A 68% B n/a

: 1122-60-7
1-nitrocyclohexane

A: 108-91-8
cyclohexylamine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With sodium tetrahydroborate; nickel boride In methanol Yields of byproduct given;	A 68% B n/a
With Pt/Al2O3; hydrogen In ethanol at 100℃; under 4500.45 Torr; for 3h; Autoclave; chemoselective reaction;

: 110-89-4
piperidine

: 108-91-8
cyclohexylamine

A: 3319-01-5
1-cyclohexylpiperidine

B: 101-83-7
N-cyclohexyl-cyclohexanamine

Conditions

Conditions	Yield
With platinum-nickel nanoclusters on activated carbon; hydrogen at 160℃; under 760.051 Torr; Flow reactor; chemoselective reaction;	A 62% B 26.3%

...Expand

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 947-92-2
N-nitrosodicyclohexylamine

Conditions

Conditions	Yield
Stage #1: N-cyclohexyl-cyclohexanamine With n-butyllithium In tetrahydrofuran Metallation; Stage #2: With nitrogen(II) oxide In tetrahydrofuran at -78℃; for 3h; Nitrosation;	100%
Stage #1: N-cyclohexyl-cyclohexanamine With n-butyllithium In hexane Stage #2: With nitric oxide In tetrahydrofuran under 759811 Torr; for 3h; cooling;	100%
With [NO(1+)18-crown-6H(NO3)2(1-)] In dichloromethane at 20℃; for 0.0833333h;	100%

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 106-89-8
epichlorohydrin

: 150389-77-8
1-Chloro-3-dicyclohexylamino-propan-2-ol

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%

: 31562-43-3
tert-butylsulfinyl chloride

: 101-83-7
N-cyclohexyl-cyclohexanamine

: N,N-dicyclohexyltrimethylmethanesulfinamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0℃; sulfinylation;	100%

: 67-56-1
methanol

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 7560-83-0
N-Methyldicyclohexylamine

Conditions

Conditions	Yield
chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium (II) at 100℃;	100%
With TiO2 supported nano-Pd(0.8) catalyst In water at 20℃; for 15h; Inert atmosphere; Irradiation; Green chemistry;	93%
With [Cp*Ir(2-(1H-benzo[d]imidazol-2-yl)-1H-benzo[d]imidazole)Cl][Cl]; caesium carbonate at 120℃; for 12h; Schlenk technique;	82%

: 50-00-0
formaldehyd

: 536-74-3
phenylacetylene

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 801304-96-1
N-cyclohexyl-N-(3-phenylprop-2-yn-1-yl)cyclohexanamine

Conditions

Conditions	Yield
With copper(l) iodide In water at 25℃; for 1.5h; Mannich reaction;	100%
With polystyrene-supported 1-benzyl-1H-imidazole-Ag(I) catalyst at 20℃; for 24h; Inert atmosphere;	97%
copper(l) iodide In water; dimethyl sulfoxide at 30℃; for 20h;	96%

...Expand

: 24424-99-5
di-tert-butyl dicarbonate

: 101-83-7
N-cyclohexyl-cyclohexanamine

: dicyclohexylcarbamic acid tert-butyl ester

Conditions

Conditions	Yield
With perchloric acid at 30 - 35℃; for 0.75h;	100%
at 20℃; for 0.166667h; Ionic liquid;	100%
With 1,4-disulfopiperazine-1,4-diium chloride In neat (no solvent) at 20℃; for 1h; Green chemistry; chemoselective reaction;	96%

: 109-72-8, 29786-93-4
n-butyllithium

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 935753-45-0
2,2-dicyclohexyl-1-butylidenehydrazine

Conditions

Conditions	Yield
Stage #1: N-cyclohexyl-cyclohexanamine With n-butyllithium In hexane Stage #2: With nitric oxide In tetrahydrofuran under 759811 Torr; for 3h; cooling; Stage #3: n-butyllithium In tetrahydrofuran; hexane	100%

: 135077-83-7
3-(1-adamantyl)-4-vinylbenzoic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 135077-84-8
3-(1-adamantyl)-4-vinylbenzoyl chloride

Conditions

Conditions	Yield
With thionyl chloride In diethyl ether; dichloromethane	100%

: 120-80-9
benzene-1,2-diol

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 76128-65-9
N-(trimethoxysilylmethyl)hexahydroazepin-2-one

: dicyclohexylammonium bis(1,2-catecholato-O,O')-[(2-oxohexahydroazepin-1-yl)methyl-C,O]silicate

Conditions

Conditions	Yield
In o-xylene at 130 - 140℃;	100%

...Expand

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 4693-92-9
dicyclohexylamine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether; water at 20℃; for 0.5h;	100%
With hydrogenchloride In 1,4-dioxane; water at 20℃; for 12h;	98%
With hydrogenchloride In diethyl ether; hexane Inert atmosphere;

: 18934-81-1
N-(tert-butyloxycarbonyl)-12-aminododecanoic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 943923-29-3
dicyclohexylammonium 12-((tert-butoxycarbonyl)amino)dodecanoate

Conditions

Conditions	Yield
In methanol at 20℃; for 0.166667h;	100%
In methanol at 20℃; for 0.166667h;

: 101-83-7
N-cyclohexyl-cyclohexanamine

: dicyclohexylamine hydroiodide

Conditions

Conditions	Yield
With hydrogen iodide In 1,4-dioxane; water at 20℃; for 12h;	100%
With hydrogen iodide In diethyl ether; water at 20℃; for 0.5h;	79%

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 73254-21-4
dicyclohexylamine hydrobromide

Conditions

Conditions	Yield
With hydrogen bromide In 1,4-dioxane; water at 20℃; for 12h;	100%
With hydrogen bromide In diethyl ether; water at 20℃; for 0.5h;	74%

: 123-38-6
propionaldehyde

: 101-83-7
N-cyclohexyl-cyclohexanamine

: N-cyclohexyl-N-propylcyclohexanamine

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; Inert atmosphere;	100%
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 24h; Inert atmosphere;

: 683-85-2
N,N-dimethylaminodichlorophosphane

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C14H28ClN2P

Conditions

Conditions	Yield
Stage #1: N-cyclohexyl-cyclohexanamine With n-butyllithium In diethyl ether; hexane at -78 - 0℃; for 0.5h; Inert atmosphere; Stage #2: N,N-dimethylaminodichlorophosphane In diethyl ether; cyclohexane at 20℃; for 0.75h; Inert atmosphere;	100%

: O-[1-(propofol-O-yl)]cyclohex-1-yl-monoester phosphoric acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: O-[1-(propofol-O-yl)]cyclohexan-1-yl-monoester phosphate bis-dicyclohexylamine salt

Conditions

Conditions	Yield
In water at 20℃; for 1h;	100%

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 331-25-9
(3-fluorophenyl)acetic acid

: C8H7FO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 405-50-5
p-Fluorophenylacetic acid

: C8H7FO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 644-36-0
o-methylphenylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C9H10O2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 621-36-3
m-methylphenylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C9H10O2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 622-47-9
4-tolylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C9H10O2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7NO4*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 1877-73-2
3-nitro-benzeneacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7NO4*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 104-03-0
4-nitrobenzeneacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7NO4*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 103-82-2
phenylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: dicyclohexylammonium phenylacetate

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 18698-97-0
ortho-bromophenylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7BrO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 1878-67-7
3-Bromophenylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7BrO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 1878-68-8
2-(4-bromophenyl)-acetic acid

: C8H7BrO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 2444-36-2
2'-chloro-benzeneacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7ClO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

: 1878-65-5
3-chlorophenylacetic acid

: 101-83-7
N-cyclohexyl-cyclohexanamine

: C8H7ClO2*C12H23N

Conditions

Conditions	Yield
In methanol at 20℃;	100%

Dicyclohexylamine Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 178.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 22 (1980),p. 55.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Dicyclohexylamine Standards and Recommendations

DOT Classification: 8; Label: Corrosive

Dicyclohexylamine Specification

The N,N-Dicyclohexylamine, with the CAS registry number 101-83-7, is also known as Dodecahydrodiphenylamine. It belongs to the product categories of Pharmaceutical Intermediates; Amines; C11 to C38; Nitrogen Compounds; Aliphatics Volatiles/ Semivolatiles; Alpha Sort; Chemical Class; D; DAlphabetic; DIA - DIC; Analytical Reagents for General Use; C-D, Puriss p.a.; Puriss p.a.. Its EINECS registry number is 202-980-7. This chemical's molecular formula is C₁₂H₂₃N and molecular weight is 181.31772. Its IUPAC name is called N-cyclohexylcyclohexanamine. This chemical's classification codes are Enzyme inhibitors; Mutation Data; Skin / Eye Irritant; Tumor Data.

Physical properties of N,N-Dicyclohexylamine: (1)ACD/LogP: 3.69; (2)ACD/LogD (pH 5.5): 0.59; (3)ACD/LogD (pH 7.4): 0.64; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1.92; (7)ACD/KOC (pH 7.4): 2.15; (8)#H bond acceptors: 1; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.487; (12)Molar Refractivity: 57.12 cm³; (13)Molar Volume: 198.2 cm³; (14)Surface Tension: 33.1 dyne/cm; (15)Density: 0.91 g/cm³; (16)Flash Point: 96.1 °C; (17)Enthalpy of Vaporization: 49.36 kJ/mol; (18)Boiling Point: 256.1 °C at 760 mmHg; (19)Vapour Pressure: 0.0157 mmHg at 25°C.

Preparation of N,N-Dicyclohexylamine: this chemical can be prepared by aniline. This reaction will need reagent nickel catalyst.

N,N-Dicyclohexylamine can be prepared by aniline

Uses of N,N-Dicyclohexylamine: it can be used to produce chloro-acetic acid dicyclohexylamide at temperature of 25 °C. This reaction will need reagent CH₂Cl₂ with reaction time of 12 hours. The yield is about 61%.

N,N-Dicyclohexylamine can be used to produce chloro-acetic acid dicyclohexylamide

When you are using this chemical, please be cautious about it as the following:
This chemical may destroy living tissue on contact and may cause burns. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1CCC(CC1)NC2CCCCC2
(2)InChI: InChI=1S/C12H23N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h11-13H,1-10H2
(3)InChIKey: XBPCUCUWBYBCDP-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	500mg/kg (500mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 468, 1986.
mouse	LD50	subcutaneous	135mg/kg (135mg/kg)		Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. Vol. 4, Pg. 659, 1958.
rabbit	LDLo	subcutaneous	500mg/kg (500mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Industrial and Engineering Chemistry. Vol. 29, Pg. 1247, 1937.
rat	LD50	oral	373mg/kg (373mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 468, 1986.

Product Name

Dicyclohexylamine

Synthetic route

Dicyclohexylamine Consensus Reports

Dicyclohexylamine Standards and Recommendations

Dicyclohexylamine Specification

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