Dimethylglyoxime supplier

Name
Dimethylglyoxime
EINECS 202-420-1
CAS No. 95-45-4
Article Data52
CAS DataBase
Density 1.17 g/cm³
Solubility insoluble in water
Melting Point 240-241 °C(lit.)
Formula C₄H₈N₂O₂
Boiling Point 271.529 °C at 760 mmHg
Molecular Weight 116.12
Flash Point 158.376 °C
Transport Information
Appearance white crystalline powder
Safety 22-24/25-36
Risk Codes 22-20/21/22
Molecular Structure
Hazard Symbols Xn
Synonyms 2,3-Butanedione,dioxime (8CI,9CI);2,3-Diisonitrosobutane;Biacetyl dioxime;Chugaev's reagent;2,3-Butanedione,2,3-dioxime;NSC 9;Reagents, Chugaev's;Diacetyl dioxime;
PSA 65.18000
LogP 0.68660

Synthetic route

: 7647-01-0
hydrogenchloride

: triphenylantimony dimethylglyoximate

A: 594-31-0, 34716-91-1, 20265-29-6
triphenylantimony dichloride

B: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
In hydrogenchloride react. antimony compd. with concd. HCl;	A 99% B n/a

...Expand

: 431-03-8
dimethylglyoxal

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With pyridine; hydroxylamine hydrochloride In methanol for 1h; Reflux;	95%
With pyridine; hydroxylamine hydrochloride In methanol for 1h; Inert atmosphere; Reflux;	92%

: 135636-66-7
butane-2,3-dione mono-oxime

A: 89356-40-1
2-(1-hydroxyiminoethyl)-2,4,5-trimethyl-2H-imidazole 1-oxide

B: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With ammonium carbonate In ethanol; water for 72h; Heating;	A 35% B 9.0 g

: nickel(II) bis(dimethylglyoximate)

A: 95-45-4
butane-2,3-dione dioxime

B: nickel(II) nitrate

Conditions

Conditions	Yield
With nitric acid In not given	A 32% B n/a
With HNO3 In not given	A 32% B n/a

: 151-50-8
potassium cyanide

: 135636-66-7
butane-2,3-dione mono-oxime

A: 89356-40-1
2-(1-hydroxyiminoethyl)-2,4,5-trimethyl-2H-imidazole 1-oxide

B: 95-45-4
butane-2,3-dione dioxime

: 89356-41-2
1-hydroxytetrahydro-4,5-dimethyl-2-oxoimidazole-4,5-dicarboxylic acid

: 89356-38-7
(3aRS,6aSR)-6-amino-1,3,3a,6a-tetrahydro-1-hydroxy-3a,6a-dimethylpyrrolo<3,4-d>imidazole-2,4-dione

Conditions

Conditions	Yield
With ammonium carbonate; water In ethanol at 70℃; for 4h; Product distribution; Mechanism;	A 0.5 g B 0.07 g C 3% D 26.5%
With ammonium carbonate; water In ethanol at 70℃; for 4h;	A 0.5 g B 0.07 g C 3% D 26.5%

...Expand

: 151-50-8
potassium cyanide

: 135636-66-7
butane-2,3-dione mono-oxime

: 89356-43-4
(3aRS,6aSR)-1,3,3a,6a-tetrahydro-1-hydroxy-3a,6a-dimethyl-5H-pyrrolo<3,4-d>imidazole-2,4,6-trione

B: 95-45-4
butane-2,3-dione dioxime

: 89356-41-2
1-hydroxytetrahydro-4,5-dimethyl-2-oxoimidazole-4,5-dicarboxylic acid

: 89356-38-7
(3aRS,6aSR)-6-amino-1,3,3a,6a-tetrahydro-1-hydroxy-3a,6a-dimethylpyrrolo<3,4-d>imidazole-2,4-dione

Conditions

Conditions	Yield
With ammonium carbonate; water In ethanol at 70℃; for 4h;	A 0.4 g B 0.07 g C 3% D 26.5%

...Expand

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With sodium hydroxide; water; sodium nitrite ueber mehrere Stufen;
With sodium hydroxide dann versetzt mit Natriumnitrit und leitet Schwefeldioxyd ein;

: 29027-51-8
diacetyldioxime monomethylether

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With hydrogenchloride

: 29027-51-8
diacetyldioxime monomethylether

A: 617-32-3
butane-2,3-dione-2-methoxime

B: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With hydrogenchloride at 60℃;

: 17235-39-1
2,3-dinitro-butane

: 95-45-4
butane-2,3-dione dioxime

: 96-29-7
ethyl methyl ketone oxime

: 135636-66-7
butane-2,3-dione mono-oxime

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With sulfuric acid at 40℃;

: 135636-66-7
butane-2,3-dione mono-oxime

: 57-13-6
urea

A: 28115-25-5
tetrahydro-3a,6a-dimethylimidazo<4,5-d>imidazole-2,5-(1H,3H)-dione

B: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With ethanol; sulfuric acid

...Expand

: 135636-66-7
butane-2,3-dione mono-oxime

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With hydroxylamine
With acid solution; sodium hydroxylamine-O-sulfonate at 70℃;

: 78-93-3
butanone

: 110-46-3
isopentyl nitrite

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With hydrogenchloride at 40 - 50℃; ueber mehrere Stufen;

: 78-93-3
butanone

: 110-46-3
isopentyl nitrite

A: 95-45-4
butane-2,3-dione dioxime

B: 431-03-8
dimethylglyoxal

Conditions

Conditions	Yield
With hydrogenchloride

...Expand

: 78-93-3
butanone

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
Darstellung;

: 563-86-0
2,3-butane diamine

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With titanium(IV) sulfate; titanium(III) sulphate; sulfuric acid at 32.85℃; Equilibrium constant; Reduction;

: 20668-33-1
6,7-dimethylquinoline

: 67-66-3
chloroform

: 10028-15-6
ozone

A: 860716-16-1
pyrrolo[3,4-b]pyridine-5,7-dione dioxime

B: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
at -30℃; Beh. des Rktgem. mit Hydroxylamin-hydrochlorid und wss. Natriumcarbonat;

...Expand

: 1721-89-7
2,3-dimethylquinoline

: 67-66-3
chloroform

: 10028-15-6
ozone

A: 557-30-2
glyoxime

B: 95-45-4
butane-2,3-dione dioxime

C 5,6-dimethyl-pyrrolo<3,4-b>pyridine-1,3-dione dioxime: 5,6-dimethyl-pyrrolo<3,4-b>pyridine-1,3-dione dioxime

Conditions

Conditions	Yield
at -40℃; anschl. mit Hydroxylamin-hydrochlorid und wss. Natriumcarbonat;

...Expand

3.3-dichlorobutanone: 3.3-dichlorobutanone

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With hydroxylamine

dimethylfuroxane: dimethylfuroxane

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With acetic acid; zinc

: 431-03-8
dimethylglyoxal

hydroxylamine hydrochloride: hydroxylamine hydrochloride

: 95-45-4
butane-2,3-dione dioxime

Conditions

Conditions	Yield
With sodium carbonate

: 135636-66-7
butane-2,3-dione mono-oxime

hydroxylamine hydrochloride: hydroxylamine hydrochloride

: 95-45-4
butane-2,3-dione dioxime

: 7647-01-0
hydrogenchloride

: 135636-66-7
butane-2,3-dione mono-oxime

: 57-13-6
urea

concentrated alcohol: concentrated alcohol

A: 95-45-4
butane-2,3-dione dioxime

B dimethylacetylene-diurein: dimethylacetylene-diurein

...Expand

: 7664-93-9
sulfuric acid

: 135636-66-7
butane-2,3-dione mono-oxime

: 57-13-6
urea

concentrated alcohol: concentrated alcohol

A: 95-45-4
butane-2,3-dione dioxime

B dimethylacetylene-diurein: dimethylacetylene-diurein

...Expand

: 7647-01-0
hydrogenchloride

: 64-17-5
ethanol

: 135636-66-7
butane-2,3-dione mono-oxime

: 57-13-6
urea

A: 95-45-4
butane-2,3-dione dioxime

B dimethylacetylenediurein: dimethylacetylenediurein

...Expand

: 64-17-5
ethanol

: 7664-93-9
sulfuric acid

: 135636-66-7
butane-2,3-dione mono-oxime

: 57-13-6
urea

A: 95-45-4
butane-2,3-dione dioxime

B dimethylacetylenediurein: dimethylacetylenediurein

...Expand

: 107-29-9
Acetaldehyde oxime

: 135636-66-7
butane-2,3-dione mono-oxime

A: 95-45-4
butane-2,3-dione dioxime

B oxy-trimethyloxadiazin;acetaldehyde: oxy-trimethyloxadiazin;acetaldehyde

...Expand

: 2648-57-9
3,3-Dichloro-2-butanone

NH3O: NH3O

: 95-45-4
butane-2,3-dione dioxime

: 41476-75-9
bis(dipiperidinyldithiocarbamato)nickel(II)

: 95-45-4
butane-2,3-dione dioxime

: nickel (dimethylglyoximate)(piperidine dithiocarbamate)

Conditions

Conditions	Yield
With ammonia In ethanol byproducts: C5H10NCS2NH4; addn. of aq. NH3 to a mixt. of nickel complex and ligand in EtOH, refluxing for 30 min; filtration, washing with ethanol, ether, drying in vac.; elem. anal.;	100%

: 75895-97-5
(phthaloyl)bis(triphenylphosphino)(chloro)cobalt

: 95-45-4
butane-2,3-dione dioxime

: 101565-42-8
(phthaloyl)(dimethylglyoxime)(triphenylphosphine)chloro-cobalt

Conditions

Conditions	Yield
In acetonitrile Co-complex, dimethylglyoxime, and MeCN were refluxed with stirring under an N2 atmosphere until all of the starting material had solubilized; soln. was cooled, MeCN removed, residue was triturated with Et2O; elem. anal.;	100%

: 1079097-20-3, 14267-17-5, 52610-81-8
bis(N,N-diethyldithiocarbamato)nickel(II)

: 95-45-4
butane-2,3-dione dioxime

: 110975-93-4
Ni((CH3CH2)2NCS2)(CH3CNOCNOHCH3)

Conditions

Conditions	Yield
With ammonia In ethanol byproducts: (CH3CH2)2NCS2NH4; addn. of aq. NH3 to a mixt. of nickel complex and ligand in EtOH, refluxing for 30 min; filtration, washing with ethanol, ether, drying in vac.; elem. anal.;	100%

: cobalt(II) chloride hexahydrate

: 95-45-4
butane-2,3-dione dioxime

: dichloro(dimethylglyoxime)(dimethylglyoximato)cobalt(III)

Conditions

Conditions	Yield
With oxygen In acetone at 20℃; for 1h; Schlenk technique; Inert atmosphere;	100%
With air In acetone for 0.333333h; Sealed tube;	99%
In acetone for 0.166667h;	79%

: cobalt(II) bromide hydrate

: 95-45-4
butane-2,3-dione dioxime

: dibromo(dimethylglyoxime)(dimethylglyoximato)cobalt(III)

Conditions

Conditions	Yield
With oxygen In acetone at 20℃; for 1h; Schlenk technique; Inert atmosphere;	100%

: 14099-01-5
rhenium(I) pentacarbonyl chloride

: 95-45-4
butane-2,3-dione dioxime

: 1173885-94-3
[ReCl(CO)3(dimethylglyoxime)]

Conditions

Conditions	Yield
In methanol Re complex was mixed with ligand (1 equiv.); MeOH was added; refluxed for 4 h; evapd.; elem. anal.;	98%

: 75992-73-3, 25794-47-2, 30729-25-0, 15274-33-6, 22840-91-1, 14568-13-9
cis-dichlorobis(dimethylsulfoxide)platinum(II)

: 95-45-4
butane-2,3-dione dioxime

: cis-bis(α-glyoximate)platinum(II)

Conditions

Conditions	Yield
With triethylamine In methanol for 2h; Reflux;	97%

: rhodium(III) chloride trihydrate

: 95-45-4
butane-2,3-dione dioxime

: trans-dichloro(dimethylglyoximato)(dimethylglyoxime)rhodium(III)

Conditions

Conditions	Yield
In ethanol; water addn. of hot soln. of glyoxime in 95% aq. ethanol to boiling purple suspension of RhCl3; immediately discoloration of mixture to yellow; heating at reflux for 1 h; cooling to 0°C;; pptn.; drying;;	96%

: 1692-25-7
3-pyridylboronic acid

: 95-45-4
butane-2,3-dione dioxime

: iron(II) chloride

: C22H26B2FeN8O6

Conditions

Conditions	Yield
In methanol Reflux;	96%

...Expand

: 95-45-4
butane-2,3-dione dioxime

: 4975-21-7
3,4-dimethylfurazan

Conditions

Conditions	Yield
With potassium hydroxide; caesium carbonate In ethylene glycol at 110 - 160℃;	95%
With succinic acid anhydride at 160℃; Neat (no solvent);	30%
With potassium hydroxide In ethylene glycol at 160 - 190℃;

: 95-45-4
butane-2,3-dione dioxime

: nickel(II) hydroxide

: nickel(II) bis(dimethylglyoximate)

Conditions

Conditions	Yield
In solid metal to ligand ratio 1:2, static load (10 MPa, shear angle 45-90°), contact time no more than 15 min;	95%

: 373-02-4, 14998-37-9, 33025-09-1, 94044-50-5, 98268-31-6
nickel diacetate

: 95-45-4
butane-2,3-dione dioxime

: nickel(II) bis(dimethylglyoximate)

Conditions

Conditions	Yield
In solid metal to ligand ratio 1:2, static load (10 MPa, shear angle 45-90°), contact time no more than 15 min;	95%
In ethanol in concd. soln.; short heating on water bath; filtration, multiple washing with alcohol;
In ethanol in concd. soln.; short heating on water bath; filtration, multiple washing with alcohol;

: nickel hydroxocarbonate

: 95-45-4
butane-2,3-dione dioxime

: nickel(II) bis(dimethylglyoximate)

Conditions

Conditions	Yield
In solid metal to ligand ratio 1:2, static load (10 MPa, shear angle 45-90°), contact time no more than 15 min;	95%

: sodium metavanadate * water

: 95-45-4
butane-2,3-dione dioxime

: 6Na(1+)*5V(5+)*5V(4+)*23O(2-)*C4H6N2O2*5OH(1-)*11H2O=Na6V10O23(C4H6N2O2)(OH)5*11H2O

Conditions

Conditions	Yield
With H2SO4 In ethanol; water byproducts: H(1+); room temp.; addn. of aq. soln. of metal compd. (pH = 2.5, H2SO4) to soln. of ligand (in EtOH), stirring (pptn.); filtration, washing (H2O/EtOH = 1/1), drying (50°C); elem. anal.;	95%

: 108-89-4
picoline

: indium trichloride trihydrate

: cobalt(II) chloride hexahydrate

: 95-45-4
butane-2,3-dione dioxime

: {Co(4-picoline)2(MeC(NOH)C(NO)Me)2}{InCl4(4-picoline)2}

Conditions

Conditions	Yield
In methanol addn. of CoCl26H2O in MeOH to dimethylglyoxime, heating (water bath), addn. of pyridine and MeOH soln. of InCl33H2O (ratio of Co/dioxime/In/amine 1:2:1:5, stirring), heating (stirring until substances dissolved); crystn. on cooling, filtration off, washing (MeOH, ether), drying (air); elem. anal.;	94%

...Expand

: 110-86-1
pyridine

: 6147-53-1
cobalt(II) diacetate tetrahydrate

: 64-19-7
acetic acid

: 95-45-4
butane-2,3-dione dioxime

: 3623-15-2
phenyl propargyl ketone

: 25153-21-3, 287200-31-1
(3-phenyl-1-propen-3-one-1-yl)(pyridine)bis(dimethylglyoximato)cobalt(III)

Conditions

Conditions	Yield
With Zn In tetrahydrofuran under N2, Co(CH3COO)2*4H2O, dimethylglyoxime, pyridine and zinc dust were all combined in THF and refluxed 15 min, cooled to 25°C, C6H5COCCH was added, the mixt. was refluxed for 1 h, the mixt. was cooled to 25°C, CH3COOH was added; the soln. was poured into ice water containing pyridine, the product was extd. with CH3CH2OCOCH3, dried (MgSO4), concd. (vac.), the solid was triturated with pentane/(CH3CH2)2O; elem. anal.;	94%

Yield

With Zn In tetrahydrofuran under N2, Co(CH3COO)2*4H2O, dimethylglyoxime, pyridine and zinc dust were all combined in THF and refluxed 15 min, cooled to 25°C, C6H5COCCH was added, the mixt. was refluxed for 1 h, the mixt. was cooled to 25°C, CH3COOH was added; the soln. was poured into ice water containing pyridine, the product was extd. with CH3CH2OCOCH3, dried (MgSO4), concd. (vac.), the solid was triturated with pentane/(CH3CH2)2O; elem. anal.;

94%

...Expand

: sodium metavanadate * water

: 95-45-4
butane-2,3-dione dioxime

: 6Na(1+)*8V(5+)*2V(4+)*26O(2-)*2C4H6N2O2*2OH(1-)*16H2O=Na6V10O26(C4H6N2O2)2(OH)2*16H2O

Conditions

Conditions	Yield
With H2SO4 In ethanol; water byproducts: H(1+); room temp.; addn. of aq. soln. of metal compd. (pH = 4.0, H2SO4) to soln. of ligand (in EtOH), stirring (pptn.); filtration, washing (H2O/EtOH = 1/1), drying (50°C); elem. anal.;	92%

: (OCH3)((CH3)2CH)C4O2Co(P(C6H5)3)2Cl

: 95-45-4
butane-2,3-dione dioxime

: (OCH3)((CH3)2CH)C4(O)2 cobalt(triphenylphosphine)(dimethylglyoxime)

Conditions

Conditions	Yield
In acetonitrile 24 h/room temp.;;	91%
In acetonitrile	91%

: cobalt(II) chloride hexahydrate

: 95-45-4
butane-2,3-dione dioxime

: 126-98-7
methacrylonitrile

: β-cyanopropylpyridinatocobaloxime

Conditions

Conditions	Yield
With pyridine; sodium hydroxide; hydrogen In methanol; water addn. of alkene to soln. of CoCl2*6H2O, dimethylglyoxime and pyridine in MeOH (room temp.), degassing (N2, 20 min), addn. of aq. NaOH, degassing (15 min), exchange of N2 for H2 (<1 h); addn. of H2O, extn. (CH2Cl2), drying (MgSO4), evapn., chromy (silica gel) and/or recrystn (CH2Cl2-petroleum ether);	91%

...Expand

: cobalt(II) chloride hexahydrate

: 2695-47-8
6-Bromo-1-hexene

: 95-45-4
butane-2,3-dione dioxime

: 3430-22-6
3-Bromo-4-methylpyridin

: (3-bromo-4-methylpyridine)bis(dimethylglyoximato)-5-hexenylcobalt(III)

Conditions

Conditions	Yield
With sodium hydroxide; sodium tetrahydroborate In methanol stirring CoCl2, glyoxime in CH3OH at -20°C under N2; addn. of 50% aq. NaOH soln., 3-bromo-4-methylpyridine, NaBH4 in CH3OH; stirring at 20°C for 1 h; addn. of bromide at -20, stirring at 20°C in dark for 14 h;; addn. of water containing 1 drop 3-bromo-4-methylpyridine to oily residue; pptn.; drying; elem. anal.;	91%

...Expand

: 95-45-4
butane-2,3-dione dioxime

: 3,5-dibromophenylboronic acid

: iron(II) chloride

: C24H24B2Br4FeN6O6

Conditions

Conditions	Yield
In methanol at 70℃; for 4h; Inert atmosphere; Schlenk technique;	91%

...Expand

: 111-34-2
-butyl vinyl ether

: 95-45-4
butane-2,3-dione dioxime

: 128224-27-1
dimethylglyoxal O,O'-di(1-butoxyethyl)dioxime

Conditions

Conditions	Yield
With hydrogen bromide In diethyl ether at 25℃; for 48h;	90%

: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer

: 95-45-4
butane-2,3-dione dioxime

: {(pentamethylcyclopentadienyl)(dmg)rhodium(III)(Cl)}Cl

Conditions

Conditions	Yield
In methanol stirring for 5 min; concn. and layering with ether; elem. anal.;	90%

: uranium(VI) trioxide

: 95-45-4
butane-2,3-dione dioxime

: uranyl diaquadimethylglyoximate trihydrate

Conditions

Conditions	Yield
In water dimetylglyoxime added to suspn. of UO3 in H2O; mixt. stirred under heating for 6 h (molar ratio U:C4H8N2O2 = 1:1.23); ppt. filtered off; washed (H2O, EtOH, ether); dried on filter in air flow; elem. anal.;	90%

: (CH3)2C4O2Co(P(C6H5)3)2Cl

: 95-45-4
butane-2,3-dione dioxime

: (CH3)2C4(O)2 cobalt(triphenylphoshine)(dimethylglyoxime)(chloride)

Conditions

Conditions	Yield
In acetonitrile 24 h/room temp.;;	90%
In acetonitrile	90%

: 7647-01-0
hydrogenchloride

: cobalt(II) chloride hexahydrate

: 95-45-4
butane-2,3-dione dioxime

: H{CoCl2(dmgH)2}

Conditions

Conditions	Yield
With perhydrol In water heating mixture of CoCl2*6H2O and powdered dimethylglyoxime in H2O on a water-bath; addn. of perhydrol under stirring; addn. of excess HCl-soln. to the warm soln.;; washing with dild. HCl-soln., alcohol and ether;;	90%

...Expand

: chloropentaamminerhodium(III) chloride

: 95-45-4
butane-2,3-dione dioxime

: diamminebis(dimethylglyoxime)rhodium(III) chloride pentahydrate

Conditions

Conditions	Yield
With ammonium acetate In water heating all compounds in a sealed tube (10 hours/150 °C);; filtration; evapn. of the filtrate to dryness; washing (alc.); recrystn. from hot water;;	90%

: 108-99-6
3-Methylpyridine

: cobalt bromide hexahydrate

: 13465-09-3
indium tribromide

: 95-45-4
butane-2,3-dione dioxime

: {Co(3-picoline)2(MeC(NOH)C(NO)Me)2}{InBr4}

Conditions

Conditions	Yield
In methanol addn. of CoCl26H2O in MeOH to dimethylglyoxime, heating (water bath), addn. of pyridine and MeOH soln. of InCl33H2O (ratio of Co/dioxime/In/amine 1:2:1:5, stirring), heating (stirring until substances dissolved); crystn. on cooling, filtration off, washing (MeOH, ether), drying (air); elem. anal.;	90%

...Expand

Dimethylglyoxime Chemical Properties

IUPAC Name: N-[(Z)-3-nitrosobut-2-en-2-yl]hydroxylamine
Molecular formula: C₄H₈N₂O₂
Molar mass: 116.12 g/mol
Appearance: White/Off White Powder
Index of Refraction: 1.487
Molar Refractivity: 28.417 cm³
Molar Volume: 98.819 cm³
Polarizability: 11.265× 10^-24cm³
Surface Tension: 37.538 dyne/cm
Density: 1.175 g/cm³
Flash Point: 158.376 °C
Enthalpy of Vaporization: 59.186 kJ/mol
Melting point: 240 - 241 °C
Boiling Point: 271.529 °C at 760 mmHg
Vapour Pressure: 0.001 mmHg at 25°C
Storage temp.: 2-8°C
Solubility in water: low
Stability: Stable. Incompatible with strong oxidizing agents.
Other names: Dimethylglyoxime,Diacetyl dioxime,Chugaev's Reagent 2,3-diisonitrosobutane
The Structure of Diacetyl dioxime (95-45-4):

Dimethylglyoxime Uses

Diacetyl dioxime (95-45-4) is used in the analysis of palladium or nickel.
Diacetyl dioxime (95-45-4) is used as a chelating agent in the gravimetric analysis of nickel.

Dimethylglyoxime Production

Diacetyl dioxime (95-45-4) can be prepared from butanone first by reaction with ethylnitrite followed by conversion of the biacetyl monoxime using sodium hydroxylamine monosulfonate:

Dimethylglyoxime Toxicity Data With Reference

1.		otr-ham:emb 100 µg/L		FCTXAV Food and Cosmetics Toxicology. 18 (1980),289.
2.		orl-rat LDLo:250 mg/kg		NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),26.

Dimethylglyoxime Consensus Reports

Reported in EPA TSCA Inventory.

Dimethylglyoxime Safety Profile

Poison by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: Xn
Risk Statements: 22-20/21/22
22: Harmful if swallowed
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements: 22-24/25-36
22: Do not breathe dust
24/25: Avoid contact with skin and eyes
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: EK2975000
F: 10: Keep under argon.
Hazard Note: Harmful
HS Code: 29280090

Dimethylglyoxime Specification

1. First Aid Measures
Ingestion:
Induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
2. Handling and Storage
Storage:
Keep away from heat and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Product Name

Dimethylglyoxime

Synthetic route

Dimethylglyoxime Chemical Properties

Dimethylglyoxime Uses

Dimethylglyoxime Production

Dimethylglyoxime Toxicity Data With Reference

Dimethylglyoxime Consensus Reports

Dimethylglyoxime Safety Profile

Dimethylglyoxime Specification

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