Product Name

  • Name

    Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide

  • EINECS 278-355-8
  • CAS No. 75980-60-8
  • Article Data36
  • CAS DataBase
  • Density 1.17 g/cm3
  • Solubility 3.4mg/L at 20℃
  • Melting Point 88-92 °C
  • Formula C22H21O2P
  • Boiling Point 519.6 °C at 760 mmHg
  • Molecular Weight 348.381
  • Flash Point 268.1 °C
  • Transport Information
  • Appearance white or cream powder
  • Safety 22-24/25
  • Risk Codes 22
  • Molecular Structure Molecular Structure of 75980-60-8 (Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide)
  • Hazard Symbols HarmfulXn
  • Synonyms TPO;Methanone,(diphenylphosphinyl)(2,4,6-trimethylphenyl)-;
  • PSA 43.95000
  • LogP 4.76610

Synthetic route

α-hydroxy-(2,4,6-trimethylbenzyl)diphenyl phosphine oxide

α-hydroxy-(2,4,6-trimethylbenzyl)diphenyl phosphine oxide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
With manganese(IV) oxide In dichloromethane at 20℃;98%
With vanadium(V) oxide; dihydrogen peroxide at 8 - 25℃; for 3.5h; Reagent/catalyst; Green chemistry;96%
With tert.-butylhydroperoxide In dichloromethane at 5 - 20℃; for 6.5h; Reagent/catalyst;92.5%
mesytaldehyde
487-68-3

mesytaldehyde

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: mesytaldehyde; Diphenylphosphine oxide In dichloromethane for 6h; Green chemistry;
Stage #2: With ammonium metavanadate; dihydrogen peroxide at 8 - 20℃; for 5.5h; Reagent/catalyst; Green chemistry;
98%
diphenyl n-pentyloxyphosphine
39150-04-4

diphenyl n-pentyloxyphosphine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 50 - 90℃; for 9.33333h;95.8%
(sec-butyloxy)di(phenyl)phosphine
65119-90-6

(sec-butyloxy)di(phenyl)phosphine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 50 - 90℃; for 7.33333h;95.6%
Ethyl diphenylphosphinite
719-80-2

Ethyl diphenylphosphinite

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 40 - 90℃; for 8h; Time; Green chemistry;95.1%
With N,N-dimethyl-cyclohexanamine at 80 - 85℃; Product distribution / selectivity;
diphenyl n-propoxyphosphine
92556-46-2

diphenyl n-propoxyphosphine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 50 - 90℃; for 7.33333h;95.1%
diphenyl sec-pentyloxyphosphine
38011-61-9

diphenyl sec-pentyloxyphosphine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 50 - 90℃; for 7.33333h;94.9%
(n-butyloxy)di(phenyl)phosphine
13360-94-6

(n-butyloxy)di(phenyl)phosphine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 50 - 90℃; for 9.33333h;94.8%
(2,4,6-trimethylbenzyl)diphenylphosphine oxide
149731-53-3

(2,4,6-trimethylbenzyl)diphenylphosphine oxide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
With tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium In dichloromethane at 20℃;94%
ethanol
64-17-5

ethanol

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: ethanol With sodium In toluene at 65 - 70℃; for 2h;
Stage #2: chloro-diphenylphosphine In toluene at 5 - 10℃; for 1h;
Stage #3: mesitylene-2-carboxylic acid chloride In toluene at 70 - 75℃; for 5h; Temperature; Solvent;
92.2%
(trichloromethyl)mesitylene
707-74-4

(trichloromethyl)mesitylene

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: chloro-diphenylphosphine With potassium hydroxide In toluene at 20℃; for 2.5h; Inert atmosphere;
Stage #2: (trichloromethyl)mesitylene With iron(III) chloride at 90℃; Inert atmosphere;
91%
Stage #1: (trichloromethyl)mesitylene; chloro-diphenylphosphine With magnesium In tetrahydrofuran Reflux;
Stage #2: With hydrogenchloride; dihydrogen peroxide In water
87 g
isopropyl diphenylphosphinite
27350-46-5

isopropyl diphenylphosphinite

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
at 50 - 90℃; for 7.33333h;90.7%
(trichloromethyl)mesitylene
707-74-4

(trichloromethyl)mesitylene

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: (trichloromethyl)mesitylene; Diphenylphosphine oxide With iron(III) chloride In toluene at 90℃; for 3h; Inert atmosphere;
Stage #2: With water; sodium hydrogencarbonate In toluene at 20℃; Inert atmosphere;
89%
Stage #1: Diphenylphosphine oxide With n-butyllithium In tetrahydrofuran for 0.5h; Cooling with ice;
Stage #2: (trichloromethyl)mesitylene In tetrahydrofuran for 0.5h;
87%
Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

A

C34H32O3P2

C34H32O3P2

B

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
With potassium hydroxide In 1,2-dichloro-ethane at -10℃; Solvent; Reagent/catalyst; Temperature; Inert atmosphere;A 8%
B 89%
Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
With dmap at 80℃;88.2%
With Methyltrichlorosilane; triethylamine In 1,4-dioxane at 60℃; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Schlenk technique; Inert atmosphere; Green chemistry;71%
Stage #1: mesitylene-2-carboxylic acid chloride With aluminum (III) chloride In 1,2-dichloro-ethane at 20℃; for 1h; Inert atmosphere;
Stage #2: Diphenylphosphine oxide In 1,2-dichloro-ethane for 5h; Reflux;
1.6 g
C22H21Cl2P

C22H21Cl2P

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
With dihydrogen peroxide In toluene84%
tetrachloromethane
56-23-5

tetrachloromethane

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: tetrachloromethane; 1,3,5-trimethyl-benzene With aluminum (III) chloride at 40℃; for 3.25h; Inert atmosphere;
Stage #2: With hydrogenchloride; water at 20℃; for 0.5h; Inert atmosphere;
Stage #3: Diphenylphosphine oxide In toluene Reagent/catalyst; Inert atmosphere;
84%
diphenylphosphinous acid methyl ester
4020-99-9

diphenylphosphinous acid methyl ester

2,2,2-trichloro-1-(2,4,6-trimethylphenyl)ethan-1-one
81759-79-7

2,2,2-trichloro-1-(2,4,6-trimethylphenyl)ethan-1-one

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
In toluene at 40 - 60℃;82%
Ethyl diphenylphosphinite
719-80-2

Ethyl diphenylphosphinite

2,2,2-trichloro-1-(2,4,6-trimethylphenyl)ethan-1-one
81759-79-7

2,2,2-trichloro-1-(2,4,6-trimethylphenyl)ethan-1-one

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
In toluene at 40 - 60℃;81%
tetrachloromethane
56-23-5

tetrachloromethane

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: tetrachloromethane; 1,3,5-trimethyl-benzene With aluminum (III) chloride at 40℃; for 3.25h; Inert atmosphere;
Stage #2: With hydrogenchloride; water at 20℃; for 0.5h; Inert atmosphere;
Stage #3: chloro-diphenylphosphine Further stages;
81%
mesytaldehyde
487-68-3

mesytaldehyde

benzene
71-43-2

benzene

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: benzene With aluminum (III) chloride; phosphorus trichloride at 70 - 120℃;
Stage #2: mesytaldehyde at 5 - 10℃;
Stage #3: With tungsten trioxide; tetrabutylammomium bromide; dihydrogen peroxide; sodium hydroxide at 5 - 10℃; pH=2;
80%
1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aluminum (III) chloride; hydrogenchloride / 2 h / 20 °C
2: magnesium / tetrahydrofuran / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / 3 h / 20 - 45 °C
2.1: n-butyllithium / tetrahydrofuran / 0.5 h / Cooling with ice
2.2: 0.5 h
View Scheme
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / 3 h / 20 - 45 °C
2.1: lithium / tetrahydrofuran / 35 °C / Inert atmosphere
2.2: 20 °C
3.1: dihydrogen peroxide / toluene
View Scheme
Multi-step reaction with 2 steps
1.1: C8H15N2(1+)*Br(1-)*2AlCl3; titanium tetrachloride; 1-methylimidazole hydrogen sulfate / 20 °C / 22502.3 - 30003 Torr / Autoclave
2.1: water; chlorobenzene / 2 h / 5 - 20 °C
2.2: 20 h / 5 °C / pH 3
View Scheme
(trichloromethyl)mesitylene
707-74-4

(trichloromethyl)mesitylene

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: lithium / tetrahydrofuran / 35 °C / Inert atmosphere
1.2: 20 °C
2.1: dihydrogen peroxide / toluene
View Scheme
2,4,6-trimethylbenzyl alcohol
4170-90-5

2,4,6-trimethylbenzyl alcohol

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dipotassium peroxodisulfate / acetone / 20 °C
2: manganese(IV) oxide / dichloromethane / 20 °C
View Scheme
mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

diphenyl(methyl)phosphine oxide
2129-89-7

diphenyl(methyl)phosphine oxide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
In toluene at 0 - 80℃; for 3h; Inert atmosphere;
In toluene at 0 - 80℃; for 3h; Inert atmosphere;
benzene
71-43-2

benzene

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aluminum (III) chloride; trichlorophosphate / 4 h / 70 °C / Inert atmosphere
2: dmap / 80 °C
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride; trichlorophosphate / 70 - 120 °C
1.2: 0.5 h / 30 °C
2.1: toluene / 40 - 60 °C
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride; trichlorophosphate / 70 - 130 °C
1.2: 0.5 h / 30 °C
2.1: toluene / 40 - 60 °C
View Scheme
diphenylphosphanyl(2,4,6-trimethylphenyl)methanone

diphenylphosphanyl(2,4,6-trimethylphenyl)methanone

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
With dihydrogen peroxide In diethyl ether at 30 - 45℃; for 2h; Inert atmosphere;59.3g
With tert.-butylhydroperoxide; vanadia In chlorobenzene at 30℃; under 1500.15 Torr; for 0.00138889h; Temperature; Reagent/catalyst;
With 3-chloro-benzenecarboperoxoic acid In tetrahydrofuran at 25℃; for 3h; Inert atmosphere;
chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-methyl-1H-imidazole / 2 h / 35 - 60 °C
2: 7.33 h / 50 - 90 °C
View Scheme
Multi-step reaction with 2 steps
1: 1-methyl-1H-imidazole / 2 h / 45 - 65 °C
2: 9.33 h / 50 - 90 °C
View Scheme
Multi-step reaction with 2 steps
1: 1-methyl-1H-imidazole / 2 h / 50 - 100 °C
2: 7.33 h / 50 - 90 °C
View Scheme
Multi-step reaction with 2 steps
1: 1-methyl-1H-imidazole / 2 h / 50 - 65 °C
2: 7.33 h / 50 - 90 °C
View Scheme
Multi-step reaction with 2 steps
1: 1-methyl-1H-imidazole / 3 h / 50 - 80 °C
2: 9.33 h / 50 - 90 °C
View Scheme
mesytaldehyde
487-68-3

mesytaldehyde

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: chlorobenzene / 0 h / 30 °C / 1500.15 Torr
2: vanadia; tert.-butylhydroperoxide / chlorobenzene / 0 h / 30 °C / 1500.15 Torr
View Scheme
Stage #1: mesytaldehyde; chloro-diphenylphosphine In water; chlorobenzene at 5 - 20℃; for 2h;
Stage #2: With ammonium molibdate; tetrabutylammomium bromide; dihydrogen peroxide; sodium hydroxide In water; chlorobenzene at 5℃; for 20h; pH=3;
(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

C25H24ClO3P

C25H24ClO3P

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 10 - 35℃; for 7h;99%
1-iodoperfluorododecane
307-60-8

1-iodoperfluorododecane

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

pentacosafluorododecyldiphenylphosphine
1424373-37-4

pentacosafluorododecyldiphenylphosphine

Conditions
ConditionsYield
With Diphenylphosphine oxide at 20℃; for 6h; Inert atmosphere; Irradiation;98%
(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

diphenyl(2,4,6-trimethylphenyl)phosphine oxide
91239-43-9

diphenyl(2,4,6-trimethylphenyl)phosphine oxide

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tricyclohexylphosphine In 5,5-dimethyl-1,3-cyclohexadiene at 130℃; for 16h; Schlenk technique; Inert atmosphere;97%
1-Iodo-perfluorodecane
423-62-1

1-Iodo-perfluorodecane

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

henicosafluorodecyldiphenylphosphine

henicosafluorodecyldiphenylphosphine

Conditions
ConditionsYield
With Diphenylphosphine oxide at 20℃; for 1.5h; Wavelength; Reagent/catalyst; Time; Inert atmosphere; Irradiation;96%
With diphenylphosphane at 20℃; for 3.5h; Wavelength; Irradiation; Inert atmosphere; Sealed tube;81 %Spectr.
In chloroform-d1 at 15 - 25℃; for 3.5h; Solvent; Irradiation; Sealed tube;41 %Spectr.
dodecafluoro-1,6-diiodohexane
375-80-4

dodecafluoro-1,6-diiodohexane

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

1,6-bis(diphenylthiophosphinyl)perfluorohexane
1424373-26-1

1,6-bis(diphenylthiophosphinyl)perfluorohexane

Conditions
ConditionsYield
Stage #1: dodecafluoro-1,6-diiodohexane; (2,4,6-trimethylbenzoyl)diphenylphosphine oxide With Diphenylphosphine oxide at 20℃; for 6h; Inert atmosphere; Irradiation;
Stage #2: With sulfur at 80℃; for 5h; Inert atmosphere;
96%
4,4'-dimethoxyphenyl disulfide
5335-87-5

4,4'-dimethoxyphenyl disulfide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

A

S-(4-methoxyphenyl) 2,4,6-trimethylthiobenzoate

S-(4-methoxyphenyl) 2,4,6-trimethylthiobenzoate

B

S-(4-methoxyphenyl)thiodiphenylphosphorus oxide
99234-85-2

S-(4-methoxyphenyl)thiodiphenylphosphorus oxide

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 87%
B 96%
(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

diphenyldisulfane
882-33-7

diphenyldisulfane

A

S-phenyl 2,4,6-trimethylthiobenzoate
50404-53-0

S-phenyl 2,4,6-trimethylthiobenzoate

B

diphenylthiophosphinic acid-S-phenyl ester
5510-78-1

diphenylthiophosphinic acid-S-phenyl ester

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 78%
B 95%
1-Iodo-perfluorodecane
423-62-1

1-Iodo-perfluorodecane

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

diphenylphosphane
829-85-6

diphenylphosphane

henicosafluorodecyldiphenylphosphine

henicosafluorodecyldiphenylphosphine

Conditions
ConditionsYield
at 20℃; for 1.5h; Irradiation;95%
In chloroform-d1 at 15 - 25℃; for 1.5h; Irradiation; Sealed tube;88%
di(p-tolyl) disulfide
103-19-5

di(p-tolyl) disulfide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

A

S-(4-methylphenyl)thiodiphenylphosphorus oxide
5510-81-6

S-(4-methylphenyl)thiodiphenylphosphorus oxide

B

S-(4-methylphenyl) 2,4,6-trimethylthiobenzoate

S-(4-methylphenyl) 2,4,6-trimethylthiobenzoate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 94%
B 94%
bis(p-chlorophenyl) diselenide
20541-49-5

bis(p-chlorophenyl) diselenide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

A

Se-(4-chlorophenyl) 2,4,6-trimethylselenobenzoate

Se-(4-chlorophenyl) 2,4,6-trimethylselenobenzoate

B

Se-(4-chlorophenyl) diphenylselenophosphinate

Se-(4-chlorophenyl) diphenylselenophosphinate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 94%
B 92%
dibutyl diselenide
20333-40-8

dibutyl diselenide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

A

P,P-diphenylphosphinoselenoic acid Se-butyl ester

P,P-diphenylphosphinoselenoic acid Se-butyl ester

B

Se-(n-butyl) 2,4,6-trimethylselenobenzoate

Se-(n-butyl) 2,4,6-trimethylselenobenzoate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 91%
B 94%
diphenyl diselenide
1666-13-3

diphenyl diselenide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

A

Se-phenyl diphenylselenophosphinate
2049-62-9

Se-phenyl diphenylselenophosphinate

B

Se-phenyl 2,4,6-trimethylselenobenzoate

Se-phenyl 2,4,6-trimethylselenobenzoate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 92%
B 88%
(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

chloroacetyl chloride
79-04-9

chloroacetyl chloride

C24H22ClO3P

C24H22ClO3P

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 10 - 35℃; for 7h;92%
dibenzyl disulphide
150-60-7

dibenzyl disulphide

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

A

diphenylphosphinothioic acid S-benzyl ester
3096-05-7

diphenylphosphinothioic acid S-benzyl ester

B

C17H18OS

C17H18OS

Conditions
ConditionsYield
In dichloromethane at 20℃; for 6h; Inert atmosphere; Sealed tube; Irradiation;A 91%
B 40 %Spectr.
1-Iodo-perfluorodecane
423-62-1

1-Iodo-perfluorodecane

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide
75980-60-8

(2,4,6-trimethylbenzoyl)diphenylphosphine oxide

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

henicosafluorodecyldiphenylphosphine

henicosafluorodecyldiphenylphosphine

Conditions
ConditionsYield
at 20℃; for 1.5h; Irradiation;90%
In chloroform-d1 at 15 - 25℃; for 1.5h; Irradiation;90%

Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide Chemical Properties

IUPAC Name: Diphenylphosphoryl-(2,4,6-trimethylphenyl)methanone 
Following is the structure of 2,4,6-Trimethylbenzoyldiphenylphosphine Oxide (CAS NO.75980-60-8):
                    
Molecular formula: C22H21O2P
Molecular Weight: 348.37 g/mol
EINECS: 278-355-8
Index of Refraction: 1.6
Molar Refractivity: 101.52 cm3
Molar Volume: 296.6 cm3
Density: 1.17 g/cm3
Flash Point: 268.1 °C 
Melting point: 88-92 °C(lit.)
Surface Tension: 48.4 dyne/cm
Enthalpy of Vaporization: 79.24 kJ/mol
Boiling Point: 519.6 °C at 760 mmHg
Vapour Pressure: 6.71E-11 mmHg at 25°C 
Product Categories of 2,4,6-Trimethylbenzoyldiphenylphosphine Oxide (CAS NO.75980-60-8): Functional Materials; Photopolymerization Initiators; Miscellaneous; Organic Photoinitiators; Polymerization Initiators
Stability of 2,4,6-Trimethylbenzoyldiphenylphosphine Oxide (CAS NO.75980-60-8): Stable. Incompatible with strong oxidizing agents.
Appearance of 2,4,6-Trimethylbenzoyldiphenylphosphine Oxide (CAS NO.75980-60-8): white or cream powder
Canonical SMILES: CC1=CC(=C(C(=C1)C)C(=O)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C
InChI: InChI=1S/C22H21O2P/c1-16-14-17(2)21(18(3)15-16)22(23)25(24,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-15H,1-3H3
InChIKey: VFHVQBAGLAREND-UHFFFAOYSA-N

Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide Safety Profile

Hazard Codes:  Xn
The Risk Statements information: 22
22:  Harmful if swallowed 
The Safety Statements information: 22-24/25
22:  Harmful if swallowed 
24/25:  Avoid contact with skin and eyes 
WGK Germany:2

Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide Specification

 2,4,6-Trimethylbenzoyldiphenylphosphine Oxide , its cas register number is 75980-60-8. It also can be called  Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide . Its classification code is TSCA Flag P [A commenced PMN (Premanufacture Notice) substance].

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