Ethoxyamine Hydrochloride supplier

Name
Ethoxyamine hydrochloride
EINECS 222-060-9
CAS No. 3332-29-4
Article Data14
CAS DataBase
Density
Solubility Soluble in water
Melting Point 130-133 °C(lit.)
Formula C₂H₇ NO.ClH
Boiling Point 75.8 °C at 760 mmHg
Molecular Weight 97.5446
Flash Point 5.9 °C
Transport Information
Appearance white adhering crystals or crystalline powder
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Ethoxyamine,hydrochloride (6CI,7CI);Hydroxylamine, O-ethyl-, hydrochloride (8CI,9CI);(Aminooxy)ethane hydrochloride;Ethoxamine hydrochloride;Ethoxyammoniumchloride;N-Ethoxyamine hydrochloride;O-Ethylhydroxylamine hydrochloride;
PSA 46.53000
LogP 2.43540

Synthetic route

: 1914-21-2
N-ethoxyphthalimide

: 3332-29-4
O-ethylhydroxylamine hydrochloride

Conditions

Conditions	Yield
Stage #1: N-ethoxyphthalimide With methylhydrazine In dichloromethane at 0 - 20℃; for 2h; Stage #2: With hydrogenchloride In 1,4-dioxane at 0℃;	100%
With hydrogenchloride; hydrazine hydrate 1.) ethanol, reflux, 20 min; 2.) ethanol, reflux, 20 min; Yield given. Multistep reaction;
With methylhydrazine In dichloromethane

: 52914-24-6
ethyl acetohydroxamate

: 3332-29-4
O-ethylhydroxylamine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol; water at 65℃;	71.2%
With hydrogenchloride In ethanol; water at 65℃;	71.2%

: 22509-51-9
O-ethyl benzoylhydroxamic acid

: 3332-29-4
O-ethylhydroxylamine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol Heating;	48%

: 1-ethoxy-pyrrolidine-2,5-dione

: 3332-29-4
O-ethylhydroxylamine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride

: 624-86-2
O-ethyl hydroxylamine

: 3332-29-4
O-ethylhydroxylamine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol at 0 - 5℃; for 72h;
With hydrogenchloride Large scale;	7.2 kg

: 121-32-4
4-hydroxy-3-ethoxybenzaldehyde

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 3-ethoxy-4-hydroxybenzaldehyde-O-ethyloxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	100%

: 2233-18-3
4-hydroxy-3,5-dimethylbenzaldehyde

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 3,5-dimethyl-4-hydroxybenzaldehyde-O-ethyloxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	100%

: 13677-79-7
gallaldehyde

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 3,4,5-trihydroxybenzaldehyde-O-ethyloxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	100%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 139-85-5
3,4-dihydroxybenzaldehyde

: 3,4-dihydroxybenzaldehyde-O-ethyloxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	100%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 23611-75-8
6-chloro-pyrazine-2-carboxylic acid methyl ester

: 6-chloro-N-ethoxypyrazine-2-carboxamide

Conditions

Conditions	Yield
With trimethylaluminum In hexane; dichloromethane at 20℃; Inert atmosphere;	100%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 70-70-2
4-hydroxypropiophenone

: (E)-1-(4-hydroxyphenyl)propan-1-one-O-ethylketoxime

Conditions

Conditions	Yield
With sodium acetate In ethanol at 80℃; for 4h;	99%
With sodium acetate at 80℃; for 2h;

: 93457-07-9
1-(2,4-dichlorophenyl)-propan-2-one

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 1228284-91-0
1-(2,4-dichlorophenyl)-propan-2-one O-ethyl-oxime

Conditions

Conditions	Yield
With sodium acetate In tetrahydrofuran; water at 23℃; for 4h;	99%
With sodium acetate In tetrahydrofuran; water at 23℃; for 4h;

: 31191-08-9
5-hydroxy-2-pyridinecarboxaldehyde

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: (E)-5-hydroxypyridinecarboxaldehyde-O-ethylketoxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	99%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 108-94-1
cyclohexanone

: 3376-38-3
cyclohexanone O-ethyl oxime

Conditions

Conditions	Yield
With sodium acetate In ethanol; water at 75℃; for 3h;	99%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 120-92-3
cyclopentanone

: 31376-96-2
cyclopentanone O-ethyl oxime

Conditions

Conditions	Yield
With sodium acetate In ethanol; water at 75℃; for 3h;	99%
With sodium acetate In ethanol; water at 65℃; for 3h;	40%

: 621-59-0
isovanillin

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 3-hydroxy-4-methoxybenzaldehyde-O-ethyloxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	98%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 10200-03-0, 83946-65-0, 83946-66-1, 109211-48-5
photoprotoporphyrin IX dimethyl ester

: 3-ethenyl-7-hydroxyl-8-ethoxyiminoethylidene-2,7,12,18-tetramethylporphyrin-13,17-dipropionic acid dimethyl ester

Conditions

Conditions	Yield
In pyridine at 20℃; for 1h;	98%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: N-ethoxy-3-(8-ethyl-2-methylsulfanyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-6-yl)-5-methoxy-benzamide

Conditions

Conditions	Yield
Stage #1: 3-(8-ethyl-2-methylsulfanyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-6-yl)-5-methoxy-benzoic acid With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 0℃; for 0.25h; Stage #2: O-ethylhydroxylamine hydrochloride In N,N-dimethyl-formamide at 20℃; for 1h; Stage #3: With sodium carbonate In water	97%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 65-46-3
CYTIDINE

: 1228271-25-7
N4-ethoxycytidine

Conditions

Conditions	Yield
With pyridine at 100℃;	97%

: 145-13-1
Pregnenolone

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: (E)-1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone O-ethyl oxime

Conditions

Conditions	Yield
With pyridine at 95℃; for 0.3h; Inert atmosphere;	97%
With pyridine at 95℃; for 18h; Inert atmosphere;	97%
With pyridine at 95℃; for 18h; Inert atmosphere;	97%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 100-52-7
benzaldehyde

: 13858-87-2
O-ethyl benzaldehyde oxime

Conditions

Conditions	Yield
With sodium carbonate; acetic acid In methanol; water for 2h; Heating;	96%
With hydrogenchloride In ethanol; water Reflux;	57%

: 24677-78-9
2,3-dihydroxybenzaldehyde

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 2,3-dihydroxybenzaldehyde-O-ethyloxime

Conditions

Conditions	Yield
With sodium acetate In water at 80℃; for 2h;	96%

: 951152-69-5
4-amino-6-(4-fluoro-2-methyl-1H-indol-5-yloxy)-pyrimidine-5-carbaldehyde

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 4-amino-6-(4-fluoro-2-methyl-1H-indol-5-yloxy)-pyrimidine-5-carbaldehyde O-ethyl-oxime

Conditions

Conditions	Yield
In dimethyl sulfoxide at 20℃; for 2h;	96%

: C26H30N2O2

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: C28H35N3O2

Conditions

Conditions	Yield
Stage #1: C26H30N2O2; O-ethylhydroxylamine hydrochloride With pyridine at 40℃; for 4h; Inert atmosphere; Stage #2: Inert atmosphere;	96%

: 181697-00-7
1-(4-methylthiophenyl)-2-butanone

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 1204749-72-3
2-N-ethoxyimino-1-(4-methylthiophenyl)butane

Conditions

Conditions	Yield
With pyridine In ethanol for 2h; Reflux;	96%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 600178-09-4
3,3:17,17-bis(ethylendioxy)androstane-6-one

: 953772-35-5
3,3:17,17-bis(ethylendioxy)-6-[(E)-ethoxyimino]androstane

Conditions

Conditions	Yield
With sodium phosphate dibasic dodecahydrate In tetrahydrofuran; water at 20℃;	96%

: 1446092-98-3
C31H44O7

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: ((2R,3S)-3-acetoxy-6-((3S,10R,13S,17S)-17-((E)-1-(ethoxyimino)ethyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxy)-3,6-dihydro-2H-pyran-2-yl)methyl acetate

Conditions

Conditions	Yield
With pyridine for 3h; Reflux;	96%

: 1446092-98-3
C31H44O7

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: C33H49NO7

Conditions

Conditions	Yield
With pyridine at 80℃; for 4h; Inert atmosphere;	96%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 638-29-9
n-valeryl chloride

: N-ethoxypentanoamide

Conditions

Conditions	Yield
With sodium hydroxide In dichloromethane; water at 10 - 40℃;	95.8%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 2458-05-1
3-methyl-2-methylsulfanyl-6-nitro-benzothiazolium; methyl sulfate

: 3-methyl-6-nitro-3H-benzothiazol-2-one O-ethyl-oxime

Conditions

Conditions	Yield
With pyridine at 65℃; for 20h;	95%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 3-ethyl-2-methylsulfanyl-6-nitro-benzothiazolium; ethyl sulfate

: 3-ethyl-6-nitro-3H-benzothiazol-2-one O-ethyl-oxime

Conditions

Conditions	Yield
With pyridine at 65℃; for 20h;	95%

: C5H3Cl2NOS

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: C6H6Cl2N2OS

Conditions

Conditions	Yield
With triethylamine In ethanol at 20℃; for 1h;	95%

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 79-03-8
propionyl chloride

: 91521-43-6
ethyl propionohydroxamate

Conditions

Conditions	Yield
With sodium hydroxide In dichloromethane at 10 - 40℃;	94.9%

: 88633-19-6
3-hydroxy-5-(5-indanyl)-2-propionylcyclohex-2-en-1-one

: 3332-29-4
O-ethylhydroxylamine hydrochloride

A: 2-[1-(Ethoxyimino)propyl]-3-hydroxy-5-(5-indanyl)cyclohex-2en-1-one

B: 88632-13-7
2-[1-(ethoxyimino)propyl]-3-hydroxy-5(5-indanyl)-cyclohex-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; dichloromethane	A n/a B 94.8%

...Expand

Ethoxyamine Hydrochloride Specification

The Ethoxyamine Hydrochloride, with the CAS registry number 3332-29-4, has the IUPAC name of O-ethylhydroxylamine hydrochloride. For being a kind of white or light yellow crystal, it is soluble in water and ethanol, with the product categories including pharmaceutical intermediates.

The physical properties of this chemical are as follows: (1)ACD/LogP: 0.30; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.15; (4)ACD/LogD (pH 7.4): 0.3; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 24.64; (8)ACD/KOC (pH 7.4): 34.62; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 12.47; (13)Flash Point: 5.9 °C; (14)Enthalpy of Vaporization: 31.69 kJ/mol; (15)Boiling Point: 75.8 °C at 760 mmHg; (16)Vapour Pressure: 104 mmHg at 25°C; (17)Exact Mass: 97.029442; (18)MonoIsotopic Mass: 97.029442; (19)Topological Polar Surface Area: 35.2; (20)Heavy Atom Count: 5; (21)Complexity: 10.

The production method of this chemical: ethyl acetate could react with hydroxylamine sulphate in presence of alkali to have one chemical; Next the chemical has the ethylation with ethyl sulfate and then react in muriatic acid to get this product.

As to its usage, it is widely applied in many ways. It could be used as the intermediates of cycloxydim; It could also be producing a variety of herbicide, and then as a kind of important pesticide.

Additionally, you could obtain the molecular structure by converting the following datas:
(1)Canonical SMILES: CCON.Cl
(2)InChI: InChI=1S/C2H7NO.ClH/c1-2-4-3;/h2-3H2,1H3;1H
(3)InChIKey: NUXCOKIYARRTDC-UHFFFAOYSA-N

Product Name

Ethoxyamine hydrochloride

Synthetic route

Ethoxyamine Hydrochloride Specification

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