Product Name

  • Name

    Ethyl pyruvate

  • EINECS 210-511-2
  • CAS No. 617-35-6
  • Article Data127
  • CAS DataBase
  • Density 1.04 g/cm3
  • Solubility Miscible with water, ethanol and ether.
  • Melting Point -58 °C
  • Formula C5H8O3
  • Boiling Point 154.999 °C at 760 mmHg
  • Molecular Weight 116.117
  • Flash Point 45.556 °C
  • Transport Information UN 3272 3/PG 3
  • Appearance clear pale yellow liquid
  • Safety 16
  • Risk Codes 10
  • Molecular Structure Molecular Structure of 617-35-6 (Ethyl pyruvate)
  • Hazard Symbols IrritantXi, FlammableF
  • Synonyms Pyruvicacid, ethyl ester (6CI,7CI,8CI);2-Oxopropanoic acid ethyl ester;2-Oxopropionic acid ethyl ester;Ethyl 2-oxopropanoate;Ethyl 2-oxopropionate;Ethyl methylglyoxylate;NSC 48386;
  • PSA 43.37000
  • LogP 0.13850

Synthetic route

ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With dihydrogen peroxide at 50℃; for 7h; Catalytic behavior; Kinetics; Reagent/catalyst; Temperature; Heating;98.6%
With hydrogenchloride; zinc(II) nitrate; hydroxylamine hydrochloride; oxygen; copper(II) nitrate; sodium hydroxide at 100℃; under 75.0075 Torr; for 8h; Reagent/catalyst; Pressure; Temperature; Molecular sieve; Autoclave; Green chemistry;97.7%
With hydrogenchloride; sodium hypobromide In dichloromethane; water at 25℃; for 5h;92%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With aluminum (III) chloride; Oxone In water at 20℃; for 0.166667h;98%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With aluminum (III) chloride; Oxone In water at 20℃; for 3h;98%
2-methyl-1,3-dithiolane-2-carboxylic acid ethyl ester
76339-59-8

2-methyl-1,3-dithiolane-2-carboxylic acid ethyl ester

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With trichloroisocyanuric acid; silver nitrate In water; acetonitrile Ambient temperature;95%
With fluorosulfonylchloride In diethyl ether; water Ambient temperature;73%
With t-butyl bromide; dimethyl sulfoxide at 70 - 75℃; for 24h;57%
ethanol
64-17-5

ethanol

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 2-oxo-propionic acid With oxalyl dichloride In dichloromethane for 4h; Reflux;
Stage #2: ethanol at 20℃;
92.8%
With tetrachloromethane
With benzene
methyl 2-hydroxy-3-phenylpropanoate
13674-16-3

methyl 2-hydroxy-3-phenylpropanoate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With VPO/Al2O3 catalyst In dimethyl sulfoxide at 100℃; under 7500.75 Torr; for 4h;90.2%
n-butyl lactate
138-22-7

n-butyl lactate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With oxalic acid diethyl ester at 130℃; under 760.051 Torr; for 5h; Reagent/catalyst; Temperature;90.2%
benzyl lactate
2051-96-9

benzyl lactate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With Diethyl glutarate at 120℃; under 15001.5 Torr; for 2h;90.1%
methyl lactate
547-64-8

methyl lactate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 130℃; under 760.051 Torr; for 6h;87.8%
ethyl acrylate
140-88-5

ethyl acrylate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With tert.-butylhydroperoxide; C21H19N5Pd(2+)*2BF4(1-) In decane; acetonitrile at 70℃; for 24h; Temperature; Wacker Oxidation;85%
ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

sodium sulfite
7757-83-7

sodium sulfite

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With dihydrogen peroxide; bromine In dichloromethane; water80.2%
methylmagnesium bromide
75-16-1

methylmagnesium bromide

ethyl 3,5-dimethyl-1-pyrazolylglyoxylate
220332-87-6

ethyl 3,5-dimethyl-1-pyrazolylglyoxylate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
In diethyl ether at -90℃; for 1h;69%
2-Benzenesulfonyl-2-methylsulfanyl-propionic acid ethyl ester
190672-16-3

2-Benzenesulfonyl-2-methylsulfanyl-propionic acid ethyl ester

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
at 150℃; under 7 Torr;68%
1-ethoxy-1-propyne
14273-06-4

1-ethoxy-1-propyne

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With iodosylbenzene; tris(triphenylphosphine)ruthenium(II) chloride In dichloromethane for 0.25h; Ambient temperature;67%
ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

methyl iodide
74-88-4

methyl iodide

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
Stage #1: ethyl (triphenylphosphoranylidene)acetate; methyl iodide With sodium hydroxide In dichloromethane at -60℃;
Stage #2: With dimethylsulfide; ozone
65%
Diethyl tartrate
408332-88-7

Diethyl tartrate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With potassium pyrosulfate; water; silica gel In benzene at 300℃; other compounds with glycol moieties; var. catalysts; var. temperatures;60%
Ac-Gly-Ala-OEt

Ac-Gly-Ala-OEt

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

Ac-NHCOCO-Ala-OEt

Ac-NHCOCO-Ala-OEt

Conditions
ConditionsYield
With peracetic acid; ruthenium trichloride In acetic acid; ethyl acetate at 20℃; for 4h;A 8 % Chromat.
B 60%
(S)-Ethyl lactate
687-47-8

(S)-Ethyl lactate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With 3-Methylpyridine; oxygen; succinic acid diethyl ester at 130℃; under 760.051 Torr; for 4h; Catalytic behavior; Kinetics; Reagent/catalyst;54%
With oxygen at 180℃; for 2h; Catalytic behavior; Activation energy; Mechanism; Reagent/catalyst; Temperature;37.4 %Chromat.
ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

Ph3Sb 26 percent

Ph3Sb 26 percent

Conditions
ConditionsYield
With triphenylantimony dibromide; 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane for 24h; Ambient temperature;A 46%
B n/a
bis(triphenylphosphoranilydene)ammonium ethyl oxalyl tetracarbonyl iron

bis(triphenylphosphoranilydene)ammonium ethyl oxalyl tetracarbonyl iron

methyltrifluoro methanesulfonate

methyltrifluoro methanesulfonate

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

(CO)4Fe(CH3)COCOOC2H5

(CO)4Fe(CH3)COCOOC2H5

cis-(CO)4Fe(COCH3)COOC2H5

cis-(CO)4Fe(COCH3)COOC2H5

trans-(CO)4Fe(COCH3)COOC2H5

trans-(CO)4Fe(COCH3)COOC2H5

Conditions
ConditionsYield
In dichloromethane-d2 -45°C, 6 h; monitored by (1)H- and (13)C-NMR;A <1
B 15%
C <1
D <1
pyridine
110-86-1

pyridine

tetrachloromethane
56-23-5

tetrachloromethane

N-Bromosuccinimide
128-08-5

N-Bromosuccinimide

ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

tetrachloromethane
56-23-5

tetrachloromethane

N-Bromosuccinimide
128-08-5

N-Bromosuccinimide

ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

ethyl Bromopyruvate
70-23-5

ethyl Bromopyruvate

tetrachloromethane
56-23-5

tetrachloromethane

N-Bromosuccinimide
128-08-5

N-Bromosuccinimide

methylglyoxal diethyl acetal
5774-26-5

methylglyoxal diethyl acetal

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

methylglyoxal diethyl acetal
5774-26-5

methylglyoxal diethyl acetal

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With tetrachloromethane; N-Bromosuccinimide
ethoxy-2-propanone
14869-34-2

ethoxy-2-propanone

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With manganese(II) nitrate; oxygen; acetic acid at 70 - 75℃;
2-trityloxy-propionic acid ethyl ester
123077-62-3

2-trityloxy-propionic acid ethyl ester

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

triphenylmethane
519-73-3

triphenylmethane

Conditions
ConditionsYield
at 300℃;
diethyl meso-2,5-dibromoadipate
54221-37-3

diethyl meso-2,5-dibromoadipate

diethylamine
109-89-7

diethylamine

benzene
71-43-2

benzene

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

ethyl 3-(diethylamino)propionate
5515-83-3

ethyl 3-(diethylamino)propionate

diethyl oxaloacetate
108-56-5

diethyl oxaloacetate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
rasche Destillation;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; oxalide-4; sodium chloride In water at 24.84℃; pH=7; Enzyme kinetics; Further Variations:; Reagents;
2,3-dimethyl-pentenedioic acid diethyl ester

2,3-dimethyl-pentenedioic acid diethyl ester

methyl iodide
74-88-4

methyl iodide

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

2-acetylpropanoic acid ethyl ester
609-14-3

2-acetylpropanoic acid ethyl ester

C

oxalic acid
144-62-7

oxalic acid

D

ethyl acetoacetate
141-97-9

ethyl acetoacetate

Conditions
ConditionsYield
das Silbersalz reagiert,bei der Ozonspaltung des erhaltenen Produktes;
3-methyl-1,4-benzoxazin-2-one
7653-60-3

3-methyl-1,4-benzoxazin-2-one

ethanol
64-17-5

ethanol

A

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

B

2-aminophenol hydrochloride
51-19-4

2-aminophenol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride for 0.25h; boiling water bath;
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

ethyl 2,2-diethoxypropionate
7476-20-2

ethyl 2,2-diethoxypropionate

Conditions
ConditionsYield
With sulfuric acid In ethanol100%
With sulfuric acid for 3h; Ambient temperature;98%
With sulfuric acid at 20℃; for 15h; Inert atmosphere;98%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

ethyl (2E)-2-(hydroxyimino)propanoate
250602-55-2

ethyl (2E)-2-(hydroxyimino)propanoate

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium acetate In methanol Reflux;100%
With hydroxylamine hydrochloride; sodium acetate In ethanol59%
With hydroxylamine hydrochloride
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

Conditions
ConditionsYield
With hydrogen at 20℃; under 15001.5 Torr; Reagent/catalyst;100%
With chloro(η6-p-cymene)(2-phenylbenzo[d]thiazole-κ-C,N)ruthenium(II); hydrogen In methanol; water at 80℃; under 3800.26 Torr; for 3h; Inert atmosphere; Schlenk technique; Autoclave;94%
With t-BuOSmI2; isopropyl alcohol In tetrahydrofuran at 65℃; for 24h; Product distribution;80%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

3-methyl-2-oxo-1,2-dihydroquinoxaline
14003-34-0

3-methyl-2-oxo-1,2-dihydroquinoxaline

Conditions
ConditionsYield
In ethanol for 4h; Heating;100%
In ethanol at 20℃; for 4h;100%
In butan-1-ol for 1h; Reflux;97%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

allyltributylstanane
24850-33-7

allyltributylstanane

Ethyl 2-Hydroxy-2-methyl-4-pentenoate
62696-37-1

Ethyl 2-Hydroxy-2-methyl-4-pentenoate

Conditions
ConditionsYield
With tin(ll) chloride In acetonitrile for 2h;100%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

(1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine
194233-66-4

(1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine

(E)-ethyl 6-(dimethylamino)-2-hydroxy-2-methyl-4-oxohex-5-enoate
1321937-21-6

(E)-ethyl 6-(dimethylamino)-2-hydroxy-2-methyl-4-oxohex-5-enoate

Conditions
ConditionsYield
With water at 20℃; for 1h; Mukaiyama reaction;100%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

(S)-Ethyl lactate
687-47-8

(S)-Ethyl lactate

Conditions
ConditionsYield
With hydrogen; Cinchonin In acetic acid at 25℃; under 7500.75 Torr; for 12h; Catalytic behavior; Pressure; Solvent; Time; Reagent/catalyst; enantioselective reaction;99.9%
In water keto reductase enzyme from bakers' yeast (YKER-I);79%
With Saccharomyces cerevisiae at 30℃; for 4h; pH=7; aq. buffer; optical yield given as %ee; enantioselective reaction;68%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

ethyl 2,2-difluoropropanoate
28781-85-3

ethyl 2,2-difluoropropanoate

Conditions
ConditionsYield
With (bis-(2-methoxyethyl)amino)sulfur trufluoride at -15 - 30℃;99.4%
With sulfur tetrafluoride In hydrogen fluoride at 20℃; for 12h; steel autoclave;78%
With diethylamino-sulfur trifluoride at 60℃; for 4h;62.3%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

N-methyl-2-(methylamino)benzamide
32212-33-2

N-methyl-2-(methylamino)benzamide

1,2,3,4-tetrahydro-1,2,3-trimethyl-4-oxoquinazoline-2-carboxylic acid ethyl ester
76562-81-7

1,2,3,4-tetrahydro-1,2,3-trimethyl-4-oxoquinazoline-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride In ethanol for 53h; Heating;99%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

2-Bromo-4'-methoxyacetophenone
2632-13-5

2-Bromo-4'-methoxyacetophenone

2-Hydroxy-4-(4-methoxy-phenyl)-2-methyl-4-oxo-butyric acid ethyl ester

2-Hydroxy-4-(4-methoxy-phenyl)-2-methyl-4-oxo-butyric acid ethyl ester

Conditions
ConditionsYield
With samarium diiodide In tetrahydrofuran Ambient temperature;99%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

diethyl 2-ethoxycarbonyl-3-methylbutadienoate
30313-07-6

diethyl 2-ethoxycarbonyl-3-methylbutadienoate

acetic anhydride
108-24-7

acetic anhydride

2-Acetoxy-3,3-bis-ethylsulfanylcarbonyl-2-methyl-propionic acid ethyl ester
191918-00-0

2-Acetoxy-3,3-bis-ethylsulfanylcarbonyl-2-methyl-propionic acid ethyl ester

Conditions
ConditionsYield
With zinc(II) chloride at 100℃;99%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

nitromethane
75-52-5

nitromethane

(-)-2-hydroxy-2-methyl-3-nitro-propionic acid ethyl ester

(-)-2-hydroxy-2-methyl-3-nitro-propionic acid ethyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; (CuOTf)2*C7H8 In tetrahydrofuran at -45℃; for 24h; Henry reaction;99%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

dimethyl 2,2-di(but-2-yn-1-yl)malonate
107428-05-7

dimethyl 2,2-di(but-2-yn-1-yl)malonate

3-acetyl-4-(2-ethoxycarbonyl-1-methylpropenyl)cyclopent-3-ene-1,1-dicarboxylic acid dimethyl ester

3-acetyl-4-(2-ethoxycarbonyl-1-methylpropenyl)cyclopent-3-ene-1,1-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; 2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; hydrogen In dichloromethane at 20℃; for 3h; Inert atmosphere; optical yield given as %de;99%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

(2-bromo-4-nitro-phenyl)-hydrazine
72790-96-6

(2-bromo-4-nitro-phenyl)-hydrazine

2-[(2-bromo-4-nitro-phenyl)-hydrazono]-propionic acid ethyl ester
1391602-17-7

2-[(2-bromo-4-nitro-phenyl)-hydrazono]-propionic acid ethyl ester

Conditions
ConditionsYield
In 1,4-dioxane at 20℃; for 2h;99%
In 1,4-dioxane at 20℃; for 2h;94%
In 1,4-dioxane at 20℃; for 0.5h;71%
In 1,4-dioxane at 20℃; for 0.5h;71%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

(2-methyl-4-nitro-phenyl)-hydrazine
77484-08-3

(2-methyl-4-nitro-phenyl)-hydrazine

2-<4-Nitro-2-methyl-phenylhydrazono>-propionsaeure-ethylester
93185-75-2

2-<4-Nitro-2-methyl-phenylhydrazono>-propionsaeure-ethylester

Conditions
ConditionsYield
In 1,4-dioxane at 20℃; for 1h;99%
In 1,4-dioxane at 20℃; for 1h;12.1 g
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

pyruvamide
631-66-3

pyruvamide

Conditions
ConditionsYield
With ammonia In methanol at 0℃; for 0.5h; Solvent;98.3%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

ethyl pyruvate oxime
120586-56-3, 20591-87-1

ethyl pyruvate oxime

Conditions
ConditionsYield
With hydroxylamine In ethanol; water at 23℃; for 12h; Inert atmosphere;98%
With hydroxylamine hydrochloride In water at 20℃; for 4h;88.6%
With hydroxylamine hydrochloride; sodium acetate In ethanol; water at 20℃; for 3h;84%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

1-hydrazino-5,6,7,8-tetrahydronaphthalene
85790-17-6

1-hydrazino-5,6,7,8-tetrahydronaphthalene

2-[(5,6,7,8-Tetrahydro-naphthalen-1-yl)-hydrazono]-propionic acid ethyl ester
110595-85-2

2-[(5,6,7,8-Tetrahydro-naphthalen-1-yl)-hydrazono]-propionic acid ethyl ester

Conditions
ConditionsYield
With potassium acetate In water at 40℃; for 1h;98%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

cyclopropyl(4-fluorophenyl)methanone
772-31-6

cyclopropyl(4-fluorophenyl)methanone

4-(4-fluorobenzoyl)-3-methyl-5,6-dihydropyran-2-one

4-(4-fluorobenzoyl)-3-methyl-5,6-dihydropyran-2-one

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In 1,2-dichloro-ethane at 60℃; for 10h;98%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

(2,4-dichlorophenyl)hydrazine
13123-92-7

(2,4-dichlorophenyl)hydrazine

ethyl 2-(2-(2,4-dichlorophenyl)hydrazono)propanoate
4792-68-1

ethyl 2-(2-(2,4-dichlorophenyl)hydrazono)propanoate

Conditions
ConditionsYield
With triethylamine In ethanol; chloroform98%
With triethylamine In ethanol98%
In ethanol; acetic acid17.0 g (83%)
With acetic acid In methanol
With trifluoroacetic acid In water at 20℃;
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

4-chloro-aniline
106-47-8

4-chloro-aniline

diethyl 6‐chloro‐2‐methyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate
1310688-84-6

diethyl 6‐chloro‐2‐methyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate

Conditions
ConditionsYield
With TiO2 nanoparticles In neat (no solvent) at 80℃; for 0.5h; Catalytic behavior; Green chemistry;98%
With iodine In acetonitrile at 50℃; for 16h; Temperature; Solvent; Reagent/catalyst;97%
With 3-(1,1-dioxido-4-(3-(3-(3-sulfopropyl)-1H-imidazol-3-ium-1-yl)propyl)thiomorpholino-4-ium)propane-1-sulfonate trifluoromethanesulfonate In acetic acid butyl ester at 80℃; for 3h; Reagent/catalyst; Solvent; Temperature; Time; Green chemistry;96%
With nitric acid In water; acetonitrile at 80℃; for 12h; Inert atmosphere;80%
With N-chloro-succinimide; O,O-bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrazine-1,2-bis(carbothioate) In acetonitrile at 60℃; Green chemistry;74%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

4-bromo-aniline
106-40-1

4-bromo-aniline

diethyl 6‐bromo‐2‐methyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate
1574699-77-6

diethyl 6‐bromo‐2‐methyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate

Conditions
ConditionsYield
With iodine In acetonitrile at 50℃; for 19h;98%
With TiO2 nanoparticles In neat (no solvent) at 80℃; for 0.75h; Green chemistry;98%
With 3-(1,1-dioxido-4-(3-(3-(3-sulfopropyl)-1H-imidazol-3-ium-1-yl)propyl)thiomorpholino-4-ium)propane-1-sulfonate trifluoromethanesulfonate In acetic acid butyl ester at 80℃; for 3h; Green chemistry;96%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

p-toluidine
106-49-0

p-toluidine

diethyl 2,6‐dimethyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate
1574699-83-4

diethyl 2,6‐dimethyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate

Conditions
ConditionsYield
With iodine In acetonitrile at 50℃; for 12h;98%
With TiO2 nanoparticles In neat (no solvent) at 80℃; for 1h; Green chemistry;98%
With bis(cyclopentadienyl)titanium dichloride; 4-sulfophthalic acid In water at 60℃; for 6h; Reagent/catalyst; Schlenk technique;90%
With 3-(1,1-dioxido-4-(3-(3-(3-sulfopropyl)-1H-imidazol-3-ium-1-yl)propyl)thiomorpholino-4-ium)propane-1-sulfonate trifluoromethanesulfonate In acetic acid butyl ester at 80℃; for 3h; Green chemistry;85%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

4-nitro-aniline
100-01-6

4-nitro-aniline

diethyl 2‐methyl‐6‐nitro‐1,2‐dihydroquinoline‐2,4‐dicarboxylate
1574699-89-0

diethyl 2‐methyl‐6‐nitro‐1,2‐dihydroquinoline‐2,4‐dicarboxylate

Conditions
ConditionsYield
With TiO2 nanoparticles In neat (no solvent) at 80℃; for 1h; Green chemistry;98%
With iodine In acetonitrile at 80℃; for 16h; Temperature;97%
With 3-(1,1-dioxido-4-(3-(3-(3-sulfopropyl)-1H-imidazol-3-ium-1-yl)propyl)thiomorpholino-4-ium)propane-1-sulfonate trifluoromethanesulfonate In acetic acid butyl ester at 80℃; for 3h; Green chemistry;87%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

4-chlorophenylhydrazine hydrochloride
1073-70-7

4-chlorophenylhydrazine hydrochloride

2-[(4-chlorophenyl)-hydrazono]-propionic acid ethyl ester
5296-86-6

2-[(4-chlorophenyl)-hydrazono]-propionic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 4-chlorophenylhydrazine hydrochloride In ethanol at 50℃; for 1h; Inert atmosphere;
Stage #2: 2-oxo-propionic acid ethyl ester In ethanol at 20 - 50℃; for 4h; Inert atmosphere;
98%
In ethanol; water at 80℃; for 3h; Fischer Indole Synthesis; Green chemistry;91%
In ethanol Reflux;
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

1-Amino-2-methylaminobenzimidazole
107879-46-9

1-Amino-2-methylaminobenzimidazole

1,2-dimethyl-1,2,4-triazino<2,3-a>benzimidazol-(4H)-3-one
120341-08-4

1,2-dimethyl-1,2,4-triazino<2,3-a>benzimidazol-(4H)-3-one

Conditions
ConditionsYield
In acetic acid for 3h; Heating;97%
2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

4,4'-dihydrazinodiphenyl sulfone
14052-65-4

4,4'-dihydrazinodiphenyl sulfone

ethyl pyruvate 4,4'-dihydrazonodiphenyl sulfone
77474-56-7

ethyl pyruvate 4,4'-dihydrazonodiphenyl sulfone

Conditions
ConditionsYield
With acetic acid In ethanol for 1h;97%

Ethyl pyruvate Chemical Properties

Product Name:Ethyl pyruvate
Synonyms:PAEE;RARECHEM AL BI 0116;PYRUVIC ACID ETHYL ESTER;PYR ET;ETHYL 2-OXOPROPIONATE;ETHYL 2-OXOPROPRIONATE;ETHYL 2-OXOPROPANOATE;ETHYL PYRUVATE EINECS: 210-511-2
Melting point:-58 °C 
Boiling point:144 °C(lit.)
density:1.045 g/mL at 25 °C(lit.)
refractive index:n20/D 1.404(lit.)
Flash point:114 °F

Ethyl pyruvate is the chemical compound with the formula C5H8O3 .Its molecular weight:116.12.It always is stored at 0-6°C .

Ethyl pyruvate Safety Profile

Ethyl pyruvate's Risk Statements:10:Flammable 
Ethyl pyruvate's Safety Statements:16:Keep away from sources of ignition - No smoking 
Hazard Codes:Xi,F
RIDADR:UN 3272 3/PG 3
WGK Germany:3
PackingGroup:III
HazardClass:3
Hazard Note:Flammable/Irritant

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