Gallic acid supplier | CasNO.149-91-7

Name
Gallic acid
EINECS 205-749-9
CAS No. 149-91-7
Article Data187
CAS DataBase
Density 1.749 g/cm³
Solubility 12 g/L in cold water
Melting Point 252 °C (dec.)(lit.)
Formula C₇H₆O₅
Boiling Point 501.1 °C at 760 mmHg
Molecular Weight 170.122
Flash Point 271 °C
Transport Information
Appearance white crystalline powder
Safety 24/25
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Kyselina gallova [Czech];Gallate;Pyrogallol-5-carboxylic acid;Benzoic acid, 3,4,5-trihydroxy-;3,4,5-Trihydroxybenzoic acid;Kyselina 3,4,5-trihydroxybenzoova [Czech];3,4,5-Trihydroxybenzoate;Gallic acid, tech.;Benzoic acid,3,4,5-trihydroxy-;
PSA 97.99000
LogP 0.50160

Synthetic route

: tannic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With water at 80℃; for 6h; Reagent/catalyst;	96.99%

: tannic acid

A: 2280-44-6
D-Glucose

B: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With water at 60℃; for 6h; Reagent/catalyst;	A n/a B 91.5%

: 118-41-2
Eudesmic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With pyridinium hydrobromide perbromide In xylene for 1.5h; Heating;	75%
With hydrogen iodide

: 2922-42-1
(-)-3-dehydroshikimic acid

A: 99-50-3
3,4-Dihydroxybenzoic acid

B: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With copper diacetate In water; acetic acid at 40℃; for 36h; Oxidation; aromatization;	A 0.7% B 62%
With copper diacetate; oxygen; zinc(II) oxide In acetic acid at 50℃; under 760.051 Torr; for 14h; Kinetics; Product distribution; Further Variations:; Reagents; Oxidation; aromatization;

: 71-23-8
propan-1-ol

: 99-24-1
methyl galloate

A: 121-79-9
Propyl gallate

B: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With tannase from Lactobacillus plantarum immobilised on glyoxyl-agarose at 25℃; pH=5; aq. acetate buffer; Enzymatic reaction;	A 55% B n/a

...Expand

: 13677-79-7
gallaldehyde

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium bromate; hydrogenchloride; potassium bromide In water for 12h; Time;	53%

: 555-44-2
glyceroltripalmitate

: 121-79-9
Propyl gallate

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 3-((3',4',5'-trihydroxybenzoyl)oxy)propane-1,2-diyl dipalmitate

Conditions

Conditions	Yield
With recombinant lipase B from Candida antarctica, expressed in Aspergillus niger, and immobilized on a macroporous hydrophobic resin In neat (no solvent) at 70℃; for 120h; Catalytic behavior; Time; Enzymatic reaction;	A n/a B 33.02%

...Expand

: oolongtheanin 3'-O-gallate

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: C36H24O16

C: C36H26O16

D: C43H32O21

Conditions

Conditions	Yield
With water at 60℃; for 4h;	A 24.7% B 3.3% C 5.6% D 5.6%

...Expand

: 99-50-3
3,4-Dihydroxybenzoic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With sodium dihydrogenphosphate at 25℃; for 0.25h; pH=7; Glovebox;	15%
Multi-step reaction with 2 steps 1: bromine 2: bei der Kalischmelze View Scheme

: 2922-42-1
(-)-3-dehydroshikimic acid

A: 99-50-3
3,4-Dihydroxybenzoic acid

B: 99-14-9
tricarallylic acid

C: 149-91-7
3,4,5-trihydroxybenzoic acid

D: 184105-29-1
dihydrogallic acid

E: 87-66-1
2-hydroxyresorcinol

Conditions

Conditions	Yield
With air; Na1.5H1.5PO4 at 40℃; for 50h; Rate constant; Mechanism; other oxidant, var. time;	A 12 % Spectr. B 14 % Spectr. C 13% D n/a E 3 % Spectr.

...Expand

: 56-23-5
tetrachloromethane

: 222320-76-5
3,4,5-tris[(methoxycarbonyl)oxy]benzoic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
at 20℃;

: 609-25-6
5-methylpyrogallol

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium hydroxide beim Schmelzen;

: 618-76-8
3,5-diiodo-4-hydroxybenzoic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium hydroxide beim Schmelzen;

: 16534-12-6
3,5-dihydroxy-4-bromobenzoic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium hydroxide beim Schmelzen;

: 61203-46-1
3-bromo-4,5-dihydroxybenzoic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium hydroxide beim Schmelzen;
bei der Kalischmelze;

: 3337-62-0
3,5-dibromo-4-hydroxybenzoic acid

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With barium dihydroxide; water at 175℃; im Kupferkessel;
With potassium hydroxide; copper(I) sulfate; water; copper(II) sulfate at 150℃;

: 529-44-2
myricetin

A: 108-73-6
3,5-dihydroxyphenol

B: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With potassium hydroxide at 130℃; for 1.5h;
durch Kalischmelze;

: 685876-41-9
4-galloyloxy-benzoic acid

: furan-2,3,5(4H)-trione pyridine (1:1)

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 99-96-7
4-hydroxy-benzoic acid

...Expand

: 84026-83-5
chebulic acid

: furan-2,3,5(4H)-trione pyridine (1:1)

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 186581-53-3, 908094-01-9
diazomethane

: sanguiin H-3

A: 492-62-6
alpha-D-glucopyranose

B: 149-91-7
3,4,5-trihydroxybenzoic acid

C: 2080-25-3
tetramethylellagic acid

D: 82203-12-1
sanguisorbic acid dilactone heptamethyl ether

Conditions

Conditions	Yield
With sulfuric acid 1.) reflux, 7.5 h, 2.) ether, overnight; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 96691-90-6
2,3-di-O-galloyl-D-4C1-glucopyranose

A: 50-99-7
D-glucose

B: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 3h;
With hydrogenchloride at 100℃; for 3h;

: 53209-27-1, 69624-79-9
quercetin-3-O-(2”-galloyl)-β-D-galactopyranoside

A: 482-36-0
Hyperoside

B: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With tannase In water at 37℃; for 2h;

: 67771-98-6
3,4,5-Trihydroxy-benzoic acid (2R,3S,4S,5R,6S)-6-(2,6-dihydroxy-4-hydroxymethyl-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-ylmethyl ester

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 64121-97-7
3,4,5-trihydroxybenzyl alcohol 4-O-β-D-glucopyranoside

Conditions

Conditions	Yield
With tannase for 0.5h; Ambient temperature; incubation;	A 29 mg B 61 mg

: 99786-30-8, 102489-93-0, 102489-94-1
2',5-di-O-galloyl-D-hamamelofuranose

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 469-33-0, 86420-47-5, 86420-48-6
2-hydroxymethyl-D-ribose

Conditions

Conditions	Yield
With tannase In water at 37℃; for 1.5h; hydrolysis of other O-galloyl-D-hamameloses;
With tannase In water at 37℃; for 1.5h;	A n/a B 70 mg

: 24093-81-0
methyl 3,5-dihydroxy-4-methoxybenzoate

: 149-91-7
3,4,5-trihydroxybenzoic acid

Conditions

Conditions	Yield
With hydrogen iodide; acetic anhydride at 145℃; for 0.5h;

: 95719-51-0
(-)-shikimic acid 3-O-gallate

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 138-59-0
shikimic acid

Conditions

Conditions	Yield
tannase In water at 37℃; for 3h; Product distribution;	A 40 mg B 43 mg

: 82958-44-9
11-O-(3',4',5'-trihydroxygalloyl)bergenin

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 477-90-7
bergenin

Conditions

Conditions	Yield
With trifluoroacetic acid In water for 30h; Heating;

: 82958-45-0
bergenin-4-O-gallate

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: 477-90-7
bergenin

Conditions

Conditions	Yield
With trifluoroacetic acid In water for 30h; Heating;

: euphorbin B-phenazine

A: 26922-99-6
1,3,4,6-tetra-O-galloyl-β-D-glucose

B: 149-91-7
3,4,5-trihydroxybenzoic acid

C: 3,4,6-tri-O-galloyl-α/β-D-glucose

D: 23094-69-1
corilagin

Conditions

Conditions	Yield
In water; acetone for 10h; Heating;	A 4 mg B 15 mg C 4 mg D 2 mg

...Expand

: carpinin B

A: 149-91-7
3,4,5-trihydroxybenzoic acid

B: carpinin D

Conditions

Conditions	Yield
enzymatic hydrolysis with tannase;

: 67-56-1
methanol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 99-24-1
methyl galloate

Conditions

Conditions	Yield
With sulfuric acid for 6h; Heating;	100%
With brominated modified sulfonic acid resin at 65℃; for 4h; Reagent/catalyst;	99%
With sulfuric acid for 1.5h; Heating / reflux;	97%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 18162-48-6
tert-butyldimethylsilyl chloride

: 185462-50-4
tert-butyldimethylsilyl 3,4,5-tri[(tert-butyldimethylsilyl)oxy]benzoate

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;	100%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; silylation;	98%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃;	91.9%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h; Substitution;

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 3,4,5-trihydroxybenzoic-2,6-d2 acid

Conditions

Conditions	Yield
With water-d2; hydrogen chloride for 6h; Inert atmosphere; Reflux;	99%
With Amberlyst 15; water-d2 at 90℃; for 24h; Substitution;
With nafion resin; water-d2 at 90℃; for 24h;

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 683-10-3
carboxymethyl-dodecyl-dimethyl-ammonium betaine

: dodecyldimethylglycine gallate

Conditions

Conditions	Yield
In methanol at 25℃; for 1h;	99%

: 71-23-8
propan-1-ol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 121-79-9
Propyl gallate

Conditions

Conditions	Yield
With brominated modified sulfonic acid resin at 100℃; for 5h;	98%
With toluene-4-sulfonic acid at 107℃; under 9308.91 Torr; for 0.133333h; Temperature; Wavelength; Sealed tube; Microwave irradiation;	94%
With cucurbit[6]uril-supported Keggin-type silicotungstic acid Q[6]-STA at 96.84℃; for 4h; Catalytic behavior; Time; Reagent/catalyst;	94.7%

: 64-17-5
ethanol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 831-61-8
Ethyl gallate

Conditions

Conditions	Yield
With brominated modified sulfonic acid resin at 80℃; for 5h; Reagent/catalyst;	98%
With toluene-4-sulfonic acid at 88℃; under 9308.91 Torr; for 0.133333h; Temperature; Wavelength; Time; Sealed tube; Microwave irradiation;	96%
With sulfuric acid at 70℃;	95%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 87-66-1
2-hydroxyresorcinol

Conditions

Conditions	Yield
With cucumber juice at 30 - 35℃; for 48h; Inert atmosphere; Green chemistry;	98%
With Citrobacter sp at 28℃; for 24h; enzymatic synthesis by bacterium in a mixed medium containing: 0.5percent maltose, 0.2percent (NH4)2HPO4, 0.1percent KH2PO4, 0.05percent KCl, 0.05percentMgSO4.7H2Oand 0.05percent yeast, pH=4.5;	97.4%
With Cocos nucifera juice at 20℃; for 48h; Inert atmosphere;	96%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 111-27-3
hexan-1-ol

: 1087-26-9
n-hexyl gallate

Conditions

Conditions	Yield
With sulfuric acid at 100℃; for 0.833333h; Microwave irradiation;	98%
With brominated hydrophobically modified sulfonic acid resin at 150℃; for 10h;	92%
Stage #1: 3,4,5-trihydroxybenzoic acid; hexan-1-ol With diisopropyl-carbodiimide In tetrahydrofuran at 0℃; for 0.5h; Stage #2: With dmap In tetrahydrofuran at 20℃; for 24h;	72%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: sodium gallate

Conditions

Conditions	Yield
With sodium carbonate In methanol at 20℃; Schlenk technique; Inert atmosphere;	98%
With sodium ethoxide In ethanol Inert atmosphere; Reflux;

: 149-91-7
3,4,5-trihydroxybenzoic acid

: gallic acid persulfate

Conditions

Conditions	Yield
With triethylamine sulfur trioxide; triethylamine In N,N-dimethyl-formamide at 86℃; for 1h; Microwave irradiation; Green chemistry;	98%

: 112-92-5
1-octadecanol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 10361-12-3
octadecyl 3,4,5-trihydroxybenzoate

Conditions

Conditions	Yield
With cation exchange resin 731 In ethyl acetate at 80 - 85℃; Dean-Stark;	97.2%
With toluene-4-sulfonic acid In 1,4-dioxane at 160℃;	73%
With dicyclohexyl-carbodiimide In tetrahydrofuran at 0℃; for 10h;	61%
With naphthalene-2-sulfonate; methoxybenzene; nitrobenzene unter Entfernen des entstehenden Wassers;
With toluene-4-sulfonic acid In toluene at 125℃; for 4h; Temperature;

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 71-36-3
butan-1-ol

: 1083-41-6
n-butyl gallate

Conditions

Conditions	Yield
With sulfuric acid at 100℃; for 0.833333h; Microwave irradiation;	97%
With brominated modified sulfonic acid resin at 120℃; for 5h;	96%
With toluene-4-sulfonic acid at 128℃; under 9308.91 Torr; for 0.15h; Temperature; Wavelength; Sealed tube; Microwave irradiation;	93%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 6681-13-6
Hernandezine

: C39H44N2O7*2C7H6O5

Conditions

Conditions	Yield
In ethanol at 20℃; for 0.5h;	97%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 149-73-5
trimethyl orthoformate

: C9H8O6

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene at 105℃; Inert atmosphere;	97%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 122-51-0
orthoformic acid triethyl ester

: C10H10O6

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene at 103℃; for 8h; Temperature; Inert atmosphere;	97%

: 111-87-5
octanol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 1034-01-1
Octyl gallate

Conditions

Conditions	Yield
With sulfuric acid at 100℃; for 0.833333h; Microwave irradiation;	96%
With dicyclohexyl-carbodiimide In tetrahydrofuran for 20h;	89%
With dicyclohexyl-carbodiimide In tetrahydrofuran for 20h;	89%

: 68252-28-8, 68567-97-5, 88929-35-5, 62613-82-5
oxiracetam

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 1392812-94-0
C6H10N2O3*C7H6O5

Conditions

Conditions	Yield
In methanol for 24h;	96%

: 75-44-5
phosgene

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 408340-58-9
7-hydroxy-2-oxo-benzo[1,3]dioxole-5-carboxylic acid

Conditions

Conditions	Yield
With sodium carbonate; triethylamine In dichloromethane; water at 12℃; for 1h; Temperature;	96%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 616-38-6
carbonic acid dimethyl ester

: 118-41-2
Eudesmic acid

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 120℃; Concentration; Inert atmosphere;	95.6%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 82-12-2
rufigallol

Conditions

Conditions	Yield
With sulfuric acid at 80 - 120℃; for 5h; Autoclave;	95%
With sulfuric acid at 100℃; Inert atmosphere;	92.2%
With sulfuric acid for 0.025h; microwave irradiation;	80%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 108-24-7
acetic anhydride

: 6635-24-1
3,4,5-triacetoxybenzoic acid

Conditions

Conditions	Yield
at 130℃; for 4h;	95%
for 3h; Reflux;	95%
With sulfuric acid at 21 - 75℃;	93%

: 492-98-8
2,2'-biimidazole

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 7732-18-5
water

: 6018-89-9
nickel(II) acetate tetrahydrate

: [Ni(2,2'-biimidazole)2(OH2)2](3,4,5-tris-hydroxy-benzoate)2*4H2O

Conditions

Conditions	Yield
In water 2,2'-biimidazole added to a soln. of metal acetate in hot water, a soln.of 3,4,5-tris-hydroxy-benzoic acid in hot water added; concn., controlled evapn. at room temp. for 2-3 wk; elem. anal.;	95%

...Expand

: 78-83-1
2-methyl-propan-1-ol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 3856-05-1
isobutyl 3,4,5-trihydroxybenzoate

Conditions

Conditions	Yield
With brominated hydrophobically modified sulfonic acid resin at 110℃; for 8h;	94%
With toluene-4-sulfonic acid at 118℃; under 9308.91 Torr; for 0.15h; Temperature; Wavelength; Sealed tube; Microwave irradiation;	92%
With dicyclohexyl-carbodiimide In tetrahydrofuran at 0℃; for 10h;	87%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 67-63-0
isopropyl alcohol

: 1138-60-9
isopropyl 3,4,5-trihydroxybenzoate

Conditions

Conditions	Yield
With brominated modified sulfonic acid resin at 85℃; for 7h;	94%
With sulfuric acid at 120℃; for 2h;	94%
With toluene-4-sulfonic acid at 92℃; under 9308.91 Torr; for 0.133333h; Temperature; Wavelength; Sealed tube; Microwave irradiation;	93%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 39809-25-1
Penciclovir

: C10H15N5O3*C7H6O5*H2O

Conditions

Conditions	Yield
With water In ethanol at 20℃; for 24h;	94%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 107-43-7
betaine

: betaine gallate

Conditions

Conditions	Yield
In methanol at 60℃; for 12h; Inert atmosphere;	93.32%

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 108-24-7
acetic anhydride

: 855291-88-2
triacetylgallic acid

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 2.5h; Cooling with ice;	92.6%

: 71-41-0
pentan-1-ol

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 4568-93-8
pentyl 3,4,5-trihydroxybenzoate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 148℃; under 9308.91 Torr; for 0.166667h; Temperature; Wavelength; Sealed tube; Microwave irradiation;	92%
With brominated modified sulfonic acid resin at 135℃; for 8h;	92%
With sulfuric acid at 100℃; for 0.833333h; Microwave irradiation;	83%

: vanadocene

: 149-91-7
3,4,5-trihydroxybenzoic acid

: cyclopentadienylvanadium digallate

Conditions

Conditions	Yield
In diethyl ether byproducts: C5H6, H2; (vac. or Ar); addn. of acid to V-complex in ether (20°C, 48 h); filtration, washing (ether), drying; elem. anal.;	92%

Gallic acid Chemical Properties

Molecular Structure of Gallic acid (CAS NO.149-91-7):

IUPAC Name: 3,4,5-trihydroxybenzoic acid
Empirical Formula: C₇H₆O₅
Molecular Weight: 170.1195
H bond acceptors: 5
H bond donors: 4
Freely Rotating Bonds: 4
Polar Surface Area: 53.99 ?2
Index of Refraction: 1.73
Molar Refractivity: 38.82 cm³
Molar Volume: 97.2 cm³
Surface Tension: 109.2 dyne/cm
Density: 1.749 g/cm³
Flash Point: 271 °C
Enthalpy of Vaporization: 81.07 kJ/mol
Boiling Point: 501.1 °C at 760 mmHg
Vapour Pressure: 7.32E-11 mmHg at 25°C
EINECS: 205-749-9
Melting point: 252 °C (dec.)(lit.)
Water Solubility: 12 g/L cold water
Merck: 14,4345
BRN: 2050274
Stability: Stability Stable, but may discolour upon exposure to light. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, acid chlorides, acid anhydrides.
Product Categories: Pharmaceutical Intermediates; Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
InChI
InChI=1/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
Smiles
c1(cc(c(O)c(c1)O)O)C(O)=O

Gallic acid Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	4300mg/kg (4300mg/kg)		Pharmacology and Toxicology Vol. 64, Pg. 247, 1989.
mouse	LD50	intravenous	320mg/kg (320mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02597,
rabbit	LD50	oral	5gm/kg (5000mg/kg)	LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: OTHER CHANGES LIVER: OTHER CHANGES	American Journal of Veterinary Research. Vol. 23, Pg. 1264, 1962.
rat	LDLo	subcutaneous	5gm/kg (5000mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 497, 1969.

Gallic acid Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Gallic acid Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-24/25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 2
RTECS: LW7525000
F: 8-9-23

Gallic acid Specification

Gallic acid , with CAS number of 149-91-7, can be called 3,4,5-Trihydroxybenzoesäure ; 3,4,5-trihydroxy-Benzoic acid ; Acid, Gallic ; Acide 3,4,5-trihydroxybenzoïque ; benzoic acid, 3,4,5-trihydroxy- . It is a white powder, Gallic acid do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids. These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.

Product Name

Gallic acid

Synthetic route

Gallic acid Chemical Properties

Gallic acid Toxicity Data With Reference

Gallic acid Consensus Reports

Gallic acid Safety Profile

Gallic acid Specification

Related Products

Hot Products