Product Name

  • Name

    1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

  • EINECS 664-293-2
  • CAS No. 112811-59-3
  • Article Data16
  • CAS DataBase
  • Density 1.386 g/cm3
  • Solubility
  • Melting Point 162 °C
  • Formula C19H22FN3O4
  • Boiling Point 607.8 °C at 760 mmHg
  • Molecular Weight 375.4
  • Flash Point 321.4 °C
  • Transport Information
  • Appearance white powder
  • Safety 36/37
  • Risk Codes 20/21/22
  • Molecular Structure Molecular Structure of 112811-59-3 (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid)
  • Hazard Symbols Xn
  • Synonyms 1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicacid;G-Cebran;Gaity;Gatiflo;Gatilox;Gatiquin;Gatispan;Tequin;Tymer;Zymar;
  • PSA 83.80000
  • LogP 2.37420

Gatifloxacin Chemical Properties

Molecular Structure of Andrographis (CAS NO.112811-59-3):

IUPAC Name: 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid 
Empirical Formula: C19H22FN3O4
Molecular Weight: 375.394
H bond acceptors: 7
H bond donors: 2
Freely Rotating Bonds: 4
Polar Surface Area: 62.32 Å2
Index of Refraction: 1.616
Molar Refractivity: 94.64 cm3
Molar Volume: 270.7 cm3
Surface Tension: 57.7 dyne/cm
Density: 1.386 g/cm3
Flash Point: 321.4 °C
Enthalpy of Vaporization: 94.96 kJ/mol
Boiling Point: 607.8 °C at 760 mmHg
Vapour Pressure: 1.26E-15 mmHg at 25°C
Melting point: 162°C
Storage temp: Store at 0-5°C
InChI
InChI=1/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
Smiles
n1(c2c(cc(c(c2OC)N2C[C@@H](C)NCC2)F)c(c(c1)C(=O)O)=O)C1CC1
Product Categories: API; Intermediates & Fine Chemicals; Pharmaceuticals; API's

Gatifloxacin History

Bristol-Myers Squibb introduced Gatifloxacin in 1999 under the proprietary name Tequin for the treatment of respiratory tract infections, having licensed the medication from Kyorin Pharmaceutical Company of Japan. Allergan produces an eye-drop formulation called Zymar.

Gatifloxacin Specification

  Andrographis , with CAS number of 112811-59-3, can be called 1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicacid ; G-Cebran ; Gaity ; Gatiquin . It is a white to light yellow powder, used to inhibit the bacterial enzymes DNA gyrase and topoisomerase IV.

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