Glyoxylic acid supplier | CasNO.298-12-4

Name
Glyoxylic acid
EINECS 206-058-5
CAS No. 298-12-4
Article Data400
CAS DataBase
Density 1.384 g/cm³
Solubility miscible with water
Melting Point -93 °C
Formula C₂H₂O₃
Boiling Point 224.601 °C at 760 mmHg
Molecular Weight 74.0361
Flash Point 103.914 °C
Transport Information UN 3265 8/PG 2
Appearance clear yellow solution
Safety 26-36/37/39-45-37/39-24
Risk Codes 34-43-41
Molecular Structure
Hazard Symbols Xi,C
Synonyms Acetic acid, oxo- (9CI);Glyoxylic acid (8CI);2-oxoacetate;glyoxalate;Glyoxylic;Oxalaldehydic acid;Oxoacetic acid;Acetic acid, oxo-, sodium salt;glyoxylate;alpha-Ketoacetic acid;Formic acid, formyl-;Acetic acid, oxo;Oxoethanoic acid;
PSA 54.37000
LogP -0.73010

Synthetic route

: 35065-59-9
N-chloroglycine

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With sodium hydroxide; sodium perchlorate In water at 298℃; Decomposition of (N-Cl)- , (N-Br)-α-amino acids, dipeptides, amines in near neutral or mild basic conditions;	100%
With sodium hydroxide at 24.9℃; Rate constant; Kinetics; Thermodynamic data; other N-chloro- and N-bromo-α-amino acids; var. temp., NaOH conc. and ionic strength of solution; ΔS(excit.), ΔH(excit.); mechanism;
With hydroxide In water at 24.9℃; Product distribution;

: 563-96-2
2,2-dihydroxyacetic acid

A: 144-62-7
oxalic acid

B: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With oxygen; ethylenediamine; Flavin mononucleotide In water at 15℃; under 4350.3 Torr; for 77h; glycolate oxidase, Aspergillus niger catalase, pH 8-9;	A 0.2% B 99.8%

: 79-14-1
glycolic Acid

A: 144-62-7
oxalic acid

B: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With diazoacetic acid ethyl ester; oxygen; Flavin mononucleotide In water at 5℃; under 6205.8 Torr; for 1h; Pichia Pastoris transformant MSO10 (423 IU of glycolate oxidase and 869000 IU of catalase), pH 9.25;	A 1.3% B 98.7%
With oxygen; 3,3-dimethyldioxirane In acetone at 32℃; Kinetics; Further Variations:; Temperatures; Oxidation;

: 108-31-6
maleic anhydride

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
Stage #1: maleic anhydride With water In methanol; ethyl acetate at 65℃; for 0.833333h; Stage #2: With ozone In methanol; ethyl acetate at 5℃; for 3h; Solvent; Temperature; Time;	98.3%

: 79-14-1
glycolic Acid

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With acetic acid; bis(2-ethyl-1H-benzimidazolinium) dichromate at 20℃; for 0.5h;	89%
With acetic acid; bis(2-methyl-1H-benzimidazolinium) dichromate In ethanol at 20℃; for 0.5h;	89%
With glycolate oxidase; oxygen; Flavin mononucleotide In various solvent(s) at 30℃; for 24h; Oxidation;	80%

: 131543-46-9
Glyoxal

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
Stage #1: Glyoxal With ammonium hydroxide; dihydrogen peroxide; iron(II) sulfate at 7 - 8℃; Stage #2: With sulfuric acid In ethanol at 140℃; for 3h; Stage #3: In water at 95 - 98℃; for 2h; Temperature;	88%
Stage #1: Glyoxal With hydrogenchloride; nitric acid In water at 45℃; Stage #2: With oxygen; sodium nitrite In water at 43 - 60℃; under 3000.3 Torr; for 4h; Product distribution / selectivity;	78%
With Tri-n-octylamine In octane at 45℃; under 1125.11 Torr; for 4h;	57.52%

: 621-84-1
O-benzyl carbamate

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
	83%

: 79866-88-9
2-chloro-2,3-dimethoxy-1,4-dioxane

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With methanol; water at 20 - 25℃; for 1h;	81%

: 140-10-3
(E)-3-phenylacrylic acid

A: 100-52-7
benzaldehyde

B: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With potassium hexacyanoferrate(III) In perchloric acid; acetic acid at 50℃; Mechanism; Kinetics; Ea, ΔH(excit.), ΔS(excit.), other temperatures, other concentrations acids;	A 80% B 10%
With potassium bromate; thallium(III) sulfate; sulfuric acid In water; acetic acid at 40℃; for 60h; Rate constant; Mechanism; Thermodynamic data; other mineral acid; other metal ion; E(excit.), ΔH(excit.), ΔS(excit.), ΔG(excit.);	A 75% B 25%
With sulfuric acid; mercury(II) diacetate; bromate In water; acetic acid Mechanism; Kinetics; Thermodynamic data; effect of solvent polarity, temperature, mercury acetate on oxidation ΔH(excit.), ΔS(excit.), ΔG(excit.);

: 107-97-1
sarcosine

A: 298-12-4
Glyoxilic acid

B: C3H5BrNO2(1-)

Conditions

Conditions	Yield
With hypobromite In sodium hydroxide at 35℃; Kinetics; Mechanism;	A 80% B n/a

: 56-40-6
glycine

A: 298-12-4
Glyoxilic acid

B: C2H3BrNO2(1-)

Conditions

Conditions	Yield
With hypobromite In sodium hydroxide at 35℃; Kinetics; Mechanism;	A 80% B n/a

: C2H3BrNO2(1-)

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With hypobromite In sodium hydroxide at 35℃; Kinetics; Mechanism;	80%

: C3H5BrNO2(1-)

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With hypobromite In sodium hydroxide at 35℃; Kinetics; Mechanism;	80%

: 107-93-7
(E)-but-2-enoic acid

A: 75-07-0
acetaldehyde

B: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With potassium hexacyanoferrate(III) In perchloric acid; acetic acid at 50℃; Mechanism; Kinetics; Ea, ΔH(excit.), ΔS(excit.), other temperatures, other concentrations acids;	A 75% B 10%
With potassium bromate; thallium(III) sulfate; sulfuric acid In water; acetic acid at 40℃; for 60h; Rate constant; Mechanism; Thermodynamic data; other mineral acid; other metal ion; E(excit.), ΔH(excit.), ΔS(excit.), ΔG(excit.);	A 62% B n/a
With N-chloro-succinimide; perchloric acid; palladium dichloride at 35℃; Kinetics; Further Variations:; concentration;

: 79-14-1
glycolic Acid

A: 64-18-6
formic acid

B: 144-62-7
oxalic acid

C: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With oxygen In water at 5℃; under 6205.8 Torr; for 23h; Product distribution; Escherichia coli transformant WT-GAO, pH 9.2; other metabolically inactive microbial transformant;	A 5.6% B 1.1% C 74.4%

...Expand

: 110-16-7
maleic acid

A: 7722-84-1
dihydrogen peroxide

B: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With oxygen; ozone In methanol; water at -15℃;	A 68% B n/a
With oxygen; ozone; corundum#dotCo In methanol; water at -15℃;	A 56% B n/a
With oxygen; ozone; Co-Kat In methanol; water at -15℃;	A 25% B n/a

: 124-38-9
carbon dioxide

A: 64-18-6
formic acid

B: 144-62-7
oxalic acid

C: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With tetramethyl ammoniumhydroxide; tetramethlyammonium chloride In water for 4.25h; pH=9, electrolysis -1.88 V , 3.0 mA, graphite electrode;	A 65% B 6% C 28%
With tetraethylammonium perchlorate In water electrodeduction, cathode: Pb vs. Ag/AgCl; Yield given;

...Expand

: 56-40-6
glycine

A: 50-00-0
formaldehyd

B: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With bromine; perchlorate(1-) at 35℃; Kinetics; Mechanism; Rate constant; other α-amino acids; k2 = 50.0 x 10-7 s-1;	A 50% B 45%
With nickel(II) sulphate; hydroxide; Nitrogen dioxide In water Product distribution; Irradiation; further reagnt ratio, at pH 7.3;	A 0.2% B 2.2%

: 79-14-1
glycolic Acid

A: 50-00-0
formaldehyd

B: 64-18-6
formic acid

C: 124-38-9
carbon dioxide

D: 201230-82-2
carbon monoxide

E: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With iron(III) phosphate; oxygen at 240 - 270℃; for 0.000694444h; Product distribution; other catalysts;	A 3.9% B 0.7% C n/a D n/a E 39.6%

...Expand

: 107-21-1
ethylene glycol

A: 50-00-0
formaldehyd

B: 131543-46-9
Glyoxal

C: 75-07-0
acetaldehyde

D: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With nitrogen; oxygen; iron(III) phosphate doped with Mo(VI) In water at 310℃; Further byproducts given;	A 33.2% B 26.5% C 11.7% D 2.4%
With nitrogen; oxygen; iron(III) phosphate doped with Mo(VI) In water at 300℃; Further byproducts given;	A 20.6% B 19.8% C 16.6% D 3.3%

...Expand

: 117659-76-4
ethylenediamine tetraacetic acid

A: 50-00-0
formaldehyd

B: 298-12-4
Glyoxilic acid

C: 142-73-4
iminodiacetic acid

Conditions

Conditions	Yield
With ozone In water Kinetics; Oxidation;	A 15% B 32% C 20%

...Expand

: 470-23-5
D-fructose

A: 64-18-6
formic acid

B: 79-14-1
glycolic Acid

C: 64-19-7
acetic acid

D: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With aluminium(III) triflate; dihydrogen peroxide In acetonitrile at 70℃; for 12h;	A 17.6% B 14.5% C 8.7% D 5.4%

...Expand

: 60-80-0
antipyrine

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
In water at 20℃; for 5h; Irradiation;	13%

: 91-20-3
naphthalene

A: 497-16-5
oxomalonaldehyde

B: 7722-84-1
dihydrogen peroxide

C: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With oxygen; ozone; Mn-Katalysator In acetic acid at 16℃;	A n/a B 0.1% C n/a

...Expand

: 495-69-2
Hippuric Acid

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; iron(II) sulfate

: 623-73-4
diazoacetic acid ethyl ester

: 64-17-5
ethanol

: 1972-28-7
diethylazodicarboxylate

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
bei Abwesenheit eines Verduennungsmittels gibt ein Produkt, und Kochen dieses mit verd.Salzsaeure;

...Expand

: 623-73-4
diazoacetic acid ethyl ester

: 1972-28-7
diethylazodicarboxylate

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
Kochen mit verd. Salzsaeure;

: 79-43-6
dichloro-acetic acid

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With water; sodium carbonate at 140 - 150℃;
With sodium hydroxide; water at 140 - 150℃;

: 60-27-5
creatinine

: 298-12-4
Glyoxilic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; iron(II) sulfate

: 60-35-5
acetamide

: 298-12-4
Glyoxilic acid

: 63327-49-1
N-acetyl-α-hydroxyglycine

Conditions

Conditions	Yield
In water; acetone for 18h; Heating / reflux;	100%
In water
In acetone for 18h; Reflux;

: 100-63-0
phenylhydrazine

: 298-12-4
Glyoxilic acid

: 6000-60-8
phenylhydrazonoacetic acid

Conditions

Conditions	Yield
With hydrogenchloride In water	100%
In water at 20℃; for 1h;	95%
With hydrogenchloride In water at 0 - 20℃; for 1h;	94%

: 57-04-5
dihydroxyacetone phosphate

: 298-12-4
Glyoxilic acid

: C5H7O8P(2-)

Conditions

Conditions	Yield
aldolase In water	100%

: 4248-19-5
tert-butyl carbamate

: 298-12-4
Glyoxilic acid

: 96625-24-0
Nα-(tert-butoxycarbonyl)-α-hydroxyglycine

Conditions

Conditions	Yield
In acetone for 4h; Heating;	100%
In diethyl ether for 72h; Ambient temperature;	2.5 g
In diethyl ether for 72h; Ambient temperature;
In acetone for 5h; Heating;
In acetone Heating;

: 13782-38-2
2,4-dimethylcarbonohydrazide

: 298-12-4
Glyoxilic acid

: 87773-89-5
Hexahydro-1,5-dimethyl-6-oxo-1,2,4,5-tetrazin-3-carbonsaeure

Conditions

Conditions	Yield
In methanol	100%
In water at 20℃; for 0.5h;	96%
In diethyl ether; water for 1h;	69%

: 2687-43-6
O-benzylhydoxylamine hydrochloride

: 298-12-4
Glyoxilic acid

: 77845-97-7
2-[(phenylmethoxy)imino]-acetic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In water at 20℃; for 2h; Inert atmosphere;	100%
With water In acetonitrile for 12h; Ambient temperature;	97%
With sodium acetate In methanol; water Ambient temperature;	94%

: 84418-43-9
9-fluorenylmethyl carbamate

: 298-12-4
Glyoxilic acid

: 176638-02-1
9-fluorenylmethoxycarbonyl-α-hydroxyglycine

Conditions

Conditions	Yield
In acetone for 5h; Heating;	100%
In ethyl acetate for 6h; Heating;	73%

: 55-21-0
benzamide

: 298-12-4
Glyoxilic acid

: 19791-95-8, 19791-97-0, 16555-77-4
α-hydroxyhippuric acid

Conditions

Conditions	Yield
In water; acetone for 19h; Heating / reflux;	100%
In acetone Heating;
In acetone for 19h; Reflux;

: 96-76-4
2,4-di-tert-Butylphenol

: 298-12-4
Glyoxilic acid

: 163489-63-2
5,7-di-tert-butyl-3-hydroxy-3H-benzofuran-2-one

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In water; 1,2-dichloro-ethane for 3.5h; Heating;	100%
toluene-4-sulfonic acid In water; 1,2-dichloro-ethane for 3.5h; Heating / reflux;	100%
With toluene-4-sulfonic acid In toluene for 3h; Heating / reflux;

: 35406-29-2
2,4-dicyclohexylphenol

: 298-12-4
Glyoxilic acid

: 5,7-dicyclohexyl-3-hydroxy-3H-benzofuran-2-one

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In water; 1,2-dichloro-ethane Heating;	100%

: 6294-89-9
hydrazinecarboxylic acid methyl ester

: 298-12-4
Glyoxilic acid

: 332868-35-6
[(methoxycarbonyl)hydrazono]acetic acid

Conditions

Conditions	Yield
In water for 7h;	100%

: 2114-11-6
allyl carbamate

: 298-12-4
Glyoxilic acid

: 92138-25-5
(RS)-N-<(allyloxy)carbonyl>-α-hydroxyglycine

Conditions

Conditions	Yield
In acetone for 5h; Heating;	100%

: 2-(6-fluoro-1H-indol-3-yl)ethan-1 -amine hydrochloride

: 298-12-4
Glyoxilic acid

: 783349-33-7
7-fluoro-2,3,4,9-tetrahydro-1H-β-carboline-1-carboxylic acid

Conditions

Conditions	Yield
In water; ethyl acetate at 20℃; for 16h; pH=4.4; Aqueous acetate buffer;	100%
With acetate buffer In ethyl acetate at 20℃; for 16h; pH=4.4;	100%

: 271-89-6
1-benzofurane

: 626-43-7
3,5-Dichloroaniline

: 298-12-4
Glyoxilic acid

: 1,3-dichloro-5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid

Conditions

Conditions	Yield
indium(III) triflate In acetonitrile at 50℃; for 0.191667h; Product distribution / selectivity; Microwave irradiation;	100%
montmorillonit KSF In acetonitrile at 50℃; for 0.191667h; Product distribution / selectivity; Microwave irradiation;	79%
ytterbium(III) triflate In acetonitrile at 50℃; for 0.191667h; Product distribution / selectivity; Microwave irradiation;	77%

...Expand

: 100124-06-9
4-dibenzofurylboronic acid

: 626-43-7
3,5-Dichloroaniline

: 298-12-4
Glyoxilic acid

: 745013-41-6
(dibenzofuran-4-yl)-(3,5-dichlorophenylamino)acetic acid

Conditions

Conditions	Yield
In dichloromethane at 20℃;	100%

...Expand

: 1023795-48-3
4-hydrazinyl-2-methoxybenzonitrile

: 298-12-4
Glyoxilic acid

: 2-(2-(4-cyano-3-methoxyphenyl)hydrazono)acetic acid

Conditions

Conditions	Yield
In water for 16h;	100%

: 110-89-4
piperidine

: 16419-60-6
2-Methylphenylboronic acid

: 298-12-4
Glyoxilic acid

: 1017212-36-0
2-(piperidin-1-yl)-2-o-tolylacetic acid

Conditions

Conditions	Yield
In dichloromethane at 20℃;	100%

...Expand

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 298-12-4
Glyoxilic acid

: 163105-89-3
2-methoxy-pyridine-5-boronic acid

: 1352451-01-4
2-(2-(methoxycarbonyl)thiophen-3-ylamino)-2-(6-methoxypyridin-3-yl)acetic acid

Conditions

Conditions	Yield
In acetonitrile for 2h; Reflux;	100%
In acetonitrile for 2h; Reflux;	100%

...Expand

: 160005-43-6
2-(4-bromothiophen-2-yl)acetonitrile

: 298-12-4
Glyoxilic acid

: 917772-57-7
C8H4BrNO2S

Conditions

Conditions	Yield
With potassium carbonate In methanol; water at 20℃; for 4h;	100%

: 110-89-4
piperidine

: 6165-68-0
thiophene boronic acid

: 298-12-4
Glyoxilic acid

: 2-(piperidin-1-yl)-2-(thiophen-2-yl)acetic acid

Conditions

Conditions	Yield
In acetonitrile for 2.5h; Reflux;	100%

...Expand

: 110-89-4
piperidine

: 6165-69-1
Thien-3-ylboronic acid

: 298-12-4
Glyoxilic acid

: 1218394-64-9
2-(piperidin-1-yl)-2-(thiophen-3-yl)acetic acid

Conditions

Conditions	Yield
In acetonitrile for 5h; Reflux;	100%

...Expand

: 5-amino-2-cyclopropylmethylisoquinolinium bromide

: 298-12-4
Glyoxilic acid

: (2-cyclopropylmethyl-1,2,3,4-tetrahydroisoquinolin-5-ylamino)acetic acid

Conditions

Conditions	Yield
With 10 wt% Pd(OH)2 on carbon; hydrogen In methanol at 20℃; under 7500.75 Torr; Autoclave;	100%

: 1001183-88-5
2-cyclopropylmethyl-1,2,3,4-tetrahydroisoquinolin-5-ylamine

: 298-12-4
Glyoxilic acid

: (2-cyclopropylmethyl-1,2,3,4-tetrahydroisoquinolin-5-ylamino)acetic acid

Conditions

Conditions	Yield
With sodium cyanoborohydride; triethylamine In methanol at 0 - 20℃; for 4.5h;	100%

: (S)-(+)-(1,2,3,4-tetrahydronaphth-1-ylamino)acetaldehyde dimethyl acetal

: 122775-35-3
3,4-Dimethoxyphenylboronic acid

: 298-12-4
Glyoxilic acid

: N-2,2-dimethoxyethyl-N-[1-(1,2,3,4-tetrahydro)naphth-1-yl]-2-(3,4-dimethoxyphenyl)glycine

Conditions

Conditions	Yield
Stage #1: 3,4-Dimethoxyphenylboronic acid; Glyoxilic acid In dichloromethane at 20℃; Petasis Reaction; Stage #2: (S)-(+)-(1,2,3,4-tetrahydronaphth-1-ylamino)acetaldehyde dimethyl acetal In dichloromethane at 20℃; for 72h; Petasis Reaction; diastereoselective reaction;	100%

...Expand

: (R)-(-)-(1-indanamino)acetaldehyde dimethyl acetal

: 122775-35-3
3,4-Dimethoxyphenylboronic acid

: 298-12-4
Glyoxilic acid

: N-2,2-dimethoxyethyl-N-[1-(1,2,3,4-tetrahydro)naphth-1-yl]-2-(3,4-dimethoxyphenyl)glycine

Conditions

Conditions	Yield
Stage #1: 3,4-Dimethoxyphenylboronic acid; Glyoxilic acid In dichloromethane at 20℃; Petasis Reaction; Stage #2: (R)-(-)-(1-indanamino)acetaldehyde dimethyl acetal In dichloromethane at 20℃; for 72h; Petasis Reaction; diastereoselective reaction;	100%

...Expand

: 68176-57-8
4-(tert-butyl)-1,2-diaminobenzene

: 298-12-4
Glyoxilic acid

: C12H16N2O

Conditions

Conditions	Yield
Stage #1: 4-(tert-butyl)-1,2-diaminobenzene; Glyoxilic acid With hydrogenchloride In water for 3h; Reflux; Inert atmosphere; Stage #2: With sodium hydroxide at 0℃; pH=Ca. 8; Inert atmosphere;	100%

: (+/-) (R,R/S,S) 2,2'-((ethane-1,2-diylbis(azanediyl))bis(pyridin-2-ylmethylene))diphenol

: 298-12-4
Glyoxilic acid

: Janus chelate

Conditions

Conditions	Yield
With sodium cyanoborohydride; sodium hydrogencarbonate In methanol at 20℃; for 24h;	100%
With sodium cyanoborohydride; sodium hydrogencarbonate In methanol at 20℃; for 24h;	100%

: 56893-13-1
(2-oxo-2-(4-(trifluoromethyl)phenyl)ethyl)triphenylphosphonium bromide

: 298-12-4
Glyoxilic acid

: 85293-41-0
4-(4-trifluoromethylphenyl)-4-oxo-2-butenoic acid

Conditions

Conditions	Yield
With triethylamine In methanol; chloroform at 25℃; for 15h; Wittig Olefination;	100%

: 96-31-1
N,N'-Dimethylurea

: 298-12-4
Glyoxilic acid

: 64732-10-1
5-hydroxy-1,3-dimethylimidazolidine-2,4-dione

Conditions

Conditions	Yield
In ethyl acetate Solvent;	100%

Glyoxylic acid Chemical Properties

The Molecular Structure of Glyoxylic acid (CAS NO.298-12-4):

Empirical Formula: C₂H₂O₃
Molecular Weight: 74.0355
IUPAC Name: oxaldehydic acid
Appearance: clear yellow solution
Nominal Mass: 74 Da
Average Mass: 74.0355 Da
Monoisotopic Mass: 74.000394 Da
Index of Refraction: 1.403
Molar Refractivity: 13.06 cm³
Molar Volume: 53.4 cm³
Surface Tension: 50.2 dyne/cm
Density: 1.384 g/cm³
Flash Point: 103.9 °C
Enthalpy of Vaporization: 50.8 kJ/mol
Boiling Point: 224.6 °C at 760 mmHg
Vapour Pressure: 0.0331 mmHg at 25°C
Storage temp: 2-8°C
Water Solubility: miscible
InChI
InChI=1/C2H2O3/c3-1-2(4)5/h1H,(H,4,5)
Smiles
C(C=O)(O)=O
Product Categories: Pharmaceutical Intermediates
Synonyms: Formylformic Acid ; Oxoethanoic acid ; Oxoacetic acid ; Formylformic acid ; Alpha-Ketoacetic Acid ; Oxalaldehydic Acid
The conjugate base of Glyoxylic acid (CAS NO.298-12-4) is known as glyoxylate. It is an intermediate of the glyoxylate cycle, enables organisms, such as fungi, bacteria, and plants to convert fatty acids into carbohydrates .

Glyoxylic acid Uses

Glyoxylic acid (CAS NO.298-12-4) is used as intermediates of spice, medicine, dyes, plastics and varnish materials,and it also used in pharmacy.

Glyoxylic acid Toxicity Data With Reference

1.		mmo-sat 200 µg/plate ABCHA6 47,2461,83
2.		ims-rat LDLo:25 mg/kg		BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale. 36 (1960),1937.

Glyoxylic acid Consensus Reports

Reported in EPA TSCA Inventory

Glyoxylic acid Safety Profile

Hazard Codes: Corrosive C Irritant Xi
Risk Statements: 34-43-41
R34: Causes burns
R43: May cause sensitization by skin contact
R41: Risk of serious damage to the eyes
Safety Statements: 26-36/37/39-45-37/39-24
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39: Wear suitable gloves and eye/face protection
S24: Avoid contact with skin
RIDADR: UN 3265 8/PG 2
WGK Germany: 1
RTECS: MD4550000
HazardClass: 8
PackingGroup: III
Poison by intramuscular route. Mutation data reported. A skin, eye, and mucous membrane irritant. When heated to decomposition it emits acrid smoke and fumes.

Product Name

Glyoxylic acid

Synthetic route

Glyoxylic acid Chemical Properties

Glyoxylic acid Uses

Glyoxylic acid Toxicity Data With Reference

Glyoxylic acid Consensus Reports

Glyoxylic acid Safety Profile

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