Isopropanol supplier | CasNO.67-63-0

Name
Isopropanol
EINECS 200-661-7
CAS No. 67-63-0
Article Data879
CAS DataBase
Density 0.791 g/cm³
Solubility miscible with water, ethanol, ether and chloroform
Melting Point -89.5 °C
Formula C₃H₈O
Boiling Point 72.993 °C at 760 mmHg
Molecular Weight 60.0959
Flash Point 11.667 °C
Transport Information UN 1219 3/PG 2
Appearance colourless liquid
Safety 7-16-24/25-26-36/37
Risk Codes 11-36-67-40-10-36/38
Molecular Structure
Hazard Symbols Xi,F,Xn
Synonyms Isopropylalcohol (8CI);1-Methylethanol;1-Methylethyl alcohol;2-Hydroxypropane;2-Propyl alcohol;Alcojel;Alcosolve2;Autosept;Avantin;Avantine;Combi-Schutz;Dimethylcarbinol;Hartosol;IPS 1;IPS 1 (alcohol);Imsol A;Isohol;Isopropyl alcohol;
PSA 20.23000
LogP 0.38710

Synthetic route

: 67-64-1
acetone

: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With hydrogen; mer-Os(PPh3)3HBr(CO) In toluene at 150℃; under 51680 Torr; for 3h;	100%
With hydrogen; sodium methylate; chromium(0) hexacarbonyl In methanol at 120℃; under 75006 Torr; for 3h;	100%
With hydrogen; Ru((R,R)-cyP2N2)HCl In benzene-d6 at 20℃; under 2280.15 Torr; for 12h; Product distribution / selectivity; Alkaline conditions; Cooling with liquid nitrogen;	100%

: 67-56-1
methanol

: 108-21-4
Isopropyl acetate

A: 79-20-9
acetic acid methyl ester

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With triethylamine at 20℃; under 8250660 Torr; for 2h; Product distribution;	A 100% B n/a

...Expand

: 67-56-1
methanol

: 939-48-0
isopropyl benzoate

A: 93-58-3
benzoic acid methyl ester

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With triethylamine at 20℃; under 8250660 Torr; for 2h; Product distribution;	A 100% B n/a

...Expand

: 546-68-9
titanium(IV) isopropylate

A: titanium(IV) oxide

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In gas byproducts: CH3CHCH2; decomposition at a pressure of ca. 0.01 mm of Hg at 700°C; org. compounds collected in a liquid-N2 trap; NMR; GC; mass spectra;	A n/a B 100%

: 25443-56-5
hexakis[μ-(2-propanolato)]hexakis(2-propanolato)tetraaluminum

: 107-96-0
3-mercaptopropionic acid

A: aluminium(isopropoxide)(OCOCH2CH2SH)2

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In benzene exclusion of moisture, addn. of 3-mercaptopropionic acid in benzene to Al(OiPr)3 in benzene (molar ratio 2:1), refluxing; elem. anal.;	A 100% B n/a

...Expand

: 110-85-0
piperazine

: 546-68-9
titanium(IV) isopropylate

: 3159-07-7
dibenzo[b,f][1,4]thiazepin-11-one

A: 5747-48-8
11-(1-piperazinyl)dibenzo[b,f][1,4]thiazepine

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
at 170℃; for 5h; Heating / reflux;	A 99% B n/a

...Expand

: 25443-56-5
hexakis[μ-(2-propanolato)]hexakis(2-propanolato)tetraaluminum

: 107-96-0
3-mercaptopropionic acid

A: aluminium(isopropoxide)2(OCOCH2CH2SH)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In benzene exclusion of moisture, addn. of 3-mercaptopropionic acid in benzene to Al(OiPr)3 in benzene (molar ratio 1:1), refluxing; elem. anal.;	A 99% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 3526-45-2
2-((phenylamino)methyl)phenol

A: (N-(phenyl)benzylamine-2-ato)-bis(8-quinolinato)-titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.7% B n/a

...Expand

: 4-bromo-2-((p-tolylamino)methyl)phenol

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

A: (N-(4-methylphenyl)-5-bromobenzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.6% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 7193-94-4
2-((4-chlorophenylamino)methyl)phenol

A: (N-(4-chlorophenyl)benzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.6% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 52537-88-9
N-(2-hydroxybenzyl)-p-anisidine

A: (N-(4-methoxyphenyl)benzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.4% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 132120-37-7
4-bromo-2-(((4-bromophenyl)amino)methyl)phenol

A: [(N-(4-bromophenyl)-5-bromobenzylamine-2-ato)-bis(8-quinolinato)titanium(IV)]

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.3% B n/a

...Expand

: 763132-62-3
4-bromo-2-(((4-methoxyphenyl)amino)methyl)phenol

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

A: (N-(4-methoxyphenyl)-5-bromobenzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.2% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 7166-37-2
2-(2-chloro-anilinomethyl)-phenol

A: (N-(2-chlorophenyl)benzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.2% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 14674-88-5
2-((p-toluidino)methyl)phenol

A: (N-(4-methylphenyl)benzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.1% B n/a

...Expand

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 61593-31-5
N-phenyl-N-2-hydroxy-5-bromobenzylamine

A: (N-(phenyl)-5-bromobenzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 98.1% B n/a

...Expand

: 110-86-1
pyridine

: Cl2Pt(C(OiPr)(Me))2

A: 75-29-6
isopropyl chloride

B: 1395411-06-9
cis-Cl(py)Pt(COMe)[C(OiPr)(Me)]

C: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In tetrahydrofuran-d8 at 55℃; for 21h;	A n/a B 98% C n/a

...Expand

: 1927-70-4
2-isopropoxytetrahydropyran

: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With methanol; boron trichloride In neat (no solvent) at 20℃; for 0.05h; Green chemistry;	98%

: 23329-69-3, 454677-87-3
cis-di-2-propanolato-bis(8-quinolinato)-titanium(IV)

: 1323851-44-0
4-bromo-2-(((2-bromophenyl)amino)methyl)phenol

A: (N-(2-bromophenyl)-5-bromobenzylamine-2-ato)-bis(8-quinolinato)titanium(IV)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In toluene at 100 - 120℃; for 4 - 5h; Heating;	A 97.8% B n/a

...Expand

: 25443-56-5
hexakis[μ-(2-propanolato)]hexakis(2-propanolato)tetraaluminum

: 68-11-1
mercaptoacetic acid

A: aluminiumtris(2-mercaptoacetate)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In benzene exclusion of moisture, addn. of 2-mercaptoacetic acid in benzene to Al(OiPr)3 in benzene (molar ratio 3:1), refluxing; elem. anal.;	A 96% B n/a

...Expand

: 546-68-9
titanium(IV) isopropylate

: 496-74-2
3,4-dimercaptotoluene

A: 126975-34-6
C13H20O2S2Ti

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In benzene N2-atmosphere; azeotropic distn. of i-PrOH, evapn. (reduced pressure), repeated dissoln. in petroleum, evapn. (reduced pressure);	A 95% B n/a

...Expand

: 187737-37-7
propene

: 64-19-7
acetic acid

A: 108-20-3
di-isopropyl ether

B: 108-21-4
Isopropyl acetate

C: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With water; cesium nitrate; tungstophosphoric acid; water; mixture of, dried, tabletted at 105.6 - 165℃; under 6750.68 Torr; Product distribution / selectivity; Gas phase;	A 2.3% B 94.7% C 2.8%

...Expand

: 25443-56-5
hexakis[μ-(2-propanolato)]hexakis(2-propanolato)tetraaluminum

: 68-11-1
mercaptoacetic acid

A: aluminium(isopropoxide)2(2-mercaptoacetate)

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In benzene exclusion of moisture, addn. of 2-mercaptoacetic acid in benzene to Al(OiPr)3 in benzene (molar ratio 1:1), refluxing (100°C bath temp.); slow evapn. (3 h), ppt. is filtered and dried under reduced pressure, elem. anal.;	A 94% B n/a

...Expand

: 25443-56-5
hexakis[μ-(2-propanolato)]hexakis(2-propanolato)tetraaluminum

: 68-11-1
mercaptoacetic acid

A: aluminium(isopropoxide)(2-mercaptoacetate)2

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
In benzene exclusion of moisture, addn. of 2-mercaptoacetic acid in benzene to Al(OiPr)3 in benzene (molar ratio 2:1), refluxing; elem. anal.;	A 93% B n/a

...Expand

: 769-42-6
1,3-dimethylbarbituric acid

: 67-64-1
acetone

A: 108-20-3
di-isopropyl ether

B: 7358-62-5
1,3-dimethyl-5-isopropylbarbituric acid

C: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
Stage #1: 1,3-dimethylbarbituric acid; acetone Stage #2: With sulfuric acid; hydrogen; platinum on activated charcoal In water under 3878.61 Torr; for 48h;	A n/a B 92% C n/a

...Expand

: 100-52-7
benzaldehyde

: 75-31-0
isopropylamine

: 98-86-2
acetophenone

A: 580-35-8
2,4,6-triphenylpyridine

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With diphenylammonium trifluoromethanesulfonate at 120℃; for 5h; Neat (no solvent); regioselective reaction;	A 92% B 90 %Chromat.

...Expand

: 57-55-6
propylene glycol

A: 71-23-8
propan-1-ol

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With hydrogen at 180℃; under 37503.8 Torr; Catalytic behavior; chemoselective reaction;	A 91.2% B 7.8%
With hydrogen In water at 179.84℃; under 22502.3 Torr; for 10h; Autoclave;	A 76% B 9%
With hydrogen In water at 130℃; under 30003 Torr; for 24h;

: 103-76-4
1-(2-hydroxyethyl)piperazine

: 546-68-9
titanium(IV) isopropylate

: 3159-07-7
dibenzo[b,f][1,4]thiazepin-11-one

A: 329216-67-3
O-Dealkyl Quetiapine

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
at 170℃; for 5.5h; Heating / reflux;	A 91% B n/a

...Expand

: 85-44-9
phthalic anhydride

: 67-63-0
isopropyl alcohol

: 35118-50-4
monoisopropyl phthalate

Conditions

Conditions	Yield
at 90℃; for 6h;	100%
for 6h; Reflux;	99%
With 1-hydro-3-(3-sulfopropyl)-imidazolium 4-methyl-benzenesulfonate at 60℃; Heating;	92%

: 150-13-0
4-amino-benzoic acid

: 67-63-0
isopropyl alcohol

: 18144-43-9
isopropyl 4-aminobenzoate

Conditions

Conditions	Yield
Stage #1: 4-amino-benzoic acid; isopropyl alcohol With thionyl chloride at 20℃; for 90h; Reflux; Stage #2: With sodium hydrogencarbonate In water; isopropyl alcohol	100%
With thionyl chloride; sodium carbonate for 2h; Heating;	89%
With hydrogenchloride

: 67-63-0
isopropyl alcohol

: 99-33-2
3,5-dinitrobenoyl chloride

: 10477-99-3
3,5-dinitro-benzoic acid isopropyl ester

Conditions

Conditions	Yield
With pyridine In tetrahydrofuran for 0.333333h; Heating;	100%
With diethyl ether
With pyridine; benzene

: 67-63-0
isopropyl alcohol

: 187737-37-7
propene

Conditions

Conditions	Yield
1 percent alumina-modified MCM-41 at 250℃; Product distribution; Further Variations:; Catalysts; Temperatures; Dehydration;	100%
With mesoporous silica MCM-4l/Al at 246.84℃; for 50h;	100%
With hydrogen at 174.84℃; for 6h; Catalytic behavior;	99.5%

: 67-63-0
isopropyl alcohol

: 75-29-6
isopropyl chloride

Conditions

Conditions	Yield
With indium(III) chloride; dimethylmonochlorosilane; benzil In dichloromethane at 20℃; for 6h;	100%
With priphenylchlorophosphonium phosphorodichloridate at 20℃; Arbuzov reaction;	84%
With hydrogenchloride at 120℃; under 7500.75 Torr; Flow reactor;	54%

: 67-63-0
isopropyl alcohol

: 67-64-1
acetone

Conditions

Conditions	Yield
With trans-4L1(O)2>ClO4 In acetonitrile at 25℃; for 7h; stoicheiometric oxidation ( electrochemical oxidation in a non-aqueous medium (acetonitrile), an Ag-AgNO3 reference electrode;	100%
With C19H20N3O2Ru(2+)*2F6P(1-) In aq. buffer at 24.84℃; for 1h; pH=1.8; Thermodynamic data; Activation energy; Reagent/catalyst;	100%
With tert-butylethylene; C32H52ClIrP2; sodium t-butanolate at 200℃; for 2h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Glovebox;	100%

: 96-09-3
styrene oxide

: 67-63-0
isopropyl alcohol

: 89101-31-5, 90332-91-5
2-isopropoxy-2-phenylethanol

Conditions

Conditions	Yield
With erbium(III) triflate at 25℃; for 1.5h;	100%
With ytterbium(III) triflate at 20℃; for 12h;	98%
With tin(IV)tetraphenylporphyrinato trifluoromethanesulfonate for 0.0833333h; Heating;	98%

: 100-39-0
benzyl bromide

: 67-63-0
isopropyl alcohol

: 937-54-2
benzyl isopropyl ether

Conditions

Conditions	Yield
Stage #1: isopropyl alcohol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h; Inert atmosphere; Stage #2: benzyl bromide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 5h; Inert atmosphere;	100%
With iron(II) sulfate at 75℃; for 12h;	92%
With silver(II) oxide Heating;	90%
With potassium hydroxide; tetrafluoroboric acid; mercury(II) oxide In dichloromethane 1.) room temp., 1 h;	60%
(i) Ag2O, (ii) Py, PhCOCl; Multistep reaction;

: 22065-57-2
ethyl 2-phenyldiazoacetate

: 67-63-0
isopropyl alcohol

: ethyl 2-isopropyloxyphenylacetate

Conditions

Conditions	Yield
With silver hexafluoroantimonate; C29H33AuClN3O2 In chloroform-d1 at 20℃;	100%
dirhodium tetraacetate In dichloromethane for 0.1h; Ambient temperature;	92%

: 622-58-2
p-Tolylisocyanate

: 67-63-0
isopropyl alcohol

: 36613-26-0
carbamic acid, (4-methylphenyl)-, 1-methylethyl ester

Conditions

Conditions	Yield
Ambient temperature;	100%
In dichloromethane at 20℃; for 4.5h; Inert atmosphere;	13 mg

: 4504-12-5
ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxaldehyde

: 67-63-0
isopropyl alcohol

: 142558-49-4, 142558-62-1
(Z)-2-Isopropoxy-3-phenylamino-acrylic acid ethyl ester

Conditions

Conditions	Yield
Irradiation; pyrex filter;	100%

: 2641-34-1
perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride

: 67-63-0
isopropyl alcohol

: 2'-perfluoropropoxy-2-perfluoropropoxyperfluoropropanoic acid isopropyl ester

Conditions

Conditions	Yield
at 20 - 30℃; for 1.5h; Inert atmosphere;	100%
With water for 1h; Ambient temperature;	85.5%
at 25 - 30℃; for 49h;

: 69352-25-6
ethyl 2-hydroxypyrrolidine-1-carboxylate

: 67-63-0
isopropyl alcohol

: 69352-23-4
2-isopropoxy-pyrrolidine-1-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With acetic acid	100%

: 85118-00-9
2,6-Difluorobenzyl bromide

: 67-63-0
isopropyl alcohol

: 1,3-Difluoro-2-isopropoxymethyl-benzene

Conditions

Conditions	Yield
With silver(II) oxide for 1h; Heating;	100%

: 54107-24-3
3-(2-vinyloxyethoxy)-1,2-propylene carbonate

: 67-63-0
isopropyl alcohol

: 126867-30-9
4-[2-(1-Isopropoxy-ethoxy)-ethoxymethyl]-[1,3]dioxolan-2-one

Conditions

Conditions	Yield
With heptafluorobutyric Acid at 20 - 45℃; for 3h;	100%

: 136862-04-9
2,3-di-O-benzoyl-L-(+)-tartaric anhydride

: 67-63-0
isopropyl alcohol

: 117655-09-1
isopropyl hydrogen 2,3-di-O-benzoyl-L-(+)-tartrate

Conditions

Conditions	Yield
In chloroform at 60℃; for 3h;	100%

: 67-63-0
isopropyl alcohol

: 78463-59-9
C19H55N3P2Si6

: C22H63N3OP2Si6

Conditions

Conditions	Yield
In diethyl ether for 1h;	100%

: 67-63-0
isopropyl alcohol

: 106137-28-4
exo-cis-7-oxabicyclo<2.2.1>hept-5-ene-2,3-dimethanol carbonate

: Carbonic acid (1S,2S,3R,4R)-3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-ylmethyl ester isopropyl ester

Conditions

Conditions	Yield
With toluene-4-sulfonic acid for 8h; Heating;	100%

: 67-63-0
isopropyl alcohol

: 100-46-9
benzylamine

: 102-97-6
Benzyl-isopropyl-amin

Conditions

Conditions	Yield
With C13H20N2O*Ir(1+); hydrogen at 80℃; under 3000.3 Torr; for 23h; Reagent/catalyst; Autoclave; Green chemistry;	100%
With nickel at 20℃; for 26h;	70%
Pt on TiO2 for 10h; Ambient temperature; Irradiation;	36.32%

: 90357-89-4
2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl trichloroacetimidate

: 67-63-0
isopropyl alcohol

: 151909-91-0
isopropyl 2,3,4,6-tetra-O-benzyl-D-glucopyranoside

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; 1-ethyl-3-methylimidazolium triflate at 20℃; for 0.333333h;	100%
With 1-ethyl-3-methylimidazolium triflate at 20℃;	100%
With molecular sieve; lithium perchlorate In dichloromethane at 25℃;	96%

: 4025-77-8
chlorosulfonylacetyl chloride

: 67-63-0
isopropyl alcohol

: 303153-12-0
isopropyl (chlorosulfonyl)acetate

Conditions

Conditions	Yield
In diethyl ether at 0℃; Esterification;	100%
In tetrahydrofuran at 0℃; for 0.333333h;	100%
In dichloromethane
In diethyl ether
In tetrahydrofuran at 0 - 20℃; for 2.33333h; Inert atmosphere;

: 67-63-0
isopropyl alcohol

: 51963-59-8
isopropyl hypophosphite

Conditions

Conditions	Yield
With triethylammonium phosphinate In dichloromethane at 20℃; for 0.166667h;	100%
With hypophosphorous acid In benzene for 15h; Dean-Stark; Inert atmosphere; Reflux;	100%
With pyrophosphorous acid In benzene Heating;	100 % Spectr.

: 33647-88-0
(R)-5-oxo-5,6-dihydro-2H-pyran-2-yl acetate

: 67-63-0
isopropyl alcohol

: 6-isopropoxy-6H-pyran-3-one

Conditions

Conditions	Yield
With palladium diacetate; triphenylphosphine at 20℃; for 1h;	100%

: 67-63-0
isopropyl alcohol

: 210989-55-2
trans 4-(bromomethyl)-2-methoxy-1,3-dioxolane

: 210989-56-3
trans 4-(bromomethyl)-2-isopropoxy-1,3-dioxolane

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In benzene at 90℃;	100%

: 2033-24-1
cycl-isopropylidene malonate

: 67-63-0
isopropyl alcohol

: 56766-77-9
i-propyl malonic half ester

Conditions

Conditions	Yield
In acetonitrile for 22h; Heating;	100%
Reflux;	76%
In toluene for 5h; Heating;

: 67-63-0
isopropyl alcohol

: 302-72-7
rac-Ala-OH

: iso-propyl alaninate hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at -20℃; for 4h; Heating / reflux;	100%
With thionyl chloride for 16h; Heating;

: 67-63-0
isopropyl alcohol

: 356055-89-5
3-phenylsulfanyl-butyric acid 4-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-benzyl ester

: 3-phenylsulfanyl-butyric acid isopropyl ester

Conditions

Conditions	Yield
With titanium(IV) isopropylate for 6h; Heating;	100%

: 67-63-0
isopropyl alcohol

: 356055-96-4
3-(4-tert-butyl-phenylsulfanyl)-hexanoic acid 4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-benzyl ester

: 3-(4-tert-butyl-phenylsulfanyl)-hexanoic acid isopropyl ester

Conditions

Conditions	Yield
With titanium(IV) isopropylate for 6h; Heating;	100%

: 67-63-0
isopropyl alcohol

: 356055-88-4
4-(2-perfluorodecyl)ethylbenzyl 2-methyl-3-phenylthiopropanoate

: 1-methylethyl 2-methyl-3-phenylthiopropanoate

Conditions

Conditions	Yield
With titanium(IV) isopropylate for 6h; Heating;	100%

Isopropanol Specification

Isopropanol, also known as isopropyl alcohol, is a colorless, flammable liquid with with a characteristic alcohol / acetone-like odor. It has an isomer propanol. And it is miscible with water, ethanol, ether and chloroform. Because the alcohol is much less soluble in saline solutions than in salt-free water, add a salt such as sodium chloride, sodium sulfate, or any of several other inorganic salts can separate the isopropanol from aqueous solutions.

Physical properties about Isopropanol are: (1)ACD/LogP: 0.173; (2)ACD/LogD (pH 5.5): 0.17; (3)ACD/LogD (pH 7.4): 0.17; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 29.59; (7)ACD/KOC (pH 7.4): 29.59; (8)#H bond acceptors: 1; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 1; (11)Index of Refraction: 1.376; (12)Molar Refractivity: 17.441 cm³; (13)Molar Volume: 75.938 cm³; (14)Polarizability: 6.914 10-24cm³; (15)Surface Tension: 22.6280002593994 dyne/cm; (16)Density: 0.791 g/cm³; (17)Flash Point: 11.667 °C; (18)Enthalpy of Vaporization: 39.85 kJ/mol; (19)Boiling Point: 72.993 °C at 760 mmHg; (20)Vapour Pressure: 81.3320007324219 mmHg at 25°C

Preparation of Isopropanol: Isopropanol is produced by combining water and propene. This technology has two processes: direct hydration and indirect hydration via the sulfuric acid process.

1. Direct hydration: Use propylene as raw material, phosphoric acid diatomite as catalytic agent, then directly hydrate under the pressure to obtain isopropanol. Propylene and water are pressurized to 2.03 MPa, and preheat to 200 °C, respectively. After mixing, the mixture goes into the reactor to go through hydration reaction. The reactor is equipped with phosphoric acid diatomite catalyst with the reaction temperature of 95 °C and pressure of 2.03 MPa. The molar ratio of water and propylene is 0.7:1. The percent conversion of propylene is 5.2% and the selectivity is 99%. Then, after neutralization and heat transfer, the reaction gas is sent to high pressure chiller and high pressure separator. The isopropanol in gas phase is recoveried and unreacted gas is recycled by recyclingcompressor. The liquid phase is low concentration isopropanol (15% - 17%). After a series of treatment, the yield can achieve 99%. This method does not need sulfuric acid, so there is no corrosion problem. And the process is relatively simple.

2. Indirect hydration: Using propylene which contains more than 50% as raw material. At low pressure and temperature of 50 °C, use 75%-85% sulfuric acid to absorb in absorption tower. The absorption solution is diluted to 35%, which is hydrolysised to isopropanol in desorption tower by low-pressure steam. The percent conversion of propylene is above 90%. This method needs sulfuric acid, so the corrosion to equipment is large.

Uses of Isopropanol: Isopropanol is widely used as organic feedstock and solvent. As chemical feedstock, it can be used to produce acetone, hydrogen peroxide, methyl isobutyl ketone, diisobutyl ketone, isopropyl, isopropyl ether, isopropyl ether, isopropyl chloride, etc. In industry of fine chemicals, it is used to produce nitric acid, xanthalato isopropyl, medicine, pesticide, etc. As a solvent, isopropanol can be used to produce paints, inks, extraction agents, aerosol agents, etc. It is also used as antifreeze, detergent, dispersant of pigment production, fixative of printing and dyeing industry, anti-fog agent of glass and transparent plastic. What's more, isopropanol is used as reagent in the determination of barium, calcium, copper, magnesium, nickel, potassium, sodium, strontium, nitrite and cobalt. Isopropanol is often used for the cleaning of electrical parts, for hi-fi equipment and for computers and computer-related equipment such as computer monitor screens, laptops and keyboards.

When you are using this chemical, please be cautious about it as the following: Isopropanol is irritating to eyes and skin. And its vapours may cause drowsiness and dizziness. You should wear suitable protective clothing and gloves to avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. When mixed with air or other oxidizers it can explode through deflagration.

You can still convert the following datas into molecular structure:
1. Smiles:C(C)(C)O
2. InChI:InChI=1/C3H8O/c1-3(2)4/h3-4H,1-2H3

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	1963mg/kg (1963mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 172, 1955.
cat	LDLo	oral	6mL/kg (6mL/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 26, Pg. 285, 1921.
dog	LDLo	intravenous	1024mg/kg (1024mg/kg)		Journal of Laboratory and Clinical Medicine. Vol. 29, Pg. 561, 1944.
dog	LDLo	oral	1537mg/kg (1537mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Laboratory and Clinical Medicine. Vol. 29, Pg. 561, 1944.
frog	LDLo	parenteral	20gm/kg (20000mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.
guinea pig	LD50	intraperitoneal	2560mg/kg (2560mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
hamster	LD50	intraperitoneal	3444mg/kg (3444mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
human	LDLo	oral	3570mg/kg (3570mg/kg)	BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: NAUSEA OR VOMITING	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 339, 1969.
human	LDLo	unreported	2mL/kg (2mL/kg)		Japanese Journal of Toxicology. Vol. 12, Pg. 341, 1999.
human	TDLo	oral	223mg/kg (223mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" CARDIAC: PULSE RATE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Journal of Laboratory and Clinical Medicine. Vol. 12, Pg. 326, 1927.
infant	TDLo	oral	13gm/kg (13000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: IRRITABILITY GASTROINTESTINAL: NAUSEA OR VOMITING	American Journal of Emergency Medicine. Vol. 10, Pg. 542, 1992.
infant	TDLo	unreported	1375mg/kg (1375mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Pediatric Emergency Care. Vol. 9, Pg. 146, 1993.
mammal (species unspecified)	LDLo	subcutaneous	6gm/kg (6000mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC	Archiv fuer Toxikologie. Vol. 16, Pg. 84, 1956.
man	LDLo	oral	5272mg/kg (5272mg/kg)	BEHAVIORAL: COMA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA	American Journal of Clinical Pathology. Vol. 38, Pg. 144, 1962.
man	LDLo	unreported	2770mg/kg (2770mg/kg)		"Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man	TDLo	oral	14432mg/kg (14432mg/kg)	BEHAVIORAL: COMA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA	New England Journal of Medicine. Vol. 277, Pg. 699, 1967.
mouse	LCLo	inhalation	12800ppm/3H (12800ppm)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
mouse	LD50	intraperitoneal	4477mg/kg (4477mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse	LD50	intravenous	1509mg/kg (1509mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse	LD50	oral	3600mg/kg (3600mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(1), Pg. 8, 1978.
mouse	LDLo	subcutaneous	6gm/kg (6000mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 172, 1955.
rabbit	LD50	intraperitoneal	667mg/kg (667mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit	LD50	intravenous	1184mg/kg (1184mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit	LD50	oral	6410mg/kg (6410mg/kg)		FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 114, 1970.
rabbit	LD50	skin	12800mg/kg (12800mg/kg)		Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 100, 1974.
rat	LC50	inhalation	16000ppm/8H (16000ppm)		Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 100, 1974.
rat	LD50	intraperitoneal	2735mg/kg (2735mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat	LD50	intravenous	1088mg/kg (1088mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat	LD50	oral	5045mg/kg (5045mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(1), Pg. 8, 1978.

Product Name

Isopropanol

Synthetic route

Isopropanol Specification

Related Products

Hot Products