L-Phenylglycinol supplier | CasNO.3182-95-4

Name
L-Phenylglycinol
EINECS 221-674-4
CAS No. 3182-95-4
Article Data210
CAS DataBase
Density 1.077 g/cm³
Solubility
Melting Point 92-94 °C(lit.)
Formula C₉H₁₃NO
Boiling Point 303.8 °C at 760 mmHg
Molecular Weight 151.208
Flash Point 137.5 °C
Transport Information UN 3259 8/PG 3
Appearance white to light yellow crystal powder
Safety 26-36/37/39-45-24/25-27
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms 1-Propanol, 2-amino-3-phenyl-, L-;(S)-beta-Aminobenzenepropanol;(S)-2-Benzylethanolamine;[(2S)-1-hydroxy-3-phenyl-propan-2-yl]azanium;2-amino-3-phenyl-propan-1-ol;L-2-Amino-3-phenylpropan-1-ol;L-2-Amino-3-phenyl-1-propanol;L-Phenylalainol;(R)/(S)-Phenylalaninol;L(-)-2-Amino-3-phenyl-1-propanol;L-(-)-Phenylalaninol;L- Phenylalaninol;(S)-(-)-2-amino-3-phenyl-1-propanol (L-phenylalaninol);L-(S)-Phenylalaninol;(S)-(-)-2-Amino-3-phenyl-1-propanol;(S)-2-amino-3-phenyl-1-propanol;H-Phe-ol;L(-)-Phenylalaninol;H-Phenylalaninol;Benzenepropanol, beta-amino-, (S)- (9CI);L-Phenylalaninol;S-Phenylalaninol;L-2-Phenylalaninol;
PSA 46.25000
LogP 1.24900

Synthetic route

: 63-91-2
L-phenylalanine

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran Heating;	100%
With lithium borohydride; chloro-trimethyl-silane In tetrahydrofuran at 0 - 20℃; for 16h;	99%
With sodium tetrahydroborate; iodine In tetrahydrofuran at 0℃; for 18.5h; Inert atmosphere; Reflux;	99%

: 2577-90-4
methyl (2S)-2-amino-3-phenylpropanoate

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate; diborane In tetrahydrofuran at 20℃; for 1h;	100%
With hydrogen In ethanol at 110℃; under 30003 Torr; Reagent/catalyst; Autoclave; chemoselective reaction;	91.1%
With lithium aluminium tetrahydride In tetrahydrofuran for 4h; Heating;	86%

: C9H9(2)H4NO2*C2HF3O2

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With sodium tetrahydroborate at 23℃; for 2160h; Reduction;	99%

: 6372-14-1
N-((benzyloxy)carbonyl)-L-phenylalaninol

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With ammonium formate; palladium on activated charcoal In methanol for 0.0833333h;	98%
With hydrogen; palladium on activated charcoal In tetrahydrofuran; methanol under 760 Torr; for 3h; Ambient temperature;

: 129397-83-7
(9-fluorenylmethoxycarbonyl)-L-phenylalaninol

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With piperidine In dichloromethane for 1h; Ambient temperature;	85%

: C10H12(2)H3NO2*C2HF3O2

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With sodium tetrahydroborate at 23℃; for 120h; Reduction;	85%

: 2935-35-5
(S)-2-phenylglycine

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 18h; Reflux;	85%

: 207676-65-1
(-)-3-[2-(1-hydroxy-3-phenylpropyl)]-4-phenyloxazolidin-2-one

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With ammonia; lithium at -78℃; for 0.0833333h;	81%

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 100℃; for 72h;	80%

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol 1.) room temperature, 4 h, 2.) reflux, 6 h, 3.) room temperature, overnight;	78%
With sodium tetrahydroborate In ethanol; water for 18h; Heating;	74%
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With triethylamine In methanol; diethyl ether at -10℃; for 1h; Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃;	2.72 g
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With sodium tetrahydroborate In water at 0 - 5℃; for 16h; Stage #2: With hydrogenchloride In water pH=5; Stage #3: With sodium hydroxide In water for 3h; Reflux;	50 g

: 66605-57-0
(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With sodium dodecyl-sulfate; benzyl bromide In water at 45 - 50℃; for 48h; chemoselective reaction;	76%
With trifluoroacetic acid Substitution;
In trifluoroacetic acid for 0.5h;
With trifluoroacetic acid In dichloromethane

: 3182-93-2
(L)-phenylalanine ethyl ester hydrochloride

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol; water for 4.5h; Reflux;	72%
With sodium tetrahydroborate In ethanol for 5.5h; Heating;	71.7%
With sodium tetrahydroborate In ethanol
With sodium tetrahydroborate In ethanol; water for 4h; Heating; Yield given;
With sodium tetrahydroborate In ethanol; water for 4.5h; Reflux;	19.16 g

: 912480-01-4
(S)-dibenzyl 1-(1-hydroxy-3-phenylpropan-2-yl)-hydrazine-1,2-dicarboxylate

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With hydrogen; nickel; acetic acid In methanol at 20℃; under 3102.97 Torr; for 16h;	70%

: 2862-51-3
(3S,6S)-3,6-dibenzylpiperazine-2,5-dione

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With C24H20ClN2OPRu; potassium tert-butylate; hydrogen In tetrahydrofuran at 110℃; under 2280.15 - 30402 Torr; for 48h; Catalytic behavior; Solvent; Pressure; Temperature; Inert atmosphere; Schlenk technique; Autoclave;	63%

: 58745-46-3
(S)-N-(1-hydroxy-3-phenylpropan-2-yl)picolinamide

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
Stage #1: (S)-N-(1-hydroxy-3-phenylpropan-2-yl)picolinamide With hydrogenchloride In water at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: With zinc In water at 20℃; for 16h; Inert atmosphere;	60%

: 123366-90-5
(S)-3-phenyl-2-(1H-pyrrol-1-yl)propan-1-ol

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
Stage #1: (S)-3-phenyl-2-(1H-pyrrol-1-yl)propan-1-ol With ozone In methanol at -78℃; for 2.5h; Stage #2: With thiourea In methanol at 0 - 78℃; for 1.5h; Reagent/catalyst; Solvent; Inert atmosphere;	60%

: 17585-69-2, 27172-85-6, 28069-46-7, 74496-49-4, 79541-99-4
L-phenylalanine hydrochloride

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 12h; Reflux; Inert atmosphere;	46.1%

: 4982-08-5
1-hydroxy-3-phenylpropan-2-one

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With ammonium hydroxide; ammonium acetate; AmDHK78S/N276T In water at 40℃; for 24h; pH=9; Enzymatic reaction;	41%

: 63-91-2
L-phenylalanine

A: 3182-95-4
L-Phenylalaninol

B: (2S)-(-)-2-amino-3-phenylpropan-1-ol N-borane

Conditions

Conditions	Yield
Stage #1: L-phenylalanine With sodium tetrahydroborate; sulfuric acid In tetrahydrofuran; diethyl ether at 0 - 20℃; for 20h; Inert atmosphere; Stage #2: With hydrogenchloride In water at 20℃; for 2h;	A 26% B 36%

: 3182-93-2
(L)-phenylalanine ethyl ester hydrochloride

A: 3182-95-4
L-Phenylalaninol

B: 5267-64-1
(R)-2-amino-3-phenylpropanol

Conditions

Conditions	Yield
With methanol; Na/SiO2 In tetrahydrofuran at 0 - 25℃; Bouveault-Blanc reduction; Inert atmosphere; optical yield given as %ee;	A 27% B n/a

: 1795-98-8, 3182-95-4, 5267-64-1, 16088-07-6
rac-phenylalaninol

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
Stage #1: rac-phenylalaninol With O,O'-dibenzoyl-L-tartaric acid In acetone at 25℃; for 6h; Stage #2: With potassium hydroxide In dichloromethane	24%

: 3081-24-1
H-Phe-OEt

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride; diethyl ether
With lithium aluminium tetrahydride In diethyl ether
With lithium aluminium tetrahydride
With sodium tetrahydroborate In ethanol; water

: N-Benzoyl-Gly-L-Phe-ethylester

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
(i) aq. NaBH4, (ii) (hydrolysis); Multistep reaction;

: 91339-66-1
(S)-(-)-2-amino-1-hydroxy-3-phenylpropane ethyl ester hydrochloride

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol; water for 4h; Heating; Yield given;

: 162334-17-0
L-phenylalaninol hexanoate

A: 3182-95-4
L-Phenylalaninol

B: 142-62-1
hexanoic acid

Conditions

Conditions	Yield
With α-chymotrypsin chemically modified with monomethoxypolyethylene glycol (α-CT-PEG) Rate constant; enzymatic hydrolysis at pH 8.0 (phosphate buffer), Km value;

: 162334-16-9
L-phenylalaninol phenylacetate

A: 103-82-2
phenylacetic acid

B: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With α-chymotrypsin chemically modified with monomethoxypolyethylene glycol (α-CT-PEG) Rate constant; enzymatic hydrolysis at pH 8.0 (phosphate buffer), Km value;

: 2-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-cyclopent-1-enecarbonitrile

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With hydrogenchloride In water at 85 - 90℃; for 48h; Yield given;

: (Z)-3-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-2-phenyl-acrylonitrile

: 3182-95-4
L-Phenylalaninol

Conditions

Conditions	Yield
With hydrogenchloride In water at 85 - 90℃; for 48h;

: 2577-90-4
methyl (2S)-2-amino-3-phenylpropanoate

A: 3182-95-4
L-Phenylalaninol

B: 131288-67-0
(2S)-2-amino-3-cyclohexyl-1-propanol

Conditions

Conditions	Yield
With hydrogen; Nishimura catalyst <(45.9% Rh/19.9% Pt) oxide> In methanol at 25℃; under 75007.5 Torr;	A 40 % Spectr. B 40 % Spectr.

: 24424-99-5
di-tert-butyl dicarbonate

: 3182-95-4
L-Phenylalaninol

: 66605-57-0
(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol

Conditions

Conditions	Yield
In dichloromethane Acylation;	100%
In ethanol at 20℃;	100%
In water at 30 - 35℃; for 1h;	100%

: 303-45-7
(rac)-gossypol

: 3182-95-4
L-Phenylalaninol

: 8,8'-Bis-((S)-4-benzyl-oxazolidin-2-yl)-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-1,6,7,1',6',7'-hexaol

Conditions

Conditions	Yield
In methanol for 5h; Ambient temperature;	100%

: 3182-95-4
L-Phenylalaninol

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 88084-14-4
benzyl 2-[(1-benzyl-2-hydroxyethyl)carbamoyl]pyrrolidine-1-carboxylate

Conditions

Conditions	Yield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 25℃; for 2.5h;	100%
Stage #1: N-Benzyloxycarbonyl-L-proline With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran; N,N-dimethyl-formamide at -9 - -5℃; for 0.1h; Stage #2: L-Phenylalaninol In tetrahydrofuran; N,N-dimethyl-formamide at -5 - 20℃; for 20h; Solvent; Temperature; Reagent/catalyst;	95%
With 4-methyl-morpholine; chloroformic acid ethyl ester In ethyl acetate at -15 - 20℃; for 15h; Inert atmosphere; Schlenk technique;	75%
Stage #1: N-Benzyloxycarbonyl-L-proline With TEA; chloroformic acid ethyl ester In tetrahydrofuran at 0℃; for 0.5h; Stage #2: L-Phenylalaninol In tetrahydrofuran for 20h;

: 3182-95-4
L-Phenylalaninol

: 105-58-8
Diethyl carbonate

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

Conditions

Conditions	Yield
With potassium carbonate In ethyl acetate at 120 - 130℃; for 3h;	100%
With potassium carbonate In ethanol at 130 - 135℃; for 1h;	88%
With potassium carbonate at 135 - 140℃; for 2h;	84%

: 85-44-9
phthalic anhydride

: 3182-95-4
L-Phenylalaninol

: 70451-01-3
(-)-(S)-2-(1-benzyl-2-hydroxyethyl)-1H-isoindole-1,3(2H)-dione

Conditions

Conditions	Yield
With triethylamine In toluene at 145℃; for 41h;	100%
With triethylamine In toluene for 3h; Condensation; Heating;	96%
at 200℃; for 3h;	94%

: 3182-95-4
L-Phenylalaninol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 221045-94-9
(S)-(-)-2-amino-3-phenyl-1-(tert-butyldimethylsilyloxy)propane

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 20℃; for 21h; Substitution;	100%
With triethylamine In dichloromethane at 20℃; for 24h; Inert atmosphere; Cooling;	89%
With dmap; triethylamine In dichloromethane at 20℃;	88%

: 3182-95-4
L-Phenylalaninol

: 99-63-8
benzene-1,3-dicarbonyl dichloride

: 475110-10-2
N1,N3-bis[(S)-1-hydroxy-3-phenylpropan-2-yl]isophthalamide

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 20℃; for 12h;	100%
With triethylamine In dichloromethane at 0 - 25℃; for 8h;	70%
With triethylamine In dichloromethane at 0 - 20℃;	53%

: 89-95-2
2-methyl-benzyl alcohol

: 3182-95-4
L-Phenylalaninol

: 850449-41-1
2-{[(E)-(S)-1-Hydroxymethyl-2-phenyl-ethylimino]-methyl}-phenol

Conditions

Conditions	Yield
With sodium sulfate In methanol for 12h; Heating;	100%
In ethanol at 20℃;
With magnesium sulfate In methanol Heating;
In methanol

: 3182-95-4
L-Phenylalaninol

: 839697-82-4
3-(triisopropylsilyl)propiolic acid

: 839698-01-0
(1S)-3-(triisopropylsilanyl)propynoic acid (1-benzyl-2-hydroxyethyl)amide

Conditions

Conditions	Yield
With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 20h;	100%

: 7321-55-3
2,2-dimethylmalononitrile

: 3182-95-4
L-Phenylalaninol

: 176706-98-2
(4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]

Conditions

Conditions	Yield
With zinc trifluoromethanesulfonate In toluene for 48h; Heating;	100%
With zinc(II) chloride In chlorobenzene for 24h; Inert atmosphere; Reflux;	75%
With zinc(II) chloride In chlorobenzene for 72h; Reflux;	24%

: 3182-95-4
L-Phenylalaninol

: 63808-36-6
(2S)-2-cyanopyrrolidine-1-carboxylic acid benzyl ester

: 700875-99-6
(2S)-2-{(4S)-4-benzyl-4,5-dihydro-1,3-oxazol-2-yl}pyrrolidine-1-carboxylic acid benzyl ester

Conditions

Conditions	Yield
With zinc(II) chloride In chlorobenzene Heating;	100%

: 3182-95-4
L-Phenylalaninol

: 50777-76-9
(2-formylphenyl)(diphenyl)phosphine

: 202345-92-4
(S)-2-(2-(diphenylphosphino)benzylideneamino)-3-phenylpropan-1-ol

Conditions

Conditions	Yield
With sodium sulfate In ethanol Heating;	100%

: 7623-09-8
2-chloropropionyl chloride

: 3182-95-4
L-Phenylalaninol

: 1048970-96-2
C15H19Cl2NO3

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 16h;	100%

: 383-63-1
ethyl trifluoroacetate,

: 3182-95-4
L-Phenylalaninol

: 64889-55-0
(S)-2,2,2-trifluoro-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide

Conditions

Conditions	Yield
In methanol at 20℃; for 2.5h;	100%

: 34619-03-9
tert-butyldicarbonate

: 3182-95-4
L-Phenylalaninol

: 66605-57-0
(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol

Conditions

Conditions	Yield
With sodium hydroxide In dichloromethane; water at 20℃; for 24h;	100%

: 20632-57-9
3-[(phenylcarbamoyl)amino]benzoic acid

: 3182-95-4
L-Phenylalaninol

: (S)-N-(1-hydroxy-3-phenylpropan-2-yl)-3-(3-phenylureido)benzamide

Conditions

Conditions	Yield
Stage #1: 3-[(phenylcarbamoyl)amino]benzoic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.5h; Inert atmosphere; Stage #2: L-Phenylalaninol In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;	100%

: 3182-95-4
L-Phenylalaninol

: C37H37O2P

: C46H48NO2P

Conditions

Conditions	Yield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; Inert atmosphere; Cooling with ice;	100%

: 6340-79-0
4-(4-bromophenyl)-4-oxo-butyric acid

: 3182-95-4
L-Phenylalaninol

: (3S,7aS)-3-benzyl-7a-(4-bromophenyl)tetrahydropyrrolo[2,1-b]oxazol-5(6H)-one

Conditions

Conditions	Yield
In toluene Reflux; Dean-Stark; stereoselective reaction;	99.8%

: 553-90-2
Dimethyl oxalate

: 3182-95-4
L-Phenylalaninol

: 19071-60-4, 133464-01-4
(S)-N,N'-bis<1-(hydroxymethyl)-2-phenylethyl>ethanediamide

Conditions

Conditions	Yield
In methanol at 20℃; for 0.583333h;	99%
In methanol at 20℃; for 0.5h;	99%
In methanol at 20℃; for 0.0833333h;	99%

: 75-15-0
carbon disulfide

: 3182-95-4
L-Phenylalaninol

: 131744-19-9, 145588-94-9
(4S)-4-benzyl-1,3-oxazolidine-2-thione

Conditions

Conditions	Yield
With dihydrogen peroxide; potassium carbonate In ethanol at 50℃;	99%
With 2-chloro-1,3-dimethylimidazolinium chloride; triethylamine In dichloromethane at 20℃; for 20h; Condensation; Cyclization;	98%
With dihydrogen peroxide; potassium carbonate In ethanol at 50℃; for 0.0833333h;	98%

: 3182-95-4
L-Phenylalaninol

: 100431-28-5
1-chloro-2(S)-amino-phenylpropane hydrochloride

Conditions

Conditions	Yield
With thionyl chloride In N,N-dimethyl-formamide at 120℃; for 2h;	99%
With hydrogenchloride; thionyl chloride

: 3182-95-4
L-Phenylalaninol

: 79-22-1
methyl chloroformate

: 10289-05-1
N-[(1S)-2-Hydroxy-1-benzylethyl]methoxy carboxamide

Conditions

Conditions	Yield
With potassium carbonate In methanol at 20℃; Acylation;	99%
With potassium carbonate In tetrahydrofuran; water at 0 - 20℃; for 2.16667h; Yield given;

: 3182-95-4
L-Phenylalaninol

: 100-39-0
benzyl bromide

: 111060-52-7
(S)-2-(dibenzylamino)-3-phenylpropan-1-ol

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 0℃; for 0.333333h;	99%
With potassium carbonate In ethanol; water for 0.5h; Reflux;	96%
Stage #1: L-Phenylalaninol With potassium carbonate In methanol; water for 0.166667h; Reflux; Stage #2: benzyl bromide In methanol; water for 1h; Heating;	93%

: 14371-10-9
(E)-3-phenylpropenal

: 3182-95-4
L-Phenylalaninol

: 216306-33-1
(S,2E)-2-((E)-3-phenylallylideneamino)-3-phenylpropan-1-ol

Conditions

Conditions	Yield
In diethyl ether for 1.33333h; Ambient temperature;	99%
With magnesium sulfate In dichloromethane at 20℃; for 0.333333h;	99%

: 3182-95-4
L-Phenylalaninol

: 208051-70-1
2-methyl-4-methoxy-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide

: 208051-74-5
N-(2-methyl-4-methoxy-2H-1,2-benzothiazine-3-carbonyl)-L-phenylalaninol 1,1-dioxide

Conditions

Conditions	Yield
With 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol	99%

: 5535-48-8
PVS

: 3182-95-4
L-Phenylalaninol

: 640296-86-2
(S)-3-phenyl-2-((2-(phenylsulfonyl)ethyl)amino)propan-1-ol

Conditions

Conditions	Yield
In isopropyl alcohol for 48h; Heating;	99%

: 3182-95-4
L-Phenylalaninol

: 933-88-0
ortho-toluoyl chloride

: 497954-01-5
(2S)-2-o-toluamide-3-phenylpropanol

Conditions

Conditions	Yield
With potassium hydroxide In dichloromethane at 0 - 20℃;	99%
With triethylamine In tetrahydrofuran for 1h;

L-Phenylglycinol Chemical Properties

Molecular structure of L-Phenylglycinol (CAS NO.3182-95-4) is:

Product Name: L-Phenylglycinol
CAS Registry Number: 3182-95-4
IUPAC Name: 2-amino-3-phenylpropan-1-ol
Molecular Weight: 151.20562 [g/mol]
Molecular Formula: C₉H₁₃NO
XLogP3: 0.7
H-Bond Donor: 2
H-Bond Acceptor: 2
EINECS: 221-674-4
Melting Point: 92-94 °C(lit.)
Storage temp.: -15 °C
Sensitive: Air Sensitive
Surface Tension: 46.6 dyne/cm
Density: 1.077 g/cm³
Flash Point: 137.5 °C
Enthalpy of Vaporization: 57.46 kJ/mol
Boiling Point: 303.8 °C at 760 mmHg
Vapour Pressure: 0.0004 mmHg at 25°C
Product Categories: Pharmaceutical Intermediates;Amino Alcohols;chiral;Chiral Reagent;Phenylalanine [Phe, F];Amino Alcohols (Chiral);Chiral Building Blocks;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry;Amino alcohols;Benzene derivatives

L-Phenylglycinol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD	oral	> 1gm/kg (1000mg/kg)		Journal of Medicinal Chemistry. Vol. 11, Pg. 854, 1968.
mouse	LD50	intraperitoneal	76mg/kg (76mg/kg)		Journal of Medicinal Chemistry. Vol. 20, Pg. 1578, 1977.

L-Phenylglycinol Safety Profile

Safty information about L-Phenylglycinol (CAS NO.3182-95-4) is:
Hazard Codes: Corrosive C
Risk Statements: 34
R34:Causes burns.
Safety Statements: 26-36/37/39-45-24/25-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S24/25:Avoid contact with skin and eyes.
S27:Take off immediately all contaminated clothing.
RIDADR: UN 3259 8/PG 3
WGK Germany: 3
RTECS: UA6900000
F: 10-23
HS Code: 29221980

L-Phenylglycinol Specification

L-Phenylglycinol , its cas register number is 3182-95-4. It also can be called (S)-2-Benzylethanolamine ; (S)-beta-Aminobenzenepropanol ; L-2-Amino-3-phenyl-1-propanol ; S-Phenylalaninol ; 1-Propanol, 2-amino-3-phenyl-, L- ; Benzenepropanol, beta-amino-, (S)- (9CI) ; L-2-Amino-3-phenylpropan-1-ol .It is a white to light yellow crystal powder.

Product Name

L-Phenylglycinol

Synthetic route

L-Phenylglycinol Chemical Properties

L-Phenylglycinol Toxicity Data With Reference

L-Phenylglycinol Safety Profile

L-Phenylglycinol Specification

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