Lactonitrile supplier | CasNO.78-97-7

Name
Lactonitrile
EINECS 201-163-2
CAS No. 78-97-7
Article Data66
CAS DataBase
Density 0.991
Solubility
Melting Point -40.15°C
Formula C3H5 N O
Boiling Point 90 ºC (17 mmHg)
Molecular Weight 71.0788
Flash Point 77 °C
Transport Information UN 3276
Appearance Straw colored liquid.
Safety Poison by ingestion, skin contact, and subcutaneous routes. Moderately toxic by inhalation. In the presence of alkali, it evolves HCN. Combustible when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use foam, CO₂, dry chemical. When heated to decomposition it emits toxic fumes of CN⁻ and NO_x. See also NITRILES.
Risk Codes R23/25;R27
Molecular Structure
Hazard Symbols
Synonyms Lactonitrile(6CI,7CI,8CI); (?à)-2-Hydroxypropanenitrile;(?à)-2-Hydroxypropionitrile;2-Hydroxypropanenitrile; 2-Hydroxypropionitrile; Acetaldehyde, cyanohydrin;Acetocyanohydrin; NSC 7764; a-Hydroxypropionitrile
PSA 44.02000
LogP -0.10922

Synthetic route

: 74-90-8
hydrogen cyanide

: 75-07-0
acetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With triethylamine at 5 - 10℃; Product distribution / selectivity;	99%
With triethylamine at 0 - 10℃; pH=2 - 3;	99.54%
With sodium acetate; acetic acid; 2-hydroxy-propionitrile

: 151-50-8
potassium cyanide

: 75-07-0
acetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With sodium hydrogensulfite In water at 0℃; for 2h;	80%
With acetic acid In diethyl ether; water	22%

: 114711-04-5
2-[(tert-butyldimethylsilyl)oxy]propanenitrile

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With P(MeNCH2CH2)3N In dimethyl sulfoxide at 80℃; for 19h; desilylation;	80%

: 7677-24-9
trimethylsilyl cyanide

: 75-07-0
acetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With ytterbium(III) chloride; 2,6-bis[4′-isopropyloxazolin-2′-yl]pyridine In acetonitrile for 2h; Ambient temperature;	61%
With hydrogenchloride

: 107-13-1
acrylonitrile

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With tetrachloromethane; copper(II) choride dihydrate; chromium(III) acetylacetonate; water at 110℃; for 6h; Sealed tube;	46%
With acetic acid; lithium iodide In [D3]acetonitrile at 20℃; for 3h; Irradiation; Inert atmosphere;

: 74-90-8
hydrogen cyanide

: 151-50-8
potassium cyanide

: 75-07-0
acetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
at 25 - 30℃;

...Expand

: 74-90-8
hydrogen cyanide

: 75-07-0
acetaldehyde

A: 107-13-1
acrylonitrile

B: 78-97-7
2-hydroxy-propionitrile

...Expand

: 74-90-8
hydrogen cyanide

: 67-66-3
chloroform

: 75-07-0
acetaldehyde

: 130-95-0
Quinine

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
at 25℃;

...Expand

: 143-33-9
sodium cyanide

: 75-07-0
acetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With ammonium chloride In diethyl ether
With Dowex-H+ In water for 24h; Ambient temperature;

: 17374-27-5
1,5-dimethylimidazolidine-2,4-dione

A: 16752-54-8
methylaminopropionitrile

B: 57768-53-3
α-methylaminodipropionitrile

C: carbamate de l' α-N-methylaminopropionitrile

D: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 30℃; Equilibrium constant; K as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 16752-54-8
methylaminopropionitrile

A: 17374-27-5
1,5-dimethylimidazolidine-2,4-dione

B: 57768-53-3
α-methylaminodipropionitrile

C: carbamate de l' α-N-methylaminopropionitrile

D: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With sodium carbonate at 50℃; Product distribution;
With sodium hydrogencarbonate at 30℃; Rate constant; Equilibrium constant; k as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 72-19-5
L-threonine

: 127-65-1
chloroamine-T

A: 70-55-3
toluene-4-sulfonamide

B: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With hydrogenchloride; sodium chloride In water at 29.9 - 44.9℃; for 24h; Kinetics; Mechanism; Thermodynamic data; effect of +>, ->, and ; with HClO4 and H2SO4 also; solvent isotope effect; variation of ionic strength and addition of the product, p-toluenesulfonamide; decrease of dielectric constant by methanol; ΔH(excit.), ΔS(excit.), ΔG(excit.);

...Expand

: 72-19-5
L-threonine

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With perchloric acid; N-chlorobenzotriazole; chloride In water at 29.9℃; Kinetics; Mechanism;

: 15657-96-2
1-cyanoethyl acetate

A: 78-97-7
2-hydroxy-propionitrile

B: (S)-O-acetyl-1-cyanoethanol

Conditions

Conditions	Yield
With Candida tropicalis at 30℃; for 96h; Quantum yield; Hydrolitic efficiency of other microorganisms; Penicillium notatum, Aspergillus flavas, Pseudomonas fluorescens;

: 2869-25-2
2,2'-iminodipropionitrile

A: carbamate de l' α-aminopropionitrile

B: 78-97-7
2-hydroxy-propionitrile

C: 51806-98-5, 95596-57-9, 2134-48-7
2-aminopropanenitrile

D: 67337-69-3
methyl-5 hydantoine

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 30℃; Equilibrium constant; K as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 72-19-5
L-threonine

A: 124-38-9
carbon dioxide

B: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With hydrogenchloride; chloroamine-T In water at 29.9 - 44.9℃; Thermodynamic data; Rate constant; Ea, log A, -ΔS(excit.), ΔH(excit.), ΔG(excit.); further acid concentration, further acid and alkaline media;

: 57768-53-3
α-methylaminodipropionitrile

A: 17374-27-5
1,5-dimethylimidazolidine-2,4-dione

B: 16752-54-8
methylaminopropionitrile

C: carbamate de l' α-N-methylaminopropionitrile

D: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 30℃; Equilibrium constant; K as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 151-50-8
potassium cyanide

: 918-04-7
potassium 1-hydroxyethane-1-sulfonate

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
In water

: carbamate de l' α-aminopropionitrile

A: 2869-25-2
2,2'-iminodipropionitrile

B: 78-97-7
2-hydroxy-propionitrile

C: 51806-98-5, 95596-57-9, 2134-48-7
2-aminopropanenitrile

D: 67337-69-3
methyl-5 hydantoine

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 30℃; Equilibrium constant; K as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: carbamate de l' α-N-methylaminopropionitrile

A: 17374-27-5
1,5-dimethylimidazolidine-2,4-dione

B: 16752-54-8
methylaminopropionitrile

C: 57768-53-3
α-methylaminodipropionitrile

D: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 30℃; Equilibrium constant; K as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 497-19-8
sodium carbonate

: 51806-98-5, 95596-57-9, 2134-48-7
2-aminopropanenitrile

A: 2869-25-2
2,2'-iminodipropionitrile

B: 4744-01-8
α-carboxyaminopropionamide

C: α-carboxyaminopropionitrile

D: 78-97-7
2-hydroxy-propionitrile

E: 67337-69-3
methyl-5 hydantoine

F: 4726-84-5
alanine amide

Conditions

Conditions	Yield
With ammonia In water at 50℃; Product distribution; Kinetics; pH=8.9 and 9.5;

...Expand

: 51806-98-5, 95596-57-9, 2134-48-7
2-aminopropanenitrile

A: 2869-25-2
2,2'-iminodipropionitrile

B: carbamate de l' α-aminopropionitrile

C: 78-97-7
2-hydroxy-propionitrile

D: 67337-69-3
methyl-5 hydantoine

Conditions

Conditions	Yield
With sodium carbonate at 50℃; Product distribution;
With sodium hydrogencarbonate at 30℃; Rate constant; Equilibrium constant; k as a function of pH and concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 67337-69-3
methyl-5 hydantoine

A: 2869-25-2
2,2'-iminodipropionitrile

B: carbamate de l' α-aminopropionitrile

C: 78-97-7
2-hydroxy-propionitrile

D: 51806-98-5, 95596-57-9, 2134-48-7
2-aminopropanenitrile

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 30℃; Equilibrium constant; K as a function of pH and the concentration of carbonate, borate, phosphate and ammonia;

...Expand

: 72-19-5, 80-68-2, 144-98-9, 632-20-2, 2676-21-3, 7004-04-8, 24830-94-2, 28954-12-3, 36676-50-3
DL-threonine

A: 124-38-9
carbon dioxide

B: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With perchloric acid; sodium bismuthate; hydrogen fluoride In water at 35℃; for 3h; Kinetics; Further Variations:; Temperatures; Oxidation;

: 74-90-8
hydrogen cyanide

2cetaldehyde: 2cetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
With pyridine; acetic acid; 2-hydroxy-propionitrile

: 74-90-8
hydrogen cyanide

: 7732-18-5
water

: 75-07-0
acetaldehyde

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
at 25 - 60℃; Rate constant;
at 25 - 60℃; Equilibrium constant;

...Expand

: 74-90-8
hydrogen cyanide

: 75-07-0
acetaldehyde

K2CO3: K2CO3

: 78-97-7
2-hydroxy-propionitrile

Conditions

Conditions	Yield
at 25 - 30℃;

...Expand

: 631-57-2
Acetyl cyanide

hydrogen: hydrogen

A: 78-97-7
2-hydroxy-propionitrile

B: 107-12-0
propiononitrile

Conditions

Conditions	Yield
at 200 - 225℃; Nickel-Kieselgur-Katalysator;

...Expand

: 72-19-5
L-threonine

A: 78-97-7
2-hydroxy-propionitrile

B CO2: CO2

Conditions

Conditions	Yield
With formaldehyd; perchloric acid; bromamine T In water at 29.9℃; Kinetics; Mechanism; Thermodynamic data; E(activ.), ΔG(excit.), ΔH(excit.), ΔS(excit.); other temperatures and solvent, effect of acid concentration, no influence of ionic strength and tosylamine addition;

: 78-97-7
2-hydroxy-propionitrile

: 2-Hydroxy-propionimidic acid ethyl ester hydrochloride

Conditions

Conditions	Yield
In diethyl ether; ethanol	99%
In diethyl ether; ethanol	815 g (99%)

: 78-97-7
2-hydroxy-propionitrile

: 98-59-9
p-toluenesulfonyl chloride

: 33695-65-7
1-cyanoethyl p-toluenesulfonate

Conditions

Conditions	Yield
With sodium hydroxide In 1,4-dioxane; toluene at 0 - 25℃;	98.34%

: 78-97-7
2-hydroxy-propionitrile

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 1-cyanoethyl p-nitrobenzenesulfonate

Conditions

Conditions	Yield
With sodium hydroxide at 0 - 10℃;	98.34%

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 78-97-7
2-hydroxy-propionitrile

: 33695-77-1
p-chlorobenzenesulfonic acid 1-cyanoethyl ester

Conditions

Conditions	Yield
With sodium carbonate at 0 - 25℃;	97.52%

: 124-63-0
methanesulfonyl chloride

: 78-97-7
2-hydroxy-propionitrile

: 6839-20-9
2-[(methylsulfonyl)oxy]propanenitrile

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 25℃; for 24h;	96.78%
With triethylamine In dichloromethane at 0℃; for 0.5h; Mesylation;	91%

: 78-97-7
2-hydroxy-propionitrile

: 594-44-5
Ethanesulfonyl chloride

: 2-[(ethylsulfonyl)oxy]propanenitrile

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In toluene at 0 - 10℃; for 24h;	96.01%
With triethylamine In dichloromethane at 0 - 20℃; for 3.5h; Substitution;	88%

: 78-97-7
2-hydroxy-propionitrile

: 598-81-2, 2043-43-8, 65144-02-7, 89673-71-2
(+/-)-lactamide

Conditions

Conditions	Yield
Stage #1: 2-hydroxy-propionitrile With Caproamide; acetic acid at 50℃; for 0.5h; Schlenk technique; Inert atmosphere; Stage #2: With palladium (II) nitrate at 50℃; for 0.166667h; Schlenk technique; Inert atmosphere;	96%
With CF3O3S(1-)*C36H35ClFeOP3Pt(1+); water; silver trifluoromethanesulfonate In tetrahydrofuran at 40℃; for 12h; Catalytic behavior; Inert atmosphere;	93%
With [RuCl2(η3:η3-C10H16){PMe2(OH)}]; water at 20℃; for 72h; Inert atmosphere; Schlenk technique; Sealed tube;	85%

: 98-88-4
benzoyl chloride

: 78-97-7
2-hydroxy-propionitrile

: 98777-16-3
2-benzoyloxy-1-butyronitrile

Conditions

Conditions	Yield
In pyridine at 20℃; for 2h;	96%
With triethylamine In dichloromethane at 0 - 20℃;	85%

: 78-97-7
2-hydroxy-propionitrile

: 2-hydroxypropanethioamide

Conditions

Conditions	Yield
With hydrogenchloride; thiophosphate sodium salt hydrate In water; water-d2 at 50℃; for 24h; pH=6.5; Sealed tube;	96%

: 78-97-7
2-hydroxy-propionitrile

: 98-09-9
benzenesulfonyl chloride

: 10531-15-4
1-cyanoethyl benzenesulfonate

Conditions

Conditions	Yield
With pyridine In tetrahydrofuran at 0 - 20℃; for 24h;	95.2%

: 421-83-0
trifluoromethane sulfonyl chloride

: 78-97-7
2-hydroxy-propionitrile

: 1403873-31-3
1-cyanoethyl trifluoromethanesulfonate

Conditions

Conditions	Yield
With potassium carbonate at 0 - 25℃; for 20h;	94.13%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 78-97-7
2-hydroxy-propionitrile

: 114711-04-5
2-[(tert-butyldimethylsilyl)oxy]propanenitrile

Conditions

Conditions	Yield
With triethylamine; 2,8,9-Trimethyl-2,5,8,9-tetraaza-1-phospha-bicyclo[3.3.3]undecane 1-oxide In [D3]acetonitrile at 25℃; for 6h;	94%
With P(MeNCH2CH2)3N; triethylamine In acetonitrile at 24℃; for 0.2h;	90%
With 1H-imidazole In N,N-dimethyl-formamide Ambient temperature;	70%

: 78-97-7
2-hydroxy-propionitrile

: 586-75-4
4-chlorobenzoyl chloride

: 1569086-99-2
1-cyanoethyl 4-bromobenzoate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	94%

ClNH4: ClNH4

: 78-97-7
2-hydroxy-propionitrile

: 4726-84-5
alanine amide

Conditions

Conditions	Yield
With sodium hydroxide In ammonium hydroxide; acetone	92%

: 13162-05-5
n-vinylformamide

: 78-97-7
2-hydroxy-propionitrile

: N-[α-(α'-cyanoethoxy)ethyl]formamide

Conditions

Conditions	Yield
With boron trifluoride at 0℃; for 18h; Addition;	91%

: 79-37-8
oxalyl dichloride

: 78-97-7
2-hydroxy-propionitrile

: 125849-94-7
3,5-dichloro-6-methyl-2(H)-1,4-oxazin-2-one

Conditions

Conditions	Yield
With triethylamine hydrochloride In chlorobenzene at 90℃; for 3h;	90%
With triethylamine hydrochloride In chlorobenzene at 90℃; for 3h; Inert atmosphere;	90%
Stage #1: oxalyl dichloride; 2-hydroxy-propionitrile In chlorobenzene at 0℃; Stage #2: With triethylamine hydrochloride In chlorobenzene at 0 - 90℃; Inert atmosphere;	81%

: 64-17-5
ethanol

: 78-97-7
2-hydroxy-propionitrile

: 2-Hydroxy-propionimidic acid ethyl ester hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether at -5 - 26℃; for 18h;	90%
With hydrogenchloride In diethyl ether at 0 - 5℃; for 48h;

: 104-94-9
4-methoxy-aniline

: 78-97-7
2-hydroxy-propionitrile

: 2-((4-methoxyphenyl)amino)propanenitrile

Conditions

Conditions	Yield
In ethanol for 18h; Reflux;	90%
With titanium(IV) isopropylate In toluene at 40℃; for 18h; Inert atmosphere; Glovebox;	56%

: 109-92-2
ethyl vinyl ether

: 78-97-7
2-hydroxy-propionitrile

: 53411-95-3
2-<(1'-ethoxy)ethoxy> propionitrile

Conditions

Conditions	Yield
With hydrogenchloride at 80℃; for 3h;	88%
With acid

: 78-97-7
2-hydroxy-propionitrile

: 52046-55-6
2,N-dihydroxy-propionamidine

Conditions

Conditions	Yield
With sodium hydroxide; hydroxylamine hydrochloride In ethanol at 20℃;	87%
With hydroxylamine hydrochloride; sodium ethanolate
With hydroxylamine hydrochloride; water; sodium carbonate

: 67-56-1
methanol

: 78-97-7
2-hydroxy-propionitrile

: 547-64-8
methyl lactate

Conditions

Conditions	Yield
With hydrogenchloride; water at -10 - -5℃; for 4h; Reflux;	85.58%

: 358-23-6
trifluoromethylsulfonic anhydride

: 78-97-7
2-hydroxy-propionitrile

: 1403873-31-3
1-cyanoethyl trifluoromethanesulfonate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0℃; for 0.25h; Inert atmosphere;	82%

: 506-87-6
ammonium carbonate

: 78-97-7
2-hydroxy-propionitrile

A: 39121-77-2
α-ureido-propionamide

B: 67337-69-3
methyl-5 hydantoine

Conditions

Conditions	Yield
In water at 50℃; for 4h; pH=7.9;	A 20% B 80%

...Expand

: 78-97-7
2-hydroxy-propionitrile

: 100-58-3
phenylmagnesium bromide

: 5650-40-8
2-hydroxypropiophenone

Conditions

Conditions	Yield
In diethyl ether for 0.25h; Heating;	80%

: 1603-41-4
(5-methyl-pyridin-2-yl)amine

: 78-97-7
2-hydroxy-propionitrile

: 1176904-05-4
2-[(2,6-dimethylimidazo[1,2-a]pyridine-3-yl)amino]propanenitrile

Conditions

Conditions	Yield
Stage #1: (5-methyl-pyridin-2-yl)amine; 2-hydroxy-propionitrile With silica-gel-supported sulfuric acid at 20℃; Stage #2: With ammonia In water	80%

: 78-97-7
2-hydroxy-propionitrile

: 105-53-3
diethyl malonate

: 139003-80-8
ethyl 4-amino-2,5-dihydro-5-methyl-2-oxo-3-furancarboxylate

Conditions

Conditions	Yield
With tin(IV) chloride In ethyl acetate for 48h; Ambient temperature;	79%

Lactonitrile Chemical Properties

IUPAC Name: 2-Hydroxypropanenitrile
CAS: 78-97-7
EINECS: 201-163-2
Following is the Molecular Structure of Lactonitrile (78-97-7):

SMILES: N#CC(C)O
Molecular Formula: C₃H₅NO
Molecular Weight: 71.08
Melting Point:<21℃
Boiling Point: 183.4℃ at 760mmHg
Flash Point: 64.7℃
Molar Volume: 69.3cm³
Density: 1.025g/cm³
Molar Refractivity: 17.35cm³
Surface Tension: 39.6dyne/cm
Polarizability: 6.87 10^-24cm³
Enthalpy of Vaporization: 48.84kJ/mol
Vapour Pressure: 0.222mmHg at 25℃
Refractive Index: n20/D 1.404

Lactonitrile Uses

Solvent, intermediate in production of Ethyl acetate and Lactic acid .

Lactonitrile Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	subcutaneous	300mg/kg (300mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
mouse	LD50	intraperitoneal	15mg/kg (15mg/kg)	BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 84, Pg. 533, 1986.
rabbit	LD50	skin	20uL/kg (0.02mL/kg)		American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rabbit	LDLo	subcutaneous	5200ug/kg (5.2mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
rat	LCLo	inhalation	125ppm/4H (125ppm)		American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat	LD50	oral	87mg/kg (87mg/kg)		American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.

Lactonitrile Consensus Reports

EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory. Cyanide and its compounds are on the Community Right-To-Know List.

Lactonitrile Safety Profile

Hazard Codes: T+ Very toxic, T Toxic.
Risk Statements: 23/25-27-25-20
R23/25: Toxic by inhalation and if swallowed.
R27: Very Toxic in contact with skin.
R25: Toxic if swallowed.
R20: Harmful by inhalation.
Safety Statements: 13-36/37/39-45-23
S13: Keep away from food, drink and animal feeding stuffs.
S36/27/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
S23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer).
RIDADR: UN 3276 6.1/PG 1
WGK: Germany 3
RTECS: OD8225000
HazardClass: 6.1(a)
PackingGroup: II
Poison by ingestion, skin contact, and subcutaneous routes. Moderately toxic by inhalation. In the presence of alkali, it evolves HCN .Combustible when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use foam, CO₂, dry chemical.

Lactonitrile Specification

Lactonitrile (78-97-7),which also can be called for 2-Hydroxypropanenitrile ; 2-Hydroxypropannitril ; 2-Hydroxypropannitril ; 2-Hydroxypropionitrile ; Acetaldehyde ; Cyanohydrin ; Acetocyanohydrin ; Ethylidene cyanohydrin ; Lactonitrile ; Laktonitril ; Laktonitril ; Propanenitrile,2-hydroxy- ; Propionitrile,2-hydroxy- ; Alpha-hydroxypropionitrile . Lactonitrile (78-97-7) is a straw colored liquid and it's very soluble in water.When heated to decomposition it emits toxic fumes of CN− and NOx .This chemical should be stored in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Product Name

Lactonitrile

Synthetic route

Lactonitrile Chemical Properties

Lactonitrile Uses

Lactonitrile Toxicity Data With Reference

Lactonitrile Consensus Reports

Lactonitrile Safety Profile

Lactonitrile Specification

Related Products

Hot Products