Lactose supplier | CasNO.63-42-3

Name
Lactose
EINECS 200-559-2
CAS No. 63-42-3
Density 1.76 g/cm³
Solubility 5-10 g/100 mL at 20 °C in water
Melting Point 222.8 °C
Formula C₁₂H₂₂O₁₁
Boiling Point 667.9 °C at 760 mmHg
Molecular Weight 342.3
Flash Point 357.8 °C
Transport Information
Appearance white crystals or powder
Safety 24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 4-O-beta-D-Galactopyranosyl-D-glucose;D-Glucose, 4-O-beta-D-galactopyranosyl-;Galactinum;Fast-flo Lactose;
PSA 197.37000
LogP -5.55460

Synthetic route

: 492-61-5
β-D-glucose

: 5435-44-9, 22243-66-9
(E)-3-Ureido-but-2-enoic acid ethyl ester

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
at 175℃; under 15 Torr;

: 64-19-7
acetic acid

: 41263-94-9
2’-fucosyllactose

A: 2438-80-4
L-Fucose

B: 63-42-3
D-(+)-lactose

...Expand

: 3616-19-1, 5328-50-7, 5346-90-7, 6291-42-5, 6920-00-9, 20764-63-0, 20880-60-8, 20880-65-3, 22352-19-8, 23973-20-8, 32447-69-1, 34213-32-6, 52554-32-2, 53956-64-2, 56907-29-0, 56994-12-8, 56994-13-9, 57128-38-8, 67650-36-6, 68036-17-9, 68036-19-1, 78215-50-6, 78215-51-7, 79549-48-7, 80446-82-8, 85249-04-3, 93221-83-1, 93779-27-2, 111407-83-1, 111407-84-2, 111407-85-3, 120328-65-6, 123809-59-6, 132341-46-9, 132341-47-0, 132341-49-2, 145307-94-4
1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
With methanol; barium methoxide

: 492-61-5
β-D-glucose

β-D-galactose: β-D-galactose

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
With zinc(II) chloride at 175℃; under 15 Torr;

: 3068-32-4
1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

O2,O3;O5,O6-diisopropylidene-D-glucose-diethylacetal: O2,O3;O5,O6-diisopropylidene-D-glucose-diethylacetal

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
With chloroform; iodine; silver(l) oxide anschl. mit methanol. NaOH und dann mit wss. Essigsaeure;

: 7647-01-0
hydrogenchloride

: 41263-94-9
2’-fucosyllactose

A: 2438-80-4
L-Fucose

B: 63-42-3
D-(+)-lactose

...Expand

: 909878-64-4
meso-erythritol

: 87-69-4
L-Tartaric acid

A: 488-73-3
(+)-proto-quercitol

B: 57-50-1
Sucrose

C: 63-42-3
D-(+)-lactose

D pinitol: pinitol

...Expand

: 63-42-3
D-(+)-lactose

: 96-82-2, 534-41-8, 534-42-9, 51267-45-9, 58459-39-5, 69728-97-8
lactobionic acid

Conditions

Conditions	Yield
With oxygen for 2h; Reagent/catalyst;	100%
With sodium hydroxide; palladium dichloride; potassium hexacyanoferrate(III) In water at 35℃; Rate constant; Thermodynamic data; Eact, ΔS(excit.), ΔH(excit.), ΔG(excit.);
With sodium hydroxide; potassium hexacyanoferrate(III) In water at 35℃; Rate constant; Thermodynamic data; Eact, ΔS(excit.), ΔH(excit.), ΔG(excit.);

: 2016-42-4
tetradecylamine

: 63-42-3
D-(+)-lactose

: N-tetradecyl lactosamine

Conditions

Conditions	Yield
at -10℃;	92%

: 124-22-1
n-Dodecylamine

: 63-42-3
D-(+)-lactose

: N-dodecyl lactosamine

Conditions

Conditions	Yield
at -10℃;	90%

: 929-59-9
3,6-dioxa-1,8-diaminooctane

: 63-42-3
D-(+)-lactose

: 1,8-bis(1-deoxy-D-lactitol-1-ylamino)-3,6-dioxaoctane

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol; water at 40℃; under 6750.68 Torr; for 24h;	87%

: 1111-78-0
ammonium carbamate

: 63-42-3
D-(+)-lactose

: (2S,3R,4S,5R,6R)-2-((2R,3S,4R,5R,6R)-6-Amino-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol; compound with carbamic acid

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 20h;	85%

: carbonic acid bis(1-isopropylhydrazide) dihydrochloride

: 63-42-3
D-(+)-lactose

: 1'S,2'R,3'R,4'R-2,4-diisopropyl-6-(3'-α-D-galactopyranosyl-1',2',4',5'-tetrahydroxypentyl)-1,2,4,5-tetrazinan-3-one

Conditions

Conditions	Yield
With sodium acetate In water at 20℃;	83%

: 760-30-5
2-mercaptoacetohydrazide

: 63-42-3
D-(+)-lactose

: D-lactose (2-sulfanylacetyl)hydrazone

Conditions

Conditions	Yield
In water at 25℃; for 72h;	70%

: 75-36-5
acetyl chloride

: 63-42-3
D-(+)-lactose

: 14227-58-8
2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-glucopyranosyl chloride

Conditions

Conditions	Yield
With indium(III) triflate at 20℃; for 5h;	65%

: 24611-43-6
2-mercaptobenzoic acid hydrazide

: 63-42-3
D-(+)-lactose

: D-lactose (2-sulfanylbenzoyl)hydrazone

Conditions

Conditions	Yield
In water at 25℃; for 72h;	65%

: 63-42-3
D-(+)-lactose

: C12H14O28S6(6-)*6Na(1+)

Conditions

Conditions	Yield
Stage #1: D-(+)-lactose With triethylamine sulfur trioxide In N,N-dimethyl-formamide at 120℃; for 0.166667h; Inert atmosphere; Stage #2: In water	64%

: calcium 3-{[(2S,4R)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoate

: 63-42-3
D-(+)-lactose

: C24H28NO5(1-)*Na(1+)*C12H22O11

Conditions

Conditions	Yield
Stage #1: calcium 3-{[(2S,4R)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoate With hydrogenchloride In water; acetonitrile at 25℃; Stage #2: With sodium 2-ethylhexanoic acid In acetonitrile at 40℃; for 12h; Stage #3: D-(+)-lactose In acetonitrile at 0℃; for 2h;	59.6%

: 2146-71-6
vinyl laurate

: 63-42-3
D-(+)-lactose

A: 143-07-7
lauric acid

B: lactose (C-6')-monolaurate

Conditions

Conditions	Yield
Lipozyme, immobilized from Mucor miehei (MM) In tert-Amyl alcohol at 55℃; for 72h; Product distribution / selectivity; Molecular sieve; Enzymatic reaction;	A n/a B 52.4%

...Expand

: 7493-95-0
4-nitrophenyl α-D-galactoside

: 63-42-3
D-(+)-lactose

: α-D-galactopyranosyl(1->6)-β-D-galactopyranosyl-(1->4)-D-glucopyranose

Conditions

Conditions	Yield
With recombinant Aspergillus nidulans FGSC GH36 α-galactosidase at 37℃; for 3h; pH=5; aq. acetate buffer; Enzymatic reaction; regioselective reaction;	38%

: 204255-11-8
oseltamivir phosphate

: 63-42-3
D-(+)-lactose

: 1296084-57-5
(3R,4R,5S)-ethyl 4-acetamido-N-(1'-deoxylactitol-1'-yl)-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate

Conditions

Conditions	Yield
Stage #1: oseltamivir phosphate; D-(+)-lactose at 20℃; for 1h; pH=7.4; aq. phosphate buffer; Stage #2: With sodium cyanoborohydride at 80℃; for 6h; aq. phosphate buffer;	36%

: 124-09-4
1,6-Hexanediamine

: 63-42-3
D-(+)-lactose

: 1,6-bis(1-deoxy-D-lactitol-1-ylamino)hexane

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol; water at 40℃; under 6750.68 Torr; for 24h;	35%

: 107-19-7
propargyl alcohol

: 63-42-3
D-(+)-lactose

: 151168-59-1
1-propynyl-β-D-galactopyranoside

Conditions

Conditions	Yield
With Aspergillus oryzae β-galactosidase at 25℃; pH=4.5; aq. acetate buffer; Enzymatic reaction;	26%

: 110-65-6
1,4-dihydroxybut-2-yne

: 63-42-3
D-(+)-lactose

: 1190202-83-5
4-hydroxybut-2-yn-1-yl β-D-galactopyranoside

Conditions

Conditions	Yield
With Aspergillus oryzae β-galactosidase at 25℃; pH=4.5; aq. acetate buffer; Enzymatic reaction;	21%

: 98-88-4
benzoyl chloride

: 63-42-3
D-(+)-lactose

: 41093-35-0
2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1→4)-1,2,6-tri-O-benzoyl-β-D-glucopyranose

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 1h;	20%

: 927-74-2
1-butyn-4-ol

: 63-42-3
D-(+)-lactose

: 1190202-80-2
1-O-but-3-ynyl-α-D-galactopyranoside

Conditions

Conditions	Yield
With Aspergillus oryzae β-galactosidase at 25℃; pH=4.5; aq. acetate buffer; Enzymatic reaction;	18%

: 5390-04-5
pent-1-yn-5-ol

: 63-42-3
D-(+)-lactose

: 1190202-81-3
pent-4-yn-1-yl β-D-galactopyranoside

Conditions

Conditions	Yield
With Aspergillus oryzae β-galactosidase at 25℃; pH=4.5; aq. acetate buffer; Enzymatic reaction;	17%

: 764-60-3
hex-2-yn-1-ol

: 63-42-3
D-(+)-lactose

: 1190202-86-8
hex-2-yn-1-yl β-D-galactopyranoside

Conditions

Conditions	Yield
With Aspergillus oryzae β-galactosidase at 25℃; pH=4.5; aq. acetate buffer; Enzymatic reaction;	16%

Lactose Chemical Properties

Molecular Structure:

Molecular Formula: C₁₂H₂₂O₁₁
Molecular Weight: 342.30
IUPAC Name: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Synonyms of Lactose (CAS NO.200-559-2): (+)-Lactose ; 4-(beta-D-Galactosido)-D-glucose ; 4 -O-beta-D-Galactopyranosyl-D-glucose ; D-Lactose ; Lactose, anhydrous
CAS NO: 200-559-2
EINECS: 200-559-2
H bond acceptors: 11
H bond donors: 8
Freely Rotating Bonds: 12
Polar Surface Area: 101.53 Å²
Index of Refraction: 1.652
Molar Refractivity: 70.8 cm³
Molar Volume: 193.6 cm³
Surface Tension: 110.8 dyne/cm
Density: 1.76 g/cm³
Flash Point: 357.8 °C
Enthalpy of Vaporization: 112.36 kJ/mol
Boiling Point: 667.9 °C at 760 mmHg
Vapour Pressure: 1.08E-20 mmHg at 25°C
Melting Point: 222.8°C
Water Solubility: 5-10 g/100 mL at 20 ºC
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance: white crystals or powder
Product Categories of Lactose (CAS NO.200-559-2): Dextrins、Sugar & Carbohydrates

Lactose Uses

Lactose (CAS NO.200-559-2) is used in stout beers rarely to sweeten the beer and is non-fermentable in beer.

Lactose Production

Lactose (CAS NO.200-559-2) is little fermented by baker's yeast and during brewing, which may be used to advantage. It is extracted from sweet or sour whey.

Lactose Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
dog	LDLo	intravenous	1500mg/kg (1500mg/kg)	"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

Lactose Consensus Reports

Reported in EPA TSCA Inventory.

Lactose Safety Profile

WGK Germany: 2
RTECS: OD9625000
Moderately toxic by intravenous route. Questionable carcinogen with experimental tumorigenic and teratogenic data. Mixtures with oxidants (e.g., potassium chlorate, potassium nitrate, or potassium perchlorate) may be explosion hazards. When heated to decomposition it emits acrid smoke and irritating fumes.

Lactose Specification

Lactose is a sugar that is found most notably in milk. The name comes from the Latin word for milk, plus the -ose ending used to name sugars.

Product Name

Lactose

Synthetic route

Lactose Chemical Properties

Lactose Uses

Lactose Production

Lactose Toxicity Data With Reference

Lactose Consensus Reports

Lactose Safety Profile

Lactose Specification

Related Products

Hot Products