Product Name

  • Name

    Lauric acid

  • EINECS 205-582-1
  • CAS No. 143-07-7
  • Article Data325
  • CAS DataBase
  • Density 0.905 g/cm3
  • Solubility insoluble in water
  • Melting Point 44-46 °C
  • Formula C12H24O2
  • Boiling Point 296.1 °C at 760 mmHg
  • Molecular Weight 200.321
  • Flash Point 134.1 °C
  • Transport Information
  • Appearance white solid
  • Safety 37/39-26
  • Risk Codes 36/38
  • Molecular Structure Molecular Structure of 143-07-7 (Lauric acid)
  • Hazard Symbols IrritantXi
  • Synonyms ABL;Dodecylic acid;Vulvic acid;Hydrofol acid 1295;1-Undecanecarboxylic acid;2661G Undecane,1-phenyl1-Undecanecarboxylic acid;Lunac L 70;Coconut oil fatty acids;Ninol AA62 extra;Prifac 2920;Hydrofol acid 1255;NAA 312;Dodecanoic acid, potassium salt;Univol U-314;
  • PSA 37.30000
  • LogP 3.99190

Synthetic route

1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With air; sodium nitrite In trifluoroacetic acid at 0 - 20℃; for 5h;100%
With Iron(III) nitrate nonahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium chloride; oxygen In 1,2-dichloro-ethane at 25℃; for 12h;100%
With Iron(III) nitrate nonahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium chloride; oxygen In 1,2-dichloro-ethane at 20℃; for 12h; Reagent/catalyst; Schlenk technique;100%
S-tert-butyl dodecanethioate
107154-75-6

S-tert-butyl dodecanethioate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With water; hydrophobic polystyrene-supported sulfonic acid for 168h; Heating;100%
3-oxo-2-phenylsulfanyltetradecanamide
1321499-06-2

3-oxo-2-phenylsulfanyltetradecanamide

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With sodium hydrogencarbonate; 2-oxopropanal In methanol; water at 20℃; for 1h; Inert atmosphere;100%
benzyl dodecanoate
140-25-0

benzyl dodecanoate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With aluminum tri-bromide; ethanethiol for 0.5h; Ambient temperature;99.2%
With magnesium iodide In toluene for 48h; Heating;70%
Dodecanal
112-54-9

Dodecanal

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With iron oxide; oxygen; ethyl acetoacetate at 75 - 80℃; under 760.051 Torr; for 24h; Green chemistry;99%
With oxygen; copper(II) acetate monohydrate; cobalt(II) diacetate tetrahydrate In water at 40℃; under 760.051 Torr; for 3h;97%
With Iron(III) nitrate nonahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium chloride; oxygen In 1,2-dichloro-ethane at 25℃; for 12h;94%
1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

A

lauric acid
143-07-7

lauric acid

B

Conditions
ConditionsYield
With sodium hypochlorite; sodium hydrogencarbonate; potassium bromide; [4-(TEMPO-4-yloxymethyl)-1H-[1,2,3]triazol-1-ylmethyl]-PS In dichloromethane at 0℃; for 0.5h;A n/a
B 99%
With C30H24N2O7W; dihydrogen peroxide In water; acetonitrile for 22h; Reflux;A 1%
B 82%
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; oxone; potassium bromide; methyltrioxorhenium(VII) In acetonitrile at 0℃; for 4h;A 6%
B 53%

A

B

C16H10O3S

C16H10O3S

Conditions
ConditionsYield
In d(4)-methanol at 20℃; Conversion of starting material; light irradiation;A 99%
B n/a
bromobutyric acid

bromobutyric acid

n-octylmagnesium chloride

n-octylmagnesium chloride

lauric acid

lauric acid

Conditions
ConditionsYield
Stage #1: bromobutyric acid With 1-methyl-pyrrolidin-2-one; tert-butylmagnesium chloride In tetrahydrofuran at -78℃; for 0.166667h; Inert atmosphere;
Stage #2: n-octylmagnesium chloride With buta-1,3-diene; nickel dichloride In tetrahydrofuran under 760.051 Torr; for 1h; Inert atmosphere; Cooling with ice;
99%
methyl n-dodecanoate
111-82-0

methyl n-dodecanoate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With aluminum tri-bromide; ethanethiol for 48h; Ambient temperature;98.7%
With AlBrCl3(1-)*C5H5N*H(1+) at 140℃; for 3h;98%
With iodine; aluminium In acetonitrile at 80℃; for 18h;97%
S-phenyl dodecanethioate
79817-20-2

S-phenyl dodecanethioate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With water; hydrophobic polystyrene-supported sulfonic acid for 24h; Heating;98%
tridodecanoylglycerol
538-24-9

tridodecanoylglycerol

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 1h; Reflux;98%
With aquivion perfluorosulfonic superacid loaded on H+ In neat (no solvent) at 100℃; under 760.051 Torr; for 8h; Reagent/catalyst;
ethyl laurate
106-33-2

ethyl laurate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With AlBrCl3(1-)*C5H5N*H(1+) at 140℃; for 3h;97%
With 2C33H37N*H2O7S2; water at 60℃; for 20h;83%
With aluminum tri-bromide; ethanethiol for 792h; Ambient temperature;73.5%
With 2C33H37N*H2O7S2; water at 80℃;83 %Spectr.
With Novozym 435 from Candida antarctica at 0 - 40℃; for 32h;
Dodecanoic acid 3-methyl-but-2-enyl ester

Dodecanoic acid 3-methyl-but-2-enyl ester

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With iodine In cyclohexane for 6h; Ambient temperature;97%
S-dodecyl dodecanethioate
103212-64-2

S-dodecyl dodecanethioate

A

lauric acid
143-07-7

lauric acid

B

1-dodecylthiol
112-55-0

1-dodecylthiol

Conditions
ConditionsYield
With C18-alkylated polystyrene-supported sulfonic acid; water for 24h; Heating;A 96%
B n/a
With water; hydrophobic polystyrene-supported sulfonic acid for 72h; Heating;A 95%
B 95%
With C18-alkylated polystyrene-supported sulfonic acid; water for 24h; Heating;
S-dodecyl dodecanethioate
103212-64-2

S-dodecyl dodecanethioate

A

lauric acid
143-07-7

lauric acid

B

didodecyl sulfide
2469-45-6

didodecyl sulfide

C

1-dodecylthiol
112-55-0

1-dodecylthiol

Conditions
ConditionsYield
With water; hydrophobic polystyrene-supported sulfonic acid for 72h; Heating;A 95%
B 2%
C n/a

lauric acid

lauric acid

Conditions
ConditionsYield
With tert.-butylnitrite; water at 29℃; for 0.583333h;95%

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; W(OTf)6; hydrogen at 135℃; under 760.051 Torr; for 12h;94%
With palladium on activated carbon; W(OTf)6; hydrogen In neat (no solvent) at 135℃; under 760.051 Torr; for 12h;94%

Conditions
ConditionsYield
With water; hydrophobic polystyrene-supported sulfonic acid for 36h; Heating;93%

A

lauric acid
143-07-7

lauric acid

B

ethyl laurate
106-33-2

ethyl laurate

Conditions
ConditionsYield
With hydrogen In ethanol; water at 240℃; under 25066.7 Torr; for 144h;A 6%
B 93%
2-chloroethyl dodecanoate
64919-15-9

2-chloroethyl dodecanoate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With sodium tetrahydroborate; selenium In N,N-dimethyl-formamide for 3h; Ambient temperature; also with NaHTe as cat.;92%
2,2,2-Trichloroethyl dodecanoate
71071-51-7

2,2,2-Trichloroethyl dodecanoate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With sodium tetrahydroborate; selenium In N,N-dimethyl-formamide at 40 - 50℃; for 1h;92%
2-dodecanoyloxyethyl dodecanoate
624-04-4

2-dodecanoyloxyethyl dodecanoate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With 2C33H37N*H2O7S2; water at 60℃; for 24h;92%
With 2C33H37N*H2O7S2; water at 80℃;92 %Spectr.
benzyl dodecanoate
140-25-0

benzyl dodecanoate

toluene
108-88-3

toluene

A

lauric acid
143-07-7

lauric acid

B

1-methyl-3-(phenylmethyl)-benzene
620-47-3

1-methyl-3-(phenylmethyl)-benzene

C

1-methyl-4-(phenylmethyl)benzene
620-83-7

1-methyl-4-(phenylmethyl)benzene

D

2-benzyltoluene
713-36-0

2-benzyltoluene

Conditions
ConditionsYield
With boron trifluoride diethyl etherate; water at 80℃; for 2h; regioselective reaction;A 92%
B n/a
C n/a
D n/a
glutaric anhydride,
108-55-4

glutaric anhydride,

1-bromo-octane
111-83-1

1-bromo-octane

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With [2,2]bipyridinyl; bis(1,5-cyclooctadiene)nickel (0); zinc In N,N-dimethyl acetamide at 80℃; for 12h;92%
lauric anhydride
645-66-9

lauric anhydride

phenylboronic acid
98-80-6

phenylboronic acid

A

lauric acid
143-07-7

lauric acid

B

dodecanophenone
1674-38-0

dodecanophenone

Conditions
ConditionsYield
With P(p-CH3OC6H4)3; palladium diacetate In tetrahydrofuran; water at 60℃; for 16h;A n/a
B 90%
Dodecanal
112-54-9

Dodecanal

A

lauric acid
143-07-7

lauric acid

B

lauric acid amide
1120-16-7

lauric acid amide

C

undecyl cyanide
2437-25-4

undecyl cyanide

Conditions
ConditionsYield
With H2SO4*2NH2OH; Rh(OH)x/Al2O3 In water for 9h; Heating;A 6 % Chromat.
B 89%
C 5 % Chromat.
1-tridecene
2437-56-1

1-tridecene

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With Oxone; 2-iodo-3,4,5,6-tetramethylbenzoic acid In water; acetonitrile for 24h;86%
With Oxone In water; acetonitrile for 24h; Reflux;61%
With sodium permanganate In hexane at 69℃; for 24h;13%

A

lauric acid

lauric acid

B

Conditions
ConditionsYield
With oxygen; lithium bromide In ethyl acetate at 20℃; for 6h; UV-irradiation;A 7%
B 86%
methanol

methanol

A

lauric acid

lauric acid

B

5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one
1321499-15-3

5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one

(+/-)-(3R*,4S*)-4,5-dihydroxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*)-4,5-dihydroxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*,5R*)-4-hydroxy-5-methoxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*,5R*)-4-hydroxy-5-methoxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 24h; Inert atmosphere;A 86%
B 7.8 mg
C 18.2 mg
D 2.5 mg
E 2.3 mg
thiophenol
108-98-5

thiophenol

(1R,5R)-1-dodecanoyl-4-hydroxy-4-methyl-6-oxa-3-azabicyclo[3.1.0]hexan-2-one
288854-03-5

(1R,5R)-1-dodecanoyl-4-hydroxy-4-methyl-6-oxa-3-azabicyclo[3.1.0]hexan-2-one

A

lauric acid
143-07-7

lauric acid

B

3-oxo-2-phenylsulfanyltetradecanamide
1321499-06-2

3-oxo-2-phenylsulfanyltetradecanamide

C

diphenyldisulfane
882-33-7

diphenyldisulfane

Conditions
ConditionsYield
With sodium hydrogencarbonate In methanol; water at 20℃; for 0.5h; Inert atmosphere;A 20%
B 9%
C 85%
methanol
67-56-1

methanol

lauric acid
143-07-7

lauric acid

methyl n-dodecanoate
111-82-0

methyl n-dodecanoate

Conditions
ConditionsYield
With boron trifluoride at 65℃; for 0.333333h;100%
With ethenetetracarbonitrile for 48h; Ambient temperature;99%
polyaniline hydrocloride at 70℃; for 24h;99%
lauric acid
143-07-7

lauric acid

n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide at 78℃; for 3h;100%
With thionyl chloride; N,N-dimethyl-formamide at 88℃; for 2h;99%
With thionyl chloride; sodium dodecanoylglycinate at 25℃; for 6h; Reagent/catalyst; Inert atmosphere;99.8%
lauric acid
143-07-7

lauric acid

1,1,1-trifluoro-dodecane
764-84-1

1,1,1-trifluoro-dodecane

Conditions
ConditionsYield
With pyridine; phenylsulphur trifluoride; hydrogen fluoride at 50℃; for 24h; Product distribution / selectivity; Neat (no solvent);100%
With phenylsulphur trifluoride at 20 - 100℃; for 2h; Product distribution / selectivity; Neat (no solvent);83%
With 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride at 100℃; for 2h; Reactivity;55%
lauric acid
143-07-7

lauric acid

1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

N-succinimidyl laurate
14565-47-0

N-succinimidyl laurate

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In dichloromethane for 24h;100%
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane for 3h;98%
With dicyclohexyl-carbodiimide In ethyl acetate for 6h;98%
lauric acid
143-07-7

lauric acid

1-Tetradecanol
112-72-1

1-Tetradecanol

dodecanoic acid tetradecyl ester
22412-97-1

dodecanoic acid tetradecyl ester

Conditions
ConditionsYield
With dodecylbenzene-sulphonic acid In water at 40℃; for 48h;100%
With para-dodecylbenzenesulfonic acid In water at 40℃; for 48h;99%
With triphenylphosphine-sulfur trioxide adduct In neat (no solvent) at 110℃; for 2h; Green chemistry;82%
lauric acid
143-07-7

lauric acid

monomethoxy poly(ethylene glycol)

monomethoxy poly(ethylene glycol)

dodecanoic acid monomethoxy poly(ethylene glycol) ester

dodecanoic acid monomethoxy poly(ethylene glycol) ester

Conditions
ConditionsYield
With camphor sulphuric acid for 18h; Heating;100%
lauric acid
143-07-7

lauric acid

2-chloro-1,3-dimethylimidazolinium chloride
37091-73-9

2-chloro-1,3-dimethylimidazolinium chloride

A

1,3-dimethyl-2-imidazolidinone
80-73-9

1,3-dimethyl-2-imidazolidinone

B

n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

Conditions
ConditionsYield
In tolueneA 94%
B 100%
lauric acid
143-07-7

lauric acid

2-chloro-1,3-dimethylimidazolinium chloride
37091-73-9

2-chloro-1,3-dimethylimidazolinium chloride

n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

Conditions
ConditionsYield
In toluene100%

Conditions
ConditionsYield
With sodium hydrogencarbonate; 2-oxopropanal In methanol; water at 20℃; for 1h; Inert atmosphere;100%

Conditions
ConditionsYield
In isopropyl alcohol for 1.5h; Product distribution / selectivity;100%

2-hydroxyethyltrimethylammonium laurate
88371-70-4

2-hydroxyethyltrimethylammonium laurate

Conditions
ConditionsYield
In water at 20℃;100%
In water at 100℃; for 24h;
lauric acid
143-07-7

lauric acid

di(succinimido) carbonate
74124-79-1

di(succinimido) carbonate

N-succinimidyl laurate
14565-47-0

N-succinimidyl laurate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 40℃; for 1h;100%
lauric acid
143-07-7

lauric acid

levobupivacaine
27262-47-1

levobupivacaine

[(2S)-1-butylpiperidine-2-carbonyl]-(2,6-dimethylphenyl)ammonium dodecanoate

[(2S)-1-butylpiperidine-2-carbonyl]-(2,6-dimethylphenyl)ammonium dodecanoate

Conditions
ConditionsYield
In acetonitrile at 50℃; for 6h;100%
1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

A

lauric acid
143-07-7

lauric acid

B

Dodecanal
112-54-9

Dodecanal

Conditions
ConditionsYield
With sodium hypochlorite; sodium hydrogencarbonate; potassium bromide; [4-(TEMPO-4-yloxymethyl)-1H-[1,2,3]triazol-1-ylmethyl]-PS In dichloromethane at 0℃; for 0.5h;A n/a
B 99%
With C30H24N2O7W; dihydrogen peroxide In water; acetonitrile for 22h; Reflux;A 1%
B 82%
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; oxone; potassium bromide; methyltrioxorhenium(VII) In acetonitrile at 0℃; for 4h;A 6%
B 53%
(4-oxo-3-phenyl-4H-1,1-dioxothiochromen-2-yl)methyl dodecanoate
1033736-99-0

(4-oxo-3-phenyl-4H-1,1-dioxothiochromen-2-yl)methyl dodecanoate

A

lauric acid
143-07-7

lauric acid

B

C16H10O3S
1033736-87-6

C16H10O3S

Conditions
ConditionsYield
In d(4)-methanol at 20℃; Conversion of starting material; light irradiation;A 99%
B n/a
bromobutyric acid
2623-87-2

bromobutyric acid

n-octylmagnesium chloride
38841-98-4

n-octylmagnesium chloride

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
Stage #1: bromobutyric acid With 1-methyl-pyrrolidin-2-one; tert-butylmagnesium chloride In tetrahydrofuran at -78℃; for 0.166667h; Inert atmosphere;
Stage #2: n-octylmagnesium chloride With buta-1,3-diene; nickel dichloride In tetrahydrofuran under 760.051 Torr; for 1h; Inert atmosphere; Cooling with ice;
99%
Dodecanoic acid methoxy-amide

Dodecanoic acid methoxy-amide

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With tert.-butylnitrite; water at 29℃; for 0.583333h;95%
5-dodecanolide
713-95-1

5-dodecanolide

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; W(OTf)6; hydrogen at 135℃; under 760.051 Torr; for 12h;94%
With palladium on activated carbon; W(OTf)6; hydrogen In neat (no solvent) at 135℃; under 760.051 Torr; for 12h;94%
ethyl dodecanethionate
100962-82-1

ethyl dodecanethionate

lauric acid
143-07-7

lauric acid

Conditions
ConditionsYield
With water; hydrophobic polystyrene-supported sulfonic acid for 36h; Heating;93%
ethyl 7-(5-methyltetrahydrothran-2-yl)-5-oxoheptanoate
1427085-03-7

ethyl 7-(5-methyltetrahydrothran-2-yl)-5-oxoheptanoate

ethyl 5-hydroxy-7-(5-methyltetrahydrothran-2-yl)heptanoate
1454314-43-2

ethyl 5-hydroxy-7-(5-methyltetrahydrothran-2-yl)heptanoate

A

lauric acid
143-07-7

lauric acid

B

ethyl laurate
106-33-2

ethyl laurate

Conditions
ConditionsYield
With hydrogen In ethanol; water at 240℃; under 25066.7 Torr; for 144h;A 6%
B 93%
1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

A

lauric acid
143-07-7

lauric acid

B

dodecyl laurate
13945-76-1

dodecyl laurate

Conditions
ConditionsYield
With oxygen; lithium bromide In ethyl acetate at 20℃; for 6h; UV-irradiation;A 7%
B 86%
methanol
67-56-1

methanol

3-oxo-2-phenylsulfanyltetradecanamide
1321499-06-2

3-oxo-2-phenylsulfanyltetradecanamide

2-oxopropanal
78-98-8

2-oxopropanal

A

lauric acid
143-07-7

lauric acid

B

5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one
1321499-15-3

5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one

(+/-)-(3R*,4S*)-4,5-dihydroxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*)-4,5-dihydroxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*,5S*)-4-hydroxy-5-methoxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*,5S*)-4-hydroxy-5-methoxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*,5R*)-4-hydroxy-5-methoxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

(+/-)-(3R*,4S*,5R*)-4-hydroxy-5-methoxy-5-methyl-3-phenylsulfanyl-2-pyrrolidinone

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 24h; Inert atmosphere;A 86%
B 7.8 mg
C 18.2 mg
D 2.5 mg
E 2.3 mg
lauric acid
143-07-7

lauric acid

pregabilin
148553-50-8

pregabilin

(S)-3-(aminomethyl)-5-methylhexanoic acid laurate
1414928-47-4

(S)-3-(aminomethyl)-5-methylhexanoic acid laurate

Conditions
ConditionsYield
In isopropyl alcohol for 1.5h; Product distribution / selectivity;100%
lauric acid
143-07-7

lauric acid

cholinium hydrogen carbonate
78-73-9

cholinium hydrogen carbonate

2-hydroxyethyltrimethylammonium laurate
88371-70-4

2-hydroxyethyltrimethylammonium laurate

Conditions
ConditionsYield
In water at 20℃;100%
In water at 100℃; for 24h;
lauric acid
143-07-7

lauric acid

Fmoc-glycine-2-chlorotrityl resin

Fmoc-glycine-2-chlorotrityl resin

N-(fluoren-9-ylmethoxycarbonyl)glycine
29022-11-5

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Lys-OH
105047-45-8

Fmoc-Lys-OH

n-dodecanoyl-HN-Lys(Boc)-Lys(Boc)-Lys(Boc)-Gly-Gly-CO2H

n-dodecanoyl-HN-Lys(Boc)-Lys(Boc)-Lys(Boc)-Gly-Gly-CO2H

Conditions
ConditionsYield
Stage #1: Fmoc-glycine-2-chlorotrityl resin With piperidine In N,N-dimethyl-formamide 2-Cl-Trt-Resin;
Stage #2: N-(fluoren-9-ylmethoxycarbonyl)glycine With benzotriazol-1-ol; diisopropyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 1h; 2-Cl-Trt-Resin;
Stage #3: lauric acid; Fmoc-Lys-OH Further stages;
100%
lauric acid
143-07-7

lauric acid

palladium diacetate
3375-31-3

palladium diacetate

palladium dodecanoate

palladium dodecanoate

Conditions
ConditionsYield
In cyclohexane at 40℃; Solvent;100%
lauric acid
143-07-7

lauric acid

1-Hexadecanol
36653-82-4

1-Hexadecanol

undecanyl cetanoate
20834-06-4

undecanyl cetanoate

Conditions
ConditionsYield
With zirconium(IV) oxychloride In 1,3,5-trimethyl-benzene at 162℃; for 24h;99.9%
With choline chloride; zinc(II) chloride at 110℃; for 8h;99%
lipase In hexane for 4h;94%
lauric acid
143-07-7

lauric acid

trichlorovinylsilane
75-94-5

trichlorovinylsilane

Octanoic acid
124-07-2

Octanoic acid

n-tetradecanoic acid
544-63-8

n-tetradecanoic acid

C36H68O6Si
1330066-17-5

C36H68O6Si

Conditions
ConditionsYield
In toluene at 60 - 150℃; for 4h;99.82%
lauric acid
143-07-7

lauric acid

ascorbic acid
50-81-7

ascorbic acid

6-O-dodecanoyl-L-ascorbic acid
16690-40-7

6-O-dodecanoyl-L-ascorbic acid

Conditions
ConditionsYield
With Amberlyst 15 ion exchange resin In ethanol; water at 60℃; for 3h; Temperature;99.2%
With sulfuric acid
With sulfuric acid at 40℃;
With lipase from Candida antarctica type B (Chirazyme(R) L-2 C2) In acetone at 50℃;
With Chirazyme(R) L-2 C2 In acetone at 55℃; for 24h;

Lauric acid Consensus Reports

Reported in EPA TSCA Inventory.

Lauric acid Specification

The IUPAC name of Lauric acid is dodecanoic acid. With the CAS registry number 143-07-7, it is also named as 1-Undecanecarboxylic acid. The product's categories are Miscellaneous Natural Products; Alkylcarboxylic Acids; Biochemistry; Color Former & Related Compounds; Functional Materials; Higher Fatty Acids & Higher Alcohols; Monofunctional & alpha,omega-Bifunctional Alkanes; Monofunctional Alkanes; Saturated Higher Fatty Acids; Sensitizer, and the other registry numbers are 203714-07-2; 7632-48-6; 8000-62-2; 8045-27-0. Besides, it is white solid with a faint odour of bay oil, which should be stored in a cool, ventilated and dry place. This chemical is stable, combustible, and incompatible with bases, oxidizing agents, reducing agents. In addition, its molecular formula is C12H24O2 and molecular weight is 200.32.

The other characteristics of this product can be summarized as: (1)EINECS: 205-582-1; (2)ACD/LogP: 5.03; (3)# of Rule of 5 Violations: 1; (4)ACD/LogD (pH 5.5): 4.23; (5)ACD/LogD (pH 7.4): 2.44; (6)ACD/BCF (pH 5.5): 627.67; (7)ACD/BCF (pH 7.4): 10.08; (8)ACD/KOC (pH 5.5): 2082.83; (9)ACD/KOC (pH 7.4): 33.43; (10)#H bond acceptors: 2; (11)#H bond donors: 1; (12)#Freely Rotating Bonds: 10; (13)Index of Refraction: 1.447; (14)Molar Refractivity: 59.2 cm3; (15)Molar Volume: 221.2 cm3; (16)Surface Tension: 33.2 dyne/cm; (17)Density: 0.905 g/cm3; (18)Flash Point: 134.1 °C; (19)Melting Point: 44-46 °C; (20)Enthalpy of Vaporization: 56.59 kJ/mol; (21)Boiling Point: 296.1 °C at 760 mmHg; (22)Vapour Pressure: 0.000661 mmHg at 25 °C.

Preparation of Lauric acid: this chemical can be prepared by the hydrolysis and separation of coconut oil and other vegetable oils.

Uses of Lauric acid: this chemical can be used in laboratory investigations of freezing-point depression. It is antibacterial, antioxidant, antiviral and COX-1-2 inhibitor which is also used for Benign prostatic hyperplasia in traditional medicinal remedies. Moreover, it is widely used as surfactant. The product is the material used in perfume industry and pharmaceutical industry. Similarly, it can react with Methanol to get Dodecanoic acid methyl ester.



This reaction needs Tetracyanoethylene at ambient temperature for 48 hours. The yield is 99 %.

When you are using this chemical, please be cautious about it as the following: it is irritating to eyes and skin. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
(1)SMILES: O=C(O)CCCCCCCCCCC
(2)InChI: InChI=1/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
(3)InChIKey: POULHZVOKOAJMA-UHFFFAOYAP

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 131mg/kg (131mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Acta Pharmacologica et Toxicologica. Vol. 18, Pg. 141, 1961.
rat LD50 oral 12gm/kg (12000mg/kg)   Food & Drug Research Laboratories, Inc., Papers. Vol. 123, Pg. -, 1976.

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View