METHYL PROPIONATE supplier

Name
Methyl propionate
EINECS 209-060-4
CAS No. 554-12-1
Article Data249
CAS DataBase
Density 0.898 g/cm³
Solubility 5 g/100 mL at 20 °C in water
Melting Point -88 °C
Formula C₄H₈O₂
Boiling Point 67.9 °C at 760 mmHg
Molecular Weight 88.1063
Flash Point 6.1 °C
Transport Information UN 1248 3/PG 2
Appearance colourless liquid
Safety 16-24-29-33
Risk Codes 11-20
Molecular Structure
Hazard Symbols F, Xn
Synonyms Propionicacid, methyl ester (8CI);Methyl propanoate;Methylpropylate;NSC 9375;
PSA 26.30000
LogP 0.56940

Synthetic route

: 67-56-1
methanol

: 802294-64-0
propionic acid

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With boron trifluoride at 65℃; for 0.333333h;	100%
With Dowex 50W×2 hydrogen form at 103 - 108℃; Reagent/catalyst; Autoclave; Large scale;	98.6%
With bis(acetylacetonato)dioxidomolybdenum(VI) for 8h; Heating;	72%

: 292638-85-8
acrylic acid methyl ester

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With hydrogen; palladium(II) complex of ferrocenylamine sulfide (2) In acetone under 4137.2 Torr; for 0.25h; or with catalyst 3, 0.75 h;	100%
With [Ir(1-(1′-methylpyrazole)-3-(4′-methylphenyl)triazenide)Cp*Cl]; isopropyl alcohol at 90℃; for 6h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Glovebox;	99%
With tetrahydroxydiboron; water; sodium hydrogencarbonate In tetrahydrofuran at 60℃; for 8h; Inert atmosphere;	99%

: 74-85-1
ethene

: [PdH(PPh3)3](TsO)

: 201230-82-2
carbon monoxide

: 771476-64-3
trans-[Pd(COEt)(OTs)(PPh3)2]

B: 554-12-1
propanoic acid methyl ester

: 1478674-03-1
[Pd(COEt)(PPh3)3](TsO)

Conditions

Conditions	Yield
at -80.16 - 49.84℃; under 3000.3 Torr; for 0.0133333h;	A 0.1% B 100% C n/a

...Expand

: 67-56-1
methanol

: 74-85-1
ethene

: 201230-82-2
carbon monoxide

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With methanesulfonic acid; palladium diacetate; bis(phosphaadamantyl)diphosphine at 90℃;	99%
With α,α′-bis(2-pyridyl(tert-butyl)phosphino)-o-xylene; palladium dichloride at 80℃; under 15001.5 - 22502.3 Torr; for 20h; Reagent/catalyst; Pressure; Inert atmosphere; Autoclave;	99%
With bis(acetylacetonato)palladium(II); 1,1’-ferrocenediyl-bis(tert-butyl(pyridin-2-yl)phosphine); toluene-4-sulfonic acid at 80℃; for 0.166667h; Catalytic behavior; Reagent/catalyst; Temperature; Autoclave; Inert atmosphere;	99%

...Expand

: 67-56-1
methanol

: 771476-64-3
trans-[Pd(COEt)(OTs)(PPh3)2]

: 201230-82-2
carbon monoxide

: 771476-65-4
trans-[Pd(COOMe)(OTs)(PPh3)2]

B: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With toluene-4-sulfonic acid; triphenylphosphine In methanol Pd complex, (0.1 mmol) reacted with MeOH containing PPh3 (0.1 mmol) + p-toluenesulfonic acid (0.1 mmol) satd. with CO (ca. 20 min); pptd. with cold H2O; suspn. filtered; ppt. washed with cold H2O; dried (vac.);	A 90% B 99%

...Expand

: 67-56-1
methanol

: 50-00-0
formaldehyd

: 74-85-1
ethene

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With palladium diacetate; toluene-4-sulfonic acid; 1,2-bis[di(t-butyl)phosphinomethyl]benzene at 100℃; under 3750.38 Torr; for 20h; Inert atmosphere; Autoclave; regioselective reaction;	99%

...Expand

: 802294-64-0
propionic acid

: 616-38-6
carbonic acid dimethyl ester

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With triethylamine at 160℃; for 5h; Autoclave; Green chemistry;	98%
With diiron nonacarbonyl at 180℃; for 1h; Sealed tube;

: 922-67-8
propynoic acid methyl ester

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With tetrahydroxydiboron; water; sodium hydrogencarbonate In methanol at 80℃; for 12h;	98%

: 67-56-1
methanol

: 40424-08-6
1,1'-(2-oxoimidazolidine-1,3-diyl)bis(propan-1-one)

A: 120-93-4
imidazolidone

B: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With C17H23BN2O at 50℃; under 760.051 Torr; for 15h; Inert atmosphere; chemoselective reaction;	A 97% B n/a

...Expand

: 67-56-1
methanol

: 40424-08-6
1,1'-(2-oxoimidazolidine-1,3-diyl)bis(propan-1-one)

A: 554-12-1
propanoic acid methyl ester

B: 55150-33-9
1-propionyl-2-oxo-imidazolidine

Conditions

Conditions	Yield
With C17H23BN2O at 25℃; under 760.051 Torr; for 0.25h; Inert atmosphere; chemoselective reaction;	A n/a B 96%

...Expand

: 17639-93-9
2-chloro-propionic acid methyl ester

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With sodium chloride; tin(ll) chloride In tetrahydrofuran; water for 2h; Heating; further sodium halides or pseudo-halides and metal halides;	95%
With sodium hydrogensulfide; tin(ll) chloride In tetrahydrofuran; water for 2h; Heating;	95%
With sodium iodide; tin(ll) chloride In tetrahydrofuran; water for 2h; Heating;	92%
With sodium tetrahydroborate; tin(ll) chloride In tetrahydrofuran for 2h; Heating;	90%

: 67-56-1
methanol

: 51430-68-3
3,4-dichloro-(E)-3-hexene

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With ozone at -40℃; for 43h;	92%

: 74-85-1
ethene

: 107-31-3
Methyl formate

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With ruthenium trichloride; tetraethylammonium iodide; bis(triphenylphosphine)iminium chloride In N,N-dimethyl-formamide at 165℃; under 18751.9 Torr; for 5h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Autoclave;	85.4%
With ruthenium trichloride; tetraethylammonium iodide In N,N-dimethyl-formamide at 190℃; under 45003.6 Torr; for 1h; Product distribution; var. solvents, reaction times, promoters, and ruthenium complexes, also in the presence of CO;
With tris(triphenylphosphine)ruthenium(II) chloride at 190 - 200℃; under 7500.6 Torr; for 18h; Product distribution; other alkyl formate; var. solvents, var. substrates concentrations;
With 1-butyl-1-methylpyrrolidinium chloride; dicobalt octacarbonyl; dichlorotricarbonylruthenium(II) dimer at 120℃; under 15001.5 Torr; for 15h; Product distribution / selectivity;

: [DBUH][O2COMe]

: 123-62-6
propionic acid anhydride

A: 554-12-1
propanoic acid methyl ester

B: 51301-57-6
1,8-diazabicyclo[5.4.0]undec-7-enium propanoate

Conditions

Conditions	Yield
In methanol at 20℃; for 1h;	A 85% B n/a

...Expand

: 109-87-5
Dimethoxymethane

: 123-62-6
propionic acid anhydride

A: 554-12-1
propanoic acid methyl ester

B: 70767-92-9
propionic acid methoxymethyl ester

Conditions

Conditions	Yield
With Amberlyst 15 at 50 - 55℃; for 0.0833333h; Heating / reflux;	A n/a B 83.6%

...Expand

: 67-56-1
methanol

: 123-38-6
propionaldehyde

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With sodium carbonate; N,N'-diiodo-N,N'-1,2-ethanediylbis(p-toluenesulphonamide) at 20℃; for 40h;	80%
With magnesium hydroxide; oxygen at 90℃; under 2250.23 Torr; for 2h;

: 108-24-7
acetic anhydride

: 107-87-9
2-Pentanone

A: 554-12-1
propanoic acid methyl ester

B: 623-42-7
butanoic acid methyl ester

Conditions

Conditions	Yield
With oxygen; manganese(III) triacetate dihydrate at 90℃; under 3750.38 Torr; for 10h; Autoclave;	A 21% B 79%

...Expand

: 78-93-3
butanone

A: 554-12-1
propanoic acid methyl ester

B: 141-78-6
ethyl acetate

Conditions

Conditions	Yield
With hydrogenchloride In chloroform at 20℃; for 14h; Baeyer-Villiger oxidation;	A 14% B 78%
With (η5-C5H4SiMe3)2NbH(O)C=CPh2 at 25℃;
With sec-decanepersulfonic acid In acetonitrile at 17℃; Rate constant;

: 547-64-8
methyl lactate

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With hydrogen In methanol at 220℃; under 37503.8 Torr; for 12h; Reagent/catalyst;	77%
With nickel(II) ferrite; hydrogen In methanol at 220℃; under 37503.8 Torr; for 12h; Catalytic behavior; Reagent/catalyst; Temperature;	75%

: 94070-38-9
trans-MeOIr(CO)(PPh3)2

: 75-07-0
acetaldehyde

A: 17250-59-8
HIr(PPh3)2(CO)2

B: 79-20-9
acetic acid methyl ester

C: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
In cyclohexane in dry box onto the degassed (vac.) soln. of complex (in a pressure tube fitted with a Teflon stopcock) CH3CHO distilled, 5 d reacted at room temp.; not isolated, spect. detection by IR and NMR in the soln.;	A n/a B 75% C n/a

...Expand

: 67-56-1
methanol

: 27126-76-7
[hydroxy(tosyloxy)iodo]benzene

: 123-62-6
propionic acid anhydride

A: 591-50-4
iodobenzene

B: 554-12-1
propanoic acid methyl ester

C: 66648-29-1
methyl 2-{[(4-methylphenyl)sulfonyl]oxy}propanoate

Conditions

Conditions	Yield
Stage #1: [hydroxy(tosyloxy)iodo]benzene; propionic acid anhydride at 100℃; for 0.333333h; Stage #2: methanol With toluene-4-sulfonic acid for 4h; Heating;	A n/a B n/a C 73%

...Expand

: tri(1-naphthyl)phosphonium tris(pentafluorophenyl)borohydride

: 292638-85-8
acrylic acid methyl ester

A: 554-12-1
propanoic acid methyl ester

B: C34H28O2P(1+)

Conditions

Conditions	Yield
In dichloromethane-d2 for 12h; Glovebox; Sealed tube;	A 28% B 72%

...Expand

: 616-42-2
dimethylsulfite

: 802294-64-0
propionic acid

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
sulfuric acid Heating;	70%

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 109-62-6
ethylmercuric acetate

: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With Wilkinson's catalyst at 65 - 100℃; under 5171.5 - 25857.4 Torr;	66%

...Expand

: 67-56-1
methanol

: 123-62-6
propionic acid anhydride

: 105551-42-6
(mesyloxyhydroxyiodo)benzene

A: 591-50-4
iodobenzene

B: 554-12-1
propanoic acid methyl ester

C: methyl 2-((methanesulfonyl)oxy)propanoate

Conditions

Conditions	Yield
Stage #1: propionic acid anhydride; (mesyloxyhydroxyiodo)benzene at 100℃; for 0.333333h; Stage #2: methanol With toluene-4-sulfonic acid for 4h; Heating;	A n/a B n/a C 66%

...Expand

: 67-56-1
methanol

: 123-62-6
propionic acid anhydride

: {hydroxy[(+)-10-camphosulfonyloxy]iodo}benzene

A: 591-50-4
iodobenzene

B: 554-12-1
propanoic acid methyl ester

C: methyl 2-[(+)-camphorsulfonyloxy]propionate

Conditions

Conditions	Yield
Stage #1: propionic acid anhydride; {hydroxy[(+)-10-camphosulfonyloxy]iodo}benzene at 100℃; for 0.333333h; Stage #2: methanol With toluene-4-sulfonic acid for 4h; Heating;	A n/a B n/a C 62%

...Expand

: 547-64-8
methyl lactate

A: 71-23-8
propan-1-ol

B: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
With hydrogen In methanol at 220℃; under 37503.8 Torr; for 12h;	A 10% B 60%

: 67-56-1
methanol

: 39739-45-2
methylpropioimidate hydrochloride

A: 24823-81-2
trimethoxypropane

B: 554-12-1
propanoic acid methyl ester

Conditions

Conditions	Yield
at 20℃; for 48h;	A 59% B n/a

...Expand

: 1094249-99-6
tri(o-tolyl)phosphonium tris(pentafluorophenyl)borohydride

: 292638-85-8
acrylic acid methyl ester

A: 554-12-1
propanoic acid methyl ester

B: C25H28O2P(1+)

Conditions

Conditions	Yield
In dichloromethane-d2 for 12h; Glovebox; Sealed tube;	A 47% B 53%

...Expand

: 6164-79-0
methyl pyrazine-2-carboxylate

: 554-12-1
propanoic acid methyl ester

: 324737-10-2
methyl 2-methyl-3-(pyrazin-2-yl)-3-oxopropionate

Conditions

Conditions	Yield
Stage #1: methyl pyrazine-2-carboxylate With sodium hydride In toluene at 15 - 25℃; for 0.5h; Industrial scale; Stage #2: propanoic acid methyl ester In methanol; toluene at 15 - 40℃; Temperature; Solvent; Reagent/catalyst; Industrial scale;	100%
Stage #1: propanoic acid methyl ester With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.5h; Stage #2: methyl pyrazine-2-carboxylate In tetrahydrofuran at 0 - 25℃; for 3.5h; Stage #3: With ammonium chloride In tetrahydrofuran for 0.5h;	89%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 5h; Inert atmosphere;	79%
With NaH; ammonium chloride In toluene

: 554-12-1
propanoic acid methyl ester

: (2R,6R)-6-[(methoxymethoxy)methyl]-1-(phenylmethyl)-2-[3-[[tris(1-methylethyl)silyl]oxy]propyl]-2-piperidinecarboxaldehyde

: (2R,6R)-β-hydroxy-6-[(methoxymethoxy)methyl]-α-methyl-1-(phenylmethyl)-2-[3-[[tris(1-methylethyl)silyl]oxy]propyl]-2-piperidinepropanoic acid methyl ester

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at -78℃;	99%
Stage #1: propanoic acid methyl ester With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 1.33333h; Stage #2: (2R,6R)-6-[(methoxymethoxy)methyl]-1-(phenylmethyl)-2-[3-[[tris(1-methylethyl)silyl]oxy]propyl]-2-piperidinecarboxaldehyde In tetrahydrofuran; hexane at -78℃; for 0.75h; Aldol condensation; Stage #3: With ammonium chloride In tetrahydrofuran; hexane	36%

: 4833-50-5
cyclohexanespiro-2'-(imidazolidin-4'-thione)-5'-spirocyclohexane

: 554-12-1
propanoic acid methyl ester

: C17H26N2O2S

Conditions

Conditions	Yield
In chloroform-d1 at 20 - 45℃; for 96h;	99%

: C11H18N2O2S

: 554-12-1
propanoic acid methyl ester

: C15H22N2O4S

Conditions

Conditions	Yield
In chloroform-d1 at 20 - 45℃; for 112h;	99%

: 554-12-1
propanoic acid methyl ester

: 127-06-0
acetone oxime

: O-propanoyl acetone oxime

Conditions

Conditions	Yield
With sodium methylate at 70℃; under 760.051 Torr; for 8h; Temperature; Reagent/catalyst; Large scale;	98.2%

: 554-12-1
propanoic acid methyl ester

: 112-53-8
1-dodecyl alcohol

: 6221-93-8
1-dodecyl propionate

Conditions

Conditions	Yield
cerium (IV) sulfate; silica gel for 1h; Heating;	98%

: 554-12-1
propanoic acid methyl ester

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

: 141-34-4
triethylene glycol dipropionate

Conditions

Conditions	Yield
With potassium carbonate at 90 - 95℃;	98%

: 149105-10-2
1-(4-methoxy-3-(trifluoromethyl)phenyl)ethanone

: 554-12-1
propanoic acid methyl ester

: 1-(4-methoxy-3-(trifluoromethyl)phenyl)pentane-1,3-dione

Conditions

Conditions	Yield
Stage #1: 1-[4-Methoxy-3-(trifluoromethyl)phenyl]ethanone With sodium hydride In diethyl ether; mineral oil at 0℃; for 0.5h; Stage #2: propanoic acid methyl ester In diethyl ether; mineral oil at 40℃; for 12h;	97%

: 554-12-1
propanoic acid methyl ester

: 1219607-85-8
(RS)-N-tert-butanesulfinyl-(3,3,3)-trifluoroacetaldimine

: methyl (2S,3S,2'R)-4,4,4-trifluoro-3-(tert-butylsulfinamino)-2-methylbutyrate

Conditions

Conditions	Yield
Stage #1: propanoic acid methyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -80℃; for 0.5h; Stage #2: With triisopropoxytitanium(IV) chloride In tetrahydrofuran; hexane at -80℃; for 0.666667h; Stage #3: (RS)-N-tert-butanesulfinyl-(3,3,3)-trifluoroacetaldimine In tetrahydrofuran; hexane at -80℃; for 3h; diastereoselective reaction;	96.5%

: 554-12-1
propanoic acid methyl ester

: 220315-18-4
(RS,E)-N-ethylidene-2-methylpropane-2-sulfinamide

: 220315-34-4
(RS,2S,3R)-(-)-methyl 3-(N-tert-butanesulfinyl)amino-2-methylbutanoate

Conditions

Conditions	Yield
Stage #1: propanoic acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h; Stage #2: With triisopropoxytitanium(IV) chloride In tetrahydrofuran at -78℃; for 0.5h; Stage #3: (RS,E)-N-ethylidene-2-methylpropane-2-sulfinamide In tetrahydrofuran at -78℃; for 3h; Further stages.;	96%
With triisopropoxytitanium(IV) chloride; lithium diisopropyl amide In tetrahydrofuran at -78℃;	92%

: 554-12-1
propanoic acid methyl ester

: 343338-28-3
(S)-2-methylpropane-2-sulfinamide

: C8H17NO2S

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 103℃; Inert atmosphere; Schlenk technique;	96%

: 6512-99-8
ethyl oleate

: 554-12-1
propanoic acid methyl ester

: 112-62-9
octadec-9-enoic acid methyl ester

Conditions

Conditions	Yield
titanium(IV) tetraethanolate for 86h; Heating;	95%

: 554-12-1
propanoic acid methyl ester

: 76042-40-5
2-(2-cyclobutanonyl)-6-bromo-3,4-dihydronaphthalene

: 76042-59-6
2-(6-bromo-3,4-dihydronaphthalen-2-yl)-1-(1-(carbmethoxy)ethyl)cyclobutanol

Conditions

Conditions	Yield
With lithium diisopropyl amide In diethyl ether at -10℃;	95%

: 554-12-1
propanoic acid methyl ester

: 104-88-1
4-chlorobenzaldehyde

: 53059-73-7
α-Methyl-4-chlorzimtsaeure-methylester

Conditions

Conditions	Yield
With P(i-BuNCH2CH2)3N at 50℃; for 6h;	95%

: 554-12-1
propanoic acid methyl ester

: 493006-19-2
methyl 3,5-dimethyl-4-[(1'-iodo-2',2'-dimethyl)propyl]pyrrole-2-carboxylate

: methyl 3,5-dimethyl-4-[2',2'-dimethyl-1'-(1"-methoxycarbonylethyl)propyl]-1H-pyrrole-2-carboxylate

Conditions

Conditions	Yield
Stage #1: propanoic acid methyl ester With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 1h; Stage #2: methyl 3,5-dimethyl-4-[(1'-iodo-2',2'-dimethyl)propyl]pyrrole-2-carboxylate With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran; hexane at -78 - -55℃;	95%

: 554-12-1
propanoic acid methyl ester

: (SS)-2-methyl-N-(2,2,2-trifluoroethylidene)-propane-2-sulfinamide

: methyl (2R,3R,2'S)-4,4,4-trifluoro-3-(tert-butylsulfinamino)-2-methylbutyrate

Conditions

Conditions	Yield
Stage #1: propanoic acid methyl ester With n-butyllithium; diisopropylamine In diethyl ether; hexane at -80℃; for 0.5h; Stage #2: With triisopropoxytitanium(IV) chloride In diethyl ether; hexane at -80℃; for 0.666667h; Stage #3: (SS)-2-methyl-N-(2,2,2-trifluoroethylidene)-propane-2-sulfinamide In diethyl ether; hexane at -80℃; for 3h; diastereoselective reaction;	95%

: 554-12-1
propanoic acid methyl ester

: 76042-39-2
2-(2-cyclobutanonyl)-6-methoxy-3,4-dihydronaphthalene

: 76043-11-3
2-[1-Hydroxy-2-(6-methoxy-3,4-dihydro-naphthalen-2-yl)-cyclobutyl]-propionic acid methyl ester

Conditions

Conditions	Yield
With lithium diisopropyl amide In diethyl ether at -10℃;	94%

: 554-12-1
propanoic acid methyl ester

: 105224-90-6
dimethylaminobis(trifluoromethyl)borane

: 148298-53-7
1-methoxycarbonylethyl-bis(trifluoromethyl)borane-dimethylamine

Conditions

Conditions	Yield
In pentane dropwise addn. of (CF3)2BNMe2 to a stirred soln. of the carbonyl compound in dry pentane at 4°C; warmed to room temp. with stirring (1 h);; removal of solvent and volatile by-products in vac. at room temp., purifn. by sublimation in vac.; elem. anal.;;	94%

: 554-12-1
propanoic acid methyl ester

: 913335-50-9
[iridium(I)(2,6-bis{(di-tert-butylphosphino)methyl}pyridine)(cyclooctene)](tetrafluoroborate)

: [iridium(I)(2,6-bis{(di-tert-butylphosphino)methyl}pyridine)(H)(methylpropanoate(-H))](tetrafluoroborate)

Conditions

Conditions	Yield
at 60℃; for 20h; Inert atmosphere; Schlenk technique;	94%

METHYL PROPIONATE Chemical Properties

The molecular formula of METHYL PROPIONATE(554-12-1) is C₄H₈O₂ and its formula weight is 88.12g/mol.The appearance of METHYL PROPIONATE(554-12-1) is colourless and ruit flavor liquid.Its EINECS is 209-060-4.Its liansport information is UN 1248.The density of METHYL PROPIONATE(554-12-1) is 0.915 g/mL at 25 °C(lit.) and it has a melting point of -88 °C .The boiling point is 79 °C(lit.).The refractive index is about n20/D 1.376(lit.) and molar refractivity is 22.35 cm³.Its flash point is 43 °F and the vapor pressure is 40 mm Hg ( 11 °C).Molar volume is 98 cm³and polarizability is 8.86 10-24cm³.Surface tension is 23.5 dyne/cm and enthalpy of vaporization is 32.24 kJ/mol.METHYL PROPIONATE(554-12-1) has the property of being dissolved in alcohols, ethers, hydrocarbons and other organic solvents, slightly soluble in water. The solubility of METHYL PROPIONATE(554-12-1) is 5 g/100 mL at 20 °C in water.
The chemical synonyms of METHYL PROPIONATE(554-12-1) are C2H5COOCH3;femanumber2742;Methyl ester of propanoic acid;Methylester kyseliny propionove;methylesterkyselinypropionove;Propionate de methyle;propionatedemethyle and propionatedemethyle(french).Its product categories is Organics;Analytical Chemistry;Fatty Acid Methyl Esters (GC Standard);Standard Materials for GC;FAMEs;Fatty AcidsAlphabetic;Lipid Analytical Standards;M;META - METHSaturated fatty acids and derivatives;Methyl EstersFA/FAME/Lipids/Steroids;Neats&Single Component Solutions;Other Lipid Related Products;C2 to C5Saturated fatty acids and derivatives;Carbonyl Compounds;Esters;Methyl Esters;Alphabetical Listings;Flavors and Fragrances and M-N. The molecular structure of METHYL PROPIONATE(554-12-1) is

METHYL PROPIONATE Uses

It can be used in medicine, pesticides and intermediates of perfume .

METHYL PROPIONATE Production

It is derived from the esterification of propionic acid with methanol : CH₃CH₂COOH + CH₃OH → CH₃CH₂COOCH₃ + H₂O

METHYL PROPIONATE Toxicity Data With Reference

1.	skn-rbt 500 mg/24H MOD	FCTOD7 Food and Chemical Toxicology. 20 (Suppl)(1982),765.
2.	orl-rat LD50:5 g/kg	FCTOD7 Food and Chemical Toxicology. 20 (Suppl)(1982),765.
3.	orl-mus LD50:3460 mg/kg	GTPZAB Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 18 (3)(1974),48.
4.	ihl-mus LC50:27 g/m3	GTPZAB Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 18 (3)(1974),48.
5.	orl-rbt LDLo:2550 mg/kg	AMIHAB AMA Archives of Industrial Health. 21 (1960),100.

METHYL PROPIONATE Consensus Reports

Reported in EPA TSCA Inventory.

METHYL PROPIONATE Safety Profile

Moderately toxic by ingestion. Mildly toxic by inhalation. A skin irritant. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. Explosive in the form of vapor when exposed to heat or flame. To fight fire, use foam, CO₂, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. It is flammable, dangerous fire risk, explosive limits in air 2.5–13%. Hazard codes is

F,Xn . Risk codes is R11;R20. Safety description is S16;S24;S29;S33.

METHYL PROPIONATE Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

METHYL PROPIONATE Specification

Its extinguishing agents is dry powder, dry sand, carbon dioxide, foam and 1211 extinguishing agent.

Product Name

Methyl propionate

Synthetic route

METHYL PROPIONATE Chemical Properties

METHYL PROPIONATE Uses

METHYL PROPIONATE Production

METHYL PROPIONATE Toxicity Data With Reference

METHYL PROPIONATE Consensus Reports

METHYL PROPIONATE Safety Profile

METHYL PROPIONATE Standards and Recommendations

METHYL PROPIONATE Specification

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