Monoethyl phthalate supplier

Name
ETHYL PHTHALATE MONO
EINECS
CAS No. 2306-33-4
Article Data23
CAS DataBase
Density 1.241g/cm³
Solubility
Melting Point 46-48°C
Formula C10H10 O4
Boiling Point 339.6°Cat760mmHg
Molecular Weight 194.187
Flash Point 135.3°C
Transport Information
Appearance
Safety Moderately toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating vapors.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1,2-Benzenedicarboxylicacid, monoethyl ester (9CI); Phthalic acid, ethyl ester (6CI,7CI); Phthalicacid, monoethyl ester (8CI); Ethyl 2-carboxybenzoate; Monoethyl phthalate
PSA 63.60000
LogP 1.56150

Synthetic route

: 85-44-9
phthalic anhydride

: 64-17-5
ethanol

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate for 0.0125h; further reagents;	93%
With 1-hydro-3-(3-sulfopropyl)-imidazolium 4-methyl-benzenesulfonate at 60℃; Heating;	93%
at 60 - 80℃;	91%

: 84-66-2
Diethyl phthalate

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
With potassium hydroxide In water; dimethyl sulfoxide at 0℃; for 2h; Solvent; Reagent/catalyst;	93%
With water; potassium hydroxide In dimethyl sulfoxide at 0℃; for 2h; Solvent;	93%
With Tris-HCl buffer; mouse hepatic microsomal esterase ES46.5K In acetone at 37℃; pH=8.0; Enzyme kinetics; Further Variations:; Reagents; Hydrolysis;
With helium; water at 19.85℃; pH=12; Kinetics; Activation energy; Thermodynamic data; Irradiation;
Multi-step reaction with 2 steps 1: sodium hydroxide / water / pH 10 / UV-irradiation 2: sodium hydroxide / water / pH 10 / UV-irradiation View Scheme

: 124-38-9
carbon dioxide

: 1829-28-3
ethyl 2-iodobenzoate

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
Stage #1: ethyl 2-iodobenzoate With phenyllithium In tetrahydrofuran; diethyl ether; cyclohexane at -60℃; for 3.88889E-06h; Flow reactor; Stage #2: carbon dioxide In tetrahydrofuran; diethyl ether; cyclohexane at -60℃; Flow reactor;	89%

: 33672-94-5
Ethylallylphthalat

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
With tetraethylammonium tosylate; tetrakis(triphenylphosphine) palladium(0) In acetonitrile Electrochemical reaction, Pb cathode, Pt anode;	87%

: 667-27-6
Ethyl bromodifluoroacetate

: 65-85-0
benzoic acid

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate; copper(II) acetate monohydrate at 100℃; for 24h; Reagent/catalyst; Sealed tube;	81%

: 124-38-9
carbon dioxide

: 6091-64-1
2-bromobenzoic acid ethyl ester

: 584-08-7
potassium carbonate

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
With nickel(II) bromide dimethoxyethane; 2.9-dimethyl-1,10-phenanthroline; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; C60H36N2 In N,N-dimethyl-formamide at 20℃; for 24h; Molecular sieve; Irradiation;	73%

...Expand

: 64-17-5
ethanol

: 21752-35-2
(R)-2-((1-phenylethyl)carbamoyl)benzoic acid

A: 2306-33-4
monoethyl phthalate

B: 3886-69-9
(R)-1-phenyl-ethyl-amine

Conditions

Conditions	Yield
at 60℃; for 12h;	A 37% B 40%

...Expand

: 85-44-9
phthalic anhydride

: 64-17-5
ethanol

A: 2306-33-4
monoethyl phthalate

B: 88-99-3
benzene-1,2-dicarboxylic acid

Conditions

Conditions	Yield
for 1h; Reflux;	A n/a B 32%
With water Rate constant; Product distribution; var. ratio of solvents;

...Expand

: 64-17-5
ethanol

: 85-01-8
phenanthrene

A: 86-73-7
9H-fluorene

B: 2005-10-9
6H-benzo[c]chromen-6-one

C: 486-25-9
9-fluorenone

D: 1430-97-3
2-methyl-9H-fluorene

E: 2306-33-4
monoethyl phthalate

F: 5807-65-8
diethyl biphenyl 2,2'-dicarboxylate

G: 4425-82-5
9-methylene-fluorene

H: 605-87-8
3-Phenanthrol

I: 863305-32-2
diphenic acid

J: 19926-49-9
2-phenylbenzoic acid ethyl ester

K: 604-84-2
phenanthrene-9,10-diol

L: 27428-70-2
2,2'-diphenic acid ethyl ester

M: 84-11-7
9,10-phenanthrenequinone

Conditions

Conditions	Yield
With water UV-irradiation; Green chemistry;	A n/a B 23% C 19% D n/a E n/a F n/a G n/a H n/a I n/a J n/a K n/a L n/a M n/a

...Expand

: 85-44-9
phthalic anhydride

: 64-17-5
ethanol

: 151-50-8
potassium cyanide

: 2306-33-4
monoethyl phthalate

...Expand

: 64-17-5
ethanol

: 877-24-7
potassium hydrogen phthalate

: 541-41-3
chloroformic acid ethyl ester

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
Zersetzen des Produktes mit Wasser;

...Expand

: 64-17-5
ethanol

: 36053-26-6
N-thiocarbamoyl-phthalamic acid

copper: copper

A: 2306-33-4
monoethyl phthalate

B: 17356-08-0
thiourea

Conditions

Conditions	Yield
at 120 - 130℃; im geschlossenen Rohr;

...Expand

: 64-17-5
ethanol

: 36053-26-6
N-thiocarbamoyl-phthalamic acid

HgO: HgO

A: 2306-33-4
monoethyl phthalate

B: 88-99-3
benzene-1,2-dicarboxylic acid

C: 57-13-6
urea

D HgS: HgS

...Expand

: 64-17-5
ethanol

: 88-99-3
benzene-1,2-dicarboxylic acid

: 2306-33-4
monoethyl phthalate

Conditions

Conditions	Yield
With poly(ethylene glycol) 1000 based dicationic acidic ionic liquid In toluene at 80℃; for 0.833333h; Ionic liquid;	99 %Chromat.

: 64139-21-5
Diethyl 4-hydroxyphthalate

A: 2306-33-4
monoethyl phthalate

B: 2-(ethoxycarbonyl)-5-hydroxybenzoic acid

Conditions

Conditions	Yield
With sodium hydroxide In water pH=10; Catalytic behavior; Reagent/catalyst; pH-value; UV-irradiation;

: 2306-33-4
monoethyl phthalate

: 22103-82-8
phthalic monoacid monoethyl ester chloride

Conditions

Conditions	Yield
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 4h;	100%
With thionyl chloride at 24℃; for 4h;	66%
With phosphorus trichloride; benzene

: 539-82-2
ethyl n-valerate

: 2306-33-4
monoethyl phthalate

: 2-[(2-ethoxycarbonyl)pentanoyl]benzoic acid

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 0 - 100℃;	93.8%

: 2306-33-4
monoethyl phthalate

: 536-38-9
4-chlorobenzoylmethyl bromide

: o-phthalic acid 1-[2-(4-chlorophenyl)-2-oxoethyl] ester 2-ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	77%

: 2306-33-4
monoethyl phthalate

: 1835-02-5
2-Bromo-1-(3,4-dimethoxyphenyl)ethanone

: o-phthalic acid 1-[2-(3,4-dimethoxyphenyl)-2-oxoethyl] ester 2-ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	76%

: 2306-33-4
monoethyl phthalate

: 139029-97-3
2-Hydroperoxycarbonyl-benzoic acid ethyl ester

Conditions

Conditions	Yield
With sulfuric acid; dihydrogen peroxide at 10℃; for 1h;	72%

: 78-83-1
2-methyl-propan-1-ol

: 2306-33-4
monoethyl phthalate

: 30833-53-5
phtalic acid mono-iso-butyl ester

Conditions

Conditions	Yield
at 120℃;	69%

: 2306-33-4
monoethyl phthalate

: 2631-72-3
2,4-dichlorophenacyl bromide

: o-phthalic acid 1-[2-(2,4-dichlorophenyl)-2-oxoethyl] ester 2-ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	68%

: 2306-33-4
monoethyl phthalate

: 403-29-2
2-bromo-4'-fluoroacetophenone

: o-phthalic acid 1-ethyl ester 2-[2-(4-fluorophenyl)-2-oxoethyl] ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	68%

: 2306-33-4
monoethyl phthalate

: 53631-13-3
2-bromo-3',5'-dichloroacetophenone

: o-phthalic acid 1-[2-(3,5-dichlorophenyl)-2-oxoethyl] ester 2-ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	64%

: 2306-33-4
monoethyl phthalate

: 619-41-0
4-(bromoacetyl)toluene

: o-phthalic acid 1-ethyl ester 2-(2-oxo-2-p-tolylethyl) ester

Conditions

Conditions	Yield
With triethylamine In acetone for 2h; Heating;	63%

: 2306-33-4
monoethyl phthalate

: 22019-49-4
2-bromo-1-(4-chloro-3-nitrophenyl)ethanone

: o-phthalic acid 1-[2-(4-chloro-3-nitrophenyl)-2-oxoethyl] ester 2-ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	62%

: 2306-33-4
monoethyl phthalate

: 70-11-1
α-bromoacetophenone

: 914930-45-3
o-phthalic acid 1-ethyl ester 2-(2-oxo-2-phenylethyl) ester

Conditions

Conditions	Yield
With triethylamine In acetone for 3h; Heating;	58%

: 34672-84-9
1-methoxy-2,2,6,6-tetramethylpiperidine

: 2306-33-4
monoethyl phthalate

: 34006-77-4
ethyl methyl phthalate

Conditions

Conditions	Yield
With 2,6-di-tert-butyl-pyridine In acetonitrile at 21 - 25℃; for 18h; Electrochemical reaction;	57%

: 2306-33-4
monoethyl phthalate

: 99-81-0
4-Nitrophenacyl bromide

: o-phthalic acid 1-ethyl ester 2-[2-(4-nitrophenyl)-2-oxoethyl] ester

Conditions

Conditions	Yield
With triethylamine In acetone for 1.5h; Heating;	56%

: 2306-33-4
monoethyl phthalate

: 37148-47-3
1-(4-amino-3,5-dichlorophenyl)-2-bromoethan-1-one

: o-phthalic acid 1-[2-(4-amino-3,5-dichlorophenyl)-2-oxoethyl] ester 2-ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetone for 0.5h; Heating;	52%

: 2306-33-4
monoethyl phthalate

A: 102081-79-8
diethyl 2,2'-[carbonylbis(azanediyl)]dibenzoate

B: ethyl 2-[(azidocarbonyl)amino]benzoate

Conditions

Conditions	Yield
With diphenyl phosphoryl azide; triethylamine In toluene for 2h; Reflux;	A 30% B 28%

: 67-56-1
methanol

: 2306-33-4
monoethyl phthalate

: 34006-77-4
ethyl methyl phthalate

: 109-65-9
1-bromo-butane

: 2306-33-4
monoethyl phthalate

: 7299-93-6
phtalic acid ethyl-n-butyl ester

: 7299-41-4, 148552-65-2
β-terpineol

: 2306-33-4
monoethyl phthalate

: phthalic acid ethyl ester-(trans-p-menth-8-en-1-yl ester)

Conditions

Conditions	Yield
With thionyl chloride

: 2306-33-4
monoethyl phthalate

: 87-41-2
2-benzofuran-1(3H)-one

Conditions

Conditions	Yield
With tetrahydrofuran; lithium aluminium tetrahydride
With tetrahydrofuran; lithium aluminium tetrahydride; diethyl ether

Monoethyl phthalate Chemical Properties

Molecule structure of Monoethyl phthalate (CAS NO.2306-33-4) :

IUPAC Name: 2-ethoxycarbonylbenzoic acid
Molecular Weight: 194.184 g/mol
Molecular Formula: C₁₀H₁₀O₄
Density: 1.241 g/cm³
Boiling Point: 339.6 °C at 760 mmHg
Flash Point: 135.3 °C
Index of Refraction: 1.547
Molar Refractivity: 49.58 cm³
Molar Volume: 156.3 cm³
Polarizability: 19.65*10^-24 cm³
Surface Tension: 49.1 dyne/cm
Enthalpy of Vaporization: 61.54 kJ/mol
Vapour Pressure: 3.53E-05 mmHg at 25 °C
XLogP3: 1.8
H-Bond Donor: 1
H-Bond Acceptor: 4
Rotatable Bond Count: 4
Exact Mass: 194.057909
MonoIsotopic Mass: 194.057909
Topological Polar Surface Area: 63.6
Heavy Atom Count: 14
Complexity: 224
Canonical SMILES: CCOC(=O)C1=CC=CC=C1C(=O)O
InChI: InChI=1S/C10H10O4/c1-2-14-10(13)8-6-4-3-5-7(8)9(11)12/h3-6H,2H2,1H3,(H,11,12)
InChIKey of Monoethyl phthalate (CAS NO.2306-33-4) : YWWHKOHZGJFMIE-UHFFFAOYSA-N

Monoethyl phthalate Toxicity Data With Reference

ipr-mus LD50:700 mg/kg

CHDDAT Comptes Rendus Hebdomadaires des Seances de lAcademie des Sciences, Serie D. 273 (1971),2165.

Monoethyl phthalate Safety Profile

Moderately toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating vapors.

Monoethyl phthalate Specification

Monoethyl phthalate (CAS NO.2306-33-4) is also called 1,2-Benzenecarboxylic acid, monoethyl ester ; 4-09-00-03171 (Beilstein Handbook Reference) ; AI3-02249 ; BRN 1956404 ; 1,2-Benzenedicarboxylic acid, monoethyl ester ; Phthalic acid, monoethyl ester .

Product Name

ETHYL PHTHALATE MONO

Synthetic route

Monoethyl phthalate Chemical Properties

Monoethyl phthalate Toxicity Data With Reference

Monoethyl phthalate Safety Profile

Monoethyl phthalate Specification

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