N-Butyl-benzenesulfonamide supplier

Name
N-n-Butylbenzenesulfonamide
EINECS 222-823-6
CAS No. 3622-84-2
Article Data33
CAS DataBase
Density 1.125 g/cm³
Solubility 450mg/L at 20℃
Melting Point -30oC
Formula C₁₀H₁₅NO₂S
Boiling Point 326.7 °C at 760 mmHg
Molecular Weight 213.301
Flash Point 151.4 °C
Transport Information
Appearance COA
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms AK 551;BBSA;BM 4 (sulfonamide);Cetamoll BMB;Dellatol BBS;N-(n-Butyl)benzenesulfonamide;NSC 3536;PlasthallBSA;Plastomoll BMB;Topcizer 7;Uniplex 214;BM 4;N-Butyl-benzenesulfonamide;
PSA 54.55000
LogP 3.23670

Synthetic route

: 109-73-9
N-butylamine

: 98-09-9
benzenesulfonyl chloride

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With sodium hydroxide In water at 25℃; pH=10.2;	99%
With sodium hydroxide In water at 20℃; for 1.5h; Reagent/catalyst;	99%
In dichloromethane at 0 - 20℃; for 0.25h;	98%

: 109-73-9
N-butylamine

microgel-supported-PhSO2: microgel-supported-PhSO2

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
In tetrahydrofuran at 25℃; for 13.5h; Inert atmosphere;	97.6%

: 6829-66-9
N-butylbenzenesulfinamide

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 0.5h;	93%

: C24H32N3O3S(1+)*F6P(1-)

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With trifluoroacetic acid for 10h;	91%

: 873-55-2
sodium benzenesulfonate

: 109-73-9
N-butylamine

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With iodine In 1,2-dichloro-ethane at 25℃; for 12h;	90%

: 108-98-5
thiophenol

: 109-73-9
N-butylamine

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With hydrogenchloride; tetramethylammonium tetrafluoroborate In water; acetonitrile at 20℃; for 0.0833333h; Electrochemical reaction;	81%

: 98-10-2
benzenesulfonamide

: 142-96-1
dibutyl ether

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With titanium tetrachloride In 1,1,2,2-tetrachloroethane at 120℃; for 48h; sealed tube;	80%

: 5535-48-8
PVS

: 109-73-9
N-butylamine

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
Stage #1: N-butylamine With N-Bromosuccinimide; tetraethylammoniumcyanide In dichloromethane Stage #2: PVS In dichloromethane at 20℃; for 1h;	72%

: 1212-08-4
S-Phenyl benzenethiosulfonate

: 109-73-9
N-butylamine

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With N-Bromosuccinimide; caesium carbonate In ethanol at 80℃; for 16h; Sealed tube;	66%

: 369-57-3
benzenediazonium tetrafluoroborate

: 109-73-9
N-butylamine

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
Stage #1: benzenediazonium tetrafluoroborate With 1,4-diazabicyclo[2.2.2]octane-triethylenediamine-bis(sulfur dioxide); benzotriazol-1-ol In 1,2-dichloro-ethane at 60℃; for 1h; Inert atmosphere; Stage #2: N-butylamine With N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃; for 2h; Inert atmosphere;	64%

: 109-73-9
N-butylamine

: 80-17-1
benzenesufonyl hydrazide

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With copper(ll) bromide In acetonitrile at 50℃; for 12h;	49%

: 3858-78-4
n-butylamine hydrochloride

: 80-17-1
benzenesufonyl hydrazide

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With sodium carbonate; copper(ll) bromide In acetonitrile at 50℃; for 12h;	46%

: 109-73-9
N-butylamine

: 98-09-9
benzenesulfonyl chloride

A: 3622-84-2
N-butylbenzenesulfonamide

B: 54563-71-2
bis-benzenesulfonyl-butyl-amine

...Expand

: 23837-25-4
N-(phenylthio)-N-(normal-butyl)amine

: 71-43-2
benzene

A: 1212-08-4
S-Phenyl benzenethiosulfonate

B: 92-52-4
biphenyl

C: 6829-66-9
N-butylbenzenesulfinamide

D: 3622-84-2
N-butylbenzenesulfonamide

E: 882-33-7
diphenyldisulfane

Conditions

Conditions	Yield
With norborn-2-ene; oxygen; thiamine diphosphate for 0.416667h; Product distribution; Irradiation; photooxidation of sulfenamides in benzene solution; AIBN reaction; chemical oxidation with endoperoxide; intermediate formation of iminopersulfinic acids; quenching of singlet oxygen, kT; epoxidizing of norbornene;

...Expand

: 109-73-9
N-butylamine

: 98-09-9
benzenesulfonyl chloride

A: 3622-84-2
N-butylbenzenesulfonamide

B dibenzenesulfonylbutylamine: dibenzenesulfonylbutylamine

Conditions

Conditions	Yield
With alkali

...Expand

: 98-11-3
benzenesulfonic acid

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 100 percent / Cl3CCN; PPh3 / CH2Cl2 / 1 h / Heating 2: 83 percent / 4-picoline / CH2Cl2 / 1 h / 20 °C View Scheme

: 1190977-80-0
N-butyl-N-(2,2,2-trichloroacetyl)benzenesulfonamide

A: 1190977-91-3
N-butyl-2,2-dichloro-2-phenylacetamide

B: 1190977-86-6
N-butyl-2,2-dichloro-N-(phenylsulfonyl)acetamide

C: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With dichloromethane; N,N,N',N'',N'''-pentamethyldiethylenetriamine; copper(I) bromide at 20℃; for 24h; Inert atmosphere;

...Expand

: 1190977-86-6
N-butyl-2,2-dichloro-N-(phenylsulfonyl)acetamide

A: 72310-00-0
C12H16ClNO3S

B: 91802-54-9
α-Chlor-phenylessigsaeure-butylamid

C: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With dichloromethane; N,N,N',N'',N'''-pentamethyldiethylenetriamine; copper(l) chloride for 4h; Reflux; Inert atmosphere;

...Expand

: 1197341-37-9
C12H16BrNO3S

A: 1197341-39-1
C12H17NO3S

B: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With dichloromethane; N,N,N',N'',N'''-pentamethyldiethylenetriamine; copper(I) bromide for 4h; Reflux; Inert atmosphere;

: 1197341-38-0
C14H20BrNO3S

A: N-butyl-2,2-dimethyl-2-phenylacetamide

B: 1197341-40-4
C14H21NO3S

C: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
With dichloromethane; N,N,N',N'',N'''-pentamethyldiethylenetriamine; copper(I) bromide at 20℃; for 24h; Inert atmosphere;

...Expand

: 670-98-4
methyl benzenesulfinate

: 3622-84-2
N-butylbenzenesulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 22 h / Sonication; Neat (no solvent) 2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.5 h / 20 °C View Scheme

: 3622-84-2
N-butylbenzenesulfonamide

: 247018-51-5
4-t-butylphenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate

: 1198294-00-6
N-butyl-N-(4-tert-butylphenyl)benzenesulfonamide

Conditions

Conditions	Yield
With bis(η3-allyl-μ-chloropalladium(II)); bis(3,5-bis(trifluoromethyl)phenyl)(2’,4’,6’-triisopropyl-3,6-dimethoxy-[1,1’-biphenyl]-2-yl)phosphine; potassium carbonate In toluene at 110℃; for 17h; Inert atmosphere; Molecular sieve;	95%

: 3622-84-2
N-butylbenzenesulfonamide

: 106-95-6
allyl bromide

: C13H19NO2S

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 25℃;	90%

: 49640-96-2
diethyl (hydroxy(4-methoxyphenyl)methyl)phosphonate

: 3622-84-2
N-butylbenzenesulfonamide

: (±)-diethyl (N-butylphenylsulfonamido)(4-methoxyphenyl)methylphosphonate

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In 1,4-dioxane at 20℃; for 12h;	88%

: 3622-84-2
N-butylbenzenesulfonamide

: 541-41-3
chloroformic acid ethyl ester

: 51920-54-8
ethyl N-(benzenesulfonyl) N-(n-butyl) carbamate

Conditions

Conditions	Yield
With sodium hydroxide In triethylamine	85.2%

: 79-36-7
dichloroacethyl chloride

: 3622-84-2
N-butylbenzenesulfonamide

: 1190977-86-6
N-butyl-2,2-dichloro-N-(phenylsulfonyl)acetamide

Conditions

Conditions	Yield
Stage #1: N-butylbenzenesulfonamide With n-butyllithium In tetrahydrofuran at -78℃; for 0.583333h; Inert atmosphere; Stage #2: dichloroacethyl chloride In tetrahydrofuran at -78 - 20℃; for 24h; Inert atmosphere;	84%

: 3622-84-2
N-butylbenzenesulfonamide

: 76-02-8
Trichloroacetyl chloride

: 1190977-80-0
N-butyl-N-(2,2,2-trichloroacetyl)benzenesulfonamide

Conditions

Conditions	Yield
Stage #1: N-butylbenzenesulfonamide With n-butyllithium In tetrahydrofuran at -78℃; for 0.583333h; Inert atmosphere; Stage #2: trifluoroacetyl chloride In tetrahydrofuran at -78 - 20℃; for 24h; Inert atmosphere;	82%

: 3622-84-2
N-butylbenzenesulfonamide

: 79158-10-4
(1-hydroxy-3-phenyl-allyl)-phosphonic acid diethyl ester

: (E)-diethyl [3-(N-butylphenylsulfonamido)-3-phenylprop-1-enyl]phosphonate

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In 1,4-dioxane at 20℃; for 12h; stereoselective reaction;	82%

: 22118-09-8
2-bromoacetyl chloride

: 3622-84-2
N-butylbenzenesulfonamide

: 1197341-37-9
C12H16BrNO3S

Conditions

Conditions	Yield
Stage #1: N-butylbenzenesulfonamide With n-butyllithium In tetrahydrofuran at -78℃; for 0.583333h; Inert atmosphere; Stage #2: 2-bromoacetyl chloride In tetrahydrofuran at -78 - 20℃; for 24h; Inert atmosphere;	72%

: 3622-84-2
N-butylbenzenesulfonamide

: 93-55-0
1-phenyl-propan-1-one

: (E)-N-butyl-N-(3-oxo-3-phenylprop-1-en-1-yl)benzenesulfonamide

Conditions

Conditions	Yield
With dmap; copper(I) thiophene-2-carboxylate; oxygen; 4-methoxy-2,2,6,6-tetramethylpiperidin-1-oxyl radical In dimethyl sulfoxide at 110℃; for 24h; Schlenk technique;	67%

: 3622-84-2
N-butylbenzenesulfonamide

: 3433-80-5
1-Bromo-2-bromomethyl-benzene

: 6-butyl-6,7-dihydrodibenzo[d,f][1,2]thiazepine 5,5-dioxide

Conditions

Conditions	Yield
With palladium diacetate; caesium carbonate; triphenylphosphine In 1,4-dioxane at 110℃; for 18h; Inert atmosphere; Sealed tube;	64%

: 20769-85-1
2-bromoisobutyric acid bromide

: 3622-84-2
N-butylbenzenesulfonamide

: 1197341-38-0
C14H20BrNO3S

Conditions

Conditions	Yield
Stage #1: N-butylbenzenesulfonamide With n-butyllithium In tetrahydrofuran at -78℃; for 0.583333h; Inert atmosphere; Stage #2: 2-bromoisobutyric acid bromide In tetrahydrofuran at -78 - 20℃; Inert atmosphere;	62%

: 3622-84-2
N-butylbenzenesulfonamide

: 1448522-62-0
N-butyl-2-hydroxybenzenesulfonamide

Conditions

Conditions	Yield
With dipotassium peroxodisulfate; palladium diacetate; trifluoroacetic acid; trifluoroacetic anhydride at 60℃; for 20h; Sealed tube; regioselective reaction;	54%

: 3622-84-2
N-butylbenzenesulfonamide

: 1311931-02-8
N-butyl-2-chlorobenzenesulfonamide

Conditions

Conditions	Yield
With N-chloro-succinimide; trifluorormethanesulfonic acid; palladium diacetate; N-fluoropyridinium triflate In 1,2-dichloro-ethane at 60℃; for 4h; Sealed tube; regioselective reaction;	49%

: 542-69-8
1-iodo-butane

: 3622-84-2
N-butylbenzenesulfonamide

: 5339-59-3
N,N-dibutylbenzenesulfonamide

Conditions

Conditions	Yield
With potassium hydroxide; ethanol

: 3622-84-2
N-butylbenzenesulfonamide

: 79506-19-7
N-butyl-N-nitro-benzenesulfonamide

Conditions

Conditions	Yield
With nitric acid

: 3622-84-2
N-butylbenzenesulfonamide

: 609-65-4
o-chlorobenzoyl chloride

: 66897-47-0
N-Butyl-N-(2-chloro-benzoyl)-benzenesulfonamide

Conditions

Conditions	Yield
(i) NaH, DMF, (ii) /BRN= 386435/; Multistep reaction;

N-Butyl-benzenesulfonamide Chemical Properties

IUPAC Name:N-butylbenzenesulfonamide
Molecular Formula:C₁₀H₁₅NO₂S
Molecular Weight:213.296600 g/mol
Appearance:clear oily liquid
Melting Point:-30 °C
Boiling Point:314 °C(lit.)
Flash Point:>230 °F
density:1.15 g/mL at 25 °C(lit.)
vapor pressure:0.35 mm Hg ( 150 °C)
refractive index:n20/D 1.525(lit.)
EINECS:222-823-6
Synonyms of N-BUTYLBENZENESULFONAMIDE(3622-84-2):
TIMTEC-BB SBB008484;RIT-CIZER NO 7;N-N-BUTYLBENZENESULFONAMIDE;N-N-BUTYLBENZENESULPHONAMIDE;N-BENZENESULFONYL-N-BUTYLAMINE;N-BUTYLBENZENESULFONAMIDE;(butyl)benzenesulfonamide;Benzenesulfonamide,N-butyl-;N-n-Butylbenzenesulfonamide
Categories of N-BUTYLBENZENESULFONAMIDE(3622-84-2):
Camphor, etc. (Plasticizer);Functional Materials;Plasticizer;Organic Building Blocks;Sulfonamides/Sulfinamides;Sulfur Compounds

N-Butyl-benzenesulfonamide Uses

N-BUTYLBENZENESULFONAMIDE(3622-84-2) is used as a plasticizer in polyamide and cellulose resin.

N-Butyl-benzenesulfonamide Toxicity Data With Reference

1.	orl-rat LD50:2050 mg/kg	TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Sciences. 15 (1979),110.
2.	orl-mus LD50:2500 mg/kg	TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Sciences. 15 (1979),110.
3.	orl-uns LD50:2900 mg/kg	GISAAA Gigiena i Sanitariya. 39 (4)(1974),86.

N-Butyl-benzenesulfonamide Consensus Reports

Reported in EPA TSCA Inventory.

N-Butyl-benzenesulfonamide Safety Profile

Safety Information of N-BUTYLBENZENESULFONAMIDE(3622-84-2):
Hazard Codes:Xi
Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:Wear suitable protective clothing
WGK Germany:2
RTECS:DB1283000
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NO_x and SO_x.

Product Name

N-n-Butylbenzenesulfonamide

Synthetic route

N-Butyl-benzenesulfonamide Chemical Properties

N-Butyl-benzenesulfonamide Uses

N-Butyl-benzenesulfonamide Toxicity Data With Reference

N-Butyl-benzenesulfonamide Consensus Reports

N-Butyl-benzenesulfonamide Safety Profile

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