Product Name

  • Name

    N,N'-Dimethyl-1,2-ethanediamine

  • EINECS 203-793-3
  • CAS No. 110-70-3
  • Article Data35
  • CAS DataBase
  • Density 0.785 g/cm3
  • Solubility Solubility in water
  • Melting Point 1.63°C (estimate)
  • Formula C4H12N2
  • Boiling Point 120 °C at 760 mmHg
  • Molecular Weight 88.1527
  • Flash Point 83 °F
  • Transport Information UN 2734 8/PG 2
  • Appearance colorless liquid
  • Safety 26-36/37/39-45-16
  • Risk Codes 10-34-20/21/22
  • Molecular Structure Molecular Structure of 110-70-3 (N,N'-Dimethyl-1,2-ethanediamine)
  • Hazard Symbols CorrosiveC
  • Synonyms 1,2-Ethanediamine,N,N'-dimethyl- (9CI);Ethylenediamine, N,N'-dimethyl- (6CI,7CI,8CI);(Methyl)[2-(methylamino)ethyl]amine;1,2-Bis(methylamino)ethane;2,5-Diazahexane;N,N'-Dimethyl-1,2-diaminoethane;N,N'-Dimethyl-1,2-ethanediamine;N,N'-Dimethyl-1,2-ethylenediamine;N,N'-Dimethyldiaminoethane;N-Methyl-N-[2-(methylamino)ethyl]amine;Symmetrical dimethylethylenediamine;sym-Dimethylethylenediamine;
  • PSA 24.06000
  • LogP 0.20700

Synthetic route

1-methylhydantoin
6843-45-4

1-methylhydantoin

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 72h; Heating; Argon;85%
1,3-dimethyl-2-imidazolidinone
80-73-9

1,3-dimethyl-2-imidazolidinone

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With potassium hydroxide at 140℃; Reagent/catalyst; Large scale;85%
C8H24CuN4(2+)*2ClO4(1-)

C8H24CuN4(2+)*2ClO4(1-)

A

1,2-bismethylnitrosaminoethane
13256-12-7

1,2-bismethylnitrosaminoethane

B

2-Nitroso-2,5-diazahexan
29104-67-4

2-Nitroso-2,5-diazahexan

C

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
Stage #1: C8H24CuN4(2+)*2ClO4(1-) With nitrogen(II) oxide; acetonitrile for 0.166667h;
Stage #2: In acetonitrile; benzene for 1h;
Stage #3: With sodium sulfide In water; acetonitrile; benzene for 0.5h; Saturated solution;
A 17%
B 16%
C 65%
N,N′-(ethane-1,2-diyl)bis(N,4-dimethylbenzenesulfonamide)
66821-82-7

N,N′-(ethane-1,2-diyl)bis(N,4-dimethylbenzenesulfonamide)

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With sulfuric acid In water at 90 - 100℃;48%
ethylene glycol
107-21-1

ethylene glycol

methylamine
74-89-5

methylamine

A

N,N'-dimethylpiperazine
106-58-1

N,N'-dimethylpiperazine

B

(2-hydroxyethyl)(methyl)amine
109-83-1

(2-hydroxyethyl)(methyl)amine

C

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; tris(triphenylphosphine)ruthenium(II) chloride at 130℃; Product distribution; Mechanism; other primary amines, other temperatures, other catalyst;A 33%
B 4%
C 44%
N,N'-dimethylethane-1,2-diamine dihydrochloride
5752-40-9, 68696-81-1, 117880-00-9

N,N'-dimethylethane-1,2-diamine dihydrochloride

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With ammonia; sodium hydride for 4h; Schlenk technique; Cooling with acetone-dry ice; Reflux;44%
ethylene dibromide
106-93-4

ethylene dibromide

methylamine
74-89-5

methylamine

A

N,N'-dimethylpiperazine
106-58-1

N,N'-dimethylpiperazine

B

N,N',N''-trimethyldiethylenetriamine
105-84-0

N,N',N''-trimethyldiethylenetriamine

C

1,4,7,10-tetramethyl-1,4,7,10-tetraazadecane
105-78-2

1,4,7,10-tetramethyl-1,4,7,10-tetraazadecane

D

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
In water at 20℃; for 336000h;A 9%
B 2%
C 1%
D 10%
(2-hydroxyethyl)(methyl)amine
109-83-1

(2-hydroxyethyl)(methyl)amine

A

1-methyl-piperazine
109-01-3

1-methyl-piperazine

B

N,N'-dimethylpiperazine
106-58-1

N,N'-dimethylpiperazine

C

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
at 250℃; Reaktion des Hydrochlorids;
N,N'-dimethyl-N,N'-bis-(4-nitroso-phenyl)-ethylenediamine
4963-32-0

N,N'-dimethyl-N,N'-bis-(4-nitroso-phenyl)-ethylenediamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With sodium hydrogensulfite
1,4-dimethyl-1,4-diazabicyclo[2.2.2]octane-1,4-diium hydroxide
14960-53-3

1,4-dimethyl-1,4-diazabicyclo[2.2.2]octane-1,4-diium hydroxide

A

N,N'-dimethylpiperazine
106-58-1

N,N'-dimethylpiperazine

B

acetaldehyde
75-07-0

acetaldehyde

C

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
at 120℃;
N-methyl-2-chloroethylamine
32315-92-7

N-methyl-2-chloroethylamine

methylamine
74-89-5

methylamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

methylamine
74-89-5

methylamine

A

N,N',N''-trimethyldiethylenetriamine
105-84-0

N,N',N''-trimethyldiethylenetriamine

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

ethylene dibromide
106-93-4

ethylene dibromide

methylamine
74-89-5

methylamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

C18H22N2(2+)*2CH3O4S(1-)
75189-90-1

C18H22N2(2+)*2CH3O4S(1-)

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With sulfuric acid In water for 1h; Heating; Yield given;
2-(p-dimethylaminostyryl)-N,N'-dimethyl-1,3-imidazolidine
74401-95-9

2-(p-dimethylaminostyryl)-N,N'-dimethyl-1,3-imidazolidine

A

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

B

p-dimethylaminocinnamaldehyde
6203-18-5

p-dimethylaminocinnamaldehyde

Conditions
ConditionsYield
With water at 30℃; Mechanism; Rate constant; pH dependence of rate constant, intermediate formation of cationic Schiff base;
1,3-dimethyl-2-imidazolidinone
80-73-9

1,3-dimethyl-2-imidazolidinone

A

sodium formate
141-53-7

sodium formate

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With sodium hydroxide In water at 25℃; Rate constant; hydrolytic decomposition;
1,2-bis-<(2-carboxy-benzenesulfonyl)-methyl-amino>-ethane

1,2-bis-<(2-carboxy-benzenesulfonyl)-methyl-amino>-ethane

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With hydrogenchloride
ethylene dibromide
106-93-4

ethylene dibromide

liquid methylamine

liquid methylamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

N.N'-dimethyl-N.N'-bis--ethylenediamine

N.N'-dimethyl-N.N'-bis--ethylenediamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With hydrogenchloride
N,N'-di-p-toluenesulfonyl-N,N'-dimethyl-ethylenediamine

N,N'-di-p-toluenesulfonyl-N,N'-dimethyl-ethylenediamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With sulfuric acid
methanol
67-56-1

methanol

ethylenediamine
107-15-3

ethylenediamine

A

N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

B

N-methyl-ethane-1,2-diamine
109-81-9

N-methyl-ethane-1,2-diamine

C

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With Cs-P-Si at 300℃; under 61504.9 Torr;
N.N'-di-p-toluenesulfonyl-N.N'-dimethyl-ethylenediamine

N.N'-di-p-toluenesulfonyl-N.N'-dimethyl-ethylenediamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With sulfuric acid at 150℃;
With hydrogenchloride at 150℃;
(CH3)NH(CH2)2N(CH3)CH2CH(P(C6H5)2)2Cr(CO)4

(CH3)NH(CH2)2N(CH3)CH2CH(P(C6H5)2)2Cr(CO)4

A

(CO)4Cr(PPh2C(=CH2)PPh2)
85683-25-6

(CO)4Cr(PPh2C(=CH2)PPh2)

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
In methanol dissoziation in MeOH at 50°C;
(CH3)NH(CH2)2N(CH3)CH2CH(P(C6H5)2)2W(CO)4

(CH3)NH(CH2)2N(CH3)CH2CH(P(C6H5)2)2W(CO)4

A

(CO)4W(PPh2C(=CH2)PPh2)
84534-91-8

(CO)4W(PPh2C(=CH2)PPh2)

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
In methanol dissoziation in MeOH at 50°C;
1,3-dimethyl-2-phenylimidazolidine
23229-37-0

1,3-dimethyl-2-phenylimidazolidine

A

benzaldehyde
100-52-7

benzaldehyde

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With water at 20℃; for 49h; pH=6.5 - 7.0; Reactivity; Aqueous phosphate buffer;
In tetrahydrofuran-d8 for 240h; Equilibrium constant; Kinetics; phosphate buffer in D2O;
methanol
67-56-1

methanol

Reaxys ID: 11370757

Reaxys ID: 11370757

ethylenediamine
107-15-3

ethylenediamine

A

N,N,N,N,-tetramethylethylenediamine
110-18-9

N,N,N,N,-tetramethylethylenediamine

B

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

C

N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

D

N-methyl-ethane-1,2-diamine
109-81-9

N-methyl-ethane-1,2-diamine

E

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
Stage #1: With hydrogen at 200℃; for 3h;
Stage #2: methanol; ethylenediamine With hydrogen at 200℃; under 7500.75 Torr; for 8h; Product distribution / selectivity;
propylamine
107-10-8

propylamine

N,N'-dimethyl-2-(2-hydroxylphenyl)-imidazolidine

N,N'-dimethyl-2-(2-hydroxylphenyl)-imidazolidine

A

N-n-propylsalicylideneamine
32382-63-1, 146305-09-1

N-n-propylsalicylideneamine

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
In chloroform-d1 Equilibrium constant;
D-glucose
50-99-7

D-glucose

methylamine
74-89-5

methylamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With 5 wt% ruthenium/carbon; hydrogen In water at 124.84℃; under 56255.6 Torr; for 1h;43 %Spectr.
D-glucose
50-99-7

D-glucose

methylamine
74-89-5

methylamine

A

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8

1-deoxy-1-(methylamino)-D-glucitol

B

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
With 5 wt% ruthenium/carbon; hydrogen In water at 124.84℃; under 56255.6 Torr; for 1h;
furfural
98-01-1

furfural

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-(furan-2-yl)-1,3-dimethylimidazolidine
104208-14-2

2-(furan-2-yl)-1,3-dimethylimidazolidine

Conditions
ConditionsYield
With copper(II) bis(trifluoromethanesulfonate) In water at 20℃; for 0.0333333h;100%
In benzene for 12h; Heating;94%
In toluene for 2h; Heating / reflux;85%
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,3-dimethyl-2-(thiophen-2-yl)imidazolidine
104208-13-1

1,3-dimethyl-2-(thiophen-2-yl)imidazolidine

Conditions
ConditionsYield
In toluene at 0℃; for 3h; Heating / reflux;100%
In benzene for 12h; Heating;87%
In benzene for 12h; Heating;80%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

4-(1,3-dimethylimidazolidin-2-yl)phenol
83521-93-1

4-(1,3-dimethylimidazolidin-2-yl)phenol

Conditions
ConditionsYield
In toluene for 3h; Reflux;100%
In benzene for 20h; Heating;25%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

tert-butyl N-methyl-N-<2-(methylamino)ethyl>carbamate
112257-19-9

tert-butyl N-methyl-N-<2-(methylamino)ethyl>carbamate

Conditions
ConditionsYield
With trifluoroacetic acid In tetrahydrofuran at 20℃; for 22h;100%
In dichloromethane for 4h; Ambient temperature;90%
In dichloromethane at 20℃;89%
piperidin-1-yl-phosphonic acid dichloride
1498-56-2

piperidin-1-yl-phosphonic acid dichloride

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,3-dimethyl-2-piperidinyl-1,3,2-diazaphospholidine-2-oxide
219556-12-4

1,3-dimethyl-2-piperidinyl-1,3,2-diazaphospholidine-2-oxide

Conditions
ConditionsYield
With triethylamine In dichloromethane for 40h; Heating;100%
With triethylamine In dichloromethane for 40h; Heating;99%
With triethylamine In benzene at 20℃; for 2h;90%
2-hydroxy-5-methylbenzaldehyde
613-84-3

2-hydroxy-5-methylbenzaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-(2-hydroxy-5-methylphenyl)-1,3-dimethylimidazolidine
234765-65-2

2-(2-hydroxy-5-methylphenyl)-1,3-dimethylimidazolidine

Conditions
ConditionsYield
With magnesium sulfate In ethanol at 20℃; for 16h; Condensation;100%
piperonal
120-57-0

piperonal

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-(benzo-1,3-dioxol-5-yl)-1,3-dimethylimidazolidine
302968-94-1

2-(benzo-1,3-dioxol-5-yl)-1,3-dimethylimidazolidine

Conditions
ConditionsYield
In toluene for 4h; Reflux;100%
In toluene for 5h; Condensation; cyclization; Heating;79%
2,2'-Bipyridine-4,4'-dicarboxylic acid
6813-38-3

2,2'-Bipyridine-4,4'-dicarboxylic acid

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

[2,2']bipyridinyl-4,4'-dicarboxylic acid bis-[methyl-(2-methylamino-ethyl)-amide]

[2,2']bipyridinyl-4,4'-dicarboxylic acid bis-[methyl-(2-methylamino-ethyl)-amide]

Conditions
ConditionsYield
Stage #1: 2,2'-Bipyridine-4,4'-dicarboxylic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 60℃;
Stage #2: N,N`-dimethylethylenediamine In tetrahydrofuran at 20℃;
100%
4'-methyl-2,2'-bipyridine-4-carboxylic acid
103946-54-9

4'-methyl-2,2'-bipyridine-4-carboxylic acid

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

4'-methyl-[2,2']bipyridinyl-4-carboxylic acid methyl-(2-methylamino-ethyl)-amide
524957-05-9

4'-methyl-[2,2']bipyridinyl-4-carboxylic acid methyl-(2-methylamino-ethyl)-amide

Conditions
ConditionsYield
Stage #1: 4'-methyl-2,2'-bipyridine-4-carboxylic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 60℃;
Stage #2: N,N`-dimethylethylenediamine In tetrahydrofuran at 20℃;
100%
(R)-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethyl acetate

(R)-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethyl acetate

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

(S)-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethyl-N,N'-dimethylethylenediamine

(S)-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethyl-N,N'-dimethylethylenediamine

Conditions
ConditionsYield
In methanol Heating / reflux;100%
bromo-(4-nitrophenyl)acetic acid methyl ester
85259-33-2

bromo-(4-nitrophenyl)acetic acid methyl ester

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,4-dimethyl-3-(4-nitrophenyl)piperazin-2-one
1133433-91-6

1,4-dimethyl-3-(4-nitrophenyl)piperazin-2-one

Conditions
ConditionsYield
In ethanol at 0 - 25℃;100%
In ethanol at 20℃; for 1h;89%
In ethanol at 20℃; for 1h; Inert atmosphere;89%
In ethanol at 0 - 20℃; for 2h; Inert atmosphere;56%
Z-Lys(Boc)-OH
2389-60-8

Z-Lys(Boc)-OH

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Benzyl-((1S)-5-((tert-butoxycarbonyl)amino)-1-(methyl(2-(methylamino)ethyl)carbamoyl)pentyl)carbamate
952571-77-6

Benzyl-((1S)-5-((tert-butoxycarbonyl)amino)-1-(methyl(2-(methylamino)ethyl)carbamoyl)pentyl)carbamate

Conditions
ConditionsYield
In tetrahydrofuran at 20℃;100%
2-(t-butyldimethylsilanyloxy)-4,5-methylenedioxybenzaldehyde
1192469-71-8

2-(t-butyldimethylsilanyloxy)-4,5-methylenedioxybenzaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-[6-(t-butyldimethylsilanyloxy)benzo-1,3-dioxol-5-yl]-1,3-dimethylimidazolidine
1192469-72-9

2-[6-(t-butyldimethylsilanyloxy)benzo-1,3-dioxol-5-yl]-1,3-dimethylimidazolidine

Conditions
ConditionsYield
In toluene for 6h; Reflux;100%
2-(Chloromethyl)-6-methoxyquinoline
141770-91-4

2-(Chloromethyl)-6-methoxyquinoline

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

N,N'-bis(6-methoxy-2-quinolylmethyl)-N,N'-dimethylethylenediamine
1169761-69-6

N,N'-bis(6-methoxy-2-quinolylmethyl)-N,N'-dimethylethylenediamine

Conditions
ConditionsYield
With potassium carbonate In acetonitrile Reflux;100%
2-chloropyrazin
14508-49-7

2-chloropyrazin

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

N,N'-dimethyl-N-pyrazin-2-yl-ethane-1,2-diamine

N,N'-dimethyl-N-pyrazin-2-yl-ethane-1,2-diamine

Conditions
ConditionsYield
In ethanol100%
2-methyl-1,2-epoxypropane
558-30-5

2-methyl-1,2-epoxypropane

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

C12H28N2O2
1403990-41-9

C12H28N2O2

Conditions
ConditionsYield
at 20 - 50℃;100%
2-fluoro-3-iodopyridine
113975-22-7

2-fluoro-3-iodopyridine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

N1,N2-bis(3-iodopyridin-2-yl)-N1,N2-dimethylethane-1,2-diamine

N1,N2-bis(3-iodopyridin-2-yl)-N1,N2-dimethylethane-1,2-diamine

Conditions
ConditionsYield
With iron(III) chloride; potassium phosphate; 1,1-dimethylethyl-1-(1H-indol-3-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate In toluene at 135℃; for 48h; Inert atmosphere; Sealed tube;100%
cbz-NHS

cbz-NHS

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

benzyl methyl[2-(methylamino)ethyl]carbamate

benzyl methyl[2-(methylamino)ethyl]carbamate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 2h;100%
4-Carboxybenzaldehyde
619-66-9

4-Carboxybenzaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

4-(1,3-dimethylimidazolidin-2-yl)benzoic acid

4-(1,3-dimethylimidazolidin-2-yl)benzoic acid

Conditions
ConditionsYield
With copper(II) bis(trifluoromethanesulfonate) In water at 20℃; for 0.0333333h;100%
4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,3-dimethyl-2-(4-chlorophenyl)imidazolidine
23281-56-3

1,3-dimethyl-2-(4-chlorophenyl)imidazolidine

Conditions
ConditionsYield
With ammonium chloride for 2h; Dean-Stark; Reflux; Green chemistry;99%
With toluene-4-sulfonic acid In toluene Heating;87%
In benzene for 20h; Heating;77%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-(4-methoxyphenyl)-1,3-dimethylimidazolidine
23229-39-2

2-(4-methoxyphenyl)-1,3-dimethylimidazolidine

Conditions
ConditionsYield
With ammonium chloride for 1h; Dean-Stark; Reflux; Green chemistry;99%
In chloroform at 120℃; for 0.166667h; Molecular sieve; Microwave irradiation; Sealed tube;97%
In toluene for 5h; Heating;91%
In benzene for 20h; Heating;82%
In benzene
N-Methyl-N-(4-toluenesulphonyl)iodoethylamine
3409-85-6

N-Methyl-N-(4-toluenesulphonyl)iodoethylamine

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine
141766-05-4

1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 10h; Heating;99%
ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-(2-methoxyphenyl)-1,3-dimethylimidazolidine
124639-28-7

2-(2-methoxyphenyl)-1,3-dimethylimidazolidine

Conditions
ConditionsYield
In ethanol at 25℃; for 24h; Inert atmosphere;99%
In ethanol at 20℃;88%
In ethanol at 20℃; for 20h; Cyclization;77%
3-hydroxy-2,5-diphenyl-2-cyclopentene-1,4-dione
67106-14-3

3-hydroxy-2,5-diphenyl-2-cyclopentene-1,4-dione

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one
88288-78-2

1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one

Conditions
ConditionsYield
In methanol Inert atmosphere; Schlenk technique; Reflux;99%
In methanol Schlenk technique; Inert atmosphere; Reflux;99%
In methanol for 2h; Autoclave; Inert atmosphere; Schlenk technique; Reflux;95%
In methanol for 2h; Heating;94%
cobalt(II) chloride hexahydrate

cobalt(II) chloride hexahydrate

thiourea
17356-08-0

thiourea

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

(CoCl(C4H12N2)2(SC(NH2)2))(1+)*Cl(1-)*0.5C2H5OH = CoCl2(C4H12N2)2(SC(NH2)2)*0.5C2H5OH

(CoCl(C4H12N2)2(SC(NH2)2))(1+)*Cl(1-)*0.5C2H5OH = CoCl2(C4H12N2)2(SC(NH2)2)*0.5C2H5OH

Conditions
ConditionsYield
With C2H5OH In ethanol byproducts: H2O; Co-compound and Tu were dissolved in EtOH; Me2En was added; filtered; washed (Et2O/EtOH (3:1), Et2O); elem.anal.;99%
4-hydroxy-5-methyl-4-cyclopentene-1,3-dione
1696-34-0

4-hydroxy-5-methyl-4-cyclopentene-1,3-dione

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

1,4,5-trimethyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one
1032326-95-6

1,4,5-trimethyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one

Conditions
ConditionsYield
In methanol for 2h; Reflux;99%
1-methyl-4-nitro-1H-imidazol-2-carbaldehyde
73455-94-4

1-methyl-4-nitro-1H-imidazol-2-carbaldehyde

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

2-(1,3-dimethylimidazolidin-2-yl)-1-methyl-4-nitroimidazole
1333113-50-0

2-(1,3-dimethylimidazolidin-2-yl)-1-methyl-4-nitroimidazole

Conditions
ConditionsYield
In benzene for 2h; Reflux;99%
C8H8ClN3O2S2
1013405-86-1

C8H8ClN3O2S2

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

N,N-dimethyl-7-{methyl[2-(methylamino)ethyl]amino}-2,1,3-benzothiadiazole-4-sulfonamide
1013405-87-2

N,N-dimethyl-7-{methyl[2-(methylamino)ethyl]amino}-2,1,3-benzothiadiazole-4-sulfonamide

Conditions
ConditionsYield
In acetonitrile at 80℃; for 1h;99%
7-chloro-N,N-dimethyl-2,1,3-benzoselenadiazole-4-sulfonamide
1402567-63-8

7-chloro-N,N-dimethyl-2,1,3-benzoselenadiazole-4-sulfonamide

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

N,N-dimethyl-7-{methyl[2-(methylamino)ethyl]amino}-2,1,3-benzoselenadiazole-4-sulfonamide
1402567-65-0

N,N-dimethyl-7-{methyl[2-(methylamino)ethyl]amino}-2,1,3-benzoselenadiazole-4-sulfonamide

Conditions
ConditionsYield
In acetonitrile at 80℃; for 1h;99%
N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide
1393810-65-5

N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

(1S,2aR,8bR)-2-allyl-4-((2-nitrophenyl)sulfonyl)-1-((trityloxy)methyl)-1,2,2a,3,4,8b-hexahydroazeto[2,3-c]quinolone
1393810-67-7

(1S,2aR,8bR)-2-allyl-4-((2-nitrophenyl)sulfonyl)-1-((trityloxy)methyl)-1,2,2a,3,4,8b-hexahydroazeto[2,3-c]quinolone

Conditions
ConditionsYield
With copper(l) iodide; caesium carbonate In toluene at 100℃; for 2h; Inert atmosphere;99%

N,N'-Dimethylethylenediamine Chemical Properties

Molecular Structure of N,N'-Dimethylethylenediamine (CAS NO.110-70-3):

IUPAC Name: N,N'-dimethylethane-1,2-diamine 
Empirical Formula: C4H12N2
Molecular Weight: 88.1515
EINECS: 203-793-3
BRN: 878142
H bond acceptors: 2
H bond donors: 2
Freely Rotating Bonds: 3
Polar Surface Area: 6.48 Å2
Index of Refraction: 1.409
Molar Refractivity: 27.77 cm3
Molar Volume: 112.1 cm3
Surface Tension: 23.5 dyne/cm
Density: 0.785 g/cm3
Flash Point: 83 °F
Enthalpy of Vaporization: 35.81 kJ/mol
Boiling Point: 120 °C at 760 mmHg
Vapour Pressure: 15.5 mmHg at 25°C
Product Categories: Polyamines; Aliphatics; Amines
InChI
InChI=1/C4H12N2/c1-5-3-4-6-2/h5-6H,3-4H2,1-2H3
Smiles
C(CNC)NC

N,N'-Dimethylethylenediamine Uses

  N,N'-Dimethylethylenediamine (CAS NO.110-70-3) is used as organic synthesis or as a pharmaceutical intermediate.

N,N'-Dimethylethylenediamine Toxicity Data With Reference

1.    

ipr-mus LD50:200 mg/kg

    EJMCA5    European Journal of Medicinal Chemistry. Chimie Therapeutique. 17 (1982),235.

N,N'-Dimethylethylenediamine Consensus Reports

Reported in EPA TSCA Inventory.

N,N'-Dimethylethylenediamine Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic vapors of NOx.
Safety information of  N,N'-Dimethylethylenediamine (CAS NO.110-70-3):
Hazard Codes: C
Risk Statements: 10-34-20/21/22
R10:Flammable;
R34:Causes burns ;
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed ;
Safety Statements: 26-36/37/39-45-16
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice ;
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection ;
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) ;
S16:Keep away from sources of ignition - No smoking ;
RIDADR: UN 2734 8/PG 2
WGK Germany: 3
RTECS: KV4250000
HazardClass: 3
PackingGroup: III

N,N'-Dimethylethylenediamine Specification

  N,N'-Dimethylethylenediamine , with CAS number of 110-70-3, can be called sym-Dimethylethylenediamine ; Symmetrical dimethylethylenediamine ; N-Methyl-N-[2-(methylamino)ethyl]amine ; N,N'-Dimethylethylenediamine ; (Methyl)[2-(methylamino)ethyl]amine . N,N'-Dimethylethylenediamine (CAS NO.110-70-3) is incompatible with strong oxidizing agents, acids, acid chlorides, anhydrides, carbon dioxide. Hazardous decomposition products are nitrogen oxides, carbon monoxide, carbon dioxide. 

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