Product Name

  • Name

    N,N-Diethylhydroxylamine

  • EINECS 223-055-4
  • CAS No. 3710-84-7
  • Article Data31
  • CAS DataBase
  • Density 0.897 g/cm3
  • Solubility soluble in water
  • Melting Point -26--25 °C
  • Formula C4H11NO
  • Boiling Point 133 °C at 760 mmHg
  • Molecular Weight 89.1374
  • Flash Point 45 °C
  • Transport Information UN 1993 3/PG 3
  • Appearance Colorless transparent liquid
  • Safety 36/37-45-36/37/39-26-16
  • Risk Codes 10-21-38-40-36/37/38-20/21
  • Molecular Structure Molecular Structure of 3710-84-7 (N,N-Diethylhydroxylamine)
  • Hazard Symbols HarmfulXn
  • Synonyms DEHA;Diethylhydroxylamine;N-Hydroxydiethylamine;N-ethyl-N-hydroxyethanamine;DEHA Acid;N,N-Diethylhydroxylamine;
  • PSA 23.47000
  • LogP 0.71740

Synthetic route

diethylamine
109-89-7

diethylamine

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With 2-hydroxy-N,N,N-trimethyl ethanaminium peroxydisulfate at 20℃; for 1h; Inert atmosphere; Green chemistry; chemoselective reaction;94%
31%
With dihydrogen peroxide
With dihydrogen peroxide
With dihydrogen peroxide
acetaldehyde
75-07-0

acetaldehyde

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
palladium-carbon In methanol54%
C16H20NO2P
102269-06-7

C16H20NO2P

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With sulfuric acid In methanol for 2h; Heating;41%
ethylmagnesium iodide
10467-10-4

ethylmagnesium iodide

Nitroethane
79-24-3

Nitroethane

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether und Zers. des Reaktionsproduktes mit Wasser;
ethylmagnesium iodide
10467-10-4

ethylmagnesium iodide

Nitroethane
79-24-3

Nitroethane

A

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

B

N-ethyl-N-sec-butyl-hydroxylamine
65616-18-4

N-ethyl-N-sec-butyl-hydroxylamine

Conditions
ConditionsYield
With diethyl ether und Zers. des Reaktionsproduktes mit Wasser;
ethylmagnesium iodide
10467-10-4

ethylmagnesium iodide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether; Nitrogen dioxide und Zerlegen des oeligen Prod. mit Wasser;
Nitroethane
79-24-3

Nitroethane

ethyl magnesium (1+); iodide

ethyl magnesium (1+); iodide

A

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

B

N-ethyl-N-sec-butyl-hydroxylamine
65616-18-4

N-ethyl-N-sec-butyl-hydroxylamine

diethyl ether
60-29-7

diethyl ether

ethyl nitrate
625-58-1

ethyl nitrate

ethylmagnesium bromide

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

diethyl ether
60-29-7

diethyl ether

1,2-ethyl dinitrate
628-96-6

1,2-ethyl dinitrate

ethylmagnesium bromide

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

diethyl ether
60-29-7

diethyl ether

Pentaerythritol tetranitrate
78-11-5

Pentaerythritol tetranitrate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
und Zersetzung des Reaktionsprodukts mit Wasser;
diethyl ether
60-29-7

diethyl ether

Pentaerythritol tetranitrate
78-11-5

Pentaerythritol tetranitrate

ethylmagnesium bromide

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

diethyl ether
60-29-7

diethyl ether

glycerin trinitrate
55-63-0

glycerin trinitrate

ethylmagnesium bromide

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

ethyl nitrate
625-58-1

ethyl nitrate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether
ethyl nitrate
625-58-1

ethyl nitrate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

A

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

B

diethylamine
109-89-7

diethylamine

Conditions
ConditionsYield
With diethyl ether Zersetzen des Reaktionsprodukts mit Wasser;
1,2-ethyl dinitrate
628-96-6

1,2-ethyl dinitrate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether
Pentaerythritol tetranitrate
78-11-5

Pentaerythritol tetranitrate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether
triethylamine N-oxide
2687-45-8

triethylamine N-oxide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

glycerin trinitrate
55-63-0

glycerin trinitrate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether
diethyl-benzyl-amine oxide
854182-24-4

diethyl-benzyl-amine oxide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
at 100 - 180℃; under 1 Torr;
diethyl-benzyl-amine oxide
854182-24-4

diethyl-benzyl-amine oxide

A

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

B

N-ethyl-N,O-dibenzyl-hydroxylamine

N-ethyl-N,O-dibenzyl-hydroxylamine

C

N-benzyl-N-ethylhydroxylamine
65616-26-4

N-benzyl-N-ethylhydroxylamine

D

N,N-diethyl-O-benzyl-hydroxylamine
27694-73-1

N,N-diethyl-O-benzyl-hydroxylamine

Conditions
ConditionsYield
at 180℃; under 1 Torr; in einer Stickstoff-Atmosphaere; Prod.5: Aethylen;
diethylzinc
557-20-0

diethylzinc

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether; nitrosylchloride nach einigen Stunden zersetzt man mit Wasser;
ethyl iodide
75-03-6

ethyl iodide

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With hydroxylamine
chloroform
67-66-3

chloroform

acetyl cyclohexanesulfonyl peroxide
3179-56-4

acetyl cyclohexanesulfonyl peroxide

diethylamine
109-89-7

diethylamine

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

diethylzinc
557-20-0

diethylzinc

N-nitrosodiphenylamine
382165-80-2

N-nitrosodiphenylamine

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

ethylzinc iodide
999-75-7

ethylzinc iodide

isopentyl nitrite
110-46-3

isopentyl nitrite

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether und Zers. des Reaktionsproduktes mit Wasser;
ethylmagnesium iodide
10467-10-4

ethylmagnesium iodide

isopentyl nitrite
110-46-3

isopentyl nitrite

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether und Zers. des Reaktionsproduktes mit Wasser;
diethylzinc
557-20-0

diethylzinc

isopentyl nitrite
110-46-3

isopentyl nitrite

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Conditions
ConditionsYield
With diethyl ether das Produkt wird nach mehreren Monaten mit Wasser zersetzt;
ethyl magnesium (1+); iodide

ethyl magnesium (1+); iodide

isopentyl nitrite
110-46-3

isopentyl nitrite

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

ethyl zinc iodide

ethyl zinc iodide

isopentyl nitrite
110-46-3

isopentyl nitrite

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

diethylamine
109-89-7

diethylamine

A

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

B

3-aza-2-pentene
1190-79-0

3-aza-2-pentene

C

N,N'-diethyl-2,3-butanediamine
3653-18-7

N,N'-diethyl-2,3-butanediamine

Conditions
ConditionsYield
With oxygen Quantum yield; Ambient temperature; Irradiation; Hg-sensitized photolysis presence and absence O2, or N2O at various pressure and time;
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

N-ethyl-N-ethylideneamine N-oxide
70524-55-9, 81206-52-2, 81206-53-3

N-ethyl-N-ethylideneamine N-oxide

Conditions
ConditionsYield
With ~ 5 mol% gold on silica In methanol at 20℃; for 16h; chemoselective reaction;100%
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dichloromethane at 20℃; for 2h; Mechanism; Reagent/catalyst; Solvent;96%
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dichloromethane at 20℃; for 2h;96%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

2,4,6-trichlorobenzoyl chloride
4136-95-2

2,4,6-trichlorobenzoyl chloride

N,N-diethyl-O-(2,4,6-trichlorobenzoyl)hydroxylamine

N,N-diethyl-O-(2,4,6-trichlorobenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.333333h;100%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

1-(((5-chloro-3,3-difluoropent-4-yn-1-yl)oxy)methyl)-4-methoxybenzene

1-(((5-chloro-3,3-difluoropent-4-yn-1-yl)oxy)methyl)-4-methoxybenzene

(Z)-1-chloro-N,N-diethyl-3,3-difluoro-5-((4-methoxybenzyl)oxy)pent-1-en-1-amine N-oxide

(Z)-1-chloro-N,N-diethyl-3,3-difluoro-5-((4-methoxybenzyl)oxy)pent-1-en-1-amine N-oxide

Conditions
ConditionsYield
In chloroform; 2,2,2-trifluoroethanol at 22.5℃; for 3h; Kinetics; Inert atmosphere;100%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

1-((2-((1,1-difluoroprop-2-yn-1-yl)oxy)ethoxy)methyl)-4-methoxybenzene

1-((2-((1,1-difluoroprop-2-yn-1-yl)oxy)ethoxy)methyl)-4-methoxybenzene

(E)-N,N-diethyl-3,3-difluoro-3-(2-((4-methoxybenzyl)oxy)ethoxy)prop-1-en-1-amine N-oxide

(E)-N,N-diethyl-3,3-difluoro-3-(2-((4-methoxybenzyl)oxy)ethoxy)prop-1-en-1-amine N-oxide

Conditions
ConditionsYield
In chloroform; 2,2,2-trifluoroethanol at 60℃; for 0.666667h; Kinetics; Inert atmosphere;100%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

N,N-diethyl-O-(4-methoxybenzoyl)hydroxylamine

N,N-diethyl-O-(4-methoxybenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.75h;99%
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;94%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

mesitylene-2-carboxylic acid chloride
938-18-1

mesitylene-2-carboxylic acid chloride

N,N-diethyl-O-(2,4,6-trimethylbenzoyl)hydroxylamine
936138-68-0

N,N-diethyl-O-(2,4,6-trimethylbenzoyl)hydroxylamine

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 2.5h;99%
With dmap; triethylamine In dichloromethane at 20℃; for 0.5h;63%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

N,N-diethylhydroxylamine potassium salt
90527-23-4

N,N-diethylhydroxylamine potassium salt

Conditions
ConditionsYield
With potassium hydride In pentane at -78 - 20℃; Inert atmosphere;99%
cyclooctyne
1781-78-8

cyclooctyne

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

(E)-N,N-diethylcyclooct-1-en-1-amine oxide

(E)-N,N-diethylcyclooct-1-en-1-amine oxide

Conditions
ConditionsYield
In acetonitrile at 20℃; for 0.166667h; Kinetics; Solvent; Inert atmosphere;99%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

1-((2-((1,1-difluoro-3-iodoprop-2-yn-1-yl)oxy)ethoxy)methyl)-4-methoxybenzene

1-((2-((1,1-difluoro-3-iodoprop-2-yn-1-yl)oxy)ethoxy)methyl)-4-methoxybenzene

(Z)-N,N-diethyl-3,3-difluoro-1-iodo-3-(2-((4-methoxybenzyl)oxy)ethoxy)prop-1-en-1-amine N-oxide

(Z)-N,N-diethyl-3,3-difluoro-1-iodo-3-(2-((4-methoxybenzyl)oxy)ethoxy)prop-1-en-1-amine N-oxide

Conditions
ConditionsYield
In chloroform; 2,2,2-trifluoroethanol at 60℃; for 0.5h; Kinetics; Inert atmosphere;99%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

benzoyl chloride
98-88-4

benzoyl chloride

N,N-diethyl-O-benzoylhydroxylamine
61582-64-7

N,N-diethyl-O-benzoylhydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.5h;98%
With triethylamine In dichloromethane at 20℃; for 0.666667h;98%
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere;98%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

ortho-toluoyl chloride
933-88-0

ortho-toluoyl chloride

N,N-diethyl-O-(2-methylbenzoyl)hydroxylamine

N,N-diethyl-O-(2-methylbenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;96%
With dmap; triethylamine In dichloromethane at 20℃; for 3h;89%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

trans-[PtCl4(NH=(Me)C-ONEt2)2]
245414-26-0

trans-[PtCl4(NH=(Me)C-ONEt2)2]

Conditions
ConditionsYield
In acetonitrile 20-25°C, 1 d; solvent removal (vac.), washing (Et2O); elem. anal.;96%
2-Thiophenecarbonyl chloride
5271-67-0

2-Thiophenecarbonyl chloride

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

N,N-diethyl-O-(thiophene-2-carbonyl)hydroxylamine
1621478-71-4

N,N-diethyl-O-(thiophene-2-carbonyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;96%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

naphthalene-1-carbonic acid chloride
879-18-5

naphthalene-1-carbonic acid chloride

N,N-diethyl-O-(1-naphthoyl)hydroxylamine
1621478-72-5

N,N-diethyl-O-(1-naphthoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;96%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

4-chloro-benzoyl chloride
122-01-0

4-chloro-benzoyl chloride

N,N-diethyl-O-(4-chlorobenzoyl)hydroxylamine
1621478-66-7

N,N-diethyl-O-(4-chlorobenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;95%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

3-Methylbenzoyl chloride
1711-06-4

3-Methylbenzoyl chloride

N,N-diethyl-O-(3-methylbenzoyl)hydroxylamine
1621478-69-0

N,N-diethyl-O-(3-methylbenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;95%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Methacryloyl chloride
920-46-7

Methacryloyl chloride

N,N-diethyl-O-methacryloylhydroxylamine
44979-02-4

N,N-diethyl-O-methacryloylhydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;95%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

2,6-Dichlorobenzoyl chloride
4659-45-4

2,6-Dichlorobenzoyl chloride

O-(2,6-dichlorobenzoyl)-N,N-diethylhydroxylamine

O-(2,6-dichlorobenzoyl)-N,N-diethylhydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;95%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol
1263166-90-0

(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

(1R,8S,9S,E)-N,N-diethyl-9-(hydroxymethyl)bicyclo[6.1.0]non-4-en-4-amine oxide

(1R,8S,9S,E)-N,N-diethyl-9-(hydroxymethyl)bicyclo[6.1.0]non-4-en-4-amine oxide

Conditions
ConditionsYield
In methanol; acetonitrile at 20℃; for 0.166667h; Kinetics; Solvent; Inert atmosphere;95%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

1-((2-((3-bromo-1,1-difluoroprop-2-yn-1-yl)oxy)ethoxy)methyl)-4-methoxybenzene

1-((2-((3-bromo-1,1-difluoroprop-2-yn-1-yl)oxy)ethoxy)methyl)-4-methoxybenzene

(Z)-1-bromo-N,N-diethyl-3,3-difluoro-3-(2-((4-methoxybenzyl)oxy)ethoxy)prop-1-en-1-amine N-oxide

(Z)-1-bromo-N,N-diethyl-3,3-difluoro-3-(2-((4-methoxybenzyl)oxy)ethoxy)prop-1-en-1-amine N-oxide

Conditions
ConditionsYield
In chloroform; 2,2,2-trifluoroethanol at 60℃; for 0.25h; Kinetics; Inert atmosphere;95%
Cp*TiCl3
12129-06-5

Cp*TiCl3

N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

Cp*Ti(Cl)2(ONEt2)
1097730-83-0

Cp*Ti(Cl)2(ONEt2)

Conditions
ConditionsYield
With N-butyl lithium In hexane; toluene under N2 atm. n-BuLi in hexane was added dropwise to soln. HONEt2 in toluene at 0°C and stirred for 30 min, suspn. Ti complex in toluene was added at -78°C, stirred for 4 h at room temp.; soln. was filtered and evapd. in vacuo; elem. anal.;94.7%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

cyclooct-2-yn-1-yl (4-nitrophenyl)carbamate

cyclooct-2-yn-1-yl (4-nitrophenyl)carbamate

(E)-N,N-diethyl-3-(((4-nitrophenyl)carbamoyl)oxy)cyclooct-1-en-1-amine oxide

(E)-N,N-diethyl-3-(((4-nitrophenyl)carbamoyl)oxy)cyclooct-1-en-1-amine oxide

Conditions
ConditionsYield
In acetonitrile at 20℃; for 0.166667h; Kinetics; Solvent; Inert atmosphere;94%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

3,3-difluorocyclooct-1-yne

3,3-difluorocyclooct-1-yne

(E)-N,N-diethyl-3,3-difluorocyclooct-1-en-1-amine oxide

(E)-N,N-diethyl-3,3-difluorocyclooct-1-en-1-amine oxide

Conditions
ConditionsYield
In acetonitrile at 20℃; for 0.0833333h; Kinetics; Solvent; Inert atmosphere;94%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

4-methyl-benzoyl chloride
874-60-2

4-methyl-benzoyl chloride

N,N-diethyl-O-(4-methylbenzoyl)hydroxylamine
1621478-65-6

N,N-diethyl-O-(4-methylbenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;92%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

4-fluorobenzoyl chloride
403-43-0

4-fluorobenzoyl chloride

N,N-diethyl-O-(4-fluorobenzoyl)hydroxylamine
1621478-67-8

N,N-diethyl-O-(4-fluorobenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;92%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

4-trifluoromethyl-phenyl acetyl chloride
329-15-7

4-trifluoromethyl-phenyl acetyl chloride

N,N-diethyl-O-(4-(trifluoromethyl)benzoyl)hydroxylamine
1621478-68-9

N,N-diethyl-O-(4-(trifluoromethyl)benzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;92%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

3,5-dichlorobenzoyl chloride
2905-62-6

3,5-dichlorobenzoyl chloride

N,N-diethyl-O-(3,5-dichlorobenzoyl)hydroxylamine
1621478-70-3

N,N-diethyl-O-(3,5-dichlorobenzoyl)hydroxylamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;92%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

diethylzinc
557-20-0

diethylzinc

Zn(OZn(C2H5)N(C2H5)2)4(ON(C2H5)2)2
948296-99-9

Zn(OZn(C2H5)N(C2H5)2)4(ON(C2H5)2)2

Conditions
ConditionsYield
In tetrahydrofuran; hexane byproducts: C2H6; N2, a soln. of N compd. (THF) slowly added to a soln. of Zn compd. (hexane) at 0°C, cooling removed, stirred until gas evolution had ceased; volatiles removed (vac.), extd. (hexane/diethyl ether), filtered, concd.(vac.), stored (-26°C, several d); elem. anal.;91%
N-ethyl-N-hydroxy-ethanamine
3710-84-7

N-ethyl-N-hydroxy-ethanamine

1,4-dioxaspiro[4.7]dodec-6-yne

1,4-dioxaspiro[4.7]dodec-6-yne

(E)-N,N-diethyl-1,4-dioxaspiro[4.7]dodec-6-en-7-amine oxide

(E)-N,N-diethyl-1,4-dioxaspiro[4.7]dodec-6-en-7-amine oxide

Conditions
ConditionsYield
In acetonitrile at 20℃; for 0.166667h; Kinetics; Solvent; Inert atmosphere;91%

N,N-Diethylhydroxylamine Consensus Reports

Diethylhydroxylamine(3710-84-7) is reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

N,N-Diethylhydroxylamine Specification

The IUPAC name of Diethylhydroxylamine is N,N-diethylhydroxylamine. With the CAS registry number 3710-84-7, it is also named as N-Hydroxydiethylamine. The product's categories are Fine Chemical & Intermediate; Hydroxylamines; Hydroxylamines (N-Substituted); Nitrogen Compounds; Organic Building Blocks. It is colorless transparent liquid which is easily soluble in water, soluble in alcohol, ether, chloroform and benzene. In addition, this chemical is stable and incompatible with strong oxidizing agents, strong acids. Moreover, it should be sealed in the container and stored in the cool and dry place.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -0.09; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.49; (4)ACD/LogD (pH 7.4): -0.1; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 8.38; (8)ACD/KOC (pH 7.4): 20.95; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Index of Refraction: 1.433; (13)Molar Refractivity: 25.83 cm3; (14)Molar Volume: 99.3 cm3; (15)Polarizability: 10.24×10-24 cm3; (16)Surface Tension: 30.6 dyne/cm; (17)Enthalpy of Vaporization: 40.88 kJ/mol; (18)Vapour Pressure: 5.15 mmHg at 25°C; (19)Rotatable Bond Count: 2; (20)Exact Mass: 89.084064; (21)MonoIsotopic Mass: 89.084064; (22)Topological Polar Surface Area: 23.5; (23)Heavy Atom Count: 6; (24)Complexity: 26.7.

Preparation of Diethylhydroxylamine: It can be obtained by the oxidation reaction of hydrogen peroxide aqueous solution and secondary amine at the presence of CdCl2 or ZnCl2.
 

Uses of Diethylhydroxylamine: It is a free radical scavenger which can be used in polymerization inhibitor, color stabilizer (photographics), oxygen scavenger (water treatment), corrosion inhibitor and discoloration inhibitor (phenolics). Additonally, it can react with N-phenyl-maleimide to get N-phenyl-3-[(N,N-dibenzylamino)oxy]pyrrolidine-2,5-dione. This reaction needs reagent tetrahydrofuran by heating. The reaction time is 9.5 hours. The yield is 46%.

When you are using this chemical, please be cautious about it as the following:
It is flammable, so people should keep it away from sources of ignition. This chemical is not only harmful by inhalation and in contact with skin, but also irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 

People can use the following data to convert to the molecule structure.
1. SMILES:ON(CC)CC
2. InChI:InChI=1/C4H11NO/c1-3-5(6)4-2/h6H,3-4H2,1-2H3 
3. InChIKey:FVCOIAYSJZGECG-UHFFFAOYAL

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 skin 100uL/kg (0.1mL/kg)   Kodak Company Reports. Vol. 21MAY1971,
mouse LD80 oral 2150mg/kg (2150mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 217, 1969.
mouse LDLo intraperitoneal 1750mg/kg (1750mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 217, 1969.
rabbit LDLo skin 2gm/kg (2000mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 217, 1969.
rat LDLo oral 1600mg/kg (1600mg/kg)   Kodak Company Reports. Vol. 21MAY1971,
rat LDLo skin 100mg/kg (100mg/kg)   Kodak Company Reports. Vol. 21MAY1971,

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View