Nitrous oxide supplier | CasNO.10024-97-2

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Name
NITROUS OXIDE
EINECS 233-032-0
CAS No. 10024-97-2
Article Data1290
CAS DataBase
Density 1.469 g/cm³
Solubility 670,000 mg l-1
Melting Point -91 °C(lit.)
Formula N₂O
Boiling Point -88 °C(lit.)
Molecular Weight 44.0134
Flash Point
Transport Information UN 1070 2.2
Appearance Colourless gas with sweetish odour
Safety 38
Risk Codes 8
Molecular Structure
Hazard Symbols O
Synonyms Dinitrogenmonoxide;Dinitrogen oxide;Dinitrogen oxide (N2O);Factitious air;Hyponitrousacid anhydride;Laughing gas;Nitrous oxide;R 744A;? Nitrous oxide;
PSA 54.46000
LogP 0.06366

Synthetic route

: 7664-41-7
ammonia

: 80937-33-3
oxygen

A: 7727-37-9
nitrogen

B: 10102-43-9
nitrogen(II) oxide

C: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With oxygen In neat (no solvent) Fe-ZSM-5 catalyst prepared by ion exchange and heat-treated at 400, 425or 450 °C, 100 % NH3 conversion, 100 % N2 selectivity, 1000 ppm NH3 in 2 % O2-contg. He;	A 100% B 0% C 0%
With catalyst:Fe-mordenite In neat (no solvent) Fe-mordenite catalyst prepared by ion exchange and heat-treated at 425 °C, 92 % NH3 conversion, 99 % N2 selectivity, 1000 ppm NH3 in 2 %O2-contg. He;	A 92% B n/a C 0%
With catalyst:Fe-ZSM-5 In neat (no solvent) Fe-ZSM-5 catalyst prepared by ion exchange and heat-treated at 375 °C, 90 % NH3 conversion, 99 % N2 selectivity, 1000 ppm NH3 in 2 % O2-contg. He;	A 90% B n/a C 0%

...Expand

: [Fe2(2,6-bis[[bis(2-pyridylmethyl)amino]methyl]-4-methylphenolato)(propionato)(NO)2](triflate)2

: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With cobaltocene In dichloromethane at 20℃; for 0.0166667h; Kinetics; Time; Temperature; Concentration;	100%

: 7664-41-7
ammonia

A: 7727-37-9
nitrogen

B: 10102-43-9
nitrogen(II) oxide

C: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With oxygen In neat (no solvent) Fe-mordenite catalyst prepared by ion exchange and heat-treated at 450 °C, 99 % NH3 conversion, 100 % N2 selectivity, 1000 ppm NH3 in 2 % O2-contg. He;	A 99% B 0% C 0%
With oxygen; platinum high excess O2,500 °C;	A <1 B n/a C n/a
With oxygen; platinum at 300 °C;	A n/a B <9 C n/a

...Expand

: 114581-86-1
[CuI(tris(2-pyridylmethyl)amine)(CH3CN)]2+

: 10102-43-9
nitrogen(II) oxide

A: 133578-96-8
[Cu(tris(2-pyridylmethyl)amine)(H2O)](2+)

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In water room temp., pH = 7.0; reaction followed by gas chromy.;	A 99% B n/a

...Expand

: ammonium nitrate

A: 7727-37-9
nitrogen

B: 10102-43-9
nitrogen(II) oxide

C: 10102-44-0
Nitrogen dioxide

D: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
at 220-260°C, nearly 98% N2O, 2% N2; troces of NO and NO2 (0.001%);	A 2% B n/a C n/a D 98%

...Expand

: 1112-04-5
trifluoromethyldifluorophosphine

: 10102-43-9
nitrogen(II) oxide

A: 19162-94-8
Trifluormethylphosphonsaeuredifluorid

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
20°C (7 d); oxydation;	A 98% B n/a

...Expand

: [(copper(II)(tris(2-pyridylmethyl)amine))2(μ-hyponitrite)](2+)

: 10102-43-9
nitrogen(II) oxide

A: 188637-84-5
[copper(I)(tris(2-pyridylmethyl)amine)](1+)

B: [copper(II)(tris(2-pyridylmethyl)amine)(nitrito)](1+)

C: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In tetrahydrofuran; methanol for 8h; Solvent; Inert atmosphere; Schlenk technique;	A 96% B 85% C 98%

...Expand

: {Cu2(NO)N6OC36H39}(2+)

: tetrabutylammonium nitrite

A: {Cu2(O)N6OC36H39}(1+)*PF6(1-)={Cu2(O)N6OC36H39}PF6

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With P(C6H5)3 In not given byproducts: OP(C6H5)3; react. of 1 equiv. N(C4H9)4(NO2) with (Cu2(NO)N6OC36H39)(2+) in presence of P(C6H5)3 (1 equiv.);; elem. anal.;	A 60% B 97%
In not given byproducts: O2; react. of 1 equiv. N(C4H9)4(NO2) with (Cu2(NO)N6OC36H39)(2+);; elem. anal.;	A 60% B 79%

...Expand

: 90065-16-0
Cu2(I)(C6H3(O)(CH2N(C2H4-2-pyridyl)2)2)(1+)

: 10102-43-9
nitrogen(II) oxide

A: {Cu2(O)N6OC36H39}(1+)*PF6(1-)={Cu2(O)N6OC36H39}PF6

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In dichloromethane exposure of (Cu2N6OC36H39)(1+) to NO(g) in CH2Cl2 at -80 °C, warming;;	A 55% B 96%

...Expand

: trans-hydroxotetraamminenitrosoruthenium(II)

: 7697-37-2
nitric acid

: trans-tetraamminenitratonitrosoruthenium(III) nitrate

B: 7732-18-5
water

C: 10102-44-0
Nitrogen dioxide

D: 2696-92-6
nitrosylchloride

E: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In nitric acid byproducts: Cl2; to Ru complex was added concd. HNO3; mixt. heated under reflux for 5 min; cooled to room temp.; ppt. filtered off; washed (water, alc., ether); dried (vac.); recrystd. (aq. HNO3); elem. anal.;	A 95% B n/a C n/a D n/a E n/a

...Expand

: 1194657-31-2
4-nitrosotetrahydro-2H-pyran-4-yl 2,2,2-trichloroacetate

A: 29943-42-8
Tetrahydro-4H-pyran-4-one

B: 10024-97-2
dinitrogen monoxide

C: 76-03-9
trichloroacetic acid

Conditions

Conditions	Yield
With water In methanol; aq. phosphate buffer at 20℃; for 24h; pH=7.4; Kinetics; Reagent/catalyst; Sealed tube;	A n/a B 95% C n/a

...Expand

: 7664-41-7
ammonia

A: 7727-37-9
nitrogen

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With oxygen In gaseous matrix byproducts: NO; 0.2 g of catalyst, 1000 ppm NH3, 2% O2, He as balance, GHSV=2.0E+5 h**-1, at 450°C; mass spect.;	A 94% B 0%
With oxygen In gaseous matrix byproducts: NO; 0.2 g of catalyst, 1000 ppm NH3, 2% O2, He as balance, GHSV=2.0E+5 h**-1, at 400°C; mass spect.;	A 93% B 0%
With oxygen In gaseous matrix byproducts: NO; 0.2 g of catalyst, 1000 ppm NH3, 2% O2, He as balance, GHSV=2.0E+5 h**-1, at 400°C; mass spect.;	A 92% B 0%

: 1493-13-6
trifluorormethanesulfonic acid

: [Fe2(NO)4(μ-1,3-bis(dimethylamino)-2-propanolate)]2(κ4-N2O2)

A: [Fe2(NO)4(μ-1,3-bis(dimethylamino)-2-propanolate)(μ-OSO2CF3)]

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In tetrahydrofuran at 0℃; for 1h; Schlenk technique; Inert atmosphere;	A n/a B 93%

...Expand

: 4-nitrosotetrahydro-2H-pyran-4-yl 2,2-dichloropropanoate

A: 29943-42-8
Tetrahydro-4H-pyran-4-one

B: 75-99-0
2,2-Dichloropropionic acid

C: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With water In methanol; aq. phosphate buffer at 20℃; for 24h; pH=7.4; Kinetics; Reagent/catalyst; Sealed tube;	A n/a B n/a C 92%

...Expand

: C46H57Fe2N13O4S(2+)*2BF4(1-)

A: C43H49Fe2N10O2(2+)

B: 2C39H41N10O(1-)*2Fe(2+)*2Fe(3+)*4HO(1-)

C: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With cobaltocene In dichloromethane for 0.0833333h; Sealed tube; Inert atmosphere;	A n/a B n/a C 91%

...Expand

: 10102-43-9
nitrogen(II) oxide

A: 7727-37-9
nitrogen

B: 80937-33-3
oxygen

C: 10102-44-0
Nitrogen dioxide

D: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
Irradiation (UV/VIS); irradn. with Al-glitter (wave length:1860,1930 and 1990 A);	A 90% B 90% C 10% D 10%
Irradiation (UV/VIS); irradn. with Al-glitter (wave length:1860,1930 and 1990 A);	A 90% B 90% C 10% D 10%
La0.7Ba0.3Mn0.8In0.1Cu0.1O3 In neat (no solvent) decomposition over catalyst at 1073 K;	A 69.4% B 42.3% C 27.1% D 0%

...Expand

: 7664-41-7
ammonia

: 80937-33-3
oxygen

: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
manganese(II) oxide In neat (no solvent) catalytic oxidn. of NH3 (300 °C, O2-excess);;	90%
byproducts: N2, NO; excess of O2; at 300 °C; catalyst MnO2/Fe2O3/(eventually) Bi2O3; yield depending on mole ratio O2:NH3 and flow rate;;	90%
cobalt(II) oxide In neat (no solvent) oxidation at 300°C;;

: 7664-41-7
ammonia

: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With oxygen 300 °C,with air;	90%
Electrolysis; NH3 soln. contg. CO2;anod contains Pt,Pd or Fe;	14.6%
Electrolysis;

: Nitrite

: tin(ll) chloride

A: 7803-49-8
hydroxylamine

B: 10024-97-2
dinitrogen monoxide

C: 19467-31-3, 173728-04-6
trans-hyponitrous acid

Conditions

Conditions	Yield
In water	A n/a B 90% C n/a

...Expand

: 7782-77-6
cis-nitrous acid

: tin(ll) chloride

A: 7803-49-8
hydroxylamine

B: 10024-97-2
dinitrogen monoxide

C: 19467-31-3, 173728-04-6
trans-hyponitrous acid

Conditions

Conditions	Yield
In water	A n/a B 90% C n/a

...Expand

: copper(II)-hyponitrite

A: 7727-37-9
nitrogen

B: 10102-43-9
nitrogen(II) oxide

C: copper(II) oxide

D: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In neat (no solvent) decompn. at 225-230°C;;	A 2-6 B 3-5 C n/a D 90%
In neat (no solvent) decompn. at 225-230°C;;	A 2-6 B 3-5 C n/a D 90%

...Expand

: 7803-49-8
hydroxylamine

A: 10024-97-2
dinitrogen monoxide

B: nitrosyl hydride

Conditions

Conditions	Yield
With hypochloric acid In aq. phosphate buffer at 37℃; pH=7.4;	A n/a B 90%

: 7758-09-0
potassium nitrite

: hydrazin sulfate

A: 7727-37-9
nitrogen

B: 10024-97-2
dinitrogen monoxide

C: 19467-31-3, 173728-04-6
trans-hyponitrous acid

Conditions

Conditions	Yield
In not given at room temp. or upon boiling from equimolar amounts in 3% solns.; no formation of H2N2O2 even in concd. solns. at low temps.; mole ratio of N2O:N2 depends on the mole ratio nitrite:hydrazonium salt;;	A 11% B 89% C 0%

...Expand

: C52H70Fe2N14O5(3+)*3BF4(1-)

: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With cobaltocene In dichloromethane for 0.0833333h; Inert atmosphere;	89%
With silver; N,N,N,N-tetraethylammonium tetrafluoroborate In dichloromethane Inert atmosphere; Electrochemical reaction;	89%

: 7803-49-8
hydroxylamine

A: 7727-37-9
nitrogen

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
With Hg2(NO3)2 In not given byproducts: Hg; addn. of 0.04 M NH2OH to 0.005 M Hg2(NO3)2 soln. buffered with acetate at 20°C, autocatalysis of reaction by Hg;;	A 13% B 87%
With Hg2(NO3)2; silver In not given byproducts: Hg; addn. of 0.04 M NH2OH to 0.005 M Hg2(NO3)2 soln. buffered with acetate at 20°C, autocatalysis of reaction by Hg, further catalysis by addn. of collodial Ag soln.;;	A 63% B 34%
With oxygen In not given byproducts: water; Electrolysis; N2O formed on cathode, N2 formed on anode;

: [(copper(II)(tris(2-pyridylmethyl)amine))2(μ-hyponitrite)](2+)

: 10102-43-9
nitrogen(II) oxide

A: [copper(II)(tris(2-pyridylmethyl)amine)(nitrito)](1+)

B: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
In methanol Inert atmosphere; Schlenk technique;	A 85% B n/a

...Expand

: 463-51-4
Ketene

: 10102-43-9
nitrogen(II) oxide

A: 51060-05-0
fulminic acid

B: 74-90-8
hydrogen cyanide

C: 201230-82-2
carbon monoxide

D: 7732-18-5
water

E: 10024-97-2
dinitrogen monoxide

Conditions

Conditions	Yield
byproducts: H2CO; Irradiation (UV/VIS); photolysis of CH2CO/NO/Ar mixt. with 200 W high pressure Hg lamp (photolysis of CH2CO generates CH2 radicals) in Duran glass tube (20 cm long, 4cm i.d.) at room temp. and ambient pressure;	A 84% B 15% C n/a D n/a E n/a

...Expand

: bis(η5.-pentamethylcyclopentadienyl)(η2-phenyltrimethylsilylacetylene)zirconium

: 10024-97-2
dinitrogen monoxide

: 205107-24-0
(η(5)-C5Me5)2Zr(OCPh=CSiMe3)

Conditions

Conditions	Yield
In neat (no solvent) byproducts: N2; absence of air and moisture; 500 Torr N2O, room temp., 24 h; removal of gases; elem. anal.;	100%
In toluene byproducts: N2; absence of air and moisture; N2O-atmosphere, warming from -78°C to room temp., stirring for 30 min; rsolvent removal, recrystn. (hexane/O(SiMe3)2);	65%
In benzene absence of air and moisture;

: (η(5)-C5Me5)2Zr(Me3SiC.tplbond.C(c-C5H9))

: 10024-97-2
dinitrogen monoxide

: 205107-25-1
(η(5)-C5Me5)2Zr(OC(c-C5H9)=CSiMe3)

Conditions

Conditions	Yield
In neat (no solvent) byproducts: N2; absence of air and moisture; 500 Torr N2O, room temp., 24 h; removal of gases; elem. anal.;	100%
In benzene absence of air and moisture;

: (((p-tolyl)B(pyrazolyl)2)2Py)ScH

: 10024-97-2
dinitrogen monoxide

: (((p-tolyl)B(pyrazolyl)2)2Py)Sc-O-Sc(((p-tolyl)B(pyrazolyl)2)2Py)

Conditions

Conditions	Yield
In benzene-d6 at 80℃; under 760.051 Torr; for 18h; Inert atmosphere; Schlenk technique;	100%

: 34557-54-5
methane

: 10024-97-2
dinitrogen monoxide

A: 67-56-1
methanol

B: 50-00-0
formaldehyd

C: 124-38-9
carbon dioxide

D: 201230-82-2
carbon monoxide

E: 7727-37-9
nitrogen

Conditions

Conditions	Yield
In neat (no solvent) Kinetics; Oxidation of CH4 by N2O in presence of catalyst (773 K): deposited Cu(2+) on carbon;;	A 0.2% B 0.3% C 99.5% D 0% E n/a
In neat (no solvent) Kinetics; byproducts: C2H5OH (small quantity); oxidation of CH4 by N2O in presence of catalyst (773 K): deposited Ti(4+) on carbon;;	A 13.8% B 0% C 86.2% D 0% E n/a
In neat (no solvent) Kinetics; Oxidation of CH4 by N2O in presence of catalyst (773 K): deposited Co(2+) on carbon;;	A 0% B 0% C 75% D 25% E n/a

...Expand

: potassium amide

: 10024-97-2
dinitrogen monoxide

: 20762-60-1
potassium azide

Conditions

Conditions	Yield
byproducts: KOH, NH3; 270-280 °C in rotating furnace; the white layer of KOH and KN3 dissolved in water, the soln. evaporated, KN3 crystd.;	99%
byproducts: KOH, NH3; 270-280 °C in rotating furnace; the white layer of KOH and KN3 dissolved in water, the soln. evaporated, KN3 crystd.;	99%
In ammonia byproducts: KOH, NH3; -70°C;
In ammonia byproducts: KOH, NH3; NH3 (liquid); -70°C;

: 7783-54-2
nitrogen trifluoride

: 7783-70-2
antimony pentafluoride

: 10024-97-2
dinitrogen monoxide

: 12528-55-1
NF2O(1+)*Sb2F11(1-) =(NF2O)(Sb2F11)

Conditions

Conditions	Yield
byproducts: N2; 150°C;	99%
100°C;	0%

...Expand

: 1039748-93-0
N[2-P(CHMe3)2-4-methylphenyl]2V(CH2tBu)2

: 10024-97-2
dinitrogen monoxide

: V(N[4-Me-2-(PiPr2)C6H3]2)(CHtBu)O*0.5C5H10

Conditions

Conditions	Yield
In benzene V-complex reacted with N2O in benzene at 90°C;	99%

: (η5-C5Me5)*W{N(iPr)C(Me)N(iPr)}(NSiMe3)

: 10024-97-2
dinitrogen monoxide

: (η5-C5Me5)W[N(iPr)C(Me)N(iPr)](nitrido)(OSiMe3)

Conditions

Conditions	Yield
at 25℃; for 216h;	99%

: 328396-60-7
bis[2,6-bis(1-naphthyl)phenyl]germylene

: 10024-97-2
dinitrogen monoxide

: 327179-04-4
bis[2,6-bis(1-naphthyl)phenyl]germanone

Conditions

Conditions	Yield
In toluene left standing under N2 for 2 d; solvent evpd. in vacuo;	98%

: potassium diphenylphosphanylborohydride

: 10024-97-2
dinitrogen monoxide

: KOPPh2BH3

Conditions

Conditions	Yield
In tetrahydrofuran soln. of B compd. stirred at room temp. under N2O atm. until gas evolution stopped (ca. 5 min); evapd., elem. anal.;	98%

: K[P((t)Bu)2BH3]

: 10024-97-2
dinitrogen monoxide

: K(1+)*OP(C(CH3)3)2BH3(1-)=K[(C(CH3)3)2OPBH3]

Conditions

Conditions	Yield
In tetrahydrofuran soln. of B compd. stirred at room temp. under N2O atm. until gas evolution stopped (ca. 5 min); evapd., elem. anal.;	98%

: [{(i-Bu)2(aminotroponiminate)Ge(i-Pr)(ZnCl2)}2]

: 10024-97-2
dinitrogen monoxide

: [{(i-Bu)2ATIGe(O)(i-Pr)(ZnCl2)}2]

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere; Schlenk technique;	98%

: [(C(C6H4P(CH(CH3)2)2)2)IrCl]

: 10024-97-2
dinitrogen monoxide

: C25H36ClIrOP2

Conditions

Conditions	Yield
In benzene-d6 at 20℃; under 760.051 Torr; for 24h;	98%

: 1033858-47-7
ethylenebis(1,3-di-tert-butylcyclopentadienyl)titanium

: 10024-97-2
dinitrogen monoxide

A: 827030-28-4
μ-oxotetrakis(1,3-di-tert-butylcyclopentadienyl)dititanium

B: 1033858-56-8
di-μ-oxotetrakis(1,3-di-tert-butylcyclopentadienyl)dititanium

Conditions

Conditions	Yield
In pentane Ti complex dissolved in pentane; exposed to N2O (1 atm); solvent removed under vac.; extd. into hot toluene; cooled to room temp.and then to -20°C; crystals isolated; elem. anal.;	A 0% B 97%

...Expand

: 382150-90-5
(HC(CMeNC-2,6-i-Pr2C6H3)2)-germanium(II) hydride

: 10024-97-2
dinitrogen monoxide

: 692776-46-8
(HC(CMeNC-2,6-i-Pr2C6H3)2)-germanium(II) hydroxide

Conditions

Conditions	Yield
In toluene under N2 or Ar; dry N2O bubbled into soln. of Ge compd. in toluene at room temp. for 30 min; volatiles removed in vac.; treated with n-hexane; filtered; dried in vac.;	95%

: C20H46BN2P

: 10024-97-2
dinitrogen monoxide

: C20H46BN2OP

Conditions

Conditions	Yield
In toluene at 20℃; under 760.051 Torr; for 24h; Cooling with liquid nitrogen; Inert atmosphere;	94%

: [(2,6-(2,4,6-Me3C6H2)2C6H3)Ge-(1,3,4,5-tetramethylimidazol-2-ylidene)2][(3,5-(CF3)2C6H3)4B]

: 10024-97-2
dinitrogen monoxide

: [(2,6-(2,4,6-Me3C6H2)2C6H3)Ge(O)(1,3,4,5-tetramethylimidazol-2-ylidene)2][(3,5-(CF3)2C6H3)4B]

Conditions

Conditions	Yield
In acetonitrile Inert atmosphere;	94%

Nitrous oxide Chemical Properties

IUPAC Name: Nitrous oxide
Molecular formula: N₂O
Molar mass: 44.01
EINECS: 233-032-0
Appearance: colorless gas
Index of Refraction: 1.469
Molar Refractivity: 8.35 cm³
Molar Volume: 29.9 cm³
Surface Tension: 70.7 dyne/cm
Density: 1.46 g/cm³
Melting point: -90.86 °C (182.29 K)
Boiling point: -88.48 °C (184.67 K)
Solubility in water: 0.15 g/100 ml (15 °C)
Stability: Oxidant, strongly supports combustion. May react violently with some materials. Thermal decomposition yields toxic products. Incompatible with aluminium, boron oxides, hydrazine, strong reducing agents.
log P: 0.35
Vapor pressure: 5150 kPa (20 °C)
Classification Code of Nitrous oxide (CAS NO.10024-97-2): Analgesics; Analgesics, non-narcotic; Anesthetic [inhalation]; Anesthetics; Anesthetics, General; Anesthetics, inhalation; Central Nervous System Agents; Central Nervous System Depressants; Human Data; Mutation data; Peripheral Nervous System Agents; Reproductive Effect; Sensory System Agents; Tumor data

Nitrous oxide History

In the year 1775, Nitrous oxide (CAS NO.10024-97-2) was first synthesized by English chemist and natural philosopher Joseph Priestley,who called it phlogisticated nitrous air. Priestley describes the preparation of "nitrous air diminished" by heating iron filings dampened with nitric acid in Experiments and Observations on Different Kinds of Air (1775).
Humphry Davy in the 1790s tested the gas on himself and some of his friends, including the poet Samuel Taylor Coleridge. They realized that Nitrous oxide (CAS NO.10024-97-2) considerably dulled the sensation of pain, even if the inhaler were still semi-conscious. After it was publicized extensively by Gardner Quincy Colton in the United States in the 1840s, it came into use as an anaesthetic, particularly by dentists, who do not typically have access to the services of an anesthesiologist and who may benefit from a patient who can respond to verbal commands.

Nitrous oxide Uses

Nitrous oxide (CAS NO.10024-97-2) is used in surgery and dentistry for its anesthetic and analgesic effects. It is also used as an oxidizer in rocketry and in motor racing to increase the power output of engines.

Nitrous oxide Production

Nitrous oxide(10024-97-2) is manufactured by heating very pure ammonium nitrate to 200 to 260 °C in aluminum retorts,
NH₄NO₃ → N₂O + 2H₂It is purified by treatment with caustic to remove nitric acid and with dichromate to remove nitric oxide.

Nitrous oxide Toxicity Data With Reference

1.	sln-dmg-ihl 99 pph/6M-C	ENVRAL Environmental Research. 7 (1974),286.
2.	dni-rat-ihl 75,000 ppm/24H AACRAT 62,738,83
3.	ihl-hmn TDLo:24 mg/kg/2H:CNS,CVS,MET	BJANAD British Journal of Anesthesia. 35 (1963),631.
4.	ihl-rat LC50:160 mg/m3/6H	GISAAA Gigiena i Sanitariya. 50 (4)(1985),89.
5.	ihl-rat TCLo:30 mg/m3/6H/61D-I	GISAAA Gigiena i Sanitariya. 50 (4)(1985),89.
6.	ihl-rat TCLo:14 mg/m3/6H/17W-I	GISAAA Gigiena i Sanitariya. 50 (4)(1985),89.
7.	ihl-mus TCLo:50 ppm/6H/13W-I	TXCYAC Toxicology. 6 (1990),57.

Nitrous oxide Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Nitrous oxide Safety Profile

Moderately toxic by inhalation. Human systemic effects by inhalation: general anesthetic, decreased pulse rate without blood pressure fall, and body temperature decrease. An experimental teratogen. Experimental reproductive effects. Mutation data reported. An asphyxiant. Does not burn but is flammable by chemical reaction and supports combustion. Moderate explosion hazard; it can form an explosive mixture with air. Violent reaction with Al, B, hydrazine, LiH, LiC₆H₅, PH₃, Na, tungsten carbide. Also self-explodes at high temperatures.
Hazard Codes: Oxidizing O
Risk Statements: 8
R8: Contact with combustible material may cause fire
Safety Statements: 38
S38: In case of insufficient ventilation, wear suitable respiratory equipment
F: 4.5-31: Do not heat over 50 °C. Do not puncture.
RIDADR: UN 1070 2.2
WGK Germany: 1
HazardClass: 2.2
RTECS: QX1350000

Nitrous oxide Standards and Recommendations

OSHA PEL: OSHA PEL (Shipyard): Simple asphyxiant-inert gas and vapor
ACGIH TLV: 50 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 100 ppm (180 mg/m³)
NIOSH REL: (Waste Anesthetic Gases and Vapors) TWA 25 ppm
DOT Classification: 2.2; Label: Nonflammable Gas

Nitrous oxide Analytical Methods

For occupational chemical analysis use NIOSH: Nitrous Oxide (Field-Readable), 6600.

Nitrous oxide Specification

Nitrous oxide (CAS NO.10024-97-2), its Synonyms are Dinitrogen monoxide ; Dinitrogen oxide ; Hyponitrous acid anhydride ; Laughing gas ; Nitrogen hypoxide ; Nitrogen monoxide ; Nitrous oxide, compressed ; Nitrous oxide, refrigerated liquid ; Oxido nitroso . It is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste.

Product Name

NITROUS OXIDE

Synthetic route

Nitrous oxide Chemical Properties

Nitrous oxide History

Nitrous oxide Uses

Nitrous oxide Production

Nitrous oxide Toxicity Data With Reference

Nitrous oxide Consensus Reports

Nitrous oxide Safety Profile

Nitrous oxide Standards and Recommendations

Nitrous oxide Analytical Methods

Nitrous oxide Specification

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