Product Name

  • Name

    Octadecanamide

  • EINECS 204-693-2
  • CAS No. 124-26-5
  • Article Data54
  • CAS DataBase
  • Density 0.868 g/cm3
  • Solubility 102μg/L at 20℃
  • Melting Point 98-102 °C(lit.)
  • Formula C18H37NO
  • Boiling Point 408.2 °C at 760 mmHg
  • Molecular Weight 283.498
  • Flash Point 207.5 °C
  • Transport Information
  • Appearance light yellow granules
  • Safety 24/25
  • Risk Codes
  • Molecular Structure Molecular Structure of 124-26-5 (Octadecanamide)
  • Hazard Symbols
  • Synonyms Stearamide(6CI,7CI,8CI);Adogen 42;Advawax 290;Alflow S 10;Amide AP;Amide S;Amide S (binder);Amide T;Armid 18;Armoslip 18LF;Atmer SA 1750;Crodamide S;Crodamide SR;Diamid AP 1;EBF;Fatty Amide S;Fatty Amide T;G 270;Hidorin F792;Hidorin M 7;Hymicron G 270;Hymicron L 271;Kao Fatty Amide S;KawaslipVL;Kemamide S;L 271;Lutamide S;NSC 66462;Neutron 2;Neutron 2S;Selosol 2M;Stearic acid amide;Stearic amide;Stearoylamide;Stearoylamine;Stearylamide;Uniwax 1750;Stearamide;
  • PSA 43.09000
  • LogP 6.43350

Synthetic route

stearic acid
57-11-4

stearic acid

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With titanium(IV) isopropylate; ammonia at 165℃; for 7h; Reagent/catalyst; Temperature; Large scale;98.4%
With ammonium bicarbonate; formamide for 0.15h; Irradiation;82%
Stage #1: stearic acid With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 0.5h;
Stage #2: With ammonia In dichloromethane for 12h;
23%
Octadecanoyl-carbamic acid tert-butyl ester
120158-01-2

Octadecanoyl-carbamic acid tert-butyl ester

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane for 1h; Ambient temperature;97%
octadecanoyl azide
77165-65-2

octadecanoyl azide

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With zinc(II) tetrahydroborate In 1,2-dimethoxyethane for 0.5h; Ambient temperature;95%
stearonitrile
638-65-3

stearonitrile

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With N-ethyl-N-hydroxy-ethanamine; water at 100℃; for 5h;90%
With sodium hydroxide; poly(ethylene glycol)-400 for 0.0166667h; microwave irradiation;78%
(i) HCl, SnCl2, Et2O, (ii) H2O; Multistep reaction;
1-aminooctadecane
124-30-1

1-aminooctadecane

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With fluorenone imine; oxygen In toluene for 60h; Reflux;51%
stearic acid ethyl ester
111-61-5

stearic acid ethyl ester

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With ammonia; water at 180℃;
2-hexadecyl-malonamic acid

2-hexadecyl-malonamic acid

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 130 - 150℃;
2-hexadecyl-malonamic acid

2-hexadecyl-malonamic acid

A

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

B

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 130 - 150℃;
(stearoylamino-methylsulfanyl)-acetic acid
102899-77-4

(stearoylamino-methylsulfanyl)-acetic acid

stearamide
124-26-5

stearamide

stearic acid
57-11-4

stearic acid

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 180 - 190℃;
phenyl carbamate
64-10-8

phenyl carbamate

stearic acid
57-11-4

stearic acid

A

N-phenylstearamide
637-54-7

N-phenylstearamide

B

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 160℃;
stearic acid
57-11-4

stearic acid

urea
57-13-6

urea

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 160℃;
With diammonium phosphate at 195℃;
at 160℃;
at 205 - 210℃;
Stearoyl chloride
112-76-5

Stearoyl chloride

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With diethyl ether; ammonia
With ammonia
With ammonia
N-(1-Cyanethyl)-stearoylamid
40652-01-5

N-(1-Cyanethyl)-stearoylamid

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
(thermolysis);
ammonia
7664-41-7

ammonia

stearic acid
57-11-4

stearic acid

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 135 - 200℃; Kinetics;
stearacidic ammonium

stearacidic ammonium

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
at 230℃;
(stearoylamino-methylsulfanyl)-acetic acid
102899-77-4

(stearoylamino-methylsulfanyl)-acetic acid

diluted acid

diluted acid

stearamide
124-26-5

stearamide

stearic acid
57-11-4

stearic acid

zinc stearate

zinc stearate

A

stearamide
124-26-5

stearamide

B

trichloromethyl-chloro formate

trichloromethyl-chloro formate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: SOCl2
2: NH3
View Scheme
N-Boc-octadecylamine
38428-49-8

N-Boc-octadecylamine

A

stearamide
124-26-5

stearamide

B

phenylmercury hydroxide

phenylmercury hydroxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 98 percent / ruthenium dioxide hydrate, 10percent aqueous NaIO4 / ethyl acetate / 3 h / Ambient temperature
2: 97 percent / trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
View Scheme
1-aminooctadecane
124-30-1

1-aminooctadecane

A

stearamide
124-26-5

stearamide

B

phenylmercury hydroxide

phenylmercury hydroxide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / triethylamine / H2O; dioxane / 6 h / Ambient temperature
2: 98 percent / ruthenium dioxide hydrate, 10percent aqueous NaIO4 / ethyl acetate / 3 h / Ambient temperature
3: 97 percent / trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
View Scheme
acetonin
53422-22-3

acetonin

sodium hydrogencarbonate
144-55-8

sodium hydrogencarbonate

Stearoyl chloride
112-76-5

Stearoyl chloride

stearamide
124-26-5

stearamide

dimethyl amine
124-40-3

dimethyl amine

methyl (9Z,12S,13R)-12,13-epoxy-9-octadecenoate
2733-91-7

methyl (9Z,12S,13R)-12,13-epoxy-9-octadecenoate

A

cis-9-octadecenoamide
301-02-0

cis-9-octadecenoamide

B

N,N-dimethyl-(12S,13R)-epoxy-cis-9-octadecenyl amide
1323108-64-0

N,N-dimethyl-(12S,13R)-epoxy-cis-9-octadecenyl amide

C

Palmitamide
629-54-9

Palmitamide

D

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
Stage #1: dimethyl amine; methyl (9Z,12S,13R)-12,13-epoxy-9-octadecenoate With sodium methylate In methanol for 2h; Reflux;
Stage #2: In methanol at 0℃; for 24.25h;
octadecanoyl azide
77165-65-2

octadecanoyl azide

A

octadecyl isocyanate
112-96-9

octadecyl isocyanate

B

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With anthracene at 20℃; Kinetics; Reagent/catalyst; Photolysis;
1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine
933460-58-3

1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine

docosanoyl chloride
21132-76-3

docosanoyl chloride

A

(S,E)-(8-amino-3-(hydroxymethyl)-6,10-dioxo-2-oxa-5,7,9-triazahentriacont-7-en-1-yl)phosphonic acid
1608459-53-5

(S,E)-(8-amino-3-(hydroxymethyl)-6,10-dioxo-2-oxa-5,7,9-triazahentriacont-7-en-1-yl)phosphonic acid

B

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine / 48 h / 20 °C
2: acetonitrile / 24 h / 20 °C
View Scheme
trimethylsilyl bromide
2857-97-8

trimethylsilyl bromide

1-(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)propyl-N4-docosanoyl-5-azacytosine]
1608457-43-7

1-(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)propyl-N4-docosanoyl-5-azacytosine]

A

(S,E)-(8-amino-3-(hydroxymethyl)-6,10-dioxo-2-oxa-5,7,9-triazahentriacont-7-en-1-yl)phosphonic acid
1608459-53-5

(S,E)-(8-amino-3-(hydroxymethyl)-6,10-dioxo-2-oxa-5,7,9-triazahentriacont-7-en-1-yl)phosphonic acid

B

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
In acetonitrile at 20℃; for 24h;
N-methylol stearamide
3370-35-2

N-methylol stearamide

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid methyl ester; sulfuric acid
View Scheme
glycerol tristearate
555-43-1

glycerol tristearate

stearamide
124-26-5

stearamide

Conditions
ConditionsYield
With ammonia at 180℃; for 6h; Autoclave;91 %Chromat.
stearamide
124-26-5

stearamide

stearonitrile
638-65-3

stearonitrile

Conditions
ConditionsYield
With triethylamine; trifluoroacetyl chloride In dichloromethane95%
at 295℃; for 1h; Temperature;86%
With trichloromethyl chloroformate; benzene
stearamide
124-26-5

stearamide

octadecylamine hydrochloride
1838-08-0

octadecylamine hydrochloride

Conditions
ConditionsYield
Stage #1: stearamide With titanium(IV) isopropylate In toluene at 20 - 100℃;
Stage #2: With hydrogenchloride In diethyl ether; toluene
90%
Yield given. Multistep reaction;
[hydroxy(tosyloxy)iodo]benzene
27126-76-7

[hydroxy(tosyloxy)iodo]benzene

stearamide
124-26-5

stearamide

heptadecylammonium p-toluenesulfonate
67038-06-6

heptadecylammonium p-toluenesulfonate

Conditions
ConditionsYield
In acetonitrile at 65 - 70℃; for 0.0333333h;89.5%
stearamide
124-26-5

stearamide

polystyrene, linear, with -I(OH)OSO2C6H4-CH3-p groups

polystyrene, linear, with -I(OH)OSO2C6H4-CH3-p groups

heptadecylammonium p-toluenesulfonate
67038-06-6

heptadecylammonium p-toluenesulfonate

Conditions
ConditionsYield
In acetonitrile for 2h; Heating;89%
benzyl alcohol
100-51-6

benzyl alcohol

stearamide
124-26-5

stearamide

benzyl stearate
5531-65-7

benzyl stearate

Conditions
ConditionsYield
With cerium(IV) oxide In 1,3,5-trimethyl-benzene at 165℃; for 22h; Inert atmosphere;86%
stearamide
124-26-5

stearamide

stearic acid
57-11-4

stearic acid

Conditions
ConditionsYield
With niobium(V) oxide; water In neat (no solvent) for 20h; Reflux; Inert atmosphere;86%
stearamide
124-26-5

stearamide

n-Octadecanal
638-66-4

n-Octadecanal

Conditions
ConditionsYield
With lithium-tris(diethylamino)hydridoaluminate In tetrahydrofuran for 12h; Ambient temperature;83%
Multi-step reaction with 2 steps
1: thionyl chloride
2: tin (II)-chloride; hydrogen chloride; diethyl ether / und beim Verseifen des Reaktionsprodukts mit warmem Wasser
View Scheme
4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

stearamide
124-26-5

stearamide

N-(4-nitrobenzoyl)stearamide
1109247-32-6

N-(4-nitrobenzoyl)stearamide

Conditions
ConditionsYield
Stage #1: 4-nitrobenzaldehdye; stearamide With copper(I) bromide In tetrachloromethane; acetonitrile at 20℃; for 0.25h; Inert atmosphere;
Stage #2: With N-Bromosuccinimide In tetrachloromethane; acetonitrile at 90℃; for 15h; Inert atmosphere;
80%
Dimethyl-p-toluidine
99-97-8

Dimethyl-p-toluidine

stearamide
124-26-5

stearamide

C27H48N2O

C27H48N2O

Conditions
ConditionsYield
With tert.-butylhydroperoxide; copper(I) bromide In decane at 80℃; for 6h;78%
leelamine
1446-61-3

leelamine

stearamide
124-26-5

stearamide

(+)-N-(stearoyl)-dehydroabietylamine

(+)-N-(stearoyl)-dehydroabietylamine

Conditions
ConditionsYield
Stage #1: stearamide With borane tetrahydrofuran In toluene at 0 - 20℃; for 1h;
Stage #2: leelamine In toluene Reflux;
77.68%
cis,trans-2,5-dimethoxytetrahydrofuran
696-59-3

cis,trans-2,5-dimethoxytetrahydrofuran

stearamide
124-26-5

stearamide

A

1-Pyrrol-1-yl-octadecan-1-one
86734-18-1

1-Pyrrol-1-yl-octadecan-1-one

B

stearonitrile
638-65-3

stearonitrile

Conditions
ConditionsYield
With phosphorus pentoxide In toluene at 60 - 110℃; for 1.25h;A 75%
B 25%
ethanolamine
141-43-5

ethanolamine

stearamide
124-26-5

stearamide

N-stearoylethanolamine
111-57-9

N-stearoylethanolamine

Conditions
ConditionsYield
Stage #1: stearamide With triethylamine; methyl chloroformate In dichloromethane at 0 - 20℃; for 2h;
Stage #2: ethanolamine In dichloromethane at 0 - 20℃; for 20h;
74%
1,4-dichloro-1,4-dimethoxybutane
86428-38-8

1,4-dichloro-1,4-dimethoxybutane

stearamide
124-26-5

stearamide

1-Pyrrol-1-yl-octadecan-1-one
86734-18-1

1-Pyrrol-1-yl-octadecan-1-one

Conditions
ConditionsYield
With Amberlyst A-21 resin In acetonitrile at 55℃; for 16h;72%
phenyl-λ3-iodanediyl bis(3-phenylpropanoate)

phenyl-λ3-iodanediyl bis(3-phenylpropanoate)

stearamide
124-26-5

stearamide

N-heptadecyl-3-phenylpropanamide

N-heptadecyl-3-phenylpropanamide

Conditions
ConditionsYield
In 1,2-dichloro-ethane at 100℃; for 24h;71%
trimethyl phosphite
512-56-1

trimethyl phosphite

stearamide
124-26-5

stearamide

N-methylstearylamide
20198-92-9

N-methylstearylamide

Conditions
ConditionsYield
With n-butyllithium; cyclopentyl methyl ether In hexane at 115℃; for 24h; Reagent/catalyst; Inert atmosphere;65%
Diphenylmethane
101-81-5

Diphenylmethane

stearamide
124-26-5

stearamide

N-benzhydrylstearamide

N-benzhydrylstearamide

Conditions
ConditionsYield
With N-Bromosuccinimide; copper(I) bromide In ethyl acetate at 50℃; for 12h;42%
4-bromo-N,N-dimethylaniline
586-77-6

4-bromo-N,N-dimethylaniline

stearamide
124-26-5

stearamide

C26H45BrN2O
1042709-60-3

C26H45BrN2O

Conditions
ConditionsYield
With N-chloro-succinimide; copper(I) bromide In ethyl acetate at 25℃; for 6h;42%
2-Oxobutyric acid
600-18-0

2-Oxobutyric acid

stearamide
124-26-5

stearamide

(Z)-2-Octadecanoylamino-but-2-enoic acid

(Z)-2-Octadecanoylamino-but-2-enoic acid

Conditions
ConditionsYield
In toluene Heating;25%
pyrrolidinylmethanol
20789-05-3

pyrrolidinylmethanol

stearamide
124-26-5

stearamide

N-pyrrolidinomethyl-stearamide

N-pyrrolidinomethyl-stearamide

Conditions
ConditionsYield
at 150℃;
pyridine
110-86-1

pyridine

phosgene
75-44-5

phosgene

toluene
108-88-3

toluene

stearamide
124-26-5

stearamide

stearoyl-carbamoyl chloride

stearoyl-carbamoyl chloride

Conditions
ConditionsYield
at 150℃;
9-hydroxyxanthene
90-46-0

9-hydroxyxanthene

stearamide
124-26-5

stearamide

N-xanthen-9-yl-stearamide
6325-90-2

N-xanthen-9-yl-stearamide

Conditions
ConditionsYield
With acetic acid
With acetic acid

Octadecanamide Chemical Properties

EINECS: 204-693-2
Molecular Formula: C18H37NO
Molecular Weight: 283.49 
Nominal Mass: 283 Da
Average Mass: 283.4925 Da
Monoisotopic Mass: 283.287515 Da 
Index of Refraction: 1.457
Molar Refractivity: 89 cm3
Molar Volume: 326.4 cm3
Surface Tension: 32.9 dyne/cm
Density: 0.868 g/cm3
Flash Point: 207.5 °C
Enthalpy of Vaporization: 66.02 kJ/mol
Boiling Point: 408.2 °C at 760 mmHg
Vapour Pressure: 7.11E-07 mmHg at 25 °C
Melting Point: 98-102 °C(lit.)
Appearance: Light yellow granules
Structure of Octadecanamide (CAS NO.124-26-5):
                                    
IUPAC Name: Octadecanamide
Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)N
InChI: InChI=1S/C18H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H2,19,20)
InChIKey: LYRFLYHAGKPMFH-UHFFFAOYSA-N
Product Category of Octadecanamide (CAS NO.124-26-5): Color Former & Related Compounds;Functional Materials;Sensitizer

Octadecanamide Uses

 Octadecanamide (CAS NO.124-26-5) is commonly used as smoothness agent and release agent for PVC, polyolefin, polystyrene and other plastics.

Octadecanamide Toxicity Data With Reference

 Octadecanamide (CAS NO.124-26-5) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. You can see actual entry in RTECS for complete information. The toxicological properties have not been fully investigated.

Octadecanamide Consensus Reports

Reported in EPA TSCA Inventory.

Octadecanamide Safety Profile

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
Safety Statements: 22-24/25 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes.
WGK Germany: 1

Octadecanamide Specification

 Octadecanamide , its cas register number is 124-26-5. It also can be called Stearamide ; Kemamide S ; and Stearylamide .It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. While, it's inhaled: Remove from exposure and move to fresh air immediately. Then you have the ingesting of the product : Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
In addition,  Octadecanamide (CAS NO.124-26-5) is not compatible with strong oxidizing agents, strong acids, and you must not take it with incompatible materials. It should be exposured to moist air or water. And also prevent it to broken down into hazardous decomposition products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View