Conditions | Yield |
---|---|
With potassium hydroxide; ethanol |
Conditions | Yield |
---|---|
at 700℃; | |
at 900℃; |
Conditions | Yield |
---|---|
anschl. Gluehen; | |
anschl. Gluehen; |
Conditions | Yield |
---|---|
Schmelzen mit viel Kalium; |
Conditions | Yield |
---|---|
beim Schmelzen; |
2,6-diethyl-5-methyl-3H-pyrimidin-4-one
A
ammonia
B
potassium cyanide
C
acetic acid
D
propionic acid
Conditions | Yield |
---|---|
beim Schmelzen; |
Conditions | Yield |
---|---|
im bedeckten Tiegel; |
methyl thiocyanate
A
Dimethyldisulphide
B
ammonia
C
potassium cyanide
dipicryl-diazene
A
potassium cyanide
B
2,4,6-Trinitrophenol
C
2,2',4,4',6,6'-hexanitrohydrazobenzene
Conditions | Yield |
---|---|
in der Rotglut; |
ethyl isothiocyanate
A
Diethyl disulfide
B
potassium cyanate
C
potassium cyanide
Conditions | Yield |
---|---|
at 100℃; im zugeschmolzenen Rohr; |
Cyan-imidoameisensaeureethylester
A
potassium cyanide
Conditions | Yield |
---|---|
at 80℃; |
ethanedinitrile
A
potassium cyanate
B
ammonia
C
potassium cyanide
Conditions | Yield |
---|---|
Produkt5: CO2; |
ethanedinitrile
A
potassium cyanate
B
carbon dioxide
C
potassium cyanide
Conditions | Yield |
---|---|
at 190 - 370℃; Produkt 5: Stickstoff; |
Conditions | Yield |
---|---|
Sucrose-ethyleneoxide adducts In acetonitrile at 83℃; for 24h; Product distribution; further catalysts: PEG, DB18K6; further objects of study: phase-transfer catalysis; further solvents: toluene/H2O; | 100% |
tetraoctyl ammonium bromide In water; toluene at 90℃; for 24h; Product distribution; other phase-transfer catalysts, time; | 99% |
tetraoctyl ammonium bromide In water; toluene at 90℃; for 24h; | 99% |
Conditions | Yield |
---|---|
Stage #1: potassium cyanide; acetophenone With 18-crown-6 ether In dichloromethane at 20℃; for 4h; Stage #2: With hydrogenchloride In tetrahydrofuran; dichloromethane at 0 - 20℃; for 2h; | 100% |
Stage #1: potassium cyanide; acetophenone With tetrachlorosilane In acetonitrile at 60 - 70℃; for 5h; Stage #2: With sodium hydrogencarbonate In water; acetonitrile Further stages.; | 82% |
With hydrogenchloride |
potassium cyanide
1-bromomethyl-3-trifluoromethylbenzene
3-trifluoromethylphenylacetonitrile
Conditions | Yield |
---|---|
In ethanol; water for 1.5h; Heating / reflux; | 100% |
In dimethyl sulfoxide |
3-pyridinecarboxaldehyde
potassium cyanide
2-hydroxy-2-(pyridin-3-yl)acetonitrile
Conditions | Yield |
---|---|
With water; acetic acid at 5 - 10℃; for 2h; | 100% |
With hydrogenchloride | |
With acetic acid In water for 18h; Ambient temperature; |
chloro-trimethyl-silane
6-methoxy-2-acetylnaphthalene
potassium cyanide
2-(6-methoxy-2-naphthyl)-2-(trimethylsilyloxy)propiononitrile
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 60℃; for 13.5h; | 100% |
(+)-<(1S,2S)-1-Hydroxy-2-methyl-3-oxo-cyclopent-2-yl>-essigsaeure-γ-lacton
potassium cyanide
(1S,2S)-6-Cyano-6-hydroxy-5-methyl-2-oxa-bicyclo<3.3.0>octan-3-on
Conditions | Yield |
---|---|
In water; acetic acid at 5℃; for 20h; | 100% |
Octanal
methylamine hydrochloride
potassium cyanide
2-Methylamino-nonanenitrile
Conditions | Yield |
---|---|
With aluminum oxide In acetonitrile at 50℃; for 22h; ultrasound; | 100% |
5-anti-Chloro-6-syn-cyanobicyclo<2.1.1>hexene
potassium cyanide
endo,endo-3,5-Dicyanotricyclo<2.2.0.02.6>hexane
Conditions | Yield |
---|---|
In water; acetonitrile for 30h; Ambient temperature; | 100% |
9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-one
potassium cyanide
2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2-carbonitrile
Conditions | Yield |
---|---|
With ammonia; acetic acid In water at 40℃; for 25h; Irradiation; irrad. with ultrasound; | 100% |
potassium cyanide
7-methoxy-1,4,4-trimethylisothiochroman-1-ylacetonitril
Conditions | Yield |
---|---|
In ethanol; water for 3h; Heating; | 100% |
Conditions | Yield |
---|---|
Sucrose-ethyleneoxide adducts In acetonitrile at 20℃; for 8h; Product distribution; further catalysts: PEG, DB18K6; further objects of study: phase-transfer catalysis; further solvents: toluene/H2O; | 100% |
With water; Aliquat 336 for 2h; Ambient temperature; | 97% |
With poly(ethylene glycol)-supported tetrabutylamminium bromide In water at 25℃; for 2h; Substitution; | 97% |
potassium cyanide
aniline hydrochloride
4-fluorobenzaldehyde
2-(4-fluorophenyl)-2-(phenylamino) acetonitrile
Conditions | Yield |
---|---|
In ethanol; water 1.) 1 h cooling; 2.) 20 h room temperature; | 100% |
potassium cyanide
Conditions | Yield |
---|---|
In methanol at 0℃; for 0.25h; | 100% |
potassium cyanide
Conditions | Yield |
---|---|
In methanol at 0℃; for 0.25h; | 100% |
potassium cyanide
Conditions | Yield |
---|---|
In methanol at 0℃; for 0.25h; | 100% |
potassium cyanide
ethyl [L-(trans)]-4-[(t-butoxycarbonyl)amino]-2-pentenoate
Conditions | Yield |
---|---|
With 18-crown-6 ether In acetonitrile for 24h; Ambient temperature; | 100% |
potassium cyanide
2-Benzyl-3-(bromomethyl)-1,4-dimethoxynaphthalene
2-Benzyl-3-(cyanomethyl)-1,4-dimethoxynaphthalene
Conditions | Yield |
---|---|
In 1,4-dioxane; water for 10h; Heating; | 100% |
potassium cyanide
trans-1-iodo-2-isothiocyanatocyclohexane
2-cyano-cis-3a,4,5,6,7,7a-hexahydrobenzothiazole
Conditions | Yield |
---|---|
With 18-crown-6 ether In chloroform; water for 92h; Heating; | 100% |
potassium cyanide
4'-(chloromethyl)dispirobis<1,3>dioxole-6',1''-cyclohexane>
dispirobis<1,3>dioxole-6',1''-cyclohexane>-4'-acetonitrile
Conditions | Yield |
---|---|
With 18-crown-6 ether In acetonitrile for 5h; Heating; | 100% |
potassium cyanide
diethyl <<3-(bromomethyl)phenyl>methyl>phosphonate
diethyl <<3-(cyanomethyl)phenyl>methyl>phosphonate
Conditions | Yield |
---|---|
With sodium iodide In water; acetone at 50℃; for 48h; | 100% |
potassium cyanide
4-(diethoxyphosphorylmethyl)-1-bromomethyl-phenyl
diethyl <<4-(cyanomethyl)phenyl>methyl>phosphonate
Conditions | Yield |
---|---|
With sodium iodide In water; acetone at 50℃; for 48h; | 100% |
potassium cyanide
Conditions | Yield |
---|---|
In water | 100% |
potassium cyanide
Conditions | Yield |
---|---|
In methanol at 0℃; for 0.25h; | 100% |
potassium cyanide
Conditions | Yield |
---|---|
With ammonium chloride In water; N,N-dimethyl-formamide at 100℃; for 4.5h; | 100% |
potassium cyanide
acetaldehyde
2-amino-1-phenylpropane
2-<(1-methyl-2-phenylethyl)amino>propanenitrile
Conditions | Yield |
---|---|
With sodium hydrogensulfite In methanol; water Ambient temperature; | 100% |
methylamine hydrochloride
potassium cyanide
acetophenone
2-methylamino-2-phenyl-propionitrile
Conditions | Yield |
---|---|
With aluminum oxide In acetonitrile at 50℃; for 24h; ultrasound; | 100% |
Conditions | Yield |
---|---|
Stage #1: 3-methoxy-benzaldehyde With hydrogenchloride; sodium sulfite In tetrahydrofuran; water at 20℃; for 0.166667h; Stage #2: potassium cyanide In tetrahydrofuran; water for 0.5h; | 100% |
With sodium hydrogensulfite 1) H2O, 40 deg C, 0.5 h, 2) H2O, 0 deg C, 1 h; Multistep reaction; | |
With acetic acid In water | |
With hydrogenchloride; sodium sulfite In tetrahydrofuran at 20℃; for 0.5h; |
formaldehyd
potassium cyanide
benzyl-methyl-amine
(N-benzyl-N-methylamino)acetonitrile
Conditions | Yield |
---|---|
With hydrogenchloride for 16h; Ambient temperature; | 100% |
potassium cyanide
Conditions | Yield |
---|---|
With acetic acid In methanol; isopropyl alcohol | 100% |
(2Z)-3-methyl-2-penten-4-ynal
potassium cyanide
Conditions | Yield |
---|---|
With hydrogenchloride In diethyl ether; water 30 min, 0 deg C; 2 h, 20 deg C; | 100% |
The IUPAC name of Potassium cyanide is potassium cyanide. With the CAS registry number 151-50-8, it is also named as Hydrocyanic acid, potassium salt. The product's categories are Inorganics; ACS Grade; Essential Chemicals; Routine Reagents; Masking AgentsAnalytical Reagents for General Use; Complexometric Titration (IDRANAL); O-P, Puriss p.a. ACS; Puriss p.a. ACS; Titration; Masking Agents; O-P, Puriss p.a.; Puriss p.a., and the other registry numbers are 133708-36-8; 15745-74-1; 60195-52-0. Besides, it is white granular powder or crystals, which should be sealed in a cool and dry warehouse. In addition, its molecular formula is CKN and molecular weight is 65.12.
The other characteristics of this product can be summarized as: (1)EINECS: 205-792-3; (2)H-Bond Donor: 0; (3)H-Bond Acceptor: 2; (4)Rotatable Bond Count: 0; (5)Exact Mass: 64.966781; (6)MonoIsotopic Mass: 64.966781; (7)Topological Polar Surface Area: 23.8; (8)Heavy Atom Count: 3; (9)Complexity: 12.8; (10)Density: 1.52 g/cm3; (11)Melting point: 634.5 °C; (12)Boiling point: 1625 °C; (13)Flash Point: 1625 °C; (14)Solubility in water: 71.6 g/100 ml (25 °C).
Preparation of Potassium cyanide: this chemical can be prepared by the treatment of Hydrogen cyanide with Potassium hydroxide:
HCN + KOH → KCN + H2O
Uses of Potassium cyanide: it is widely used in organic synthesis for the preparation of nitriles and carboxylic acids. It is also used in electroplating, such as jewelry for chemical gilding and buffing. And this product has been used as a killing agent in collecting jars by entomologists. Additionally, this chemical can form water-soluble salts from gold metal in the presence of air in gold mining:
4 Au + 8 KCN + O2 + 2 H2O → 4 K[Au(CN)2] + 4 KOH
When you are using this chemical, please be cautious about it as the following: it is very toxic by inhalation, in contact with skin and if swallowed. And it would liberate very toxic gas in contact with acid. Please keep container tightly closed and do not empty into drains. After contact with skin, you should wash immediately with plenty of soap-suds. Moreover, it is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) And this material and its container must be disposed of as hazardous waste. Please avoid release to the environment and refer to special instructions / safety data sheets.
People can use the following data to convert to the molecule structure.
(1)Canonical SMILES: [C-]#N.[K+]
(2)InChI: InChI=1S/CN.K/c1-2;/q-1;+1
(3)InChIKey: NNFCIKHAZHQZJG-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | intravenous | 2200ug/kg (2.2mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 316, 1936. | |
dog | LD50 | subcutaneous | 6mg/kg (6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archiv fuer Toxikologie. Vol. 21, Pg. 89, 1965. |
dog | LDLo | intravenous | 5mg/kg (5mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
frog | LDLo | subcutaneous | 60mg/kg (60mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. | |
guinea pig | LDLo | intraarterial | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | intraperitoneal | 8mg/kg (8mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927. | |
guinea pig | LDLo | intravenous | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | subcutaneous | 8mg/kg (8mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927. | |
human | LDLo | oral | 2857ug/kg (2.857mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 191, 1969. | |
man | TDLo | oral | 13699ug/kg (13.699mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA | Journal of Toxicology, Clinical Toxicology. Vol. 25, Pg. 121, 1987. |
mouse | LD50 | intraperitoneal | 5991ug/kg (5.991mg/kg) | Pesticide Biochemistry and Physiology. Vol. 2, Pg. 95, 1972. | |
mouse | LD50 | intravenous | 2600ug/kg (2.6mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
mouse | LD50 | oral | 8500ug/kg (8.5mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 161, Pg. 163, 1968. | |
mouse | LD50 | subcutaneous | 6500ug/kg (6.5mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 1057, 1958. | |
pigeon | LD50 | intramuscular | 4mg/kg (4mg/kg) | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. | |
rabbit | LD50 | intramuscular | 3256ug/kg (3.256mg/kg) | Journal of the American College of Toxicology. Vol. 1(3), Pg. 120, 1982. | |
rabbit | LD50 | intraperitoneal | 3972ug/kg (3.972mg/kg) | BLOOD: OTHER CHANGES | Toxicologist. Vol. 3, Pg. 64, 1983. |
rabbit | LD50 | ocular | 7870ug/kg (7.87mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 2, Pg. 119, 1983. |
rabbit | LD50 | oral | 5mg/kg (5mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
rabbit | LD50 | subcutaneous | 4mg/kg (4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
rat | LD50 | intraperitoneal | 4mg/kg (4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Applied Physiology. Vol. 32, Pg. 315, 1972. |
rat | LD50 | intravenous | 3600ug/kg (3.6mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Drug Development Research. Vol. 5, Pg. 225, 1985. |
rat | LD50 | oral | 5mg/kg (5mg/kg) | Archives of Toxicology. Vol. 54, Pg. 275, 1983. | |
rat | LD50 | subcutaneous | 7814ug/kg (7.814mg/kg) | Archives of Toxicology, Supplement. Vol. 14, Pg. 231, 1991. | |
rat | LDLo | intramuscular | 8mg/kg (8mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
women | TDLo | oral | 100mg/kg (100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | American Journal of Emergency Medicine. Vol. 1, Pg. 94, 1983. |
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