• Name

  Potassium phthalimide

• EINECS 214-046-6
• CAS No. 1074-82-4
• Article Data29
• CAS DataBase
• Density 1.367 g/cm³
• Solubility Soluble in water.
• Melting Point >300 ºC
• Formula C₈H₄KNO₂
• Boiling Point 359 ºC at 760 mmHg
• Molecular Weight 187.239
• Flash Point 170.9 ºC
• Transport Information
• Appearance greenish white powder
• Safety 22-24/25-26
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms 1H-Isoindole-1,3(2H)-dione,potassium salt (9CI);Phthalimide, potassium deriv. (6CI);Phthalimide,potassium salt (8CI);Potassium, phthalimido- (7CI);N-Potassiophthalimide;Phthalimide potassium;Phthalimidopotassium;Potassium isoindoline-1,3-dione;Potassium phthalimidate;1H-Isoindole-1,3(2H)-dione,potassium salt (1:1);
• PSA 34.14000
• LogP 0.68480

Synthetic route

136918-14-4

phthalimide

1074-82-4

potassium phtalimide

Conditions

Conditions	Yield
With potassium methanolate In ethanol; water at 60 - 65℃; for 13h; Reagent/catalyst; Solvent; Temperature;	98%
With potassium hydroxide In ethanol at 75℃; for 1h;	96%
With potassium hydroxide In ethanol for 2h;	91.5%

3416-57-7

N-acetonylphthalimide

aqueous-alcoholic KOH-solution

aqueous-alcoholic KOH-solution

1074-82-4

potassium phtalimide

40794-76-1

C9H4NO4(1-)*K(1+)

A

124-38-9

carbon dioxide

B

1074-82-4

potassium phtalimide

Conditions

Conditions	Yield
With nitrogen at 65℃; for 0.666667h;

7252-83-7

1-bromo-2,2-dimethoxyethane

1074-82-4

potassium phtalimide

27328-34-3

2-(2,2-dimethoxyethyl)-1H-isoindole-1,3(2H)-dione

Conditions

Conditions	Yield
With acetamide; potassium iodide at 110 - 140℃; for 3.41667h;	100%
In N,N-dimethyl-formamide at 130 - 135℃; for 20h;	56%
With acetamide at 170℃;
With acetamide; potassium iodide at 130℃; for 5h;

5414-21-1

5-bromopentan-1-nitrile

1074-82-4

potassium phtalimide

15102-28-0

5-(1,3-dioxoisoindolin-2-yl)pentanenitrile

Conditions

Conditions	Yield
In DMF (N,N-dimethyl-formamide) at 60℃; for 16h;	100%
With ethanol at 120℃;
With N,N-dimethyl-formamide
In N,N-dimethyl-formamide

100-44-7

benzyl chloride

1074-82-4

potassium phtalimide

2142-01-0

N-benzylphthalimide

Conditions

Conditions	Yield
With 18-crown-6 ether In toluene at 100℃; for 6h;	100%
at 180℃;
With Amberlyst A27 In toluene at 90℃; for 17h;	100 % Chromat.

1074-82-4

potassium phtalimide

1119-51-3

bromopentene

7736-25-6

2-(pent-4-enyl)-isoindoline-1,3-dione

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 60℃; for 16h; Gabriel synthesis; Inert atmosphere;	100%
In N,N-dimethyl-formamide at 60℃; for 16h; Inert atmosphere;	100%
In N,N-dimethyl-formamide at 60℃; Inert atmosphere;	99%

1074-82-4

potassium phtalimide

626-87-9

1,4-dibromopentane

59353-62-7

4-bromo-1-phthalimidopentane

Conditions

Conditions	Yield
In 1,1,1-trichloroethane at 60℃; for 24h;	100%
In acetone for 24h; Reflux;	99%
In acetone for 72h; Reflux;	91%

1074-82-4

potassium phtalimide

589-15-1

1-bromomethyl-4-bromobenzene

153171-22-3

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 6h;	100%
In N,N-dimethyl-formamide at 120℃; for 15h; Inert atmosphere;	82%
at 200℃;

1074-82-4

potassium phtalimide

98-59-9

p-toluenesulfonyl chloride

27722-45-8

N-(4-methylbenzenesulphonyl)phthalimide

Conditions

Conditions	Yield
With 18-crown-6 ether In benzene at 70℃; for 1h;	100%
With 18-crown-6 ether In toluene at 90℃; for 1h;	100%
In acetonitrile for 48h; Reflux;	73%
at 140℃;
In acetonitrile Reflux;

1074-82-4

potassium phtalimide

939-26-4

2-bromomethylnaphthyl bromide

247570-26-9

2-[(2-naphthyl)methyl]-1H-isoindole-1,3(2H)-dione

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 120℃; for 15h; Inert atmosphere;	100%
at 180℃;
In N,N-dimethyl-formamide Alkylation;
With tetra-(n-butyl)ammonium iodide In dimethyl sulfoxide for 5h;
In N,N-dimethyl-formamide at 50℃; for 2h;

1074-82-4

potassium phtalimide

2687-12-9

cinnamyl chloride

17480-07-8

2-[(E)-3-phenylprop-2-enyl]-2,3-dihydro-1H-isoindole-1,3-dione

Conditions

Conditions	Yield
potassium iodide In N,N-dimethyl-formamide at 85 - 90℃; for 8h;	100%
at 160℃;

1074-82-4

potassium phtalimide

100-11-8

1-bromomethyl-4-nitro-benzene

62133-07-7

2-(4-nitrobenzyl)-1H-isoindole-1,3(2H)-dione

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 2h;	100%
In N,N-dimethyl-formamide	99%
In N,N-dimethyl-formamide	99%

117-80-6

2,3-Dichloro-1,4-naphthoquinone

1074-82-4

potassium phtalimide

83167-46-8

2,2'-(1,4-dioxo-1,4-dihydronaphthalene-2,3-diyl)bis(isoindoline-1,3-dione)

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 3h; Inert atmosphere; Reflux;	100%
In acetonitrile at 85℃; for 3h;	97%
In acetonitrile at 85℃; for 3h;	97%

74-96-4

ethyl bromide

1074-82-4

potassium phtalimide

5022-29-7

N-ethylphthalimide

Conditions

Conditions	Yield
[2.2.2]cryptande In tetrahydrofuran for 0.00833333h;	100%
In N,N-dimethyl-formamide Heating;	88%
With tetrabutylammomium bromide; silica gel for 0.0666667h; microwave irradiation;	76%

78-77-3

Isobutyl bromide

1074-82-4

potassium phtalimide

304-17-6

N-isopropylphthalimide

Conditions

Conditions	Yield
[2.2.2]cryptande In tetrahydrofuran for 0.25h;	100%

30264-74-5

N-methyl p-chloro-α-chloroacetanilide

1074-82-4

potassium phtalimide

33280-19-2

N-phthalimide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 60 - 75℃; for 2h; room temp. overnight;	100%

68039-14-5

5-acetylamino-4-methoxy-toluene-2-sulfonyl chloride

1074-82-4

potassium phtalimide

N-(2-methyl-4-acylamino-5-methoxybenzenesulphonyl)phthalimide

Conditions

Conditions	Yield
With 18-crown-6 ether In toluene at 85℃; for 0.833333h;	100%

Potassium phthalimide Chemical Properties

Potassium phthalimide Uses

Potassium phthalimide Safety Profile