Pyridoxal phosphate supplier

Name
Pyridoxal phosphate
EINECS 200-208-3
CAS No. 54-47-7
Article Data44
CAS DataBase
Density 1.638 g/cm³
Solubility
Melting Point 140-143 °C
Formula C₈H₁₀NO₆P
Boiling Point 565.746 °C at 760 mmHg
Molecular Weight 247.144
Flash Point 295.952 °C
Transport Information
Appearance Light yellow powder.
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Pyridoxalphosphate (6CI);Pyridoxal, 5-(dihydrogen phosphate) (8CI);2-Methyl-3-hydroxy-4-formyl-5-pyridylmethylphosphoricacid;3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate;Apolon B6;Biosechs;Codecarboxylase;Coenzyme B6;Hairoxal;Hexermin P;Hi-Pyridoxin;Hiadelon;NSC 82388;PAL-P;
PSA 126.76000
LogP 0.51740

Synthetic route

: 65-22-5
pyridoxal hydrochloride

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
Stage #1: pyridoxal hydrochloride With N,N-dimethylethylenediamine In 5,5-dimethyl-1,3-cyclohexadiene at 90℃; for 8h; Stage #2: With polyphosphoric acid at 70℃; for 12h; Solvent;	76%
With water; trichlorophosphate In tetrahydrofuran at 0 - 20℃; for 5h; Reagent/catalyst; Solvent; Temperature;

: 15847-87-7
Phosphoric acid mono-(4-{[(Z)-4-ethoxy-phenylimino]-methyl}-5-hydroxy-6-methyl-pyridin-3-ylmethyl) ester

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With sodium hydroxide at 35℃; for 2h;	68.4%

: 529-96-4
pyridoxamine-5'-phosphate

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With manganese(IV) oxide; Celite in schwach saurer wss.Loesung;
With manganese(IV) oxide; sulfuric acid; water at 70℃;
With copper(II) sulfate; 2-oxo-propionic acid in wss.Loesung;
With copper diacetate; 2-oxo-propionic acid in wss.Loesung;

: 447-05-2
5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With manganese(IV) oxide; sulfuric acid; water at 70℃;

: 66-72-8
pyridoxal

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With water; trichlorophosphate

: triphosphoric acid-1-(4-{[(N,N-dimethyl-glycyl)-hydrazono]-methyl}-5-hydroxy-6-methyl-[3]pyridylmethyl ester)

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With hydrogenchloride; silver(I) nitrite; water at 100℃;

: 1499-44-1
pyridoxalphosphate

A: 54-47-7
pyridoxal 5'-phosphate

B: 56-40-6
glycine

Conditions

Conditions	Yield
In water at 25℃; Equilibrium constant; Mechanism; over a wide pH range;
at 19.99℃; pH=7.35; Equilibrium constant; aq. phosphate buffer;

: 10524-83-1
C14H23N2O5P

A: 111-26-2
hexan-1-amine

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With water at 25℃; Rate constant; also in var. H2O-dioxane solutions; var. pH's;

: 96594-16-0
6-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(Z)-ylidene]-amino}-hexanoic acid

A: 54-47-7
pyridoxal 5'-phosphate

B: 60-32-2
6-aminohexanoic acid

Conditions

Conditions	Yield
In water at 25℃; Equilibrium constant; Mechanism; over a wide pH range;

: 133156-44-2
2-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(Z)-ylidene]-amino}-4-methyl-pentanoic acid

A: 61-90-5
L-leucine

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
In water at 25℃; Equilibrium constant; Mechanism; over a wide pH range;

: 80995-96-6
(2S,3S)-2-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(Z)-ylidene]-amino}-3-methyl-pentanoic acid

A: 73-32-5
L-isoleucine

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
In water at 25℃; Equilibrium constant; Mechanism; over a wide pH range;
With phosphate buffer; Carbonate buffer at 25℃; Equilibrium constant; var. pH;

: 10524-83-1
Phosphoric acid mono-{4-[(Z)-hexyliminomethyl]-5-hydroxy-6-methyl-pyridin-3-ylmethyl} ester

A: 111-26-2
hexan-1-amine

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With pH = 3.6, I = 0.1 In water at 25℃; Equilibrium constant;

: 133156-44-2
(S)-2-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(Z)-ylidene]-amino}-4-methyl-pentanoic acid

A: 61-90-5
L-leucine

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With water Rate constant; Equilibrium constant; dependence on pH, also in the presence of cetyltrimethylammonium bromide;
With phosphate buffer; Carbonate buffer at 25℃; Equilibrium constant; var. pH;

: 83825-03-0
Phosphoric acid mono-(4-{[(Z)-(S)-1-dodecylcarbamoyl-ethylimino]-methyl}-5-hydroxy-6-methyl-pyridin-3-ylmethyl) ester

A: 54-47-7
pyridoxal 5'-phosphate

B: 110139-25-8
N-Dodecyl-(S)-alaninamide

Conditions

Conditions	Yield
With phosphate buffer; ethanol; potassium chloride In 1,4-dioxane; water at 30℃; Equilibrium constant; also in the presence of CTAB, N,N-ditetradecyl-Nα-(6-trimethylammoniohexanoyl)-L-histidinamide bromide and N,N-ditetradecyl-Nα-(6-trimethyammoniohexanoyl)-L-alaninamide bromide;

: (S)-2-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(E)-ylidene]-amino}-propionic acid

A: 56-41-7
L-alanin

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With phosphate buffer; Carbonate buffer at 25℃; Equilibrium constant; var. pH;
at 19.99℃; pH=7.35; Equilibrium constant; aq. phosphate buffer;

: 53-91-8
{3-hydroxy-4-[(E)-(isonicotinoylhydrazono)methyl]-2-methylpyridin-5-yl}methylphosphate

A: 54-85-3
isoniazid

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
at 25℃; Equilibrium constant; Rate constant; depending on pH;

: Phosphoric acid mono-[5-hydroxy-6-methyl-4-(phthalazin-1-yl-hydrazonomethyl)-pyridin-3-ylmethyl] ester

A: 1044569-46-1
1-hydrazinophthalazine

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
at 25℃; Equilibrium constant; Rate constant; depending on pH;

: (S)-3-(3,4-Dihydroxy-phenyl)-2-{N'-[1-(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(E)-ylidene]-hydrazino}-2-methyl-propionic acid

A: 54-47-7
pyridoxal 5'-phosphate

B: 302-53-4, 14585-65-0, 28860-95-9, 28875-92-5
S(-)-carbidopa

Conditions

Conditions	Yield
at 25℃; Equilibrium constant; Rate constant; depending on pH;

: 72343-06-7
(E)-N'-((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)benzohydrazide

metaphosphoric acid: metaphosphoric acid

: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
at 60℃; und Erwaermen des Reaktionsprodukts mit wss.Salzsaeure und Silbernitrit auf 100grad;

: 57-48-7
D-Fructose

: 61-90-5
L-leucine

A: 529-96-4
pyridoxamine-5'-phosphate

B: 54-47-7
pyridoxal 5'-phosphate

C: 66-72-8
pyridoxal

D: 85-87-0
pyridoxamine

Conditions

Conditions	Yield
With air; ATCC 38399 h- leu1-32 In various solvent(s) at 30℃; for 36h; pH=4.5; Product distribution; Further Variations:; Reagents; reaction times; Microbiological reaction;

...Expand

: 2280-44-6
D-Glucose

: 61-90-5
L-leucine

A: 529-96-4
pyridoxamine-5'-phosphate

B: 54-47-7
pyridoxal 5'-phosphate

C: 66-72-8
pyridoxal

D: 85-87-0
pyridoxamine

Conditions

Conditions	Yield
With air; ATCC 38399 h- leu1-32 In various solvent(s) at 30℃; for 36h; pH=4.5; Product distribution; Further Variations:; Reagents; reaction times; Microbiological reaction;

...Expand

: 133-99-3, 490-37-9, 2152-98-9, 4482-75-1, 5965-66-2, 13299-27-9, 13360-52-6, 14641-93-1, 15548-43-3, 16462-44-5, 16984-36-4, 16984-38-6, 20869-27-6, 22688-72-8, 27452-49-9, 29276-55-9, 30608-12-9, 34481-13-5, 37169-60-1, 37169-64-5, 64234-01-1, 64234-02-2, 75281-88-8, 80446-85-1, 84413-57-0, 92344-56-4, 93221-87-5, 93301-77-0, 94799-29-8, 100427-98-3, 100428-00-0, 101312-82-7, 102046-24-2, 102046-25-3, 109432-00-0, 109432-02-2, 109432-04-4, 109432-08-8, 135268-49-4, 138231-26-2, 140461-59-2, 145414-22-8, 145414-26-2, 146339-75-5, 146339-76-6, 149116-55-2, 6363-53-7
Maltose

: 61-90-5
L-leucine

A: 529-96-4
pyridoxamine-5'-phosphate

B: 54-47-7
pyridoxal 5'-phosphate

C: 66-72-8
pyridoxal

D: 85-87-0
pyridoxamine

Conditions

Conditions	Yield
With air; ATCC 38399 h- leu1-32 In various solvent(s) at 30℃; for 36h; pH=4.5; Product distribution; Further Variations:; Reagents; reaction times; Microbiological reaction;

...Expand

: 3458-28-4
D-Mannose

: 61-90-5
L-leucine

A: 529-96-4
pyridoxamine-5'-phosphate

B: 54-47-7
pyridoxal 5'-phosphate

C: 66-72-8
pyridoxal

D: 85-87-0
pyridoxamine

Conditions

Conditions	Yield
With air; ATCC 38399 h- leu1-32 In various solvent(s) at 30℃; for 36h; pH=4.5; Product distribution; Further Variations:; Reagents; reaction times; Microbiological reaction;

...Expand

: 61-90-5
L-leucine

: 57-50-1
Sucrose

A: 529-96-4
pyridoxamine-5'-phosphate

B: 54-47-7
pyridoxal 5'-phosphate

C: 66-72-8
pyridoxal

D: 85-87-0
pyridoxamine

Conditions

Conditions	Yield
With air; ATCC 38399 h- leu1-32 In various solvent(s) at 30℃; for 36h; pH=4.5; Product distribution; Further Variations:; Reagents; reaction times; Microbiological reaction;

...Expand

: 98969-65-4
N-(3-hydroxy-2-methyl-5-phosphonooxymethyl-[4]pyridylmethylen)-alanine

A: 54-47-7
pyridoxal 5'-phosphate

B: 302-72-7
rac-Ala-OH

Conditions

Conditions	Yield
With potassium chloride; potassium acetate at 25℃; pH=5; Equilibrium constant; Further Variations:; pH-values;

: pyridoxal phosphate adduct of ethylamine

A: 54-47-7
pyridoxal 5'-phosphate

B: 75-04-7
ethylamine

Conditions

Conditions	Yield
With potassium chloride; potassium acetate at 25℃; pH=5; Equilibrium constant;

: 2-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(E)-ylidene]-amino}-2-methyl-propionic acid

A: 54-47-7
pyridoxal 5'-phosphate

B: 62-57-7
2-Aminoisobutyric acid

Conditions

Conditions	Yield
With potassium chloride; potassium acetate at 25℃; pH=5; Equilibrium constant; Further Variations:; pH-values;

: 2-{[1-(3-Hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(E)-ylidene]-amino}-2-methyl-malonic acid

A: 26767-88-4
α-amino-α-methylmalonic acid

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
With potassium chloride; potassium acetate at 25℃; pH=5; Equilibrium constant;

: (S)-3-(3,4-Dihydroxy-phenyl)-2-{[1-(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl)-meth-(E)-ylidene]-amino}-propionic acid

A: 59-92-7
levodopa

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
In water at 25℃; pH=7; Kinetics; Further Variations:; pH-values;

: 54-47-7
pyridoxal 5'-phosphate

: 130545-04-9, 139526-94-6
3-(aminooxy)-2-fluoropropanamine dihydrochloride

: 130545-69-6, 139527-03-0
2-fluoro-3-<<<<3-hydroxy-2-methyl-5-<(phosphonooxy)methyl>-4-pyridyl>methylidene>amino>oxy>propanamine hydrochloride

Conditions

Conditions	Yield
With sodium hydroxide for 1h; Ambient temperature;	99%

: 54-47-7
pyridoxal 5'-phosphate

: 626-43-7
3,5-Dichloroaniline

: C14H13Cl2N2O5P

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	98%

: 54-47-7
pyridoxal 5'-phosphate

: 87-62-7
2,6-dimethylaniline

: C16H19N2O5P

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	98%

: 54-47-7
pyridoxal 5'-phosphate

: 100-01-6
4-nitro-aniline

: C14H14N3O7P

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	96%

: 54-47-7
pyridoxal 5'-phosphate

: 3682-12-0
diethyltin(IV) oxide

: Sn(4+)*2CH3CH2(1-)*CH3C5HNH(O)(CHO)CH2OPO3(2-)*0.5H2O=[Sn(CH2CH3)2(CH3C5HN(OH)(CHO)CH2OPO3)]*0.5H2O

Conditions

Conditions	Yield
In ethanol; toluene Et2SnO added to soln. of pyridoxal 5-phosphate, refluxed for 10 h; distn., filtration, vac. drying, elem. anal.;	95%

: 54-47-7
pyridoxal 5'-phosphate

: 818-08-6
di(n-butyl)tin oxide

: Sn(4+)*2CH3(CH2)3(1-)*CH3C5HNH(O)(CHO)CH2OPO3(2-)=[Sn((CH2)3CH3)2(CH3C5HN(OH)(CHO)CH2OPO3)]

Conditions

Conditions	Yield
In ethanol; toluene Bu2SnO added to soln. of pyridoxal 5-phosphate, refluxed for 10 h; distn., filtration, vac. drying, elem. anal.;	95%

: 54-47-7
pyridoxal 5'-phosphate

: 2273-45-2
dimethyltin oxide

: Sn(4+)*2CH3(1-)*CH3C5HNH(O)(CHO)CH2OPO3(2-)=[Sn(CH3)2(CH3C5HN(OH)(CHO)CH2OPO3)]

Conditions

Conditions	Yield
In ethanol; toluene (CH3)2SnO added to soln. of pyridoxal 5-phosphate, refluxed for 10 h; distn., filtration, vac. drying, elem. anal.;	95%

: 54-47-7
pyridoxal 5'-phosphate

: 106-47-8
4-chloro-aniline

: 5371-85-7
Phosphoric acid mono-(4-{[(Z)-4-chloro-phenylimino]-methyl}-5-hydroxy-6-methyl-pyridin-3-ylmethyl) ester

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	93%

: 54-47-7
pyridoxal 5'-phosphate

: 104-94-9
4-methoxy-aniline

: C15H17N2O6P

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	92%

: 54-47-7
pyridoxal 5'-phosphate

: 67435-03-4, 130545-48-1, 139526-70-8, 139526-72-0, 139627-59-1
1-amino-3-(aminooxy)-2-propanol dihydrochloride

: 130545-70-9, 139527-01-8
C11H18N3O7P*2ClH*ClNa

Conditions

Conditions	Yield
With sodium hydroxide for 1h; Ambient temperature;	91%

: dimethyltin-diacetate

: 54-47-7
pyridoxal 5'-phosphate

: 7732-18-5
water

: Sn(4+)*2CH3(1-)*CH3C5HNH(O)(CHO)CH2OPO3(2-)*1.5H2O=[Sn(CH3)2(CH3C5HN(OH)(CHO)CH2OPO3)]*1.5H2O

Conditions

Conditions	Yield
With valine In methanol; water valine added to pyridoxal 5-phosphate in methanol-water (3:1), SnMe2(OAc)2 added and stirred for 12 h; filtration, washing (abs. methanol), vac. drying, elem. anal.;	89%

...Expand

: 54-47-7
pyridoxal 5'-phosphate

: 95-68-1
2,4-Xylidine

: C16H19N2O5P

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	89%

: 54-47-7
pyridoxal 5'-phosphate

: 91-59-8
naphthalen-2-ylamine

: (5-hydroxy-6-methyl-4-[(naphthalen-2-ylimino)methyl]pyridin-3-yl)methyl dihydrogen phosphate

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	88.5%

: 54-47-7
pyridoxal 5'-phosphate

: 73-22-3
L-Tryptophan

: 3-carboxy-1-<3-hydroxy-2-methyl-5-<(phosphonooxy)methyl>-4-pyridyl>-1,2,3,4-tetrahydro-β-carboline

Conditions

Conditions	Yield
With potassium phosphate buffer at 37℃;	88.2%
In water at 50 - 55℃; for 1h;

: 141-84-4
2-thioxo-4-thiazolidinone

: 54-47-7
pyridoxal 5'-phosphate

: (Z)-5'-O-phosphono-pyridoxylidenerhodanine

Conditions

Conditions	Yield
In ethanol for 0.333333h; Heating;	88%
In ethanol Heating;	85%

: 22184-99-2
3-(piperidine-1-sulfonyl)-phenylamine

: 54-47-7
pyridoxal 5'-phosphate

: 608523-46-2
6-[3-(1-Piperidinesulfonyl)phenylazo]-pyridoxal-5-phosphate

Conditions

Conditions	Yield
	88%

: 54-47-7
pyridoxal 5'-phosphate

: 51649-83-3
6'-amino-3,6-dihydroxyspiro-3'-one

: C28H21N2O10P

Conditions

Conditions	Yield
In ethanol for 4h; Reflux;	88%

: 54-47-7
pyridoxal 5'-phosphate

: 62-53-3
aniline

: 5371-86-8
(5-hydroxy-6-methyl-4-[(phenylimino)methyl]pyridin-3-yl)methyl dihydrogen phosphate

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	88%
In methanol at 24.84℃;	70%
In methanol for 48h;	44%

: 54-47-7
pyridoxal 5'-phosphate

: 657-27-2, 10098-89-2
L-Lysine hydrochloride

A: ε-(5-phosphopyridoxinyl)-L-lysine

B: α,ε-bis(5-phosphopyridoxinyl)-L-lysine

Conditions

Conditions	Yield
With potassium hydroxide; sodium tetrahydroborate In methanol at -15℃; for 1h;	A 87% B n/a

...Expand

: 372-19-0
meta-fluoroaniline

: 54-47-7
pyridoxal 5'-phosphate

: 6-(3-fluorophenylazo)pyridoxal-5'-phosphate

Conditions

Conditions	Yield
Stage #1: meta-fluoroaniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.0833333h; diazotization; Stage #2: pyridoxal 5'-phosphate With sodium hydroxide In water at 0℃; for 0.5h; pH=9; substitution;	87%

: 932013-08-6
rhodamine hydrazide

: 54-47-7
pyridoxal 5'-phosphate

: C34H36N5O7P

Conditions

Conditions	Yield
With acetic acid In methanol for 4h; Reflux;	87%

: 364-76-1
4-Fluoro-3-nitroaniline

: 54-47-7
pyridoxal 5'-phosphate

: 6-(4-fluoro-3-nitrophenylazo)pyridoxal-5'-phosphate

Conditions

Conditions	Yield
Stage #1: 4-Fluoro-3-nitroaniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.0833333h; diazotization; Stage #2: pyridoxal 5'-phosphate With sodium hydroxide In water at 0℃; for 0.5h; pH=9; substitution;	86%

: 824984-75-0
1-(2-aminoethyl)-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic acid tri(1,1-dimethylethyl ester)

: 54-47-7
pyridoxal 5'-phosphate

: 879999-83-4
1,4,7-tris(tert-butoxycarbonylmethyl)-10-{2-[(3-hydroxy-2-methyl-5-phosphonooxy-methyl-pyridin-4-ylmethylene)-amino]-ethyl}-1,4,7,10-tetraazacyclododecane

Conditions

Conditions	Yield
In methanol at 4 - 25℃; for 4h;	85%

: 54-47-7
pyridoxal 5'-phosphate

: 52130-17-3
3-amino-2-methylbenzoic acid

: 608523-41-7
6-(3-Carboxy-2-methylphenylazo)-pyridoxal-5-phosphate

Conditions

Conditions	Yield
	85%

: 54-47-7
pyridoxal 5'-phosphate

: 137-07-5
2-amino-benzenethiol

: C14H15N2O5PS

Conditions

Conditions	Yield
In methanol	85%

: 54-47-7
pyridoxal 5'-phosphate

: 2-(3,5-dimethyl-1H-pyrazol-4-yl)acetohydrazide

: {4-[(Z)-{[(3,5-dimethyl-1H-pyrazol-4-yl)acetyl]-hydrazono}methyl]-3-hydroxy-2-methylpyridin-5-yl}methyl phosphate

Conditions

Conditions	Yield
In water at 50℃; pH=7.44; Kinetics; pH-value;	85%

: 54-47-7
pyridoxal 5'-phosphate

: 40535-14-6
3-methyl-1H-pyrazole-5-carbohydrazide

: {3-hydroxy-2-methyl-4-[(Z)-{[(5-methyl-1H-pyrazol-3-yl)carbonyl]hydrazono}methyl]pyridin-5-yl}methyl phosphate

Conditions

Conditions	Yield
In water at 50℃; pH=7.44; Kinetics; pH-value;	85%

: 54-47-7
pyridoxal 5'-phosphate

: 26275-64-9
1H-pyrazole-3-carbohydrazide

: (3-hydroxy-2-methyl-4-{(Z)-[(1H-pyrazol-3-ylcarbonyl)hydrazono]methyl}pyridin-5-yl)methyl phosphate

Conditions

Conditions	Yield
In water at 50℃;	85%

: 768-05-8
pyrazine-2-carbohydrazide

: 54-47-7
pyridoxal 5'-phosphate

: (5-hydroxy-6-methyl-4-{(E)-[2-oxo-2-(pyrazin-2-yl)ethyl]hydrazinylidenemethyl}pyridin-3-yl)methylphosphate

Conditions

Conditions	Yield
In water at 20 - 80℃; for 1h;	84.6%

: 54-47-7
pyridoxal 5'-phosphate

: 24224-95-1
N-adamantan-1-yl-4-aminobenzenesulfonamide

: 6-[4-(N-(1-Adamantyl)sulfamoyl)phenylazo]-pyridoxal-5-phosphate Hydrochloride

Conditions

Conditions	Yield
	84%

Pyridoxal phosphate Chemical Properties

IUPAC Name: (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate
Synonyms of Piodel (CAS NO.54-47-7): 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate trihydrate ; 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)- ; Apolon B(sub 6) ; Apolon B6 ; Biosechs ; Codecarboxylase ; Coenzyme B6 ; EINECS 200-208-3 ; HI-Pyridoxin ; Hairoxal ; Hexermin P ; Hiadelon ; Himitan ; NSC 82388 ; PLP ; Pal-P ; Phosphopyridoxal ; Phosphopyridoxal coenzyme ; Phosphoridoxal coenzyme ; Pidopidon ; Piodel ; Pydoxal ; Pyridoxal 5-phosphate ; Pyridoxal P ; Pyridoxal monophosphate ; Pyridoxal phosphate ; Pyridoxal-5'-phosphate ; Pyridoxaldehyde phosphate ; Pyridoxyl phosphate ; Pyromijin ; Sechvitan ; UNII-F06SGE49M6 ; Vitahexin P ; Vitazechs ; Pyridoxal 5'-(dihydrogen phosphate)
CAS NO: 54-47-7
Classification Code: Drug / Therapeutic Agent ; Growth Substances ; Micronutrients ; Mutation data ; Vitamin B Complex ; Vitamins
Molecular Formula of Piodel (CAS NO.54-47-7): C₈H₁₀NO₆P
Molecular Weight: 247.1419
Molecular Structure:

Melting Point: 140-143 °C
Polar Surface Area: 93.76 Å²
Index of Refraction: 1.64
Molar Refractivity: 54.4 cm³
Molar Volume: 150.8 cm³
Surface Tension: 87.3 dyne/cm
Density of Piodel (CAS NO.54-47-7): 1.638 g/cm³
Flash Point: 296 °C
Enthalpy of Vaporization: 89.39 kJ/mol
Boiling Point: 565.7 °C at 760 mmHg
Vapour Pressure: 1.23E-13 mmHg at 25°C

Pyridoxal phosphate Uses

Piode (CAS NO.54-47-7) is an active form of vitamin b6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.

Pyridoxal phosphate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LD50	oral	> 3gm/kg (3000mg/kg)		British Patent Document. Vol. #1172800,
mammal (species unspecified)	LD50	subcutaneous	550mg/kg (550mg/kg)		British Patent Document. Vol. #1172800,
mouse	LD50	intramuscular	1150mg/kg (1150mg/kg)	BEHAVIORAL: ANTIPSYCHOTIC	Pharmaceutical Chemistry Journal Vol. 15, Pg. 303, 1981.
mouse	LD50	intravenous	530mg/kg (530mg/kg)		Drugs in Japan Vol. 6, Pg. 643, 1982.
mouse	LD50	oral	4640mg/kg (4640mg/kg)		Drugs in Japan Vol. 6, Pg. 643, 1982.
mouse	LD50	subcutaneous	870mg/kg (870mg/kg)		Drugs in Japan Vol. 6, Pg. 643, 1982.
rat	LD50	oral	5900mg/kg (5900mg/kg)		Drugs in Japan Vol. 6, Pg. 643, 1982.
rat	LD50	subcutaneous	850mg/kg (850mg/kg)		Drugs in Japan Vol. 6, Pg. 643, 1982.

Pyridoxal phosphate Consensus Reports

Reported in EPA TSCA Inventory.

Pyridoxal phosphate Safety Profile

Moderately toxic subcutaneous, intravenous, and intramuscular routes. Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x and PO_x.
Safety Statements: 22-24/25
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
F: 8-10-23

Product Name

Pyridoxal phosphate

Synthetic route

Pyridoxal phosphate Chemical Properties

Pyridoxal phosphate Uses

Pyridoxal phosphate Toxicity Data With Reference

Pyridoxal phosphate Consensus Reports

Pyridoxal phosphate Safety Profile

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