Sodium Citrate supplier | CasNO.68-04-2

Name
Sodium citrate
EINECS 200-675-3
CAS No. 68-04-2
Density 1.008 g/mL at 20 °C
Solubility Soluble in water.
Melting Point 300 °C
Formula C₆H₅Na₃O₇
Boiling Point 309.6 °C at 760 mmHg
Molecular Weight 258.071
Flash Point 155.2 °C
Transport Information
Appearance white to off-white crystalline powder
Safety 36-24/25
Risk Codes 22-40-48/20/22
Molecular Structure
Hazard Symbols Xi,C
Synonyms 1,2,3-Propanetricarboxylicacid, 2-hydroxy-, trisodium salt (9CI);Citric acid, trisodium salt (8CI);Sodiumcitrate (Na3C6H5O7) (7CI);331iii;Citnatin;Citra-lock;Citreme;Citrosodina;Citrosodine;Cystemme;Ional;Natrocitral;Sodium citrateanhydrous;Trisodium citrate;Unifine P 3;
PSA 140.62000
LogP -5.25260

Synthetic route

: 497-19-8
sodium carbonate

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
With lemon juice fermenting; clearing by CuSO4 and Na4(Fe(CN)6); filtration; adding soda up to wakly alkaline soln.; evapn.; crystn. of 80%; further 15% of product by pptn. of Ca(2+) by Na2CO3;;	80%

zinc citrate: zinc citrate

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
With sodium sulfide

: sodium phosphate

: calcium(II) citrate

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
In ammonia dissoln. of finely powd. Ca citrate (from lemon juice and Ca(OH)2) in H2O containing NH3; addn. of Na3PO4 with vigorous stirring at temp. <30°C; filtration; evapn.; crystn.;;

: disodium hydrogen citrate

: 1310-73-2
sodium hydroxide

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
In sodium hydroxide byproducts: H2O;
In sodium hydroxide byproducts: H2O;

: 77-92-9
citric acid

: 1310-73-2
sodium hydroxide

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
In sodium hydroxide neutralization;;
byproducts: H2O;
In sodium hydroxide byproducts: H2O;

: 5990-32-9
zinc citrate

: sodiumsulfide nonahydrate

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
In water
In water

: 497-19-8
sodium carbonate

: calcium(II) citrate

: 68-04-2
sodium citrate

: 7681-38-1
sodium hydrogen sulfate

: calcium(II) citrate

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
In ammonia dissoln. of finely powd. Ca citrate (from lemon juice and Ca(OH)2) in H2O containing NH3; addn. of NaHSO4 with vigorous stirring at temp. <30°C; filtration; evapn.; crystn.;;

: 7757-82-6
sodium sulfate

: calcium(II) citrate

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
In ammonia dissoln. of finely powd. Ca citrate (from lemon juice and Ca(OH)2) in H2O containing NH3; addn. of Na2SO4 with vigorous stirring at temp. <30°C; filtration; evapn.; crystn.;;

: 7440-70-2
calcium

: 68-04-2
sodium citrate

Conditions

Conditions	Yield
With urea In Na-Ac

: 68-04-2
sodium citrate

: micafungin sodium

Conditions

Conditions	Yield
In water	99.5%

: 68-04-2
sodium citrate

: 105-39-5
chloroacetic acid ethyl ester

: triethoxycarbonylmethyl citrate

Conditions

Conditions	Yield
With triethylamine In toluene at 110℃; under 397.54 Torr; for 17h; Heating / reflux;	91.5%

: 68-04-2
sodium citrate

: 100-51-6
benzyl alcohol

: 631-25-4
tribenzyl citrate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene Inert atmosphere; Reflux;	88%

: 100-39-0
benzyl bromide

: 68-04-2
sodium citrate

: 631-25-4
tribenzyl citrate

Conditions

Conditions	Yield
Stage #1: benzyl bromide; sodium citrate With tetrabutylammomium bromide In N,N-dimethyl-formamide at 80℃; for 8h; Stage #2: With triethylamine In N,N-dimethyl-formamide for 2h; Reagent/catalyst;	85%

: C31H49ClO4

: 68-04-2
sodium citrate

: C99H152O19

Conditions

Conditions	Yield
With triethylamine In cyclohexene at 80℃; for 5h;	82%

: 68-04-2
sodium citrate

: strontium(II) citrate

Conditions

Conditions	Yield
With strontium (III) chloride hexahydrate; water at 100℃; for 0.5h;	79%

: 68-04-2
sodium citrate

: 2338-05-8
ferric citrate

Conditions

Conditions	Yield
With iron(III) chloride hexahydrate In water at 80 - 90℃; for 1h;	78%

: 584-13-4
4-amino-1,2,4-triazole

: copper(II) nitrate hexahydrate

: 7732-18-5
water

: 68-04-2
sodium citrate

: [Cu2(4-amino-1,2,4-triazole)2(H2O)2(citrate)]n

Conditions

Conditions	Yield
With triethylamine In methanol at 100℃; for 96h; High pressure; Autoclave;	67%

...Expand

: 141061-25-8
4-Methoxybenzyl (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-methoxyiminoacetamido]-3-[(R)-tetrahydrofuran-2-yl]-ceph-3-em-4-carboxylate

: 68-04-2
sodium citrate

: 141195-78-0
sodium (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-methoxy-iminoacetamido]-3-[(R)-tetrahydrofuran-2-yl]ceph-3-em-4-carboxylate

Conditions

Conditions	Yield
aluminium chloride In dichloromethane; water; methoxybenzene	64%

: Gd(3+)*5Cu(2+)*11H2O*5C2H4N2O2(2-)*3NO3(1-)

: 68-04-2
sodium citrate

: [GdCu5(glycinehydroxamate)5(citrate)(H2O)4]·7H2O

Conditions

Conditions	Yield
With N,N-dimethyl-formamide In water Heating;	57%

: 584-13-4
4-amino-1,2,4-triazole

: 7732-18-5
water

: 6046-93-1
copper(II) acetate monohydrate

: 68-04-2
sodium citrate

: {[Cu4(4-amino-1,2,4-triazole)2(H2O)3(citrate)2]*3H2O}n

Conditions

Conditions	Yield
at 100℃; for 96h; High pressure; Autoclave;	50%

...Expand

: 584-13-4
4-amino-1,2,4-triazole

: copper(II) nitrate hexahydrate

: 7732-18-5
water

: 68-04-2
sodium citrate

: {[Cu2(4-amino-1,2,4-triazole)(H2O)3.25(citrate)]H2O}n

Conditions

Conditions	Yield
With lithium hydroxide In methanol at 100℃; for 96h; High pressure; Autoclave;	50%

...Expand

: 2,3-diamino-3-(ethylthio)acrylonitrile

: 68-04-2
sodium citrate

: 133940-72-4
3,6-diaminopyrazine-2,5-dicarbonitrile

Conditions

Conditions	Yield
With citric acid In 1,2-dimethoxyethane; water	48.7%

: iron(II) sulfate hexahydrate

: aqueous cadmium chloride

: 7732-18-5
water

: 68-04-2
sodium citrate

: [FeCd2(citrate)2(H2O)2]

Conditions

Conditions	Yield
With aq. HCl In ethanol; water High Pressure; tri-sodium citrate dissolved in EtOH/H2O with stirring; aq. solns. of FeSO46H2O and CdCl22.5H2O added into first soln. with stirring and pH value adjusted to 5 with aq. HCl; mixt. placed in Teflon-lined reactor andheated at 140°C for 5 d; elem. anal.;	35%

...Expand

: aqueous cadmium chloride

: 7732-18-5
water

: 68-04-2
sodium citrate

: [Cd3(citrato)2(H2O)2]n

Conditions

Conditions	Yield
With aq. HCl; NaSCN In ethanol; water High Pressure; tri-sodium citrate and NaSCN dissolved in H2O/Et and aq. CdCl2*2.5H2O added with stirring; pH value adjusted to 5 with aq. HCl; mixt. placed inTeflon-lined reactor and heated at 140°C for 5 d; elem. anal.;	20%

...Expand

: lead(II) nitrate

: 7732-18-5
water

: 68-04-2
sodium citrate

: Na(H2O)3[Pb5(citric acid-3H)3(citric acid-2H)(H2O)3]*9.5H2O

Conditions

Conditions	Yield
With HCl In water Pb(NO3)2 (0.172 mmol) and Na3(C6H6O7) (3.88 mmol) dissolved; pH adjustedto 4.5 with 2.0 M HCl; kept 2 wk; elem. anal.; TGA;	20%

...Expand

: Iron(III) nitrate nonahydrate

: potassium hexafluorozirconate

: 7732-18-5
water

: 68-04-2
sodium citrate

: [Fe6O2Zr2F6(citrate)4(H2O)10]·24H2O

Conditions

Conditions	Yield
for 240 - 336h;	15%

...Expand

: 68-04-2
sodium citrate

: 2956-91-4
1,1,3,3-tetraiodo-propan-2-one

Conditions

Conditions	Yield
With manganese (II)-salt; water; iodine Irradiation;

: 68-04-2
sodium citrate

A: 2956-91-4
1,1,3,3-tetraiodo-propan-2-one

B: hexaiodo-acetone

Conditions

Conditions	Yield
With cerium salt; water; iodine Irradiation;
With chromium salt; water; iodine Irradiation;
With iron salt; water; iodine Irradiation;

: 68-04-2
sodium citrate

: 97-67-6
(S)-Malic acid

Conditions

Conditions	Yield
With bacterium succinicum

: 68-04-2
sodium citrate

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With ammonium chloride mit Hilfe von Enzym-Systemen aus Saccharomyces cerevisiae oder Brevibacterium flavum;

: 68-04-2
sodium citrate

: 4023-65-8
trans-acotinic acid

Conditions

Conditions	Yield
With bacterium succinicum

: 68-04-2
sodium citrate

: 5785-44-4, 17499-10-4, 24846-38-6, 57528-02-6, 111461-69-9, 111461-70-2
citric acid ; calcium citrate

Conditions

Conditions	Yield
With water; calcium chloride at 60℃;

: 68-04-2
sodium citrate

: 5785-44-4, 17499-10-4, 24846-38-6, 57528-02-6, 111461-69-9, 111461-70-2
citric acid ; calcium citrate

Conditions

Conditions	Yield
With water; calcium chloride Faellen mit Alkohol;

: 68-04-2
sodium citrate

: 95347-86-7
citric acid ; strontium citrate

Conditions

Conditions	Yield
With water; strontium chloride at 25℃;

: 68-04-2
sodium citrate

: 95347-86-7
strontium citrate monohydrate

Conditions

Conditions	Yield
With water; strontium chloride bei Siedetemperatur;

: 68-04-2
sodium citrate

: 77402-64-3, 779989-66-1
calcium-citrate(3-) complex

Conditions

Conditions	Yield
With calcium chloride at 17.9℃; Thermodynamic data; pH above 8.0; ΔG0, ΔH0, ΔS0, ΔCP0;

: 98560-91-9
2,4,5-Trimethoxy-2-methyl-tetrahydro-furan

: 7647-01-0
hydrogenchloride

: 542-05-2
acetonedicarboxylic acid

: 593-51-1
methylamine hydrochloride

: 68-04-2
sodium citrate

: 6exo-methoxy-1-methyl-tropan-3-one

...Expand

Sodium Citrate Chemical Properties

Molecular Structure:

Molecular Formula: C₆H₅Na₃O₇
Molecular Weight: 258.069
IUPAC Name: Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
Synonyms of Sodium Citrate (CAS NO.68-04-2): 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt ; CCRIS 3293 ; Citnatin ; Citreme ; Citric acid, trisodium salt ; Citrosodina ; Citrosodine ; Citrosodna ; EINECS 200-675-3 ; FEMA No. 3026 ; HSDB 5201 ; Natrocitral ; Sodium citrate (Na3C6H5O7) ; Sodium citrate anhydrous ; Trisodium 2-hydroxy-1,2,3-propanetricarboxylate ; Trisodium citrate ; Trisodium citrate, anhydrous ; UNII-RS7A450LGA
CAS NO: 68-04-2
Classification Code: FOOD ADDITIVES ; Chemistry ; Cytochemistry Products ; Hematology and Histology ; ReagentsMore...Close... ; AlphabeticalMolecular Biology ; Biological Buffers ; BioUltra Buffers ; BioUltraBiological Buffers ; Buffer SolutionsBiochemicals and Reagents ; ChelatorsProtein Structural Analysis ; DNA&RNA Purification ; Molecular Biology Reagents ; Optimization ReagentsMolecular Biology ; X-Ray Crystallography ; Buffers A to Z ; AnticoagulantsBiological Buffers ; Buffers A to ZProteins and Derivatives ; Blood ; Buffer Convenience Packaging ; Buffer SolutionsBiological Buffers ; Coagulation Proteins and Reagents ; Immune Cell Signaling and Blood ; Plasma&Blood Proteins
Melting point: 300°C
H bond acceptors: 7
H bond donors: 4
Freely Rotating Bonds: 6
Polar Surface Area: 121.13 Å²
Flash Point: 155.2 °C
Enthalpy of Vaporization: 63.82 kJ/mol
Boiling Point: 309.6 °C at 760 mmHg
Vapour Pressure: 5.73E-05 mmHg at 25°C

Sodium Citrate Uses

Sodium Citrate (CAS NO.68-04-2) is used as a flavoring agent in certain varieties of club soda.
It is an ingredient in Benedict's reagent and is used by Canadian Blood Services as an anticoagulant during apheresis. When it comes in contact with water, it is a product of the chemical reaction Alka Seltzer produces.Sodium citrate is used in the relief of cystitis in women, its effect is to make the urine less acidic and therefore provide pain relief. Its is not recommended for children or men to use it.

Sodium Citrate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1364mg/kg (1364mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
mouse	LD50	intravenous	170mg/kg (170mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
rabbit	LD50	intravenous	449mg/kg (449mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
rat	LD50	intraperitoneal	1548mg/kg (1548mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.

Sodium Citrate Safety Profile

Risk Statements of Sodium Citrate (CAS NO.68-04-2): 20-40-48/22
R20: Harmful by inhalation.
R40: Limited evidence of a carcinogenic effect.
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed.
Safety Statements: 36-24/25
S36: Wear suitable protective clothing.
S24/25: Avoid contact with skin and eyes.
WGK Germany: 2
F: 34

Product Name

Sodium citrate

Synthetic route

Sodium Citrate Chemical Properties

Sodium Citrate Uses

Sodium Citrate Toxicity Data With Reference

Sodium Citrate Safety Profile

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