Trimethyl phosphate supplier

Name
Trimethyl phosphate
EINECS 208-144-8
CAS No. 512-56-1
Article Data152
CAS DataBase
Density 1.154 g/cm³
Solubility 500 G/L (25 ºC)
Melting Point -46 °C
Formula C₃H₉O₄P
Boiling Point 197.2 °C at 760 mmHg
Molecular Weight 140.076
Flash Point 83.7 °C
Transport Information UN 2810
Appearance clear liquid
Safety 53-36/37-45-36/37/39
Risk Codes 46-40-68-45-20/21/22
Molecular Structure
Hazard Symbols Xn,T
Synonyms Methylphosphate, (MeO)3PO (6CI);Trimethoxyphosphineoxide;Trimethyl orthophosphate;Trimethylphosphoric acid;
PSA 54.57000
LogP 1.03370

Synthetic route

: 67-56-1
methanol

: 512-56-1
trimethyl phosphite

Conditions

Conditions	Yield
With sodium hypophosphite; copper dichloride at 24.9℃; for 173h;	100%
With phosphorous; phosphoric acid tributyl ester; oxygen; copper dichloride In benzene at 30℃;	98.2%
With trichlorophosphate In acetone at 10 - 30℃; under 10 Torr; for 4h;	97.5%

: 121-45-9
phosphorous acid trimethyl ester

: 512-56-1
trimethyl phosphite

Conditions

Conditions	Yield
With sulfur trioxide In dichloromethane at -95℃;	100%
With dihydrogen peroxide In pyridine at -20℃; adding different FeIII compounds; determination of half-lives of reactions;
With naphthalene-1,4-dicarbonitrile; water In water; acetonitrile Irradiation;

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 77-78-1
dimethyl sulfate

Conditions

Conditions	Yield
With sulfur trioxide In dichloromethane at -50℃;	A 7% B 93%

: 122203-30-9
dimethyl (Z)-α-methoxyiminobenzylphosphonate

A: 512-56-1
trimethyl phosphite

B: 100-47-0
benzonitrile

Conditions

Conditions	Yield
at 140℃; for 0.5h; Product distribution; reflux in 1,2,4-trimethylbenzene, 72 h;	A 85% B 92%

: 67-56-1
methanol

: 7357-14-4
p-methoxyphenyl dimethyl phosphate

A: 512-56-1
trimethyl phosphite

B: 150-76-5
4-methoxy-phenol

Conditions

Conditions	Yield
With cesium fluoride at 65℃; for 22h;	A 79% B 88%

...Expand

: 67-56-1
methanol

: 74532-26-6, 74532-27-7
1-decenyl dimethyl phosphate

A: 512-56-1
trimethyl phosphite

B: 112-31-2
caprinaldehyde

Conditions

Conditions	Yield
With cesium fluoride at 65℃; for 22h;	A 67% B 88%

...Expand

: 7357-14-4
p-methoxyphenyl dimethyl phosphate

A: 512-56-1
trimethyl phosphite

B: 150-76-5
4-methoxy-phenol

Conditions

Conditions	Yield
With methanol; cesium fluoride at 65℃; for 22h;	A 79% B 88%

: 74532-26-6, 74532-27-7
1-decenyl dimethyl phosphate

A: 512-56-1
trimethyl phosphite

B: 112-31-2
caprinaldehyde

Conditions

Conditions	Yield
With methanol; cesium fluoride at 65℃; for 22h;	A 67% B 88%

: 67-56-1
methanol

A: 512-56-1
trimethyl phosphite

B: 812-00-0
methylphosphate

C: 813-78-5
dimethylphosphoric acid

Conditions

Conditions	Yield
With phosphorus; tetraethylammonium iodide In water; acetonitrile electrolysis;	A 82% B n/a C n/a

...Expand

: 67-56-1
methanol

: 10113-28-7
dimethyl phenyl phosphate

A: 512-56-1
trimethyl phosphite

B: 108-95-2
phenol

Conditions

Conditions	Yield
With cesium fluoride at 65℃; for 4h;	A 80% B 65%

...Expand

: 10113-28-7
dimethyl phenyl phosphate

A: 512-56-1
trimethyl phosphite

B: 108-95-2
phenol

Conditions

Conditions	Yield
With methanol; cesium fluoride at 65℃; for 4h;	A 80% B 65%

: 67-56-1
methanol

: 950-35-6
methyl paraoxon

A: 512-56-1
trimethyl phosphite

B: 100-02-7
4-nitro-phenol

Conditions

Conditions	Yield
With cesium fluoride at 65℃; for 0.5h;	A 63% B 76%
With La-(catecholate)-functionalized porous organic polymer at 60℃; for 12h; Kinetics; Reagent/catalyst;
Stage #1: methanol With UiO-66-H for 0.5h; Stage #2: methyl paraoxon at 59.84℃;

...Expand

: 950-35-6
methyl paraoxon

A: 512-56-1
trimethyl phosphite

B: 100-02-7
4-nitro-phenol

Conditions

Conditions	Yield
With methanol; cesium fluoride at 65℃; for 0.5h;	A 63% B 76%

: 31142-23-1
trimethyl phosphonoformate

A: 512-56-1
trimethyl phosphite

B: 756-79-6
dimethyl methane phosphonate

Conditions

Conditions	Yield
at 295℃; for 6h;	A 18% B 75%

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 96-36-6, 868-85-9
methyl phosphite

Conditions

Conditions	Yield
With Oxone In tetrahydrofuran; methanol Ambient temperature;	A 72% B n/a

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 152-18-1
O,O,O-trimethylthiophosphate

C: 756-79-6
dimethyl methane phosphonate

Conditions

Conditions	Yield
With sulfur trioxide In dichloromethane at -95℃;	A 25% B 4% C 71%

...Expand

: 67-56-1
methanol

A: 512-56-1
trimethyl phosphite

B: 868-85-9
Dimethyl phosphite

Conditions

Conditions	Yield
With phosphorous; 10H-phenothiazine; N,N,N,N-tetraethylammonium tetrafluoroborate In N,N-dimethyl-formamide at 53℃; electrolysis;	A 9% B 71%

: 67-56-1
methanol

A: 512-56-1
trimethyl phosphite

B: 868-85-9
Dimethyl phosphite

C: 756-79-6
dimethyl methane phosphonate

Conditions

Conditions	Yield
With phosphorous; tetraethylammonium iodide In acetonitrile at 18℃; electrolysis;	A 70% B 11% C 3%
With phosphorous; tetraethylammonium iodide In acetonitrile at 18℃; Mechanism; Product distribution; electrolysis; var. nucleophiles; var. temperatures;	A 70% B 11% C 3%
With phosphorous In acetonitrile at 18℃; Electrolysis;	A 70% B 11% C 3%

...Expand

: 152-18-1
O,O,O-trimethylthiophosphate

: 512-56-1
trimethyl phosphite

Conditions

Conditions	Yield
With Oxone In tetrahydrofuran; methanol Ambient temperature;	70%
With 3-chloro-benzenecarboperoxoic acid at -25℃; Yield given;
With ozone at 50℃; for 2.5h; neat (no solvent);

: 67-56-1
methanol

A: 512-56-1
trimethyl phosphite

B: 690-49-3
tetramethyl pyrophosphate

Conditions

Conditions	Yield
With tetraethylammonium iodide; water In acetonitrile at 48℃; electrosynthesis;	A 65% B 5%

: 591-87-7
Allyl acetate

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 757-54-0
allylphosphonic acid dimethyl ester

Conditions

Conditions	Yield
With palladium(II) acetylacetonate In 1,4-dioxane at 145 - 160℃; for 15h;	A 17% B 64%

...Expand

: (4R*,5S*)-2,2,2-Trimethoxy-4,5-diphenyl-1,3,2λ5-oxazaphospholidin

A: 512-56-1
trimethyl phosphite

: 25125-72-8
trans-2,2-Diphenylaziridine

Conditions

Conditions	Yield
With methanol In dichloromethane at 40℃; for 0.5h;	A n/a B 62%

: 67-56-1
methanol

: 74783-15-6
C10H19O8P

A: 512-56-1
trimethyl phosphite

B: 4148-97-4
dimethyl 2-methoxybutanedioate

C: 115-10-6
Dimethyl ether

D: 2-(Dimethoxy-phosphoryl)-3-methoxy-succinic acid dimethyl ester

Conditions

Conditions	Yield
at 150℃; for 20h; Product distribution; reaction under var. conditions;	A 60% B n/a C n/a D 40%
at 150℃; for 2h;

...Expand

: 6-Hydroxy-5-(trimethoxyphosphoranylidenamino)-5,6-dihydro-β-ionon

A: 512-56-1
trimethyl phosphite

B: 5,6-epimino-5,6-dihydro-β-ionone

C: 5-Dimethoxyphosphorylamino-6-hydroxy-5,6-dihydro-β-ionon

Conditions

Conditions	Yield
With water In tetrahydrofuran	A n/a B 10% C 57%

...Expand

: 699-18-3, 32782-45-9
2-(2-nitrovinyl)furan

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 2697-42-9
phosphoramidic acid dimethyl ester

C: tetramethyl <(2-furyl)ethylene>bisphosphonate

Conditions

Conditions	Yield
In acetic acid at 40℃; for 24h;	A 16 g B 5 g C 55%
In acetic acid at 40℃; for 24h; Product distribution; Mechanism;	A 16 g B 5 g C 10 g
In acetic acid at 40℃; for 24h;	A 16 g B 5 g C 10 g

...Expand

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 152-18-1
O,O,O-trimethylthiophosphate

C: 77-78-1
dimethyl sulfate

D: 756-79-6
dimethyl methane phosphonate

Conditions

Conditions	Yield
With sulfur trioxide In dichloromethane at -78℃; Product distribution; other trialkyl phosphite,trialkyl phosphine, trialkyl arsines, trialkoxyarsines, var. molar ratio and temperatures;	A 22% B 4% C 55% D 19%
With sulfur trioxide In dichloromethane at -78℃;	A 48% B 16% C 3% D 9%

...Expand

: 67-56-1
methanol

A: 512-56-1
trimethyl phosphite

B: 756-79-6
dimethyl methane phosphonate

Conditions

Conditions	Yield
With phosphorous; tetraethylammonium iodide In acetonitrile at 50℃; electrolysis;	A 51% B 28%
With phosphorous In acetonitrile at 50℃; Electrolysis;	A 51% B 28%

: 67-56-1
methanol

: 920-66-1
1,1,1,3',3',3'-hexafluoro-propanol

A: 512-56-1
trimethyl phosphite

B: 19784-21-5
O,O-dimethyl O-(1,1,1,3,3,3-hexafluoropropan-2-yl) phosphate

C: Bis(hexafluoroisopropyl) methyl phosphate

D: C13H7F24O5P

Conditions

Conditions	Yield
Stage #1: 1,1,1,3',3',3'-hexafluoro-propanol With phosphorus pentachloride for 2h; Heating; Stage #2: methanol	A 2% B 6% C 12% D 50%

...Expand

: 121-45-9
phosphorous acid trimethyl ester

A: 512-56-1
trimethyl phosphite

B: 7211-39-4
dimethyl phosphine oxide

Conditions

Conditions	Yield
With Bromotrichloromethane In neat (no solvent) at 25℃; for 0.5h;	A 4% B 50%

: 152-18-1
O,O,O-trimethylthiophosphate

: 19602-00-7
3-methylpyridazine-2-oxide

A: 1632-76-4
3-methylpyridazine

B: 512-56-1
trimethyl phosphite

Conditions

Conditions	Yield
In dichloromethane for 5h; Product distribution; Irradiation; different thiophosphoryl compounds, its concentrations and reaction times;	A 43% B 27%

...Expand

: 512-56-1
trimethyl phosphite

: 119750-30-0
3-Hydroxy-7,8-dimethyl-1-oxo-2-phenyl-1,5-dihydro-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile

: 119750-43-5
3-Methoxy-5,7,8-trimethyl-1-oxo-2-phenyl-1,5-dihydro-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile

Conditions

Conditions	Yield
With potassium carbonate for 1.5h; Heating;	100%

: 616-47-7
1-methyl-1H-imidazole

: 512-56-1
trimethyl phosphite

: 1-methyl-3-methylimidazol-3-ium dimethyl phosphate

Conditions

Conditions	Yield
at 20 - 140℃; for 4h;	100%
In acetonitrile at 80℃; for 24h; Inert atmosphere;	99%
at 100℃; for 24h;	95%

: 512-56-1
trimethyl phosphite

: 79917-90-1
1-butyl-3-methylimidazolium chloride

: 1-butyl-3-methyl-1H-imidazol-3-ium dimethyl phosphate

Conditions

Conditions	Yield
at 100℃; for 2h;	100%
at 60℃; for 5h;	100%

: 512-56-1
trimethyl phosphite

: 7368-65-2
tetraethyl-phosphonium chloride

: tetraethylphosphonium dimethylphosphate

Conditions

Conditions	Yield
at 100℃; for 3h;	100%

: 7098-07-9
N-Ethylimidazole

: 512-56-1
trimethyl phosphite

: 945611-27-8
1-ethyl-3-methyl-1H-imidazol-3-ium dimethyl phosphate

Conditions

Conditions	Yield
In neat liquid at 80℃; for 18h; Reflux; Inert atmosphere;	100%
at 80℃; for 24h; Inert atmosphere;	99%
In tetrahydrofuran Reflux;
at 150℃; for 15h; Inert atmosphere;
at 149.99℃; for 10h;

: 512-56-1
trimethyl phosphite

: 3-(2-hydroxyethyl)-1-methyl-1H-imidazol-3-ium chloride

: 1-(2-hydroxyethyl)-3-methylimidazolium dimethyl phosphate

Conditions

Conditions	Yield
at 50℃; for 0.25h; Microwave irradiation;	100%
With calcium chloride In toluene at 110℃; for 2h;	99%

: 512-56-1
trimethyl phosphite

: 93-98-1
N-phenyl benzoyl amide

: 1934-92-5
N-methyl-N-phenyl-benzamide

Conditions

Conditions	Yield
With cyclopentyl methyl ether; sodium hydroxide at 115℃; for 24h; Reagent/catalyst; Inert atmosphere;	100%
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h; Reagent/catalyst; Solvent; Temperature; regioselective reaction;	99%

: 512-56-1
trimethyl phosphite

: 1,6-bis(3-methylimidazolium-1-yl)hexane dichloride

: 1,6-bis(3-methylimidazolium-1-yl)hexane bis(dimethyl phosphate)

Conditions

Conditions	Yield
With calcium chloride In toluene at 120℃; for 4h;	99%

: 512-56-1
trimethyl phosphite

: 1,4-bis(1-butylimidazolium-3-yl)butane dichloride

: 1,4-bis(3-butylimidazolium-1-yl)butane bis(dimethyl phosphate)

Conditions

Conditions	Yield
With calcium chloride In toluene at 100℃; for 8h;	99%

: 512-56-1
trimethyl phosphite

: 1,6-bis[3-(2-hydroxyethyl)imidazolium-1-yl]hexane dichloride

: 1,6-bis[3-(2-hydroxyethyl)imidazolium-1-yl]hexane bis(dimethyl phosphate)

Conditions

Conditions	Yield
With calcium chloride In toluene at 120℃; for 2h;	99%

: 512-56-1
trimethyl phosphite

: 1-methyl-3-(2-methoxyethyl)-1H-imidazol-3-ium chloride

: 1-(2-methoxyethyl)-3-methylimidazolium dimethyl phosphate

Conditions

Conditions	Yield
With calcium chloride In toluene at 110℃; for 4h;	99%

: 512-56-1
trimethyl phosphite

: 3-butyl-1,2-dimethylimidazolium chloride

: 945611-42-7
1-butyl-2,3-dimethylimidazolium dimethyl phosphate

Conditions

Conditions	Yield
With calcium chloride In toluene at 100℃; for 2h;	99%

: 512-56-1
trimethyl phosphite

: 67-48-1
choline chloride

: 118978-98-6
(2-hydroxyethyl)trimethylammonium dimethyl phosphate

Conditions

Conditions	Yield
With calcium chloride In toluene at 120℃; for 2h;	99%
In methanol at 80℃; for 12h;

: 512-56-1
trimethyl phosphite

: 1-butyl-1-methylpyrrolidinium chloride

: 1323125-78-5
1-butyl-1-methylpyrrolidinium dimethyl phosphate

Conditions

Conditions	Yield
With calcium chloride In toluene at 110℃; for 2h;	99%

: 512-56-1
trimethyl phosphite

: 459409-74-6
4,4,5,5-tetramethyl-2-(5-phenylthiophen-2-yl)-1,3,2-dioxaborolane

: 5069-26-1
2-methyl-5-phenylthiophene

Conditions

Conditions	Yield
With copper(l) iodide; lithium iodide; lithium tert-butoxide at 50℃; for 16h; Inert atmosphere;	99%

: 512-56-1
trimethyl phosphite

: 3389-53-5
phenylacetylpyrrolidine

: 74931-56-9
2-phenyl-1-(pyrrolidin-1-yl)propan-1-one

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h;	99%

: 512-56-1
trimethyl phosphite

: 17123-83-0
N-(phenylacetyl)morpholine

: 155222-99-4
1-(4-morpholinyl)-2-phenyl-1-propanone

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h;	99%

: 512-56-1
trimethyl phosphite

: 18925-69-4
N,N-dimethyl-2-phenylacetamide

: 81616-82-2, 81616-83-3, 41836-85-5
N,N-dimethyl-2-phenylpropionamide

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h;	99%

: 512-56-1
trimethyl phosphite

: 588-46-5
N-(phenylmethyl)acetamide

: 29823-47-0
N-benzyl-N-methylacetamide

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h;	99%

: 616-45-5
2-pyrrolidinon

: 512-56-1
trimethyl phosphite

: 872-50-4
1-methyl-pyrrolidin-2-one

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h;	99%

: 512-56-1
trimethyl phosphite

: 151647-54-0
3-phenyl-1-pyrrolidin-1-yl-propane-1-one

: 2-methyl-3-phenyl-1-(pyrrolidin-1-yl)propan-1-one

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 75℃; for 24h;	99%

: 512-56-1
trimethyl phosphite

: 5830-31-9
N,N-dimethyl-3-phenylpropanamide

: 20929-40-2
2-methyl-N,N-dimethyl-3-phenylpropanamide

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 75℃; for 24h;	99%

: 512-56-1
trimethyl phosphite

: 153392-54-2
tetrahydro-2'-methyl-3'-phenylspiro(cyclopentane-1,5'-isoxazole)

: 3,3-dimethyl-4-phenyl-6-spirocyclopentyltetrahydro-1,3-oxazinium dimethyl phosphate

Conditions

Conditions	Yield
at 160℃; for 0.5h;	98%

: 512-56-1
trimethyl phosphite

: (3R*,5S*)-2,5-dimethyl-3-phenyl-5-propylisoxazolidine

: (4R*,6S*)-3,3,6-trimethyl-4-phenyl-6-propyltetrahydro-1,3-oxazinium dimethyl phosphate

Conditions

Conditions	Yield
at 160℃; for 0.5h;	98%

: 512-56-1
trimethyl phosphite

: 4316-42-1
1-Butylimidazole

: 1-butyl-3-methyl-1H-imidazol-3-ium dimethyl phosphate

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 24h; Inert atmosphere;	98%
In ethyl acetate at 80℃; Inert atmosphere;	76.5%
In tetrahydrofuran Reflux;
at 110℃; for 24h; Inert atmosphere;

: 512-56-1
trimethyl phosphite

: 109-64-8
1,3-dibromo-propane

: 177342-84-6
(3-bromopropyl)phosphonic acid dimethyl ester

Conditions

Conditions	Yield
at 150℃; for 0.5h;	98%

: 512-56-1
trimethyl phosphite

: 21252-69-7
N-octylimidazole

: 945611-33-6
1-octyl-3-methylimidazolium dimethyl phosphate

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 24h; Inert atmosphere;	98%

: methyl 2-(3-methyl-1H-imidazolium-1-yl)acetate chloride

: 512-56-1
trimethyl phosphite

: 1-(2-methoxy-2-oxoethyl)-3-methylimidazolium dimethyl phosphate

Conditions

Conditions	Yield
With calcium chloride In acetonitrile for 2h; Reflux;	98%

Trimethyl phosphate Consensus Reports

Trimethyl phosphate Specification

The IUPAC name of this chemical is Trimethyl phosphate. With the CAS registry number 512-56-1 and EINECS registry number 208-144-8, it is also named as Phosphoric acid,trimethyl ester. In addition, the molecular formula is C₃H₉O₄P and the molecular weight is 140.07. It is a kind of clear liquid and belongs to the classes of Organics; Functional Materials; Phosphates (Plasticizer); Plasticizer; Organic Building Blocks; Organic Phosphates/Phosphites; Phosphorus Compounds.

Physical properties about this chemical are: (1)ACD/LogP: -0.52; (2)ACD/LogD (pH 5.5): -0.52; (3)ACD/LogD (pH 7.4): -0.52; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 12.46; (7)ACD/KOC (pH 7.4): 12.46; (8)#H bond acceptors: 4; (9)#Freely Rotating Bonds: 3; (10)Polar Surface Area: 54.57 Å²; (11)Index of Refraction: 1.379; (12)Molar Refractivity: 28.05 cm³; (13)Molar Volume: 121.2 cm³; (14)Polarizability: 11.12 ×10^-24cm³; (15)Surface Tension: 29.4 dyne/cm; (16)Density: 1.154 g/cm³; (17)Flash Point: 83.7 °C; (18)Enthalpy of Vaporization: 41.57 kJ/mol; (19)Boiling Point: 197.2 °C at 760 mmHg; (20)Vapour Pressure: 0.539 mmHg at 25°C.

Preparation of Trimethyl phosphate: it can be prepared by methanol and trichlorooxyphosphorus in the presence of potassium carbonate. Add methanol and potassium carbonate into reactor at reaction temperature of 5 °C. Then add trichlorooxyphosphorus into the mixture in 2 hours with stirring. The temperature should be controlled below 30 °C. Then add dimethyl sulfate and reflux for 3 hours. At last, you can go through the operation of cooling, filtering by carbon tetrachloride, vacuum distillation and drying to get the products.

Trimethyl phosphate can be prepared by methanol and trichlorooxyphosphorus in the presence of potassium carbonate

Uses of Trimethyl phosphate: this chemical is a mild methylating agent, useful for preparing dimethylation of anilines and related heterocyclic compounds.And it is mianly used as solvent and extractant for medicine and pesticide. Also it can be used as a color inhibitor for fibers, flame retardants and plasticizer. In addition, it can react with pyridine to get 1-methyl-pyridinium; dimethyl phosphate. The reaction time is 5 hours by heating. The yield is about 92%.

Trimethyl phosphate can react with pyridine to get 1-methyl-pyridinium; dimethyl phosphate

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. And it may cause heritable genetic damage and cancer. In addition, it has risk of irreversible effects Possibly. There is limited evidence of a carcinogenic effect. Avoid exposure - obtain special instruction before use. During using it, wear suitable protective clothing, gloves and eye/face protection. And in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.).

You can still convert the following datas into molecular structure:
(1)SMILES: O=P(OC)(OC)OC
(2)InChI: InChI=1/C3H9O4P/c1-5-8(4,6-2)7-3/h1-3H3
(3)InChIKey: WVLBCYQITXONBZ-UHFFFAOYAV

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	1676mg/kg (1676mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1129, 1986.
mouse	LD50	intraperitoneal	2250mg/kg (2250mg/kg)		Therapie. Vol. 15, Pg. 237, 1960.
mouse	LD50	oral	1470mg/kg (1470mg/kg)		Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
mouse	LD50	unreported	540mg/kg (540mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Gigiena Naselennykh Mest. Hygiene in Populated Places. Vol. 17, Pg. 37, 1978.
quail	LD50	oral	750mg/kg (750mg/kg)		Journal of Reproduction and Fertility. Vol. 48, Pg. 371, 1976.
rabbit	LD50	oral	1275mg/kg (1275mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 338, 1946.
rabbit	LD50	skin	2830uL/kg (2.83mL/kg)		American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat	LD50	oral	840mg/kg (840mg/kg)		Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rat	LD50	unreported	500mg/kg (500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Gigiena Naselennykh Mest. Hygiene in Populated Places. Vol. 17, Pg. 37, 1978.
rat	LDLo	intraperitoneal	800mg/kg (800mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC GASTROINTESTINAL: OTHER CHANGES	Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959.
rat	LDLo	intravenous	2400mg/kg (2400mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Nature. Vol. 179, Pg. 154, 1957.

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