We report outcomes from 52 patients with chronic osteomyelitis from implant infection treated with a single stage protocol including debridement augmented with application of CERAMENT™/G biocomposite after resection of Cierny-Mader (C-M) stage III and IV chronic osteomyelitis. Mean age was 53 ye...
Duramycin is a 19-amino-acid tetracyclic lantibiotic closely related to cinnamycin (Ro09-0198), which is known to bind phosphatidylethanolamine (PE). The lipid specificity of duramycin was not established. The present study indicates that both duramycin and cinnamycin exclusively bind to ethanol...
In this mini-review, we summarize current knowledge about the lipid-binding characteristics of two types of toxins used to visualize the membrane distribution of phosphoethanolamine-containing lipid species: the glycerophospholipid, phosphatidylethanolamine (PE) and the sphingolipid, ceramide ph...
In this study, the interaction of amphotericin B with human and bovine serum albumins has been investigated by fluorescence spectroscopy. Due to the limitations of several analytical methods by the known aggregation of amphotericin B molecules in aqueous solutions, fluorescence polarization tech...
Mucormycosis is a rare but potentially mortal opportunistic infection caused by Mucorales. We present a case of rhinoorbital mucormycosis in an 11-year old male with neuroblastoma successfully treated with aggressive surgical debridement and antifungal combination of liposomal amphotericin B and...
This report describes the first case of visceral leishmaniasis (VL) resistant to pentavalent antimonials and also the first use of combinational therapy in Iran. The patient was a two-year old boy, from a non-endemic area for leishmaniasis in northern Iran, presenting with pentavalent antimonial...
ObjectivesThis study aimed to describe the preparation and in vitro evaluation of a surface-modified nanostructured lipid carrier (NLC) using chitosan and dextran for co-delivery of buparvaquone (BPQ) and polymyxin B (PB) against leishmaniasis.
In this work, interactions of carboxylated core shell magnetic nanoparticles with polymyxin B sulfate were studied by connecting capillary electrophoresis with inductively coupled plasma mass spectrometry. The interaction was probed by affinity mode of capillary electrophoresis with 25 mM phosph...
This work presents the outcomes of a comparative study of molecular interactions of polymyxin B (PMB) and F12 and F13 formulations in the mole ratios of 1:2 and 1:3 of PMB:sodium deoxycholate sulfate (SDCS), respectively, and a commercial PMB formulation (CPMB) with lipopolysaccharides (LPS). Se...
Bacterial infection is a major problem world-wide, especially in wound treatment where it can severely prolong the healing process. In this study, a double drug co-delivery elastic antibacterial nanocomposite was developed by combining ciprofloxacin (CPX) and polymyxin B sulfate-loaded halloysit...
In this study, the power output of a microbial fuel cell (MFC) inoculated with R. pyridinivorans sp. strain HR-1 has been successfully improved by the addition of the antibiotic polymyxin B sulfate. Pores are observed clearly in SEM images while CV measurement shows an enhancement of electrochem...
We present the first study on the analytical methods of phenyltin compounds (PTs) in polychlorinated biphenyl (PCB)-based transformer oil samples. Tetraphenyltin (TePhT) has been used as stabilizer for some kinds of PCBs-based transformer oil formulations. Monophenyltin (MPhT), diphenyltin (DPhT...
The aim of this work is to estimate background concentrations of organometallic compounds, such as tributyltin (TBT), dibutyltin (DBT), monobutyltin (MBT), triphenyltin (TPhT), diphenyltin (DPhT), monophenyltin (MPhT), methylmercury (MeHg), inorganic mercury (iHg) and diethyllead (Et2Pb) in the ...
The degradation of organotin compounds (OTC) in agricultural and forest soils is studied in sandy soil samples. Individual experiments involving the three butyl- and the three phenyltins were carried out during 90 d in controlled conditions (darkness, 28 °C, aerobic conditions, 13% moisture) an...
Although the fate of organotins has been widely studied in the marine environment, fewer studies have considered their impact in terrestrial systems. The degradation and toxicity of triphenyltin in autoclaved, autoclaved-reinoculated and non-sterilised soil was studied in a 231 day incubation ex...
The electrochemical behaviour of phenyltin trichloride has been studied using various electrochemical techniques including polarography, coulometry and cyclic voltammetry. Phenyltin trichloride has been found to show a single major polarographic wave corresponding to a three-electron reduction p...
Photocatalytic oxidation (PCO) technology has a great potential for indoor air purification. However, the presence of humidity and different concentrations of a variety of pollutants are critical parameters that must be addressed for indoor air cleaning applications. In this work, the photodegra...
Toluene, a widely used and commonly abused organic solvent, causes a variety of behavioral disturbances in both humans and animals. In this study, the effects of toluene on locomotor activity, motor coordination, and passive avoidance learning, along with the possible mechanism underlying these ...
The adsorption of the alkali-metal cation (M = Li+, Na+, K+, Rb+, and Cs+) and the reaction mechanism of the side-chain alkylation of toluene with formaldehyde over MY basic zeolite (M = Rb+ and Cs+) were investigated using density functional theory calculations. During co-adsorption, the zeolit...
The properties of sulfolane + benzene-toluene-xylenes (BTXs) liquid mixtures were analyzed using computational chemistry methods, molecular dynamics simulations and quantum chemistry calculations, in order to infer the main features of intermolecular forces and structural characteristics that ma...
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