The oxidations of oleoyl residue of its esters with ethylene glycol, glycerol and erythritol were measured at 80 °C and 0% relative humidity. The oxidation rate of each substrate could be expressed by the rate expression of the autocatalytic type. The susceptibility of oleoyl residue to oxidati...

Oleoyl-estrone (OE) is a powerful anti-obesity compound that decreases food intake, decreases insulin resistance and circulating cholesterol. OE stimulates a severe loss of body fat by decreasing adipose tissue lipid synthesis and maintaining lipolysis. Therefore, the body economy loses lipid en...

A nanostructure lipid carrier (NLC) composed of solid, and liquid lipid as a core has been developed as a delivery system for hydrophobic drug molecules. The aim of this research was to fabricate an oleoyl-quaternized-chitosan (CS)-coated NLC, where the mucoadhesive property of nanoparticles is ...

Oleic acid-based amphiphilic surfactants were synthesized using three amino acids namely isoleucine (Ile), phenylalanine (Phe), and proline (Pro) containing aliphatic, aromatic and alicyclic moiety as polar head group. N-Oleoyl amino acids were prepared using Schotten-Baumann reaction by reactin...

Oleoyl-carboxymethyl chitosan (OCMCS) was synthesized by reacting carboxymethyl chitosan (CMCS) with oleoyl chloride. The FT-IR spectra suggested the formation of an amide linkage between amino groups of CMCS and oleoyl chloride. The solubility property of OCMCS was similar with CMCS. The CS was...

Spills due to the floating oil on the surface of sea water shows a significant alteration in the natural phenomenon of the marine ecosystem. Hence, amphiphilic sodium salt of oleoyl carboxymethyl chitosan (NaO-CMCS) was synthesized, characterized and studied as a sustainable adsorbent for the re...

Cigarette smokers with brain damage involving the insular cortex display cessation of tobacco smoking, suggesting that this region may contribute to nicotine addiction. In the present study, we speculated that molecules in the insular cortex that are sensitive to experimental traumatic brain inj...

Selective separation of Ga3+ was studied through a microporous polypropylene membrane impregnated with N-octadecanoyl-N-phenylhydroxylamine (ODPHA). The present membrane selectively concentrated Ga3+ from a Ga3+Al3+ mixture against the concentration gradient, with a counter flow of H+ as a drivi...

The crystal structure of 1,8-bis(dimethylamino)naphthalene (DMAN) 2,4-dinitroimidazolate, C17H20N6O4, has been determined by X-ray diffraction. The crystals are monoclinic, P2 1/c, a = 13.426(4), b = 10.465(3), c = 15.915(4) », β = 126.12(4)°, Z = 4. The structure was solved by direct methods,...

A synthesis of bis-spiroacetal 13 which constitutes the bis-spiroacetal moiety of the complex marine biotoxins, spirolides 1 and 2 is described. The synthetic strategy adopted is based on assembly of a suitably protected acyclic hydroxyketone precursor. Key intermediate 25 was synthesised as a m...

The crystal structure of the adduct of 1,8-bis(dimethylamino)naphthalene (DMAN) with tetrazole (DMAN-THM), containing crystallographically symmetric NHN+ hydrogen bridges, was determined. The crystals of DMAN-THM (monohydrate) are orthorhombic, space group Pnma, with Z = 4, a = 9.500(3), b = 10....

Protonated 2,7-bis(trimethylsilyl)- and 2,7-di(hydroxymethyl)-1,8-bis(dimethylamino)naphthalenes have been prepared and studied by a combination of X-ray crystallography at room and low temperatures, IR and NMR spectroscopic techniques in conjunction with quantum-chemical calculations. It was de...

To investigate the pathologic changes of sebaceous glands during comedo formation induced by topically applied substances in a rabbit pinna model, purified tetradecane was inuncted on the ventral aspect of the rabbit pinnas once a day for a week. Histologically, a marked hyperplasia of a sebaceo...

Alkylated organophosphate esters (alkyl-OPEs) are widely used and extensively detected in aquatic organisms. This work investigated the tissue-specific toxicokinetics of two common alkyl-OPEs, tri(2‑butoxyethyl) phosphate (TBOEP) and tri‑n‑butyl phosphate (TNBP) in Chinese rare minnow (Gobiocypr...

A 1-tetradecanol (TD)/1,3:2,4-di-(3,4-dimethyl) benzylidene sorbitol (DMDBS) composite was prepared as a novel form-stable phase change material (PCM), and the properties of the composites such as the gel-to-sol transition temperature, the latent heat, the microstructure and the thermal storage ...

Mesoporous silica materials are promising nano-carriers for drug delivery systems. Even though there are many strategies for controlling the drug release kinetics, these must be adapted through trial and error on a case-by-case basis. Here we explore the possibility of tailoring the release kine...

Acylation of (±)-2,3-epoxy-1-tridecanol with acetic anhydride in diisopropyl ether by porcine pancreatic lipase yielded (2R, 3S)-2,3-epoxy-1-tridecanol as the remaining substrate with an optical purity of over 99% ee. (+)-Disparlure was synthesized in two steps from this optically active epoxy ...

Hyaluronan (HA) films exhibit properties suitable for various biomedical applications, but the solubility of HA limits their use in aqueous environments. Therefore, we developed water insoluble films based on palmitoyl esters of HA (pHA). Films were prepared from pHA samples with various degrees...

Brown adipose tissue is specialized to generate heat by dissipating chemical energy and may provide novel strategies for obesity treatment in humans. Recently, advances in understanding the pharmacological and dietary agents that contribute to the browning of white adipose tissue have been made ...

A series of palmitoyl chloride-grafted hyperbranched polyglycerols were synthesized through cationic ring-opening polymerization and end-group modification. The obtained grafted copolymer of HPG-C16 possesses a hydrophilic hyperbranched polyether core and many hydrophobic alkyl arms, which shows...