The reactions of allene gas (1 atm) and of 1,1-dimethylallene with a range protected hydroxylamines and formamide with aryl/heteroaryl iodides, bromides and triflates under Pd(0) catalysis lead to a skeletally diverse range of products in good yield. The cascades tolerate both electron withdrawi...

ObjectiveGlucagon-like peptide-1 (GLP-1) is a peptide hormone secreted by intestinal L-cells which stimulates glucose-dependent insulin secretion. GLP-1 is initially secreted as the active peptide GLP-17–36/7, but rapidly undergoes cleavage by dipeptidyl peptidase 4 (DPP4) to yield the inactive...

A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a remarkable phototoxicity and a great dose UVA de...

(1Z)-1-[2-(2-Nitrophenyl)hydrazinylidene]naphthalen-2(1H)-one (1), (4Z)-5-methyl-2-phenyl-4-(2-phenylhydrazinylidene)-2,4-dihydro-3H-pyrazol-3-one (2), (4Z)-5-methyl-4-[2-(2-nitrophenyl)hydrazinylidene]-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (3) and 3,5-dinitro-4-[(2Z)-2-(2-oxonaphthalen-1(2H)-yl...

Leachate from abandoned mine is frequently enriched with toxic elements but their off-site movement is not well addressed. In this study, the attenuation potential of mine-related metallic elements (Zn, As, and Cd) through downward soil was investigated using batch equilibrium sorption and seepa...

The first two members in the quaternary A/M/M’/Q system (A = alkaline-earth metals; M = group 12 elements; M’ = group 15 elements; Q = chalcogen), namely, the BaCd2As2S6 and BaHg2As2S6 sulfides, were synthesized via solid-state reactions. These isostructural compounds exhibit a new connectivit...

The goal of this study was to investigate the immobilization effect of vermicomposted sewage sludge for Pb, Cd and Cr in the sediment under simulated in situ conditions using column test. Positioning 10% dw of vermicompost at the bottom layer of the column resulted in an average decrease of Pb, ...

Six new transition metal phosphonates, [Cd(H2L)(H2O)]n (1), [Cd2(H2L)2(H2O)]n (2), [Cd4(H2bmt)2(H2O)]n (3), {[Cd2(H4bmt)2(2, 2′-bipy)2]·4H2O} (4), [Zn(H4bmt)(2, 2′-bipy)]n (5) and [Zn3(bmt)(4, 4′-bipy)2]n (6), H4L = (benzylazanediyl)bis(methylene)-diphosphonicacid,H6bmt = (benzene-1,3,5-triy...

The use of fertilizers and fungicides causes the accumulation of trace elements in vineyard soils that may increase their bioavailability for plants. The aims of this study were to evaluate the cadmium (Cd), copper (Cu), nickel (Ni), and zinc (Zn) accumulation and distribution in three depths of...

Zinc (Zn)-Lead (Pb) deposits are generally rich in cadmium (Cd), and the weathering of sulfide minerals in such deposits results in large releases of Cd into the environment. From an environmental and public health standpoint, understanding Cd sources and cycling is critical to identifying poten...

A new water-stable Cd coordination polymer, namely {Cd(INA)(pytpy)(OH)·2H2O}n (1, pytpy = 4′-(4-Pyridinyl)-2,2′:6′,2”-terpyridine, INA = Isonicotinic acid) had been synthesized and structurally characterized by single crystal and powder X-ray diffractions, elemental analysis, FT-IR spectros...

Three new Cd(II) complexes, [Cd2(2-aptt)2(L1)(H2O)]n (1), {[Cd3(2-aptt)2(L2)2]·4H2O}n (2) and {[Cd3(2-aptt)2(L3)]·2H2O}n (3) [2-apttH = 4-amino-3-(2-pyridyl)-1H-1,2,4-triazoleq-5-thione, H2L1 = terephthalic acid, H2L2 = isophthalic acid, H4L3 = pyromellitic acid], have been synthesized under t...

A physiscochemical model is presented for the reactive-transport of chemical scpecies through a contaminated soil during an acid-enhanced electrokinetic remediation treatment. Numerical simulations in the specific case of the removal of cadmium and lead from spiked kaolinite, compared with exper...

BackgroundThe etiology of papillary thyroid carcinoma (PTC) is unknown and some literature data support the hypothesis that heavy metals, as endocrine disrupters, could play a major role in the pathogenesis of thyroid cancer. This study aimed to estimate the content of selected toxic and essenti...

The reactivity of the allyl stannanes can be inverted by changing the oxidation state of the catalyst from Pd(II) to Pd(0). Whereas with Pd(II) an anti nucleophilic attack of the allyl stannane on the alkyne takes place, the reaction with Pd(0) proceeds by oxidative addition to form (η3-allyl)p...

Trichosporin-B-VIa (TS-B-VIa) has a Pro14-kinked helical structure which is considered to be important for the formation of peptaibol-type ion-channels in lipid bilayer membranes. TS-B-VIa and its analog [Aid14]TS-B-VIa with Pro → Aib substitution at position 14, resulting in a straight helical...

Poly(butylene succinate) (PBS) nanocomposite structure was studied as a function of the filler percentage loading. The resulting state of dispersion was evaluated by XRD and TEM, and the interfacial attrition between PBS chain and lamellar platelets by the melt rheological properties. Hybrid org...

4-Hydroxyphenyl substituted thiopyrimidine derivatives have been synthesized with the starting compound 5-benzoyl-6-phenyl-4-(4-hydroxyphenyl)-1,2,3,4-tetrahydro-2-thioxopyrimidine (1). The compounds optimized geometrically with DFT in Gaussian at the B3LYP/6-31G (d, p) level in order to obtain ...

The excited-state intramolecular proton transfer (ESIPT) dynamics of 2-(4′-Amino-2′-hydroxyphenyl)-1H-imidazo-[4,5-c]pyridine (AHPIP-c) has been studied by using density-functional theory and time-dependent density-functional theory method. Three kinds of different polar aprotic solvents, incl...

A series of arene ruthenium(II) complexes, 1a-3a, with the general formula [(η6-arene)Ru(L)Cl2] (where arene = p-cymene, hexamethylbenzene and benzene, respectively, and L = 5-(2-hydroxyphenyl)-3-methyl-1-(2-pyridyl)-1H-pyrazole-4-carboxylic acid methyl ester) were synthesized and characterized...