Publisher SummaryThe chapter discusses the synthesis and chemical properties of poly-α-amino acids. Poly-α-amino acids are synthetic polymers composed of α-amino acid residues linked by peptide bonds. They are prepared by polymerization of the corresponding monomers and consist, like other sy...

Trimethylsilyl (TMS) protecting group has been found to be very useful for the simultaneous protection of both the glycosyl donor- and the acceptor-substrates in oligosaccharide synthesis. Thus, while the per-O-trimethylsilylated glycosyl iodides served as the glycosyl donor, those bearing selec...

Jatropha curcas is a multipurpose plant, of which the seed kernel oil (up to 60% content) has been exploited for BDF production. In this report, we explored the various kinds of minor compounds of saccharides, phytochemicals, fatty acids (FAs), and amino acids in the seed kernel using gas chroma...

The interaction of bis(trimethylsilyl)ketene acetals with various pyridines provides a direct, general, diastereoselective access to fluorolactones via the formation of dihydropyridine-substituted carboxylic acids. These in turn reacted with selectfluor as the source of electrophilic fluorine. W...

The 1,3-dipolar cycloaddition reaction of fluoro(trimethylsilyl)acetylene prepared in situ with an excess of diazomethane smoothly proceeded to give the corresponding 4-fluoro-5-trimethylsilyl-1H-pyrazole in 84% yield. The copper iodide-catalyzed N-arylation of the fluorinated pyrazole with a va...

A series of novel terminal trimethylsilylacetylene benzoate derivatives with various linking groups were synthesized using Friedel-Craft's O-acylation reaction. The chemical structures of the novel 4-[2-(trimethylsilyl)ethynyl]benzoates were confirmed by standard spectroscopic techniques. T...

In this article photo-crosslinkablestyryl-pyridine modified alginate (ASP-Alg) was prepared and entirely investigated utilizing different instrumental techniques such as Elemental analysis, Fourier transform infrared (FTIR),13C and 1H nuclear magnetic resonance (NMR), ultraviolet-visible light (...

We report the synthesis and structure of a series of tantalum(V) complexes having the trimethylsilylimide moiety and using as ancillary support the pincer ligand PNP (PNP− = N[2-PiPr2-4-methylphenyl]2). Via transmetallation of Li(PNP) with Cl3(py)2TaN{SiMe3} (py = pyridine), the precursor comple...

2-Cyano-5-phenyl-3,5-dioxopentanonitrile undergoes alcoholysis followed by Knoevenagel condensation to afford ethyl 4,4-dicyano-3-phenyl-3-butenoate, a thermo dynamically controlled product, which undergoes cyclization in acid medium to afford 2,6-dihydroxy-4-phenylnicotinonitrile. Some azo deri...

The solvatochromic behavior of novel carbazole containing dyes obtained by the condensation of 9-ethyl-9H-carbazole-3-carboxaldehyde and 9-ethyl-9H-carbazole-3,6-dicarboxaldehyde with (1-phenylethylidene) propanedinitrile and ethyl-2-cyano-3-phenyl-2-butenoate are described. The dyes were charac...

Oviposition response of gravid Culex quinquefasciatus females to a series of synthetic fatty acid esters was evaluated at 10 ppm under laboratory conditions. Octyl tridecanoate and propyl octadecanoate elicited 85% and 73% increased ovipositional responses respectively, compared to control, amon...

The present work demonstrates the utility of the extended DFT-derived scaled quantum mechanical (SQM) force fields for predicting the product of a chemical synthesis, namely the reaction of 1,3-dihydrobenzimidazol-2-one with BSTFA [N,O-bis(trimethylsilyl)trifluoro-acetamid]. Since the reactant h...

ObjectiveTo investigate the effect of didrovaltrate on L-type calcium current (Ica-L) in rabbit ventricular myocytes.

(S,S)-α-fluoro-2,2-dimethyl-1,3-dioxolane-4-propanoic acid methyl ester (10), a key intermediate for the preparation of anti-HIV active 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine (1, FddA) and 1-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)cytosine (2, FddC) was prepared via t...

The white-rot fungus Pycnoporous cinnabarinus (DMS-1184) was submerged cultured for 22 days under controlled conditions in a bioreactor. After 6, 9, and 15 days of culture the growth medium was supplemented with [5-2H]-labelled ferulic acid (I). The major phenolic compounds identified labelled w...

The aldol condensation reaction between valeraldehyde and cyclopentanone was carried out in a batch reactor, at atmospheric pressure and 130 °C over “AlPON” and “ZrPON” catalysts. Those catalysts were obtained by heating AlPO4 and Zr0.9PO4.3 phosphates in a flow of gaseous ammonia at 750 an...

Supported Ni-Cr-K catalysts for hydrogenation of 2-propyl-2-heptenal was prepared by impregnation of γ-alumina first with nickel nitrate, then with potassium nitrate and chromium nitrate solution. These Ni-Cr-K/Al2O3 catalysts were studied by X-ray diffraction (XRD) and temperature-programmed r...

A novel and simple one-step method for the aluminum catalyzed self-aldol reaction of valeraldehyde is presented. This mechanochemical method utilizes high-energy ball milling to produce fresh aluminum surface in the presence of valeraldehyde as a liquid milling solution. The fresh surface create...

A high resolution study of the microwave spectrum of 2-propen-1-imine has yielded values for 14N hyperfine coupling constants for both the trans-syn and trans-anti isomers. In the latter case, evidence was found for magnetic spin-rotation interaction. Rotational and centrifugal distortion consta...

This study examined the nucleophilic addition of trichloroacetic acid to internal alkynes using RuCHPhCl2(PCy3)(IPr) (IPr: [1,3-Bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazo-2-ylidene]). This reaction was performed in good yield with high Z-selectivity under mild experimental conditions. The...