A hierarchical nanohybrid based on vertical cobalt oxide nanorods shelled with nickel oxide supported on a three-dimensional foam was prepared by a simple synthetic procedure. The unique nanoarchitecture along with superior conductivity and synergistic effect between components made hybrid becom...

The recycling of rare earth elements (REE) from end-of-life REE based products is an environment friendly proposition. Waste Sm-Co based permanent magnet generated during machining is a good source for both Sm and Co. In the present study a simpler process of acid leaching at 80 °C followed by ...

The genotoxicity of cobalt metal and cobalt compounds has been widely studied. Several publications show induction of chromosomal aberrations, micronuclei or DNA damage in mammalian cells in vitro in the absence of S9. Mixed results were seen in gene mutation studies in bacteria and mammalian ce...

Rod-shaped nanostructures of cobalt oxalate dihydrate were synthesized at room temperature by the microemulsion (reverse micellar) route. These rods are highly uniform in length and can be modified with temperature (from ∼6.5 μm at 50 °C to ∼2.5 μm at 150 °C) while keeping the diameter nea...

The magnetic properties of little examined CoBr2•2H2O and new CoBr2•H2O and CoBr2•D2O are studied. Curie-Weiss fits, χM=C/(T-θ), yield θ of −9.9, 9.4 and 10.0 K, respectively, over a 30–80 K linear range for each. Higher temperature data are fit assuming two moderately separated low lying Kr...

Reactions of MCl2·nH2O (M = Mn, Co, Ni) and 3-hydroxypyridin-2-one (dhpyH2 = C5H5NO2) afforded novel molecular complexes [MCl2(dhpyH2)4] (M = Mn (1), Co (3)) and binuclear [Co2Cl2(µ-Cl)2(dhpyH2)2(MeCN)2] (4), as well as ionic complexes [M(dhpyH2)4(ROH)2]Cl2·2ROH (R = Et, M = Co (6), Ni (8); R...

The tetrahedral Schiff base complex bis(N-isopropylsalicylaldimine)cobalt(II) [Co(saliprn)2] (CSI) was prepared by template method. The complex was characterized by FT-IR, mass spectroscopy, TG/DTA and single crystal X-ray structure determination analysis. The dynamic TG analysis showed that the...

Maternal smoking has been linked to an increased risk for orofacial clefts. N′-nitrosonornicotine (NNN) is one of the tobacco-specific nitrosamines that has been shown to be linked to the deleterious effects of tobacco and could be linked to the formation of cleft palate birth defects. The effe...

To open the new application of zeolite in health care as the capturer of nitrosamines in gastric juice, capture of N′-nitrosonornicotine (NNN) in aqueous solution by the acid-immerged zeolite is investigated in this article for the first time, facing the challenge arising from the acid immersio...

N′-Nitrosonornicotine (NNN) or N′-nitrosonornicotine-1-N-oxide (NNN-1-N-oxide), one of its metabolites, was added to the drinking water (0.012% for 36 weeks) of groups of male and female F344 rats or to the drinking water (0.016% for 31 weeks) of groups of male and female Syrian golden hamster...

Adsorption of N′-nitrosonornicotine (NNN), one of the tobacco-specific nitrosamines (TSNA), in various zeolites with different pore size and acid-basicity were studied in this paper by in situ infrared technique for the first time. The bulky NNN can be trapped by zeolite KA through the manner i...

N′-Nitrosonornicotine (NNN) is the most abundant tobacco-specific nitrosamine (TSNA) found in tobacco and tobacco smoke, and is formed by the nitrosation of nicotine, amongst other possible mechanisms. Tumor induction is believed to occur by way of 2′-hydroxylation of NNN, and others have show...

A liquid chromatography–electrospray ionization–tandem mass spectrometry (HPLC–ESI+–MS/MS) method for the analysis of the tobacco-specific carcinogens N′-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their glucuronides (total NNN and total NNAL) in hu...

We have developed a chiral stationary phase liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry (LC–NSI–HRMS/MS) method to investigate the enantiomeric composition of low parts per trillion amounts of the carcinogen N'-nitrosonornicotine (NNN) in the...

N′-nitrosonornicotine (NNN) is a strong carcinogen. The metabolic study of NNN in vivo will help us to further understand it, however, trace detection in complex matrices requires highly sensitive detection methods. After the chromatographic conditions and mass spectrometric conditions had been...

N′-Nitrosonornicotine (NNN) is considered to be one of the most carcinogenic compounds of the four conventionally measured tobacco-specific N-nitrosamines (TSNAs). In order to evaluate the significance of metabolic activation for the carcinogenic potential of NNN, its catalysis by different pha...

4-(methylintrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N’-nitrosonornicotine (NNN) are the most prevalent and toxic tobacco specific nitrosamines (TSNAs). Due to their carcinogenicity, knowledge of the composition of NNK and NNN in tobacco is necessary. Herein, a sensitive and rapid method, w...

Background & Aims: Azathioprine is the gold standard for immunosuppressive therapy in Crohn’s disease (CD) and its molecular mechanism of action is caused by the metabolite 6-thioguanosine triphosphate (TGTP). In this study we assessed the impact of TGTP levels for monitoring of azathioprine th...

Mammalian cells incorporate 6-thioguanosine into their nucleic acids when grown in the presence of 6-mercaptopurine. 35S-labeled total RNA was prepared from L5178Y murine lymphoma cells grown in vitro in the presence of 6-[35S]mercaptopurine. Base analyses of this RNA suggested that 6-thioguanos...

A fast and reliable two-step method has been established for the chemical synthesis of 6-thioguanosine 5′-monophosphate, 6-thioguanosine 5′-diphosphate and 6-thioguanosine 5′-triphosphate starting from the ribonucleoside. In the first step, 6-thioguanosine dissolved in triethyl phosphate, at ...