This research investigates the impact of glucose oxidase (GO) addition in the presence of organic acids (acetic, ascorbic, citric, fumaric, lactic, or succinic) on several parameters of a reduced salt dough system (1.0% NaCl). These parameters include dough rheology, stickiness, freezable water ...

Amylose complexes formed with fatty sodium salts were evaluated for their emulsification, foaming, and rheological properties. Amylose inclusion complexes (AIC) were produced in a pressurized microwave reactor using the sodium salts of fatty acids having carbon chain lengths of 12–22. The AIC w...

Sodium alginate (SA) and antarctic krill protein (AKP) were blended to fabricate the SA/AKP composite fibers by the conventional wet spinning method using 5% CaCl2 as coagulation solution. The sodium salt was added to the SA/AKP solution to adjust the ionization degree and intermolecular interac...

The separation of 1,3-propanediol (1,3-PD), butyric acid (BA) and acetic acid (HAc) from the fermentation broth was studied by two-step salting-out extraction. In the first salting-out extraction, the partition coefficient and recovery of BA reached 42.21 and 96.42%, respectively, under the opti...

2,3-Difluoro-4,4-dimethyl-2-buten-4-olide (1) and spirocyclic 2,3-difluoro-4,4-(pentane-1,5-diyl)-2-buten-4-olide (2) were modified by vinylic displacement of fluorine with some O- and C-nucleophiles. Sodium and lithium alkoxides, substituted phenoxides and protected glucose alkoxides reacted by...

A chiron approach for the formal synthesis of (+)-syributin 1 from d-mannitol has been described. The key steps are a Wittig reaction and RCM.

Photosensitized hydrogen abstraction from 2-alkyl-1,3-dioxolanes by triplet benzophenone gives the corresponding 1,3-dioxolan-2-yl radicals and these are trapped by α,β-unsatured ketones yielding monoprotected 1,4-diketones. With open chain ketones (3-buten-2-one and 4-penten-3-one) the yields...

Morphine is widely used for the treatment of severe pain. This analgesic effect is mediated principally by the activation of μ-opioid receptors (MOR). However, prolonged activation of MOR also results in tolerance, dependence, addiction, constipation, nausea, sedation, and respiratory depressio...

Twelve new nickel(II) complexes namely [Ni(S2CNRR′)2](1–6) and [Ni(S2CNRR′)(NCS)(PPh3)](7–12) [where R = cyclopropyl (cPr); R′ = 2HO–C6H4–CH2– (1,7), 3HO–C6H4–CH2– (2,8), 4HO–C6H4–CH2– (3,9), 4CH3O–C6H4–CH2– (4,10), 4F–C6H4–CH2– (5,11), 4Cl–C6H4–CH2– (6,12)] have been prep...

In this study, novel specific PET radioligands containing the 4-(4-fluorobenzyl)piperidine moiety and selectively antagonistic for the NR2B subunit containing NMDA receptors were developed. Two antagonists, RGH-896 (1a) and 4-(4-fluorobenzyl)piperidinyl-1-methyl-2-benzimidazol-5-ol (2a), belongi...

IntroductionEnterohepatic circulation (EHC) of conjugated bile acids is an important physiological process crucial for regulation of intracellular concentrations of bile acids and their function as detergents and signal carriers. Only few bile acid-derived imaging agents have been synthesized an...

N,O-Aminals are synthesized through the N-iodosuccinimide-mediated regioselective 1,2-additions of alcohols to allenamides. These novel reactions proceed rapidly and exhibit broad substrate scope for a variety of allenamides. The reaction demonstrates that N-Iodosuccinimide is effective in activ...

Reaction of tri(o-fluorobenzyl)tin chloride with sodium of heteroaromatic carboxylic acid in 1:1 stoichiometry yielded complexes of the type (2-F-Bz)3SnOOCR (R=2-furanyl, 2-furanvingl, 2-thiophenyl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 3-indolyl, 3-indolmethyl and 3-indolpropyl), respectively....

Imidazopyridines can exist in several tautomeric forms such as benzimidazole or purine condensed systems. Regioselectivities were determined for N-alkylations of 2-(3,4-dimethoxyphenyl)- imidazopyridines and their 4 and 5-oxides (2–4, 13, 14) with n-butyl and 4-fluorobenzyl bromides under basic...

In this study, a resin glycoside fraction with cytotoxic activity was isolated from the alcoholic extract of C. arvensis whole plants. To describe the chemical feature of the resin glycosides, the fraction was alkaline hydrolyzed and four novel glycosidic acids, named arvensic acids A-D (1–4), ...

Diol (R)-(+)-3 is prepared either from the hydroxyketone 2 by reduction with fermenting baker's yeast or by hydrolysis of the dioxolane (R)-(+)-1 which is available from dimethyl d-malate as starting material. (R)-(+)-3 could be converted stereoselectively into (R)-(+)-4. Reaction of (+)-4 ...

With the aim of designing novel transformable fatty acid diesters, various strategies for introducing phosphorus arms to the fatty backbone have been examined. While lithiated phosphine reacts classically to brominated fatty esters to afford the mono-addition product, the synthesis of phosphoryl...

4-(2H-1,2,4-benzothiadiazine-1,1-dioxide-3-yl)-2,6-bis(1,1-dimethylethyl)phenols (1–11) were prepared by cyclization of the corresponding 3,5-bis(1,1-dimethylethyl)-4-hydroxy-N-2-(sulphamoylphenyl)benzamides (12–22). Compounds 1–22 were tested as free radical scavengers by reaction with DPPH ...

The chiral intermediate (1S,2R)-[3-chloro-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid, 1,1-dimethylethyl ester 2a was prepared for the total synthesis of the HIV protease inhibitor Atazanavir. The diastereoselective reduction of (1S)-[3-chloro-2-oxo-1-(phenylmethyl)propyl] carbamic acid, 1,1-...

The experimental equilibrium tie-lines of two quaternary mixtures for (methanol + 1,1-dimethylpropyl methyl ether + toluene + 2,2,4-trimethylpentane) and (methanol + 1,1-dimethylethyl methyl ether + toluene + 2,2,4-trimethylpentane) were measured at the temperature 298.15 K and ambient pressure....