Pyridine derivative 2-hydrazino-6-methyl-4-(methoxymethyl)-5-nitropyridine-3-carbonitrile (2) has been obtained from 2-chloro-4-(methoxymethyl)-6-methyl-5-nitropyridine-3-carbonitrile (1) by novel protocol and its structure was determined by X-ray diffraction method. An analysis revealed some st...

A series of 6-aminonicotinic acid analogues have been synthesized and pharmacologically characterized at native and selected recombinant GABAA receptors. 6-Aminonicotinic acid (3) as well as 2- and 4-alkylated analogues (9–11, 14–16) display low to mid-micromolar GABAAR binding affinities to n...

Despite the widespread availability and use of dietary supplements, minimal work has been performed to assess the potential dangers many of these supplements may have on the host's well-being, in particular the host's ability to respond to infection. One supplement extensively used by ...

Creatine is pivotal in energy metabolism of the brain. In primary creatine deficiency syndromes, creatine is missing from the brain. Two of them (AGAT and GAMT deficiency) are due to impaired creatine synthesis, and can be treated by creatine supplementation. By contrast, creatine transporter de...

Dialkylmagnesium compounds (MgR2, R = C2H5, C4H9 etc.,) have drawn considerable interest in recent years due to their role in commercial polymerization reactions. Herein, we report a thorough account on the reaction intermediates involved in the synthesis of di-n-butylmagnesium from anhydrous ma...

The reaction volumes for the protonation of 4-isopropyltropolone (Hipt)(ΔVH°: Hipt+H+ ⇌ H2ipt+) ) and for the reaction of the Fe(III) ion with Hipt(ΔVFeL°: Fe3+ + Hipt ⇌ Fe(ipt)2+ + H+) have been determined spectrophotometrically in acidic aqueous media under pressure up to 250 MPa. The obta...

Species arising from Fe(II) hydrolysis in aqueous solution have been investigated using density-functional methods (DFT). The different tautomers and multiplicities of each species have been calculated. The solvation energy has been estimated using the UAHF–PCM method. The hydrolysis free energ...

The crystal structures of 1,4-diazabicyclo[2.2.2]octane (dabco)-templated iron sulfate, (C6H14N2)[Fe(H2O)6](SO4)2, were determined at room temperature and at −173 °C from single-crystal X-ray diffraction. At 20 °C, it crystallises in the monoclinic symmetry, centrosymmetric space group P21/n, ...

UV excitation of [Fe(H2O)6]3+ generates hydroxyl radicals in low quantum yield, but the events that compete with this photochemistry are obscure. To elucidate the primary events, acidic, aqueous iron(III) perchlorate solutions were studied by femtosecond pump-probe spectroscopy. We report a new ...

Enhancements in the rates of reduction of hexaaquairon(III), [Fe(H2O)6]3 +, on polycrystalline Au, Au(poly), induced by the adsorption of bromide, Br−, have been examined by chronoamperometric techniques in 0.1 M HClO4 aqueous solutions containing Br− at concentrations in the μM ( 0.15. Possibl...

The reaction of hexaamminecobalt(III) chloride with sodium tetrafluoroborate in hot aqueous medium (1:1 molar ratio) leads to formation of hexaamminecobalt(III) dichloride tetrafluoroborate, [Co(NH3)6]Cl2·BF4. This cobalt(III) complex has been characterized by elemental analyses and spectroscop...

A novel modeling procedure to accurately determine the characteristic parameters of an electrochemical reaction from polarization curves, presented in the first part of this series, is validated now on voltammetry experiments. The combination of the local polynomial model and the analytical fitt...

The energies of the 2E state in hexaammine-cobalt(II) and related complexes are estimated, and implications for the electron self-exchange reactions are discussed. Solution spectra of [Co(NH3)6]2+ and [Co(en)3]2+ are presented, and analysis of these and related spectra permits confident assignme...

The hypothesis that the electron self-exchange reaction of hexaamminecobalt(III/II) is spin-allowed and adiabatic is presented and compared to previous treatments of the reaction which considered it spin-forbidden. The hypothesis is based on the concept that since the reactant and product have t...

Eight tetrahydroisoquinoline alkaloids have been crystallized and identified from the nonphenolic and phenolic extracts of the giant Mexican cereoid cactus, Pachycereus weberi (Coult.) Br. and R. The identities were established as 5,6,7-trimethoxy-1,2,3,4- tetrahydroisoquinoline (nortehuanine) 1...

The electronic conductivity enhanced has been extensively studied and reported in lithium iron phosph-ate (LiFePO4). However, only few existing literatures are available for researchers to enhance simultaneously the ion and electronic conductivity of LiFePO4. Herein, we disclose that the LiFePO4...

One important component with particular relevance in battery performance is the cathode, being one of the main responsible elements for cell capacity and cycle life.Carbon coated lithium iron phosphate, C–LiFePO4, active material is one of the most promising cathode materials for the next gener...

Nanosized carbon-coated lithium iron phosphate (LiFePO4/C) particles were synthesized using a novel low-cost colloidal process with LiH2PO4, FeCl2 and anhydrous N-methylimidazole (NMI) as starting materials, following by a short annealing step at 600 °C. The ∼3–5 nm thick carbon coating comes...

LiFePO4 coated with nitrogen-doped carbon (NC-LiFePO4) is successfully synthesized via a simple and efficient solid state method by using nitrogen-containing ionic liquid (IL) as nitrogen source. The uniformly coated N-doped carbon layers on the particles are examined by transmission electron mi...

Nickel-rich layered cathode materials for lithium ion batteries, e.g., LiNi0.8Co0.15Al0.05O2, have garnered considerable academic and industrial research interests, due to their higher specific energy and lower cost than the widely commercialized LiCoO2. To be more widely deployed in electric ve...