The quaternary onium salt-based semiclathrate hydrates have been investigated in many kinds of fields such as latent heat storage materials and gas separation media. In the present study, equilibrium (temperature−composition) relations in the tetra-n-butylammonium 2-ethylbutyrate (TBA-2EB) semic...

The standard (p∘ = 0.1 MPa) molar energies of combustion in oxygen of 2-thiophenecarbonitrile, 3-thiophenecarbonitrile, 2-thiopheneacetonitrile, 3-thiopheneacetonitrile, and 3-methyl-2-thiophenecarbonitrile were measured, at T = 298.15 K, by rotating-bomb calorimetry. The standard molar enthalp...

This work is focused on the catalytic behaviour of alumina supported low loaded Pt-Cu catalysts. Ethylcyclopentane is the probe molecule. In fact this molecule can lead to several primary reactions as: (i) ring opening, (ii) ring enlargement, (iii) aromatisation, and (iv) hydrocracking. Due to t...

A new class of PDE4 inhibitors were designed and synthesized via the InCl3 mediated heteroarylation of indoles and their further derivatization through the Pd(II)-catalyzed CH activation strategy. This effort allowed us to discover a series of 2-(1H-indol-3-yl)-quinoxaline based inhibitors posse...

The synthesis of 6-nitro-4-sulfanyl-1H-indoles from 2,4,6-trinitrotoluene (TNT) is described. The first step is the nucleophilic substitution of an ortho-nitro group with a thiol to give the corresponding sulfide. The latter were transformed into the corresponding enamines upon treatment with di...

Reported herein is the design, synthesis, and pharmacologic evaluation of a class of TRPV1 antagonists constructed on 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole as A-region and triazole as B-region. The SAR analysis indicated that 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole analogues displayed exce...

Signal transducer and activator of transcription (STAT3) is a proposed therapeutic target for the development of anti-cancer agents. In this report, a series of N-arylsulfonylsubstituted-1H indole derivatives were designed and synthesized as STAT3 inhibitors, their anti-proliferative activities ...

A novel class of potent CCR3 receptor antagonists were designed and synthesized starting from N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide (1),which was found by subjecting our chemical library to high throughput screening (HTS). The CCR3 inhibitory activity of the synthesized comp...

The kinetic study for synthesis of 3,5-dimethyl-1-(3-phenylpropyl)-1H-pyrazole was studied successfully by reacting the 3,5-dimethyl pyrazole with 1-bromo-3-phenyl propane under phase transfer catalysis and ultrasonic irradiation conditions using aqueous solution of NaOH (5 g or 0.25 g/ml), exce...

A series of novel Y-shaped dyes bearing the D–π–A–π–D fragment comprising central 2-alkoxy-or 2-alkylthio-substituted pyrimidine core and terminal 2-(1-methyl-1H-pyrrol-2-yl)vinyl moieties have been synthesized and studied as potential materials for the organic electronics. The obtained co...

Three new mixed ligand complexes, [Hg(en)(4-pptt)2] (2) {4-pptt = 4-phenyl-5(3-pyridyl)-1,2,4-triazole-3-thione}, [Hg(en)(4-pot)2] (3) {4-pot = 5-(4-pyridyl)-1,3,4-oxadiazole-2-thione} and [Ni(en)2(5-thot)2] (4) {5-thot = 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-thione}, have been prepared containin...

The compound has been synthesized and characterized by IR, NMR and X-ray diffraction. Quantum chemical calculations at B3LYP/6−311++G(d,p) level were performed to study the molecular and spectroscopic properties, conformational equilibrium, thione ↔ thiol tautomerism and intermolecular double pr...

Tetrabutyl ammonium bromide (TBAB) has been demonstrated to be a very effective reagent for selective extraction of anionic dyes from aqueous solution. The solution of TBAB in methylene chloride is able to extract 98% of 50 mg L−1 concentration of dye solution. The distribution ratio is reasonab...

In this work, based on the van der Waals–Platteeuw (vdW–P) theory, a thermodynamic approach is proposed to determine the phase equilibria of semiclathrate hydrates formed with tetrabutyl ammonium halide (fluoride, chloride, or bromide) and guest gas (CH4 or CO2). The Peng–Robinson equation of...

The extraction of hexavalent chromium (Cr) from aqueous solutions by tetrabutyl ammonium bromide (TBAB) salt in dichloromethane was investigated. The results indicated that the maximum extraction efficiency of Cr(VI) was at pH 1±0.1. The strippant 0.1 M sodium hydroxide, completely stripped Cr(...

Electro-Electrodialysis (EED) as a novel technology would effectively enable the preparation of Tetrabutyl Ammonium Hydroxide (TBAOH) from Tetrabutyl Ammonium Bromide (TBABr). In this work, NaOH and NH3·H2O of alkaline electrolyte were selected as anode solution to reduce the operating voltage,...

The densities of tetra-n-butylammonium bromide in 1-propanol, 1-butanol, acetone at (288.15, 293.15, 298.15, 303.15, 308.15, 313.15, and 323.15) K and sound velocities at 298.15 K have been measured. From these data apparent molar volumes VΦ at (288.15, 293.15, 298.15, 303.15, 308.15, 313.15, a...

The solubility of SO2 in a binary mixture of water and caprolactam tetrabutyl ammonium bromide ionic liquid (CPL-TBAB IL) was investigated. Though the ionic liquid and water were fully miscible, a phase separation occurred when SO2 was introduced into the mixture. The SO2 concentrated in the low...

Michael addition reactions of cyclic β-oxo ester and α-methyl cyano ester substrates with acceptor activated olefins were catalyzed by iron N−heterocyclic carbene (NHC) complexes of the type, {Cp[1-benzyl-3-alkyl-benzimidazol-2-ylidene]Fe(CO)2}I, where [alkyl = i-Pr (1) and Et (2)] in the pres...

Vapour state Raman spectra with polarization data are reported for sulphur dichloride and disulphur dichloride. A heated Raman vapour cell for use over the temperature range 300–700 K is described. Complete vibrational assignments for sulphur dichloride and disulphur dichloride in the vapour st...