The competitiveness of concentrated solar power technology in the near-future electricity generation scenario, requires a substantial reduction of the Levelized Cost of Energy which can be achieved with an increase of the energy conversion efficiencies while maintaining or reducing the investmen...

This article presents the results of field and laboratory experiments performed to determine the compositions of gases in the air above the Komsomolsk sulfide tailings. Concentrations of SO2 were measured using a GANK-4 portable gas analyzer. The possibility of the gaseous transport of trace ele...

Field-swept 33S NMR spectra of a cyclic octaatomic molecule of elemental sulfur, α-S8, are presented. The spectra were acquired at a Larmor frequency of 16.2 MHz and using a superconducting magnet at between 6.32 and 0.50 T. Methods were developed for analyzing the field-swept 33S NMR spectra i...

The sulphur aroma compounds produced from a phosphate-buffered solution (pH 8) of l-cysteine and l-, l-[1-13C] or l-[4-13C] ascorbic acid, heated at 140 ± 2 °C for 2 h, were examined by headspace SPME in combination with GC–MS. MS data indicated that C-1 of l-ascorbic acid was not involved in...

Post-treatment with 2% H2O2–0.2% tetraacetylethylenediamine (TAED) at pH 11.8 for 12 h at 48 °C solubilized 27.1–28.1% of the original hemicelluloses and 43.3–46.2% of the original lignin from the ultrasound irradiated and alkali pre-treated wheat straw. It was found that the bleaching activ...

The dark degradation of tetraacetylethylenediamine (TAED) was investigated. It is a slow process which is favored in acidic medium. There is a hydrolysis of an imide group with the scission of the CN bond giving rise to the triacetyl derivative (TAED'). When allowed to stand for longer ti...

Treatment of chemical warfare agents (CWAs) including soman (GD), mustard (HD) and VX by combined sodium percarbonate and tetraacetylethylenediamine (SPC/TAED) solution was investigated. The optimal pH value for the degradation of HD and VX were about 7.5–9.0 and 8.5–9.5, respectively. The dec...

The solubility of pharmaceutical and bioactive compounds, such as N-acetyl-l-cysteine, isoniazid, pyrazine-2-carboxamide, coumarin, 4-hydroxycoumarin, 4′-isobutylacetophenone, ibuprofen and thymoquinone, was tested in trihexyl(tetradecyl)phosphonium chloride. Hydrophobicity/hydrophilicity featu...

Coumarin sulfonates 4–43 were synthesized by reacting 3-hydroxy coumarin 1, 4-hydroxy coumarin 2 and 6-hydroxy coumarin 3 with different substituted sulfonyl chlorides and subjected to evaluate for their in vitro immunomodulatory potential. The compounds were investigated for their effect on ox...

2,7-Diethylamino-2-oxo-2H-chromen-3-yl benzothiazole-6-sulfonyl chlorides dye (Coumarin 6-SO2Cl) was used to synthesize anilines and amino acid derivatives.The electronic absorption and emission spectra of the label and its derivatives in organic solvents of different polarity, micellar systems ...

A simple, sensitive and rapid reversed-phase high-performance liquid chromatography (RP-HPLC) method is proposed for the analysis of some environmentally important phenols in water. The use of coumarin-6-sulphonyl chloride (C6SCl) as a fluorescence-labeling reagent has been investigated. The com...

N,O-Bistrimethylsilyl-4-aminobenzoic acid was selectively acylated at the amino group with 4-acetoxy-3-methoxybenzoyl chloride. The resulting dimer with silylated carboxyl group was polycondensed in situ at 300 or 350°C using Marlotherm-S as an inert reaction medium. In an alternative approach ...

The in vivo metabolism of the xenobiotic agent 2-ethylhexyl 4-(N,N-dimethylamino)benzoate (EDP), a UV filter commonly used in sunscreen cosmetic products, was studied by targeting metabolomics analysis in human urine. The metabolomic study involved the use of urine from male and female volunteer...

Both (R)- and (S)-2-N-methylamino-2,3-dimethylbutanamides have been prepared by the reductive benzylation of (R)- and (S)-2-amino-2,3-dimethylbutanamides, followed by reductive methylation and hydrogenolytic removal of the benzyl group. The reductive benzylation is chemoselective, and not accomp...

We report on an extension of our previous discovery of in vitro anticancer activity of trifluoromethylquinoxalines as analogues of classical and non-classical antifolic methotrexate and trimetrexate. In this case a small number of Schiff bases were obtained from the reaction of 2-bromethyl-3-R-6...

In this study, we synthesized and evaluated several amino 4-hydroxy-2(1H)-quinolone (4HQ) derivatives as new PET radioligand candidates for the glycine site of the NMDA receptors. Among these ligands, we discovered that 7-chloro-4-hydroxy-3-{3-(4-methylaminobenzyl) phenyl}-2-(1H)-quinolone (12) ...

3-(tert-Butyl)-4-hydroxyphenyl 2,4-dichlorobenzoate (1) was discovered in our in-house high throughput screening as a moderate FXR antagonist. To improve the potency and the stability of the hit 1, forty derivatives were synthesized and SAR was systematically explored. The results turn out that ...

Due to the lack of regulated drugs for aquaculture, the present study considered specific issues relating to environmental and food safety aspects concerning the potential use of emamectin benzoate (EMA) in freshwater fishes such as tilapia (Oreochromis niloticus) – an important commercial fish...

While gem-dichloromethyl groups can be directly synthesized by the mono-dechlorination of the corresponding trichloromethyl groups, the suppression control of the over-reduction to form chloromethyl or methyl functionalities is quite difficult. We have established the efficient and widely applic...

o-Toluidine hydrochloride and one of its metabolites, o-nitrosotoluene, were administered in the diet (0.028 mol/kg diet) to 2 groups of 30 male F-344 rats for 72 weeks. o-Nitrosotoluene induced significantly more tumors of the bladder (1630 rats) and liver (2030) than did o-toluidine hydrochlor...