The respective effects of 2-chloropropionate and dichloroacetate on the pyruvate metabolic crossroads, lipogenesis and ketogenesis, were compared in hepatocytes isolated from fed rats. 2-Chloropropionate acts as an exclusive pyruvate dehydrogenase activator: it increases ketogenesis, lipogenesis...

Dichloroacetate, an activator of the pyruvate dehydrogenase complex, is known to lower blood glucose, lactate, pyruvate, and alanine when given to diabetic and 24 h fasted rats. Under certain conditions, especially when pyruvate carboxylase is made rate limiting for want of bicarbonate, dichloro...

(S)-2-Chloropropionate is a synthetic intermediate for phenoxypropionic acid herbicides. We constructed a system for asymmetric reduction of 2-chloroacrylate to produce (S)-2-chloropropionate with recombinant Escherichia coli cells producing 2-haloacrylate reductase from Burkholderia sp. WS and ...

Heat capacities of methylammonium hexabromotellurate (IV) and methylammonium hexaiodotellurate (IV) have been measured between 13 and 320 K. Three anomalies were found for the bromotellurate. Their temperatures and entropies are as follows 129.0 K (13.0 JK−1mol−1), 163.9 K (5.4 JK−1 mol−1) and 2...

The distribution behavior of ion associates (Q+)2. TeBr62− of TeBr62− with quaternary ammonium cations (Q+) between aqueous phase and two organic phases (1,2-dichloroethane (DCE) and chloroform (CF)) was examined, and the extraction constants (log Kex) were determined. The extractability with lo...

Lysophosphatidic acid (LPA) plays an important role in a variety of cellular functions. In particular, LPA5 receptor is highly expressed in spinal cord and dorsal root ganglion, which are associated with pain. This fact prompted us to hypothesize that LPA5 antagonists show analgesic effects. To ...

The interaction of gaseous ammonia on anhydrous uranyl formate has been studied. Depending on the temperature, three different compounds can be obtained: UO2(HCOO)2 · 2NH3(A), UO3 · 2HCONH2 · H2O(B), UO3 · HCONH2 · H2O(C). A is unstable at room temperature, and transforms into B, which lead...

The protonation of benzoate and the complexation of uranyl monobenzoate in NaClO4 solutions ranging from 0.1 to 0.5 M were quantitatively investigated by means of ultraviolet–visible (UV–Vis) spectrophotometry. The spectrophotometric study revealed that the uranyl monobenzoate species has a si...

The resonance Raman scattering spectra of uranyl formate (UO2(HCOO)2) in dimethyl sulfoxide ((CH3)2SO, DMSO) have been measured under laser excitation of the uranyl ion in resonance with the 1Σg+→1Φg Laport forbidden f–f electronic transitions (ranging from 510 to 450 nm) by using ten output...

Protein glycation via the Maillard reaction is widely used to modify the functional properties of proteins. Using four explored reaction conditions, two maltose-glycated caseinate products GCN-I and GCN-II with maltose contents of 30.86 and 8.76 g/kg protein were prepared by this reaction in an ...

Saccharomyces cerevisiae expresses α-glucoside transporters, such as MalX1p (X = 1(Agt1p), 2, 3, 4, and 6), which are proton symporters. These transporters are regulated at transcriptional and posttranslational levels in the presence of glucose. Malt wort contains glucose, maltose, and maltotri...

The T9W is a variant of pig myeloid antimicrobial peptide-36 (PMAP 36) that displays efficient and specific activity against Pseudomonas aeruginosa. It may represent a promising agent for anti-pseudomonas therapies, so a large quantity of T9W is needed for pharmacological study and clinical use....

The rheological behavior of blends of a fractionated maltopolymer (Mw = 1.4⋅104 Da) and the disaccharide maltose is investigated as a function of water content and temperature, with emphasis on the viscosity and molecular relaxations in the approach to the glass transition. Shear rheology is com...

The objective of this study was to determine the effect of pH on the growth rate and production of pigments by Monascus ruber from maltose syrup residue as a substrate. The cultivations were carried out in solid and submerged media under different pH conditions. The highest radial growth rate oc...

A novel α-amylase gene (TdAmyA) with an open reading frame of 1431 bp, deducing 476 amino acids, was cloned from the thermophilic fungus Thermomyces dupontii L18. The recombinant α-amylase was successfully over-expressed in Pichia pastoris. The highest α-amylase activity of 38,314 U/mL was ob...

Maltose frequently occurs as intermediate of the central carbon metabolism of prokaryotic and eukaryotic cells. Various mutants possess elevated maltose levels. Maltose exists as two anomers, (α- and β-form) which are rapidly interconverted without requiring enzyme-mediated catalysis. As malto...

Poly(propylene imine) dendrimers have been shown to be promising 3-dimensional polymers for the use in the pharmaceutical and biomedical applications. Our aims of this study were first, to synthesize a novel type of dendrimer with poly(propylene imine) core and maltose-histidine shell (G4HisMal)...

The change in structure, function of proteinase K in the presence of maltose was studied using spectroscopic and computational techniques. UV–Vis spectroscopy results reveal with the addition of maltose, the peaks of proteinase K didn't show any shifts. The intrinsic fluorescence intensity...

In light of a recent update in EU regulations governing levels of acrylamide in foodstuffs, further understanding of the role of different precursors is fundamental to extending mitigation strategies into a wider product range. Kinetic modelling was used to investigate the role of maltose in the...

Manganese(II) perchlorate and iron(II) chloride react with 2-formylpyridine semicarbazone (HCSpy) in boiling ethanol to produce [MnII(HSCpy)2](ClO4)2·C2H5OH and [FeIICl(HSCpy)]Cl. The distorted octahedral manganese complex crystallizes in the triclinic system with space group P(-1). The ligand ...