Previous research has identified METCAM/MUC18, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family, as a promoter or a suppressor in the development of human breast cancer by MCF7, MDA-MB-231, and MDA-MB-468. To resolve these conflicting results we have investigate...

Theoretical calculations of Ga-like to Br-like gadolinium ions were performed by using the fully relativistic multi-configuration Dirac–Hartree–Fock (MCDHF) method. Extensive lists of excitation energies, wavelengths, line and oscillator strengths, and E1, M1, E2, M2, and E3 transition rates a...

Fluid inclusions in quartz samples from a miarolitic cavity, two quartz veins, and a hydrothermal ore vein in the Tsushima granite, Japan, were analyzed by particle-induced X-ray emission to examine the chemistry and process of formation of hydrothermal fluids in an island-arc granite. Most of t...

Luminescence and scintillation properties of Bi3+, Sb3+, and Eu2+-doped LaI3 and LaBr3 were explored. Out of the three dopants investigated, Eu2+ was the most promising new activator for small-bandgap LaX3 (X = Br, I) and was further studied in the mixed-halide LaBr3−xIx. Crystals were grown fro...

Cases of honey poisoning have been reported widely, meaning there is a need for methods that detect “mad honey” or honey contaminated with plant-derived toxins to protect human health. In this study, we compared whole flower extracts and honey from Tripterygium wilfordii Hook. f. (TwHf) and Ma...

BRASSINAZOLE RESISTANT 1 family proteins (BZRs) are central transcription factors that govern brassinosteroid (BR)-regulated gene expression and plant growth. However, it is unclear whether there exists a BZRs-independent pathway that mediates BR signaling. In this study, we found that knocking ...

A sensitive and selective method was developed for the separation and characterization of related substances (RSs) in EVT-401 by hyphenated LC–MS techniques. Complete separation of the RSs was achieved with an Inertsil ODS-SP column (250 mm×4.6 mm, 5 µm) by linear gradient elution using a mob...

We synthesized novel phenylenediamine derivatives and evaluated them as labeling agents to label proteins in close proximity to a single electron transfer catalyst. We found that N’-acyl-N-methylphenylenediamine labels tyrosine effectively in a model experiment using tris(bipyridine)ruthenium (...

Estrogens are the major female sex steroid hormones, estradiol (E2) being the most potent form in humans. Disturbing the balance between E2 and its weakly active oxidized form estrone (E1) leads to diverse types of estrogen-dependent diseases such as endometriosis or osteoporosis. 17β-Hydroxyst...

Several N-prolinylanthranilic acid derivatives were prepared and tested as bifunctional organocatalysts in the direct asymmetric aldol reaction of cyclohexanone with p-nitrobenzaldehyde. It was found that methyl substitution ortho to the carboxylic acid improves enantioselectivity, but substitut...

Pincer ligands have proven to be valuable tools in the formation of robust transition metal complexes. To date, pincer ligands have featured an extremely diverse array of structural motifs, backbones and donor units. Carbene ligands have been easily integrated into a variety of pincer ligand str...

Among 14 bis-halomethylated naphthalenes and quinolines, 2,6-bis(bromomethyl)naphthalene was found to have highly active crosslinking activity on DNA. The unique behavior of high microbial mutagenicity, even though it had a low propensity to form double-strands in linearized plasmid DNA, suggest...

Tight junctions (TJs) alteration is commonly seen in airway inflammatory diseases. Oncostatin M (OSM) is an inflammatory mediator associated with chronic rhinosinusitis with nasal polyps (CRSwNP). We have previously shown that human nasal epithelial cells (hNECs) are highly permissive cells for ...

Oncostatin M (OSM), an inflammatory cytokine belonging to the interleukin-6 (IL-6) superfamily, plays a vital role in multitude of physiological and pathological processes. Its role in breast tumor progression and metastasis to distant organs is well documented. Recent reports implicate OSM in m...

Novel N,O-bidentate BF2 and BPh2 complexes have been prepared in good to excellent yields through coordination of 8-hydroxy-2-methylquinolines and 2-(2-hydroxyphenyl)-3Н-quinazolin-4-ones with boron trifluoride etherate or triphenylborane under mild conditions. All complexes have been character...

Two kinds of pyrocatechols, pyrocatechol (CL) and nitropyrocatechol (NCL), were chosen by the conductive value change (Δ) they cause in the boric acid-polyol solutions, and corresponding modified resins (CL-RESIN and NCL-RESIN) were synthesized by new methodology for effective boron removal and...

A convenient and an efficient method for the synthesis of 14-aryl-14H-dibenzo [a,j] xanthenes and bis(naphthalen-2-yl-sulfane) derivatives is described. The reaction proceeded via condensation of aldehydes with 2-naphthol or 2-thionaphthol in the presence of polyvinylpolypyrrolidone-supported bo...

The synthesis of salen/salan ligands (L1 and L2) and their fluorine/phenyl chelated boron complexes [L(1,2)BF2] or [L(1,2)BPh2] is described in this paper. The fluorine/phenyl chelated boron complexes were synthesized from the reaction of BF3·OEt2 or BPh3 with the corresponding ligands in diffe...

Inorganic fillers are widely used for epoxy resins to improve mechanical and thermal properties. However, inorganic fillers may unexpectedly affect the curing reactions of such epoxy resins. In our present study, influences of inorganic fillers on the curing reactions of phenol novolac epoxy res...

Novel N,O bidentate BF2 complexes were prepared in good to excellent yields through the coordination of (2-quinolin-2-yl)phenol and its derivatives with boron trifluoride etherate under mild conditions. These fluorine–boron complexes exhibited strong fluorescence both in organic solvents and in...