Cyanostilbene has been widely used in the design of photoelectrical materials, and our previous work has confirmed its Z/E isomerization reaction under photoirradiation can be suppressed by forming a suitable donor-acceptor (D-A) structure. In this work, we report two D-A cyanostilbene derivativ...

The one- and two-dimensional 15N, 13C and 1H NMR spectra of benzenediazonium chloride coupling product with 3-methylquinoxalin-2(1H)-one were measured and analysed. It was convincingly proved that two components of the reaction product obtained by coupling reaction are 3-[(Z)-(2-phenylhydrazinyl...

This paper presents the heat transfer coefficients and the frictional pressure drops of R1234ze(Z) and R1233zd(E) boiling inside a commercial Brazed Plate Heat Exchanger (BPHE): the effects of heat flux / mass flux, saturation temperature / pressure, outlet conditions and fluid properties are in...

Complex of rhodium(III) with acetylacetone (Rh(acac)3) was synthesized, purified and identified for thermochemical study. Vapor pressures of the compound were measured by static and transpiration methods in the temperature range from 398 to 521 K. Thermodynamic characteristics of sublimation pro...

The physicochemical properties of the base and hydrochlo-ride salt of the poorly water-soluble drug α-pentyl-3-(2-quinolinylmeth-oxy)benzenemethanol (REV 5901) were investigated in order to select an appropriate form of the drug for dosage form development. The pH-solubility profiles of both th...

BackgroundCervical preparation has been shown to reduce complications with dilatation and evacuation (D&E), but the optimal regimen is unknown. While most published reports are from North America and describe overnight cervical preparation, recent research suggests the safety of same-day cervica...

ObjectiveThe objective of the study was to test the hypothesis that Dilapan-S is not inferior to the Foley balloon for preinduction cervical ripening at term.

Two complexes [(L)2MnII(OClO3)(CH3CN)](ClO4)·CH3CN (1) and [(L)4MnIII/IV2(μ-O)2](ClO4)3·2CH3CN·Et2O (2), where L is 2-((1H-pyrazol-1-yl)methyl)-1-methyl-1H-benzimidazole, have been synthesized, structurally characterized, UV–Vis and EPR spectral properties, variable-temperature (2–300 K) m...

Structure–activity relationship studies in a series of diarylpyrazolyl thiadiazoles identified cannabinoid-1 receptor antagonists with excellent potency and selectivity. Based on its exceptional in vivo efficacy in animal models and its favorable pharmacokinetic and toxicological profiles, 2-(4...

A combined theoretical and experimental study on the structure, infrared and UV–Vis data of 2-{(E)-[(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)imino]methyl}phenol (3), is presented. Theoretical geometry optimization and its IR spectrum were carried out using the Density Functional Theory (DFT), whi...

In this paper, theoretical and experimental studies of two new Schiff bases were performed. The (E)-2-{[(5-(tert-butyl)-1H-pyrazol-3-yl)imino]methyl}phenol (3) and (E)-2-{[(1-(4-bromophenyl)-3-(tert-butyl)-1H-pyrazol-5-yl]imino]methyl}phenol (5)compounds were characterized by spectroscopic techn...

The oxygen exchange reactions of kojic acid and γ-pyrone were carried out in aqueous neutral, acidic and basic solutions. The incorporation of 18O in kojic acid is similar to that of γ-pyrone and the incorporation into the ring oxygen was observed. The exchange reactions of pyromeconic acid, m...

Publisher SummaryThe kojic acid, 5-hydroxy-2-(hydroxymethy1)-4H-pyran-4-one is produced from carbohydrate sources in an aerobic process by a variety of microorganisms. Kojic acid was first reported as a crystalline substance from the mycelia of Aspergillus orgzae grown on steamed rice. Kojic aci...

With the aim to design new chelators for the clinical treatment of different diseases involving the trivalent metal ions Fe(III) and Al(III), we present the equilibria of kojic acid and its derivative 6-[5-hydroxy-2-hydroxymethyl-pyran-4-one]-5-hydroxy-2-hydroxymethyl-pyran-4-one with these two ...

Direct and non-direct conjugation of kojic acid with chitosan was carried out according to the following approaches: (a) covalent binding of chlorokojic acid to chitosan via free amino groups, and (b) complexation of kojic acid with iron(III) bound to chitosan. Obtained products were analysed by...

Kojic acid is a high consumption additive and antioxidant in food samples such as fresh vegetables. Therefore, we focus for analysis of this antioxidant in the present study. In the present research, the ability of carbon paste electrode modified with V2O5 nanoparticle (V2O5/NPs) and n-hexyl-3-m...

A new water-soluble luminescent complex of europium with an organic ligand bearing di(phosphonomethyl)amide moiety has been synthesized and characterized by NMR spectroscopy and HRMS-ESI analysis. Its luminescence quantum yield is 4.7 and 1.2%, and luminescence lifetime is 0.7 and 0.5 m in metha...

The scintillation properties of K2LaX5 (X=Cl, Br, I) doped with 0.7% and 10% Ce3+, studied by means of X- and γ-ray excitation are presented. Under X-ray excitation, Ce3+ emission is observed. At 100 K, it is peaking at 344 and 372 nm in the chloride, at 359 and 391 nm in the bromide, and at 40...

Neoplasms of the son tissue range from benign, indolent tumors to some of the most aggressive malignancies known to man. Despite exhaustive studies detailing their occurrence elsewhere within the body, there has been relatively little detailing such neoplasms arising within the son tissues of th...

The effect of MK-401 (4-amino-6-trichloroethenyl 1,3-benzenedisulfonamide) on Fasciola hepatica phosphoglycerate kinase (EC 2.7.2.3) was investigated. MK-401 was a competitive inhibitor of both 3-phosphoglycerate and ATP and had a Ki of 0.29 mM. ATP, 1,3-diphosphoglycerate and MK-401 protected t...