Mixed ethyl phenylurethane/titania particles were obtained by the hydrolysis of phenylisocyanate-titanium ethoxide aerosol droplets. Chemical composition, structural and phase changes, studied by differential scanning calorimetry, thermogravimetry and X-ray diffractometry, were investigated on u...

Chemoselective reduction of the carbonyl group in α-acyl-N-[Bis(methylthio)methylene]-alaninates 1a-c and phenylalaninates 1d,e allowed for the diastereoselective synthesis of both the syn and the anti isomers of the corresponding N-protected α,α-disubstituted β-hydroxy-α-amino esters 2. Th...

The mass spectrometric fragmentation of (S, S)-N, N′-bis[1-(hydroxymethyl) alkyl] anthracene/naphthalene-1, 8-dicarboxamides was investigated with the aid of mass-analyzed ion kinetic energy spectrometry and the elemental compositions of important fragment ions were determined by accurate mass ...

N,O-bis(diphenylphosphinyl)-2-(hydroxymethyl)aziridine (‘DiDpp’, 1) is efficiently prepared from 2-aminoethane-1,3-diol: this activated aziridine undergoes two sequential reactions with copper(I)-modified Grignard reagents, yielding α-branched N-Dpp amines in good yield.

The direct preparation of chiral 2,2′-bipyridine bis-N-oxides has been developed. The method involves two stages, first, the deprotonation of substituted chiral pyridine N-oxides and second, the oxidative dimerization of the resulting 2-lithiopyridine N-oxides. Optimization of the reaction cond...

A Cu(I)-catalyzed asymmetric aziridination of styrenes with a chiral N-tosyloxycarbamate has been developed. Double stereodifferentiation was observed and both the N-tosyloxycarbamate substituent and the bis(oxazoline) ligand have a significant effect on the yields and diastereoselectivities. Th...

The acid-base properties of N,N′-disubstituted dithiooxamides derived from alkyl-α-aminoacids or glycylglycine were studied in aqueous solutions of pH 2.5-10.8. For each dithiooxamide, protonation constants were obtained from potentiometric data for three dilute aqueous solutions [I=0.15 M (Na...

Treatment of metalloligand [Ni(tsalphen)] (tsalphen = N,N′-bis(2-thiobenzylidene)-1,2-phenylenediaminato) with [(η6-p-cymene)RuCl(μ-Cl)]2 or [CpRu(PPh3)2Cl] afforded cationic “Ni(μ-S)2Ru” bimetallic complexes [(η6-p-cymene)Ru{Ni(tsalphen)}(MeCN)](OTf)2 (1) and [CpRu{Ni(tsalphen)}(PPh3)]2(...

Herein, iron-rich Sinai clay (ATT) was chemically-modified by inventive azacoumarin (Az), spiropyrrolidine (Sp) and imidazothiadiazole (Im) compounds forming clay-containing hematite particles. Interplay between the chemistry of organo-compounds and the clay-sheet structure was interpreted by ru...

The enantiomers of a variety of N-alkyl-, N-aralkyl-, and N-cyclopropylalkyl-9β-hydroxy-5-(3-hydroxyphenyl)morphans were synthesized employing cyanogen bromide and K2CO3 to improve the original N-demethylation procedure. Their binding affinity to the μ-, δ-, and κ-opioid receptors (ORs) was ...

A simple three-step synthesis of 5-(3-hydroxyphenyl)-2-methyl-2-azabicyclo[3.3.1]nonan-4-ol (3a) was achieved using an osmium tetroxide mediated oxidation of the known intermediate 6. A pyrrolidine-ring variant of 3a (3-(7-(hydroxymethyl)-6-methyl-6-azabicyclo[3.2.1]octan-1-yl)phenol (5)) was is...

ZusammenfassungAus den Samen von Holocalyx balansae Mich. wurde durch Chromatographie an Kieselgel Holocalin, ein neues cyanogenes Glykosid, isoliert. Holocalin wird durch Emulsin in Glucose, Cyanwasserstoff und m-Hydroxybenzaldehyd gespalten. Laut optischem Drehwert repräsentiert es das Diaster...

The vibrational assignment and analysis of the fundamental modes of the compounds acetoacetanilide (AAA), 2-chloroacetoacetanilide (2CAAA) and 2-methylacetoacetanilide (2MAAA) have been performed. Density functional theory studies have been carried out with B3LYP method utilising 6-311++G** and ...

In this study, a 200-day deca-brominated diphenyl ether (deca-BDE) degradation activity experiment was carried out, using consumer-use curtain material as the substrate. During the degradation process, polybrominated diphenyl ether (PBDE) products with fewer bromine atoms were gradually generate...

We demonstrated the facile synthesis of a new class of functionalized polyethylene containing precisely sequenced diphenyl ether moieties via acyclic diene metathesis (ADMET) polymerization of a series of α, ω-diene monomers (M1-M3) with central diphenyl ether segments and subsequent exhaustiv...

SummaryBackgroundPolybrominated diphenyl ethers (PBDEs) are widely used flame retardants, and their endocrine-disrupting properties have focused growing attention regarding their teratogenic potential. We have recently documented that mothers of children born with hypospadias had been exposed to...

The sorption of polybrominated diphenyl ethers (PBDEs) onto polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyamide (PA) microplastics was analyzed using different kinetic and isotherm models, and under various environmental conditions, including temperature, pH, salinity and diss...

Contaminated land and groundwater remediation in military waste dumping sites often necessitates the use of simple, cost-effective, and rapid tests for detecting trinitrotoluene (TNT) residues in the field along with their dinitro-analogues. A simple, rapid, low-cost, and field-adaptable (on-sit...

Dicyclohexylamine, a spermidine synthase inhibitor, was evaluated for its ability to alter specific polyamine levels in rat hepatoma HTC cells in culture. Media concentrations of 0.5 and 1.0 mM reduced the production of spermidine from putrescine and enhanced the conversion of existing spermidin...

In the reaction between 3,5-dinitrosalicylic acid and urotropine, the proton of the phenolic group is transferred to a nitrogen atom of urotropine to form a hydrogen-bonded ion-paired [N⋯Ophenolate=2.777(4)Å] compound. An analogous reaction between the acid and dicyclohexylamine yields a centro...