The electrochemical behavior of 3,4-dihydroxyphenylacetic acid (DOPAC) in aqueous solutions with different pHs and DOPAC concentrations was studied by cyclic voltammetry at various potential scan rates. The electro-oxidation of DOPAC involves a transfer of two electrons and two protons in soluti...

The conformational space of 3,4-dihydroxyphenylacetic acid (DOPAC), an important dopamine metabolite, has been investigated by quantum chemical methods (B3LYP and MP2, with the 6-311++G(d,p) basis set) and matrix-isolation infrared spectroscopy. Detailed analysis of the calculated potential ener...

The densities, ρ, speeds of sound, u of 1-ethyl-3-methylimidazolium tetrafluoroborate (i) + aniline or N-methylaniline or 2-methylaniline (j) binary mixtures at 293.15, 298.15, 303.15, and 308.15 K and excess molar enthalpies, HE of the same mixtures at 298.15 K have been measured over entire m...

The preparation and characterization of CuMe2DBEnX2 (X = Cl,Br,NO3; Me2DBEn = N,N′-dimethyl-N,N′-dibenzylethylenediamine); CuMe2DBEn(H2O)2SO4; [CuMe2DBEn(OH)]2(ClO4)2 and NiMe2DBEn(NO3)2 are reported. Reflectance spectra, magnetic susceptibilities, IR spectra, X-ray powder patterns and molar c...

A novel series of mixed-ligand platinum(II) complexes of the type [PtCl(DMSO)(L)], where HL=N,N-diethyl-N′-(3-R-benzoyl)thiourea, N,N-di(2-hydroxyethyl)-N′-(3-R-benzoyl)thiourea or N-morpholino-N′-(3-R-benzoyl)thiourea (R=H, Cl, NO2, CH3O, CH3), have been synthesised and characterised by elem...

p-Toluenesulfonyl chloride (TsCl)/NaOH has been introduced as reagent combination for the synthesis of 2-amino-oxa- or 2-amino-thiazolidines from N-(2-hydroxyethyl)-thioureas, but its general application in heterocycle synthesis has not been investigated. In this paper the convenient and efficie...

The crystal and molecular structure of hydrophilic N,N-di(2-hydroxyethyl)-N′-benzoylthiourea (H3L4) has been determined. This ligand coordinates to Pt(II), Pd(II) and Ni(II) in a bidentate manner yielding essentially neutral complexes of the type cis-[Pt(H2L4)2]. By contrast, N-(2-hydroexyethyl...

The preparation of a new family of lipothiourea is reported using an automatic synthetic workstation. In these compounds the headgroups were made from single thiourea derivatives. The physicochemical properties and the transfection efficiency of several members of the family were studied. It was...

2-Phenylaminothiazolines 3 were synthesized from N-(2-hydroxyethyl)-N′-phenylthioureas 2 by a one-pot reaction using p-toluenesulfonyl chloride (TsCl) and NaOH or Et3N.

A convenient synthesis of N,N-disubstituted 4H-3,1-benzothiazin-2-amines from aryl(2-isothiocyanatophenyl)methanones using a two-pot procedure has been developed. Thus, treatment of these isothiocyanato ketones with secondary amines gave the corresponding keto thioureas, which were allowed to re...

A novel rhodamine-based turn-on fluorescent probe with three thiourea receptors was designed, synthesized and fully characterized. In acetonitrile/4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid buffer (9/1, v/v, pH = 7.21), the probe showed high selectivity and sensitivity to Hg2+ with a 20-...

A series of new [1,2,3]triazolo[4,5-d]pyrimidine/thiourea hybrids were designed and synthesized through the scaffold replacement/ring cleavage strategy. SARs studies revealed that the N-heteroarene moiety attached to the thiourea is preferred over the phenyl ring for the R2 substituents, while t...

2-Methylaminothiazolines 3 were synthesized selectively from N-(2-hydroxyethyl)-thioureas 2 by the intramolecular Mitsunobu reaction.

Pb-Zr mixed oxides with 15.2 wt% PbO loading were prepared by four different preparation processes, and their catalytic performances for the disproportionation of methyl phenyl carbonate (MPC) to synthesize diphenyl carbonate (DPC) were evaluated. Physicochemical characterizations including X-ra...

When working on design of intensified processes or develop of a new technology it is very important to have the necessary tools and criteria to select the best option. In this work the environmental impact and occupational health of twelve intensified reactive distillations processes to produce ...

The solid–liquid equilibrium (SLE) data for five binary systems containing diphenyl carbonate (DPC), i.e., ethanol, 1-propanol, 2-propanol, diethyl carbonate, or dipropyl carbonate + DPC, were determined experimentally. We designed a new experimental apparatus based on a synthetic method for th...

Sprague-Dawley rats were administered ethylenethiourea (ETU), 1,3-dimethyl-2-thiourea (DMT), 1,3-dibutyl-2-thiourea (DBT), or 1,3-diphenyl-2-thiourea (DPT) by gavage from Days 6 to 20 of gestation. Daily dosage levels (mg/kg/day) were ETU at 0, 15, 25, and 35; DMT at 0, 15, 25, 50, 100, and 200;...

An efficient and direct procedure for the synthesis of 4,6-diphenyl-3,4-dihydropyrimidine-2(1H)-thione derivatives by condensation of 1,3-diaryl-2-propen-1-ones (chalcones) and thiourea in ethanol at 65 °C using triphenylphosphine (PPh3) as a catalyst is reported. The method gave good yields of...

The reaction of P4S10 (1) with N,N′-diphenylurea (PhNH)2CO (2) results in new heterocyclic compounds: the pyridinium salt of 1,3-diphenyl-2-sulfido-2-thioxo-1,3-diaza-2λ5-phosphetidine (3) (with a P–N–C–N cycle) and the pyridinium salt of 1,4-diphenyl-2,5-disulfido-2,5-dithioxo-1,4-dithiadi...

N-[Chloro(dimethyl)silyl]methyl-N,N′-diphenylurea with intramolecular coordination bond C=O→Si was prepared by interaction of N,N′-diphenylurea with silane ClCH2SiMe2Cl. Structure of this compound was confirmed by 1H, 13C, 29Si NMR spectroscopy and X-ray diffraction analysis.