Poly(isobutyl cyanoacrylate) nanoparticles were prepared. They were degraded in two enzyme-free media at pH 7 and 12 in the presence of rat liver microsomes.The conventional formaldehyde-producing degradation route was studied, and showed a very low efficiency. Another pathway, consisting of est...

Knöevenagel reactions of aldehydes and ketones with malononitrile, isopropyl cyanoacetate and diisopropyl malonate catalyzed by Ti(O-i-Pr)4 proceeded smoothly in i-PrOH to give the corresponding reaction products in good to high yield. 3-Substituted coumarins were prepared by the present method.

A novel method for the preparation of alkyl azides from alcohols by way of oxidation–reduction condensation is described. In this reaction, the sterically-hindered tert-alkyl phosphinites that are prepared from the corresponding alcohols are converted into tert-alkyl azides with almost complete...

Methyl and i-propyl radicals have been found to react with methyl diphenylphosphinite to give respectively, methyldiphenylphosphine oxide and i-propyldiphenylphosphine oxide. t-Butyl radicals under similar conditions, initiated the transformation of the ester to methyldiphenylphosphine oxide. Be...

In this article, 2-aminophenyl diphenylphosphinite has been introduced as a new ligand for the Heck–Mizoroki reactions of aryl halides with styrene and n-butylacrylate in water in the presence of palladium acetate. This ligand is easily prepared from the reaction of chlorodiphenyl phosphine wit...

An efficient heterogeneous copper-free Sonogashira–Hagihara coupling reaction was performed in the presence of 2-aminophenyl diphenylphosphinite (L) as a ligand, Pd(OAc)2 and a base in neat water at 25–95 °C. By this protocol, different aryl halides (Cl, Br, I) were reacted with phenylacetyle...

A series of para-substituted phenyl diphenylphosphinites [Ph2POPh-p-R, where RH (1), CH3 (2), tBu (3) and Cl (4)] were prepared in near quantitative yields, by the reaction between the desired para-substituted phenol and chlorodiphenylphosphine, in the presence of triethylamine. The electrochemi...

Secondary Ion Mass Spectrometry (SIMS) has been used to study the surfaces of natural galena (lead sulfide) crystals treated with a homologous series of dialkyl dithiophosphinates. The semiquantitative adsorption data, as a function of pH, obtained from the near static SIMS measurements using th...

The beneficial effects of the synergy between two or more reagents were realized long time ago. The purpose of using a mixture of collectors was to increase both the recovery and selectivity. In this work, two thiol collectors, isopropyl xanthate (SIPX) and di-isobutyl dithiophosphinate (DTPI), ...

The interaction of sodium-di-isobutyl dithiophosphinate (DTPINa) with galena and pyrite in alkaline media (pH 9) was examined using cyclic voltammetry, open circuit potential and contact angle techniques. Analysis of results suggests that the collector interacts with the minerals by chemical and...

1. 2-Methyl-1,4-benzoquinone (MBQ), 2-ethyl-1,4-benzoquinone (EBQ) and 1-pentadecene (PD) were identified in Tribolium madens and T. brevicornis by gas-liquid chromatography.2. MBQ, EBQ and PD were extremely low in newly eclosed adults (

1.1. 2-Methyl-1,4-benzoquinone (MBQ), 2-ethyl-1,4-benzoquinone (EBQ) and 1-pentadecene (PD) concentrations in Tribolium confusum and T. castaneum were found to be extremely low in newly eclosed adults (

1-Alkenes are traditionally used as basic chemicals with great importance. Biosynthetic 1-alkenes also have the potential to serve as biofuels. In this study, we engineered a Pseudomonas lipolytic microbial platform for 1-alkene production using hydrophobic substrate as sole carbon source. Fatty...

The removal of low concentration of chlorbromuron herbicide in aqueous systems was carried out by electro-Fenton process comprised of three-electrode divided and undivided cell with a reticulated vitreous carbon cathode and platinum anode. The electro-Fenton was also carried out in a two-electro...

Dispiro derivative of 7-oxa-1-azabicyclo [2.2.1]heptane 5 was synthesized as a single stereoisomer from N-(5-allyl-spiro [1,3-dioxan-2,1′-cyclohexane]-5-yl)hydroxylamine 2 and protected d-mannose 3, through intramolecular 1,3-dipolar cycloaddition of in situ formed N-(but-3-en-1-yl)nitrone 4. S...

The reaction of cesium fluoride with the 2-acyloxy 3-chloro 2-chloromethylpropanamides (4) gave the 3-acyloxy 3-chloromethyl azetidine 2-ones (6) . Treated by powdered potassium hydroxide, 4 and 6 were converted into the 1-oxa 4-oxo 5-aza spiro (2,3) hexanes. These reactions in heterogeneous med...

Reactions of pyruvic acid hydrazone series [pyruvic acid thiophenecarbonyl hydrazone (L1), pyruvic acid 4-hydroxybenzoylhydrazone (L2), pyruvic acid salicyloylhydrazone (L3), pyruvic acid benzoylhydrazone (L4)], or salicylaldehyde hydrazone Schiff base ligand [salicylaldehyde isonicotinoylhydraz...

Conjugated microporous polymers (CMPs) with permanent microporosity and extended p-conjugated skeletons have recently shown the fascinating application in separation and enrichment. In this report, porphyrin CMP that possessed microporous structure and nitrogen-rich pyrrole building blocks was s...

CYP17A1-independent intratumoral steroid hormone synthesis is regarded as one possible explanation for resistance to treatment with the CYP17-inhibitor Abiraterone (Abi). The aim of our study was therefore to investigate the steroid metabolism of prostate cancer cells under serum starvation and ...

The urgent need in search of new biological entities to fight back with recent drug-resistant microbial flora, has led us report a library of s-triazine derivatives. The intermediate 4-((4-chloro-6-methoxy-1,3,5-triazin-2-yl)amino)benzonitrile 3 was substituted with various thiophenol, phenol, a...