A series of 2-amino-4-(4-methylpiperazin-1-yl)-1,3,5-triazines was designed based on previously published 2-amino-4-benzyl-(4-methylpiperazin-1-yl)-1,3,5-triazines in order to evaluate the role of a linker between the triazine moiety and an aromatic substituent for the human serotonin 5-HT6 rece...

The initial reaction of silicon precursors with a varying number of dimethylamino (N(CH3)2) ligands on a hydroxyl-terminated silicon (0 0 1) surface was investigated using density functional theory. Five silicon precursors were chosen to evaluate their adsorption energy and reaction energy barri...

A detailed analysis of monodentate and bidentate complexation of tris(pentafluorophenyl)silyl (TPFS) derivatives with neutral Lewis bases was performed. The NMR spectroscopy and X-ray diffraction analysis (11 structures) were the key methods to characterize tetra- or pentacoordinate silicon comp...

ObjectivesThe purpose of this study was to evaluate the polymerization behavior of a model dentin adhesive with tris(trimethylsilyl)silane (TTMSS) as a co-initiator, and to investigate the polymerization kinetics and mechanical properties of copolymers in dry and wet conditions.

Silicon nitride (SiNx) films were prepared using an organosilicon monomer, Trisdimethyl-aminosilane ((Me2N)3SiH: TDMAS) by a remote plasma CVD. Plasma was generated by a mixture of hydrogen and nitrogen gases while the monomer was introduced into the downstream. Deposition of SiNx films were ini...

Atomic layer deposition of SiO2 from tris(dimethylamino)silane (TDMAS) and ozone as precursors on Si(100) surfaces at near-room temperatures was studied by infrared absorption spectroscopy with a multiple internal reflection geometry. TDMAS can be adsorbed at OH sites on hydroxylated Si surfaces...

Non-heating atomic layer deposition of SiO2 is developed using tris(dimethylamino)silane (TDMAS) and plasma-excited water vapor. The plasma-excited water is effective in oxidizing the TDMAS-adsorbed SiO2 surface while leaving OH sites on the growing surface at room temperature for further TDMAS ...

The majority of eukaryotic regulated protein turnover is performed by the proteasome, a multi-catalytic enzyme. Due to the fact that proteasome enzyme abnormal functioning was observed in different malignant cells, the proteasome is becoming a target for medical treatment. In order to evaluate t...

Multiple complexes of 20S proteasomes with accessory factors play an essential role in proteolysis in eukaryotic cells. In this report, several forms of 20S proteasomes from extracts of Spodoptera frugiperda (Sf9) cells were separated using electrophoresis in a native polyacrylamide gel and exam...

A novel bio-based main chain benzoxazine with two oxazine rings and one phenolic hydroxyl group in the same aromatic ring was synthesized and characterized. The method includes the synthesis of polymeric benzoxazine precursors from simple chemicals such as gallic acid, gallic amide, 4,7,10-triox...

Two series of aromatic poly(amide-benzoxazole)s have been obtained from 5-chlorocarbonyl-2-(4-chlorocarbonylphenyl)benzoxazole (NBOC) and 6-chlorocarbonyl-2-(4-chlorocarbonylphenyl)benzoxazole (OBOC). NBOC and OBOC were synthesized by a three-step process with high yields, and they were reacted ...

The reaction of silyl iodide with phosphorus, phosphine, arsenic and the arsenides of potassium and mercury has been studied. The compounds P(SiH3)I2 and As(SiH3)I2 have been isolated and characterized. Both decompose below 100°. Evidence is presented for the existence of the compounds P(SiH3)2...

An intuitive approach to differentially all-carbon tetrasubstituted olefins from a scaffold of (E)-1-bromo-2-iodoalkenes is described. The iodine atom of the scaffold selectively undertook CuTC-mediated cross-coupling reactions with organotin reagents, suppressing a side-reaction of β-halogen e...

Some new 1,3,5-substituted-2,3-dihydro-2-imino-benzimidazoles were synthesized under solid–liquid phase transfer catalysis conditions using 5-substituted-2-aminobenzimidazoles as precursors in order to assess their cytotoxicity respectively proliferative activity. The structures of the compound...

The experimental FT-IR and FT-Raman spectra of 4 – [(3, 4 –dichlorophenyl) amino] 2 – methylidene 4 – oxo butanoic acid (DMOA) has been recorded. Quantum chemical calculations of geometry and vibrational wavenumbers of the title compound are carried out theoretically and were compared with t...

Rifamycin SV (rifamycin), is a member of the ansamycin family of antimicrobial compounds which kills bacteria commonly associated with infectious diarrhea and other enteric infections. Rifamycin has been found to be effective in experimental animal models of gut inflammation and its efficacy in ...

The autoxidation of fatty acid methyl esters (FAMEs) derived from colza, sunflower, linseed and tung oils and the oxidation of sunflower FAMEs in the presence of several commercial driers based on Co(II), Mn(II), Fe(II), V(IV), Sr(II), Zr(IV), Ca(II), Zn(II) have been investigated. The oxidation...

A new P-chiral phosphine ligand with a 1,2-phenylene unit, (S,S)-1,2-bis(isopropylmethylphosphino)benzene, has been synthesized from 1,2-bis(methylphosphino)benzene. Its rhodium complex is highly effective in asymmetric hydrogenation of dehydroamino acid methyl esters to provide enantioselectivi...

Ketenes are mostly used as the remarkable and common starting materials for structurally diverse five-membered and fused five-membered compounds, such as lactones, furans, benzofurans, dioxolane derivatives, pyrroles, succinimide, indoles, oxindoles, isoindoles, thiophenes, oxazoles, benzoxazole...

Mannich base derivatives 1–3 were biotransformed through tandem enzymatic reactions by using several microorganisms isolated from Brazilian biomes. The hydrochlorides 1 and 3 produced propiophenone 1a, α,β-unsatured ketone 2c and alcohol (S)-1b (yield 40%, e.e. 81%, Aspergillus terreus). The ...