2-[2-(Acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) and 4-amino-3,3′-dichloro-5,4′-dinitrobiphenyl (ADDB) are two compounds, which show strong mutagenicity toward bacteria, that have been identified as major mutagens in river wate...

We have previously isolated five mutagens in blue rayon-adsorbed substances from water at a site below sewage plants in the Nishitakase River, in Kyoto, Japan, and identified two of them as 2-phenylbenzotriazole derivatives, 2-[2-(acetylamino)-4-[bis(2-methoxyethyl)amino]-5-methoxyphenyl]-5-amin...

In this study, the synthesis of novel Monostyryl and Distyryl boron dipyrromethene dyes containing 4-((2-hydroxyethyl)(methyl)amino) group to determine neuroprotective potential has been reported for the first time. They were synthesized starting from BODIPY dye 1. Their inhibitory properties ag...

Solution-processable hole transporting materials (HTMs) play a vital role in organic light emitting diodes (OLEDs) with the purpose of reducing costs and improving productivity. Herein, two twisted HTMs N2,N2,N7,N7-tetrakis(4-(3,6-di-tert-butyl-9H- carbazol-9-yl)phenyl)-9,9-dimethyl-9H-fluoren-2...

Seven salts were formed with phenylacetic acid (PAA), 4-hydroxyphenylacetic acid (HPAA) and the Cinchona alkaloids; cinchonidine (CIND), quinidine (QUID) and quinine (QUIN). For all the structures the proton was transferred from the carboxylic acid of the PAA/HPAA to the quinuclidine nitrogen of...

Various diclofenac acid hydrazones and amides were synthesized and evaluated for in vitro and in vivo antimycobacterial activities against Mycobacterium tuberculosis. Preliminary results indicated that most of the compounds demonstrated better in vitro antimycobacterial activity (MIC: 0.0383–7....

The [email protected] was used as a new catalyst for synthesizing 7H-indeno[2,1-c]quinoline derivatives. The catalyst was integrated according to three-step synthesis. Zn-Cr layered double hydroxides (LDHs) were synthesized with molar ratio 2:1 by the co-precipitation method.

A new quinoline-2-carboxylic acid, 4-hydroxy-6-methoxyquinoline-2-carboxylic acid (6-methoxy-kynurenic acid), has been isolated from Ephedra pachyclada ssp. sinaica. Kynurenic and 6-hydroxykynurenic acids, previously reported from plants, were also isolated from Ephedra.

Multiparallel amenable syntheses of 6-methoxy-8-amino-4-oxo-1,4-dihydroquinoline-2-carboxylic acid-(4-morpholin-4-yl-phenyl)amides (I) and 4-amino-6-methoxy-8-(4-methyl-piperazin-1-yl)-quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides (II) which facilitate late-stage diversification at...

The synthesis and antiproliferative effect of a series of quinoline and thiazole containing coumarin analogs 12a-d and 13a-f respectively, on mice leukemic cells was performed. The chemical structures of newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR and mass spectral analysis...

1.(1) Dibucaine evokes a downward shift shift in the phase transition temperature of saturated phosphatidylcholines, while it also affects the pretransition.2.(2) The binding of dibucaine to phosphatidylcholine liposomes increases sharply when the lipid is transformed from the gel phase to the l...

Binding of micromolar concentrations of the local anesthetic dibucaine to micelles of cationic, zwitterionic and anionic detergents was studied using the fluorescence emission of dibucaine. Difference in quantum yields for charged and neutral dibucaine allowed to obtain shifts of pKa values due ...

Publisher SummaryDibucaine is 2-butoxy-N-[2-(diethylamino)­ethyl]-4-quinolinecarboxamide. This chapter discusses the physical and chemical properties, synthesis, stability-degradation, drug metabolism and pharmacokinetics, toxicity, and methods of the analysis of dibucaine. The proton nuclear ma...

SummaryIn an extension of our work in the field of nitrogen heterocycles with potential cytotoxic activity, the synthesis of some substituted 4-chloro-3-(2-chloroethyl)-2-methylquinolines (10–13) from their parent 3-[1-(phenylamino)ethylioene]-dihybro-2(3H)-furanomes (6–9) is reported. The con...

Secondary organic stabilizers are known to give synergistic effects with metal soap stabilizers in the thermal stabilization of poly(vinylchloride) PVC. In this study, it is shown that some of them are also good costabilizers with dioctyltin thioglycolate (DOTTG). Epoxidized soyabean oil (ESO), ...

We conducted a study on the transport properties of an ionic liquid 4-(2-methoxyethyl)-4-methylmorpholin-4-ium bis(trifluoromethylsulfonyl)amide ([MorMEOM][TFSI]) and lithium bis(trifluoromethanesulfonyl) imide (LiTFSI)-doped [MorMEOM][TFSI] at various temperature and atmospheric pressure states...

A new 1-(4-Nitrophenyl) pyrrolidine single crystal has grown by slow evaporation solution growth technique. The grown crystal have characterized by single crystal X-ray analysis, and it shows that 1-(4-Nitrophenyl) pyrrolidine crystallizes in the orthorhombic space group Pbca, with cell paramete...

A methodology based on optical fibre (OF) detection was developed for screening the potential of CLA production by Lactobacillus casei-01, Lactobacillus acidophilus La-5 and Bifidobacterium lactis B94 in probiotic curdled milk. The OF based methodology was validated by comparison with an analyti...

The complementary blending of tung oil biodiesel with coconut oil and palm kernel oil biodiesels was investigated to improve the biodiesel properties. Tung oil is considered a potential non-edible oil feedstock for biodiesel production. However, tung oil biodiesel has unfavorable fuel properties...

The Schinziophyton rautanenii tree is an important food source for many communities of the African continent. Oil extracted from the Manketti nut is of great economic value, due to its unique composition and properties. In this study, the physical and chemical characteristics of the oil obtained...