T-2 toxin is a secondary metabolite produced by Fusarium genus and is a common contaminant in food and feedstuffs of cereal origin. In porcine granulosa cells(GC), T-2 toxin has been shown to inhibit the steroidogenesis; however, the mechanism has not been well understood. Gonadotropin-stimulate...

T-2 toxin is the most toxic member of trichothecene mycotoxin. So far, the mechanism of mitochondrial toxicity and protective mechanism in mammalian cells against T-2 toxin are not fully understood. In this study, we aimed to investigate the cellular and mitochondrial toxicity of T-2 toxin, and ...

T-2 toxin is a highly toxic mycotoxin produced by various Fusarium species, mainly, Fusarium sporotrichoides, and has been reported to have toxic effects on reproductive system of adult male animals. This study investigated the dose-dependent cytotoxicity of T-2 toxin on reproductive cells using...

Procyanidins B2 (PB2) was found to block T-2 toxin-induced reproductive toxicity and may be used as a dietary preventive agent. We investigated the mechanism of PB2 in blocking the T-2 toxin-induced apoptosis in Leydig cells in conjunction with analysis of T-2 toxin induced proapoptotic response...

Herein, fine powders of yellow pigments based on BiVO4 were successfully prepared in two crystalline forms, tetragonal zircon-structured and monoclinic scheelite-structured, through a ethylene glycol-assisted method subjected to a thermal treatment at two different temperatures. The obtained mat...

There are limited studies on the tribological properties of SiAlON-TiN composites. Therefore, in the present study, tribology tests were conducted on a number of αı/βı-SiAlON-TiN composites with different αı/βı-SiAlON phase ratio and TiN content, fabricated with unique compositional design. ...

Herein, SiC films were prepared by DC pulse magnetron sputtering on ceramic substrates using SiAlON as buffer layer. The influence of SiAlON buffer layer thickness on the structural, morphological, and mechanical properties of the SiC/SiAlON bilayers was discussed. The result show that SiAlON bu...

β-Sialon bonded Al2O3–C refractories possess high strength and superior thermal shock performance. In this study, the growth of preferred β-Sialon (Si3Al3O3N5) and its effects on thermo-mechanical properties of Al2O3–C refractories were investigated via simulations and experiments. The resul...

Two different types of SiAlON phosphors, namely, α-SiAlON:Eu and β-SiAlON:Eu, that have been developed as scintillators are evaluated for their luminescent properties by ion-beam-induced luminescence (IBIL) analysis under 2–3-MeV H+-microbeam irradiation. The IBIL spectra show that both α-Si...

Ca-α-SiAlON powder was prepared by carbothermal reduction nitridation process at nitrogen atmosphere without using high pressure and long holding time. The precursor was prepared by a novel colloidal sol-gel process consisting of silica, alumina, calcium oxide and carbon. The obtained powders w...

Ca-α-SiAlON ceramics with high porosity and fine rod-like grains were fabricated using unidirectional freezing and pressureless sintering. The high porosity of green body was maintained during sintering, which was mainly controlled by solid loading of slurry. Phase analysis showed that α-SiAlO...

Porous SiAlON ceramics were produced by incorporating starch in the range of 0–5 wt% in a commercial grade SYALON 101 powder and pressureless sintered at 1700 °C for 4 h in nitrogen atmosphere. The crystal phase formation, microstructure, dielectric- and mechanical properties of SiAlON ceramic...

Columnar β-Sialon bonding phases were in situ synthesised in Al2O3-C refractory composites and their growth mechanism was simulated based on first-principles calculations. The experimental results indicated that the addition of Fe2O3 as a catalyst accelerated the transformation of Si3N4 to β-S...

Ca-α-SiAlON powder was synthesized by carbothermal reduction nitridation process at a low temperature (i.e., 1400 °C, 2 h). The precursor was prepared by a novel sol-gel process. The effect of carbon content and seeding on the microstructure and purity of the Ca-α-SiAlON powder was investigat...

When used as implants, Al2O3 is unable of directly achieving good chemical bonding with soft and hard tissues. To overcome this problem, SiAlON–Al2O3 ceramics were prepared in this study by direct nitridation. Phase composition, porosity, bulk density, and compression strengths were examined, a...

FT Raman and IR spectra of the crystallized biologically active molecule, 5-Amino-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (5-APHC, C11H11N3O) have been recorded and analyzed. The equilibrium geometry, bonding features and harmonic vibrational frequencies of 5-APHC have been investigated wit...

The synthesis and structure–activity relationships of a series of simple biphenyls is described. Optimization of the 4-hydroxy-biphenyl template led to compounds with ERβ selectivity on the order of 20–70-fold.

Background/aimsPyrimidines have a long and distinguished history extending from the days of their discovery as important constituents of nucleic acids to their current use in medicinal chemistry. As a part of project devoted to the development of pyrimidine analogs as antimicrobial agents we hav...

A peptide with neurokinin A-like immunoreactivity was isolated from an extract of the intestine of an elasmobranch fish, Torpedo marmorata. The primary structure of the peptide was established as Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2. This amino acid sequence is ide...

A preparative high-speed counter-current chromatography (HSCCC) with a two-phase solvent system composed of ethyl acetate–n-butanol–water (2:7:9, v/v/v) was successfully performed to isolate and separate clemastanin B and indigoticoside A from the plant of Radix Isatidis, a traditional Chinese...