Tin mesoporphyrin (SnMP), a competitive heme oxygenase (HO) inhibitor, also induces HO-1 mRNA and protein expression by a mechanism that is not fully understood. We examined whether the induction by SnMP is mediated by a de-repression of Bach1, a transcription factor that suppresses the HO-1 gen...

Ternary nanocomposites were fabricated based on an optimized impact modified polyamide-6 (PA-6)/low density polyethylene grafted maleic anhydride (LDPE-g-MA) blend composition with varied concentration (∼0–6 wt.%) of organoclay, Cloisite 30B™. The microstructural attributes such as state of in...

Low dielectric constant (low-k) porous films of high density polyethylene-grafted-maleic anhydride were prepared via thermally induced phase separation (TIPS) using di-n-octyl phthalate as the solvent and methanol as the extractant. The results show that, for the process of TIPS, cellular struct...

Three polyethylenes (HDPE, LDPE and LLDPE) have been irradiated with UV light, as a pre-step for hydroperoxide production, before a bulk grafting reaction with maleic anhydride (MAH). The method was compared with a traditional grafting procedure using peroxides. The grafting reaction was followe...

The effect of a nitroxyl-based radical scavenger (tretramethyl piperidino radicals, TEMPO or indolynoxyl radicals, DPAIO) on the course of the melt radical grafting of maleic anhydride (MA) onto polyethylene has been explored. The reaction was conducted at 160 °C in a mini-extruder with 2,5-dim...

Engineering thermoplastics with cellulosic fibers are in the focus because of the higher strength and heat deflection temperature but processing is still challenging. Therefore, in this investigation polybutylenterephthalat (PBT) and bio-based polytrimethylentherephthalat (PTT) was used as a pol...

This paper presents a comparative study of the use of polyethylene grafted maleic anhydride (PE-g-MAH) and glut palmitate salt (GP) as compatibilizers in silica-filled high-density polyethylene (HDPE) composites. The composites with varied compatibilizer loadings [0.5–3.0 phr] were prepared by ...

Polymer layered silicate nanocomposites are very prevailing in both basic research and industrial development, among them montmorillonite (MMT) provide the most significant applied value. In this study, structures and properties of various organic/inorganic nanocomposites of low-density polyethy...

Novel films of polyethylene and chitosan were obtained using extrusion. These polymers have interesting properties, and processing them with methods that are of high use in the industry, such as the extrusion method, can have a significant effect on the potential applications of these materials....

Cassava starch was melt-blended with glycerol (70/30 wt%/wt%) at 140 °C to prepare thermoplastic starch (TPS). Chitosan (CTS) was premixed with starch and glycerol, in acidified water (lactic acid 2 wt%), at 1, 5 and 10 wt%/wt%. TPS/CTS was then melt-blended (160 °C) with polyethylene-graft-ma...

Pharmacological studies on bis-(2-methyl-2-nitropropyl) sulfite indicate that this compound has sedative, hypotensive, and antispasmodic activity. The drug also possesses a negative chronotropic and negative inotropic action upon the frog heart. The results of a chronic toxicity study are also r...

Granular 2-nitropropyl potato starch was synthesized by reaction with 2-nitropropyl acetate in an aqueous suspension. Nitroalkylation occurs preferentially with the amylose fraction of potato starch, as was confirmed by leaching experiments and digestion of the modified starch with α-amylase. T...

A number of azomustard derivatives have been shown by t.l.c. to consist of two components. In the case of CB 10-252, 4-[bis-(2-bromopropyl)amino]-2'-carboxy-2-methylazobenzene, these have been separated by preparative h.p.l.c. They are apparently diastereoisomers, chloroform solutions of wh...

Here we report on the charge partition between c and z fragments formed after femtosecond collisional electron-transfer from Cs atoms to charge-tagged peptide dications. Peptides chosen for study were Ala-Lys (AK) and Lys-Lys (KK) where one or both of the lysine ε-amino groups were trimethylate...

The global problem of advancing bacterial resistance to newer drugs has led to renewed interest in the use of Chloramphenicol Palmitate (C27H42Cl2N2O6) [Palmitic acid alpha ester with d-threo-(-),2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide also known as Detereopal...

A pharmaceutical active compound, chloramphenicol palmitate, appears in three polymorphic forms, that can be observed at room temperature. The stable form A (biologically inactive modification), the meta-stable form B (active modification) and unstable form C were found to have distinct Raman sp...

(±)-Chloramphenicol palmitate has been efficiently resolved by enantioselective hydrolysis in organic medium in the presence of Rhizopus sp. lipase affording the palmitate of RR-chloramphenicol and SS- chloramphenicol in high chemical and enantiomeric yields.

The stereo- and enantioselective synthesis of the yellow scale pheromone, (S)-(-)-3,9-dimethyl 6-(1-methylethyl) (E)-5,8-decadien 1-ol acetate, from 3-(R)(̃+)-valerolactone 5 and [(4-methyl 3-pentenyl) sulfonyl] benzene 8 is described. The key step is the introduction of the isopropyl group by t...

A Ni-catalyzed addition of arylboronic acids to isatins was first developed. The reaction, driven by Ni(acac)2 and dppp as the phosphine ligand, gave 3-aryl-3-hydroxy-2-oxindoles in up to 97% yield. Scopes of benzyl-protected isatins and arylboronic acids were examined. Substituted phenylboronic...

Betulinic acid (BA), a pentacyclic triterpenoid, exhibits broad spectrum antiproliferative activity, but generally with only modest potency. To improve BA’s pharmacological properties, fluorine was introduced as a single atom at C-2, creating two diastereomers, or in a trifluoromethyl group at ...