Compared with humic acids or proteins, polysaccharides usually cause more severe flux decline. Here, the ultrafiltration (UF) membrane fouling caused by alginate coagulated with iron (III)/alum salt was investigated in the absence/presence of ionic strength (NaCl), calcium ions and their combina...

Stripping is a necessary step for the recovery and reuse of extracting agent in hydro metallurgical process. This study reported an effective way employing sodium sulfite for the stripping of iron(III) from Aliquat 336 with a high iron loading, which was generated in the iron removal from coal w...

The synthesis of a tetra β(1→5) galactofuranoside was achieved using a thioglycoside donor with a methyl tert-butyl phenyl thio leaving group. This tetrasaccharide was conjugated to biotin and validated as antigen with the monoclonal antibody used for clinical detection of Aspergillus fumigatu...

A series of new 2-[1,8]naphthyridinyl and bis(2-[1,8]naphthyridinyl) bridging ligands with multidentate binding sites were prepared using 2-amino-5-cyano-6-ethoxy-4-phenyl-3-carbaldehyde pyridine as excellent Friedländer synthon. Condensation with a series of acetyl(heteroaryl)aromatics provides...

A kinetic study has been made of the three dimensional polymerization of a system including copolymer of tetrahydrofuran and propylene oxide, 1,1,1-trimethylolpropane and 2,2-bis-(4-isocyanatophenyl)hexafluoropropane in the temperature interval 27–80°. The effect of polymerization temperature ...

New organic non-centrosymmetric Schiff base material 4-Nitro-benzoic acid (3-ethoxy-2-hydroxy-benzylidene)-hydrazide was synthesized and grown as single crystal by slow evaporation solution growth technique. Single crystal X-ray diffraction reveals the noncentrosymmetric nature of the grown crys...

Intra-molecularly hydrogen bonded compound 2-(1,4-dioxo-1,4-dihydronaphthalen-2-yl-amino)benzoic acid (ANQ) shows emission at single wavelength upon excitation in UV-region whereas it shows dual fluorescence emissions on excitation in visible region. Such emissions depend on solvent, concentrati...

A series of 1,2,4-triazole derivatives (1–17) was synthesized and evaluated for its antimicrobial and anticancer potentials. Antimicrobial screening of the synthesized compounds indicated that they were most potent against Aspergillus niger and compound 14 was found to be the most active. Compo...

The disaccharides related to glycosyl phosphatidyl Inosltol anchors of membrane proteins, 4-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol-1-phosphate and 4-O-(2amino-2-deoxy-α-D-galactopyranosyl)-D-chiro-inositol-1-phosphate, have been prepared from optically resolved myo-inosltol deri...

Using a combination of high-performance ion chromatography analysis and kinetic studies, the stereospecificity of myo-inositol hexakisphosphate dephosphorylation by the phytate-degrading enzyme P2 of Escherichia coli was established. High-performance ion chromatography revealed that the phytate-...

1,2,3,4-Tetrahydroisoquinoline (TIQ) and some of its derivatives, such as 1-benzyl-TIQ and 1-methyl-TIQ, are endogenously present in human brain and are thought to contribute to induction or prevention of Parkinson’s disease. In the present study, we estimated the effects of the artificially sy...

1-Methyl-4-cyclohexyl-1,2,3,6-tetrahydropyridine (MCTP), an analog of MPTP, was found to be an MPTP-like neurotoxin. MCTP administration caused extensive losses of neostriatal dopamine and its major metabolites in male Swiss-Webster mice. Under similar experimental conditions, MCTP was approxima...

The O-acetyl, propionyl, butyryl and pivaloyl esters of timolol were synthesized and evaluated as prodrugs for potential in diminishing the systemic absorption and therefore side effects of topically applied timolol through increased corneal permeation. The esters showed a 14–525-fold increase ...

Some lower aliphatic esters of timolol have previously been developed as prodrugs to potentially diminish the systemic absorption and hence side-effects of topically applied timolol through increased corneal absorption. Although these esters are promising timolol prodrugs for ocular delivery, th...

The effectiveness of the prodrug approach in maximizing the ratio of ocular to systemic absorption of topically applied timolol was compared with that based on viscous solutions. The pigmented rabbit was the experimental animal. o-Butyryl timolol, a lipophilic ester prodrug of timolol, was found...

Rationale and Objectives.We studied the intestinal absorption of manganese mesoporphyrin (Mn-mesoporphyrin), a potential oral hepatobiliary contrast agent.

Background & AimsThe nonstructural 5A (NS5A) protein of hepatitis C virus (HCV) plays a critical role in HCV replication and is an attractive target for the therapy of HCV infection. So far, little is known about the posttranslational regulation of NS5A protein and its precise role in HCV RNA re...

In this work we investigate both the stationary and transient spectroscopic properties of mesoporphyrin IX when incorporated into porous matrices produced using the sol–gel technique. These matrices were produced using both titanium and silicon containing precursors to form solid glassy monolit...

H2-mesoporphyrin IX and Zn-mesoporphyrin IX have been investigated as sensitizers for the titanium dioxide (TiO2) film electrode to construct a new two-compartment photoelectrochemical biofuel cell (PEBFC). The PEBFC can convert the light and chemical energy to electricity by consuming photons a...

The absorption and fluorescence characteristics of tin(IV) mesoporphyrin (SnMP) and its analog tin(IV) protoporphyrin (SnPP) were studied in a series of organic solvents. Fluorescence quantum yields were calculated using the Strickler–Berg equation. Good correlation was found between calculated...