BackgroundPilsicainide hydrochloride is a class IC antiarrhythmic agent used for the treatment of supraventricular and ventricular arrhythmias and atrial fibrillation.

In our previous study, we demonstrated that folate-appended methyl‑β‑cyclodextrin (FA-M-β-CyD) was a promising antitumor agent for the treatment of folate receptor-α (FR-α)-expressing tumors. In the present study, to enhance the antitumor effect of FA-M-β-CyD against FR-α- and CD44-express...

Zr:W:Si. The optimum gel was prepared using the molar ratio 1:1:7 at pH 8. The ZrSiW gel was investigated by FTIR, XRD, thermal analysis (TGA and DTA), FESEM, XRF, and NAA. Then, XRF and NAA techniques were used to estimate the proportion of the constituents of the gel according to the molecular...

Zirconium tungstate Zr(WO4)2 exhibits irreversible amorphization at high pressure. Upon heating, the pressure-amorphized phase transforms into different phase/phases depending on the pressure applied during heating. Transformation of pressure-amorphized samples to metastable cubic phase during i...

This composite was prepared from zirconium tungstate Zr(WO4)2 and graphene oxide (GO) by in-situ chemical reduction of a mixture containing GO and Zr(WO4)2. The morphology and structure of the composite were confirmed by various physicochemical techniques. The materials was used in a tyrosinase-...

The formation of zirconium tungstate hydroxide hydrate, a precursor to the negative thermal expansion material cubic zirconium tungstate, shows a strong dependence on hydrothermal reaction conditions. It was found that not only the acid concentration, but also the acid counterion plays a signifi...

This article discusses some peculiarities of the synthesis of ZrW2O8 (1) using thermal decomposition of the precursor ZrW2O7((OH)1.5,Cl0.5)·2H2O (2) prepared by hydrothermal method. On hydrothermal synthesis of 2 the optimal concentration of hydrochloric acid in the reaction mixture is about 2....

Proton conducting polymer electrolyte membrane is the most important component of polymer electrolyte membrane fuel cells (PEMFC). The positive effect of addition of oxo-clusters of Ti, Zr, W and hydrophilic additives like SiO2, TiO2 and ZrO2 on the proton conductivity characteristics of Nafion ...

It is necessary to synthesize new material for the advancements of the technology. In this study, new and novel poly(2-anisidine)@zirconium tungstate (P2A/ZrW2O8) was synthesized by simple so-gel method. Physicochemical characterization of P2A/ZrW2O8 was done by thermogravimetric analysis (TGA),...

Thermal cracking is a widespread distress for asphalt pavement in cold regions. The main reason causing thermal cracking is due to the contraction of asphalt concrete. Once thermally induced contraction stress exceeds the fracture resistance of the asphalt concrete, cracks start to develop. Comp...

Amorphous zirconium tungstate (a-ZrW2O8), prepared at 7.7 GPa, was subjected to successive heat treatments at increasingly higher temperatures, up to 640 °C. Evidence of recrystallization into α-ZrW2O8 was found in the room temperature X-ray powder diffraction pattern of samples previously hea...

In this study nanoclusters of zirconium tungstate (ZrW) were synthesized hydrothermally in a stainless steel autoclave and its bionanocomposite with chitosan (CZrW) was fabricated. The synthesized ZrW and CZrW were characterized by UV, FTIR, XRD, TEM Raman and TGA techniques and further explored...

Friedel-Crafts acylations of 3-alkyl-1-(phenylsulfonyl)pyrroles appear to be kinetically favored at the adjacent C-2 position but rearrangement to the C-5 position can occur after prolonged reaction times. This reversible Friedel-Crafts methodology has been employed for the synthesis of the ant ...

The conjugated bis(sulfonyl)nitrobutadienes 1 undergo, with primary amines, competitive MeSO2 replacement [vinylic substitution at C(1)] versus aza-Michael addition to the nitroethenyl C(3)–C(4) double bond. The latter pathway eventually leads to the trisubstituted pyrroles 2 and conditions hav...

p-Toluenesulfonyl isocyanate (PTSI) is introduced as electrolyte additive in a bid to enhance the electrochemical performances of LiNi0.5Co0.2Mn0.3O2 cathode materials under high voltage. A less resistive and stable film on the cathode surface derived from PTSI oxidation which taken place prior ...

Organic sulfonyl fluorides are of interest owing to their insecticidal, germicidal and enzyme inhibitory properties. In the current work, synthesis of p-toluenesufonyl fluoride was accomplished by reacting p-toluenesulfonyl chloride with solid potassium fluoride using PEG-400 as a catalyst under...

Lithium plating and dendrite formation can occur on the graphite surface at high current densities. What is more, graphite generates a 10% volume change during cycling, resulting in a solid electrolyte interface (SEI) crack and further electrolyte decomposition. Here, p-Toluenesulfonyl isocyanat...

A series of novel p-toluenesulfonyl-hydrazinothiazoles and hydrazino-bis-thiazoles derivatives (2a–f, 3a–f and 5–8) were synthesized by initial condensation of p-toluenesulfonylthiosemicarbazide 1 with a series of α-halogenocarbonyls in acetone or dimethylformamide (DMF)/acetone, mixture. Al...

A silver-catalyzed reaction of 2-alkynylbenzaldoxime with phenol promoted by p-toluenesulfonyl chloride leads to 1-aroxyisoquinolines in good yields. The presence of p-toluenesulfonyl chloride as an activator is essential for the successful transformation.

The pore formation in the system resol resin – ethylene glycol – p-toluenesulfonyl chloride based on polymerization induced phase separation (PIPS), post-curing and pyrolysis techniques are studied by thermal analysis methods, pyrolysis gas chromatography mass spectrometry and electron microsc...