The three-dimensional molecular structure of the cyclic iron(III)-containing hexapeptide ferrichrysin, as elucidated from single crystal X-ray diffraction data, is described. The molecular conformation of this biologically active compound shows similarities with the one observed for the related ...

Based on studies using laboratory strains, the efficiency of gene disruption in Aspergillus oryzae, commonly known as koji mold, is low; thus, gene disruption has rarely been applied to the breeding of koji mold. To evaluate the efficiency of gene disruption in industrial strains of A. oryzae, w...

The complex [Cu(2,3-pydcH)2], (1), (2,3-pydcH2=2,3-pyridinedicarboxylic acid) is a chain polymer. Two ligands occupy the equatorial plane of each tetragonally elongated octahedral Cu2+ coordination sphere, chelating through the pyridine nitrogen and one oxygen of the deprotonated 2-carboxylic ac...

The reaction of zinc salts with heterocyclic ether (1-ethoxymethyl-2-methylimidazole (1-ExMe-2-MeIm)), acid (pyridine-2,3-dicarboxylic acid (2,3-pydcH2)) and amide (3,5-dimethylpyrazole-1-carboxamide (3,5-DMePzCONH2)) yielded three new zinc complexes formulated as [Zn(1-ExMe-2-MeIm)2Cl2] 1, fac-...

Three Co(II) and Cu(II)-pyridine-2,5-dicarboxylate (pydc) proton transfer compounds with 1,4-butanediamine (ben) and 2,2-dimethylpropane-1,3-diamine (dmpen), trans-(H2ben)[Co(pydc)2(H2O)2]·4H2O (1), trans-(H2dmpen)[Co(pydc)2(H2O)2]·2H2O (2) and (H2ben)2[Cu2(μ-pydc)4(H2O)2] (3) have been synth...

The preparation of a novel macrocyclic ligand (1), N,N′-diethylhomopiperazinyl,2,6-pyridinedicarboxylate and its Co(II), Ni(II), Cu(II), and Zn(II) complexes are described. The ligand was prepared in EtOH from the reaction of dipotassium salt of 2,6-pyridinedicarboxylic acid with 1,2-dibromoeth...

The present study reports the synthesis and evaluation of nonlinear optical property and G-Quadruplex DNA Stabilization of five novel copper(II) mixed ligand complexes. They were synthesized from copper(II) salt, 2,5- and 2,3- pyridinedicarboxylic acid, diethylenetriamine and amide based ligand ...

Compound DAPH+Cl−·3H2O (1), and complexes Mn(dipic)(H2O)3 (2) and [DAPH][Zn(dipicH)(dipic)]·4H2O (3), (dipicH2 = 2,6-pyridinedicarboxylic acid and DAP = 2,3-diaminophenazine) were prepared from the reaction of MgCl2·4H2O and ZnCl2 with mixture of o-phenylenediamine (OPD) and 2,6-pyridinedicar...

The complex [DAPH][H3O][Cu(dipic)2]·3H2O, (1) (dipicH2 = 2,6-pyridinedicarboxylic acid and DAP = 2,3-diaminophenazine) was prepared from the reaction of Cu(NO3)2·2H2O with mixture of o-phenylenediamine (OPD) and 2,6-pyridinedicarboxylic acid in water. The complex was characterized by FTIR, ele...

Six title copper(II)/zinc(II) coordination polymers have been synthesized, using the metal salt with different oxidation states (Cu(NO3)2/CuBr2/CuI/Zn(OAc)2), dicarboxylate ligand (2,3-pyridinedicarboxylic acid (pydc) or 2,3-pyrazinedicarboxylic acid (pzdc)) and the auxiliary ligand (2,2′-bpy, ...

A novel superacidic mesoporous catalyst UDCaT-4 was developed in this laboratory, which has been used in the alkylation of biphenyl with isopropanol. UDCaT-4 is a synergistic combination of persulfated alumina and zirconia with hexagonal mesoporous silica. 4,4′-Diisopropylbiphenyl (DIPB) has be...

Ceria-modification is an effective method for the deactivation of external acid sites of H-mordenite (HM). The selectivity for 4,4′-diisopropylbiphenyl (4,4′-DIPB) in the isopropylation of BP over dealuminated HM such as HM(128) decreased with raising reaction temperatures or with decreasing p...

Alkylation of biphenyl with propene was carried out at 250°C using H-mordenite as a catalyst. H-mordenite was selective for 4,4′-diisopropylbiphenyl(4,4′-DIPB) production. The 4,4′-DIPB selectivity, however, decreased with increasing level of biphenyl conversion, due to isomerization of 4,4′...

The roles of internal and external acid sites of a dealuminated H-mordenite (MOR; SiO2/Al2O3 = 128) on the selectivity for 4,4′-DIPB in the isopropylation of biphenyl (BP) are examined by changing catalyst amount. The isopropylation of BP gave high selectivity for 4,4′-DIPB at such a low tempe...

An anomalous fluorescence near 380 nm is detected from heptane solutions on naphtho[1,8-cd][1,2,6] thiadiazine (1), 6,7-dihydroacenaphtho[5,6-cd][1,2,6]thiadiazone (2), its unsaturated derivative (4), and the tetrachloro derivative of 1 (3), when these substances are excited into the S0→S2 abso...

Asymmetric 3,5-diaryl substituted 4H-1,2,6-thiadiazin-4-ones can be prepared from 3,5-dichloro-4H-1,2,6-thiadiazin-4-one (1) via a multi-step protocol: selective nucleophilic mono-chloro substitution gives either the mono-methoxy or benzyloxy substituted mono-chlorothiadiazinones that can be phe...

The base-free TiCl4-mediated condensation of 3,5-disubstituted-4H-1,2,6-thiadiazin-4-ones 8 with malononitrile affords 20 difficult to access (3,5-disubstituted-4H-1,2,6-thiadiazin-4-ylidene)malononitriles 7. The reaction tolerates 3,5-diaryl, diphenoxy, dimethoxy and diphenylthio substituted th...

3,5-Diaryl-4H-1,2,6-thiadiazin-4-ones react with NaBH4 to give the 3,5-diaryl-4H-1,2,6-thiadiazin-4-ols and with MeLi to give 4-methyl-3,5-diaryl-4H-1,2,6-thiadiazin-4-ols. The latter dehydrate with p-toluenesulfonic acid to give (3,5-diarylthiadiazin-4-ylidene)methanes. (3,5-Diphenyl-4H-1,2,6-t...

[3,5-Bis(dialkylamino)-4H-1,2,6-thiadiazin-4-ylidene]propanedinitriles 6a–c, react with sodium methoxide or ethoxide to give the corresponding 6-alkoxy-4-dialkylamino substituted pyrrolo[2,3-c][1,2,6]thiadiazine-5-carbonitriles 7a–f in variable yields. These new compounds are fully characteris...

Research suggests that attention deficit disorder (ADD) may persist into adulthood, perhaps predisposing certain individuals to stimulant abuse. The authors describe two adults with chronic cocaine abuse and apparent residual ADD. After failing to respond to conventional treatment modalities, th...